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ONTOLOGY REPORT - ANNOTATIONS

Term:atrioventricular valve development
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Accession:GO:0003171 term browser browse the term
Definition:The progression of the atrioventricular valve over time, from its formation to the mature structure.
Synonyms:exact_synonym: AV valve development

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atrioventricular valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor involved_in ISO (PMID:23603510) BHF-UCL PMID:23603510 NCBI chrNW_004955511:2,321,445...2,324,417
Ensembl chrNW_004955511:2,322,920...2,324,068 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:11854453) BHF-UCL PMID:11854453 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (PMID:15297376) MGI PMID:15297376 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030 		JBrowse link
G Pitx2 paired like homeodomain 2 acts_upstream_of_or_within ISO (PMID:18292603) MGI PMID:18292603 NCBI chrNW_004955457:15,803,493...15,823,193
Ensembl chrNW_004955457:15,803,219...15,823,310 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:21983003) BHF-UCL PMID:21983003 NCBI chrNW_004955460:7,794,313...7,856,906
Ensembl chrNW_004955460:7,794,313...7,856,906 		JBrowse link
atrioventricular valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata4 GATA binding protein 4 involved_in ISO (PMID:21330551) BHF-UCL PMID:21330551 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267 		JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (PMID:17259303) BHF-UCL PMID:17259303 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945 		JBrowse link
G Smad4 SMAD family member 4 involved_in ISO (PMID:21330551) BHF-UCL PMID:21330551 NCBI chrNW_004955402:35,956,080...36,001,746
Ensembl chrNW_004955402:35,961,165...35,994,538 		JBrowse link
atrioventricular valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:16140292) BHF-UCL PMID:16140292 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694 		JBrowse link
G Bmp2 bone morphogenetic protein 2 acts_upstream_of_or_within ISO (PMID:16314491) MGI PMID:16314491 NCBI chrNW_004955415:17,048,374...17,058,172
Ensembl chrNW_004955415:17,048,030...17,060,181 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (PMID:12441304) BHF-UCL PMID:12441304 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO (PMID:17023674) MGI PMID:17023674 NCBI chrNW_004955423:8,416,498...8,419,029
Ensembl chrNW_004955423:8,413,725...8,419,166 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO (PMID:19084512) MGI PMID:19084512 NCBI chrNW_004955403:52,958,318...53,029,267
Ensembl chrNW_004955403:52,987,644...53,029,267 		JBrowse link
G Hey1 hes related family bHLH transcription factor with YRPW motif 1 involved_in ISO (PMID:17303760) BHF-UCL PMID:17303760 NCBI chrNW_004955444:1,498,444...1,502,099
Ensembl chrNW_004955444:1,498,675...1,500,945 		JBrowse link
G Heyl hes related family bHLH transcription factor with YRPW motif like involved_in ISO (PMID:17303760) BHF-UCL PMID:17303760 NCBI chrNW_004955452:17,137,066...17,152,714
Ensembl chrNW_004955452:17,134,770...17,152,924 		JBrowse link
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO (PMID:22821713) MGI PMID:22821713 NCBI chrNW_004955458:15,264,028...15,287,290
Ensembl chrNW_004955458:15,263,739...15,286,808 		JBrowse link
G Mdm4 MDM4 regulator of p53 acts_upstream_of_or_within ISO (PMID:22821713) MGI PMID:22821713 NCBI chrNW_004955406:40,346,617...40,387,977
Ensembl chrNW_004955406:40,346,588...40,387,977 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:14701881), (PMID:21266778) BHF-UCL PMID:14701881 PMID:21266778 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in ISO (PMID:25691540) BHF-UCL PMID:25691540 NCBI chrNW_004955408:21,719,487...22,322,958
Ensembl chrNW_004955408:21,722,632...22,322,917 		JBrowse link
G Tbx5 T-box transcription factor 5 acts_upstream_of_or_within ISO (PMID:19084512) MGI PMID:19084512 NCBI chrNW_004955455:16,133,130...16,217,894
Ensembl chrNW_004955455:16,132,975...16,217,953 		JBrowse link
G Tgfb2 transforming growth factor beta 2 involved_in ISO (PMID:9217007) BHF-UCL PMID:9217007 NCBI chrNW_004955406:174,949...249,248
Ensembl chrNW_004955406:172,814...249,248 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (PMID:20652948) BHF-UCL PMID:20652948 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837 		JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (PMID:14614148) BHF-UCL PMID:14614148 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
mitral valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dchs1 dachsous cadherin-related 1 acts_upstream_of_or_within ISO (PMID:35200715) MGI PMID:35200715 NCBI chrNW_004955414:22,331,590...22,365,761
Ensembl chrNW_004955414:22,332,059...22,351,576 		JBrowse link
G Gja5 gap junction protein alpha 5 involved_in ISO (PMID:22199024) BHF-UCL PMID:22199024 NCBI chrNW_004955568:635,319...652,692
Ensembl chrNW_004955568:635,042...653,349 		JBrowse link
