Gata4 (GATA binding protein 4) - Rat Genome Database

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Gene: Gata4 (GATA binding protein 4) Chinchilla lanigera
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Symbol: Gata4
Name: GATA binding protein 4
RGD ID: 9016990
Description: ENCODES a protein that exhibits chromatin binding (ortholog); cis-regulatory region sequence-specific DNA binding (ortholog); co-SMAD binding (ortholog); INVOLVED IN aortic valve morphogenesis (ortholog); atrial septum morphogenesis (ortholog); atrial septum primum morphogenesis (ortholog); ASSOCIATED WITH 46,XY sex reversal 3 (ortholog); alcohol use disorder (ortholog); Animal Disease Models (ortholog); FOUND IN chromatin (ortholog); nuclear body (ortholog); nucleus (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Also known as: transcription factor GATA-4
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,987,644 - 53,029,267 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540352,958,318 - 53,029,267 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aortic valve morphogenesis  (ISO)
atrial septum morphogenesis  (ISO)
atrial septum primum morphogenesis  (ISO)
atrial septum secundum morphogenesis  (ISO)
atrioventricular canal development  (ISO)
atrioventricular valve formation  (ISO)
atrioventricular valve morphogenesis  (ISO)
cardiac muscle cell differentiation  (ISO)
cardiac muscle hypertrophy in response to stress  (ISO)
cardiac muscle tissue development  (ISO)
cardiac muscle tissue regeneration  (ISO)
cardiac right ventricle morphogenesis  (ISO)
cardiac septum development  (ISO)
cell growth involved in cardiac muscle cell development  (ISO)
cell-cell signaling  (ISO)
cellular response to follicle-stimulating hormone stimulus  (ISO)
cellular response to glucose stimulus  (ISO)
cellular response to gonadotropin stimulus  (ISO)
embryonic digestive tract morphogenesis  (ISO)
embryonic foregut morphogenesis  (ISO)
embryonic heart tube anterior/posterior pattern specification  (ISO)
embryonic heart tube development  (ISO)
embryonic morphogenesis  (ISO)
endocardial cushion development  (ISO)
endoderm formation  (ISO)
epithelial cell fate commitment  (ISO)
gastrulation with mouth forming second  (ISO)
heart development  (ISO)
heart looping  (ISO)
heart morphogenesis  (ISO)
in utero embryonic development  (ISO)
intestinal epithelial cell differentiation  (ISO)
lung lobe formation  (ISO)
male gonad development  (ISO)
negative regulation of apoptotic process  (ISO)
negative regulation of apoptotic signaling pathway  (ISO)
negative regulation of autophagy  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of connective tissue replacement  (ISO)
negative regulation of gene expression  (ISO)
negative regulation of oxidative stress-induced cell death  (ISO)
positive regulation of angiogenesis  (ISO)
positive regulation of BMP signaling pathway  (ISO)
positive regulation of cardiac muscle cell proliferation  (ISO)
positive regulation of cardioblast differentiation  (ISO)
positive regulation of cell cycle  (ISO)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of transcription by RNA polymerase II  (ISO)
positive regulation of transcription, DNA-templated  (ISO)
positive regulation of vascular endothelial growth factor production  (ISO)
regulation of cardiac muscle cell contraction  (ISO)
regulation of cardiac muscle cell proliferation  (ISO)
regulation of gene expression  (ISO)
regulation of protein kinase B signaling  (ISO)
regulation of transcription by RNA polymerase II  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to estrogen  (ISO)
response to mechanical stimulus  (ISO)
response to retinoic acid  (ISO)
response to vitamin A  (ISO)
response to xenobiotic stimulus  (ISO)
seminiferous tubule development  (ISO)
Sertoli cell differentiation  (ISO)
signal transduction involved in regulation of gene expression  (ISO)
SMAD protein signal transduction  (ISO)
spermatogenesis  (ISO)
transdifferentiation  (ISO)
tube morphogenesis  (ISO)
ventricular cardiac muscle tissue development  (ISO)
ventricular septum development  (ISO)
wound healing  (ISO)

Cellular Component

References


Genomics

Comparative Map Data
Gata4
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540352,987,644 - 53,029,267 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540352,958,318 - 53,029,267 (+)NCBIChiLan1.0ChiLan1.0
GATA4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl811,676,959 - 11,760,002 (+)EnsemblGRCh38hg38GRCh38
GRCh38811,676,935 - 11,760,002 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37811,534,444 - 11,617,511 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36811,599,162 - 11,654,918 (+)NCBINCBI36hg18NCBI36
Build 34811,599,161 - 11,654,918NCBI
Celera810,690,994 - 10,746,848 (+)NCBI
Cytogenetic Map8p23.1NCBI
HuRef810,492,698 - 10,548,485 (+)NCBIHuRef
CHM1_1811,627,233 - 11,683