G Lix1l limb and CNS expressed 1 like acts_upstream_of_or_within ISO (PMID:35200715) MGI PMID:35200715 NCBI chrNW_004955568:136,482...158,531
Ensembl chrNW_004955568:136,589...157,991 		JBrowse link
mitral valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dchs1 dachsous cadherin-related 1 involved_in ISO (PMID:26258302) UniProt PMID:26258302 NCBI chrNW_004955414:22,331,590...22,365,761
Ensembl chrNW_004955414:22,332,059...22,351,576 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100) BHF-UCL PMID:16025100 NCBI chrNW_004955513:4,225,939...4,264,875
Ensembl chrNW_004955513:4,225,956...4,263,259 		JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (PMID:14614148) BHF-UCL PMID:14614148 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
mitral valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (PMID:19506109) BHF-UCL PMID:19506109 NCBI chrNW_004955449:15,587,958...15,706,432
Ensembl chrNW_004955449:15,640,230...15,708,694 		JBrowse link
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif 19 involved_in ISO (PMID:31844321) BHF-UCL PMID:31844321 NCBI chrNW_004955415:2,384,530...2,617,454
Ensembl chrNW_004955415:2,384,530...2,617,780 		JBrowse link
G Axin2 axin 2 involved_in ISO (PMID:28069701) BHF-UCL PMID:28069701 NCBI chrNW_004955478:4,952,551...4,982,223
Ensembl chrNW_004955478:4,952,488...4,982,225 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:16037571) BHF-UCL PMID:16037571 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:19409885) BHF-UCL PMID:19409885 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Dchs1 dachsous cadherin-related 1 involved_in
acts_upstream_of_or_within		 ISO (PMID:26258302) MGI PMID:26258302 NCBI chrNW_004955414:22,331,590...22,365,761
Ensembl chrNW_004955414:22,332,059...22,351,576 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (PMID:20960543) BHF-UCL PMID:20960543 NCBI chrNW_004955545:1,610,929...1,617,217
Ensembl chrNW_004955545:1,610,929...1,617,460 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO (PMID:26147524) MGI PMID:26147524 NCBI chrNW_004955451:16,445,338...16,449,243
Ensembl chrNW_004955451:16,445,338...16,450,062 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:10655064) BHF-UCL PMID:10655064 NCBI chrNW_004955450:9,005,332...9,070,790 JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (PMID:16109771) BHF-UCL PMID:16109771 NCBI chrNW_004955483:5,076,664...5,077,059 JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746) BHF-UCL PMID:20804746 NCBI chrNW_004955410:22,003,981...22,005,483 JBrowse link
tricuspid valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:15843409) BHF-UCL PMID:15843409 NCBI chrNW_004955460:7,794,313...7,856,906
Ensembl chrNW_004955460:7,794,313...7,856,906 		JBrowse link
tricuspid valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO (PMID:15297376) MGI PMID:15297376 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030 		JBrowse link
G Zfpm1 zinc finger protein, FOG family member 1 involved_in ISO (PMID:14614148) BHF-UCL PMID:14614148 NCBI chrNW_004955541:2,461,690...2,495,614 JBrowse link
tricuspid valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts19 ADAM metallopeptidase with thrombospondin type 1 motif 19 involved_in ISO (PMID:32323311) BHF-UCL PMID:32323311 NCBI chrNW_004955415:2,384,530...2,617,454
Ensembl chrNW_004955415:2,384,530...2,617,780 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (PMID:16037571) BHF-UCL PMID:16037571 NCBI chrNW_004955510:5,812,571...5,936,312
Ensembl chrNW_004955510:5,905,008...5,936,312 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (PMID:19409885) BHF-UCL PMID:19409885 NCBI chrNW_004955457:12,235,780...12,315,680
Ensembl chrNW_004955457:12,235,780...12,316,727 		JBrowse link
G Hey2 hes related family bHLH transcription factor with YRPW motif 2 involved_in ISO (PMID:12372254) BHF-UCL PMID:12372254 NCBI chrNW_004955436:7,060,930...7,070,610
Ensembl chrNW_004955436:7,060,930...7,070,030 		JBrowse link
G Tgfbr2 transforming growth factor beta receptor 2 involved_in ISO (PMID:20652948) BHF-UCL PMID:20652948 NCBI chrNW_004955430:21,919,338...21,999,688
Ensembl chrNW_004955430:21,932,553...22,001,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12600
    developmental process 5987
      anatomical structure development 5659
        heart valve development 70
          atrioventricular valve development 31
            atrioventricular valve morphogenesis + 26
            mitral valve development + 15
            tricuspid valve development + 7
Path 2
Term Annotations click to browse term
  biological_process 12600
    developmental process 5987
      anatomical structure development 5659
        multicellular organism development 4628
          system development 4029
            circulatory system development 1174
              heart development 672
                heart valve development 70
                  atrioventricular valve development 31
                    atrioventricular valve morphogenesis + 26
                    mitral valve development + 15
                    tricuspid valve development + 7
paths to the root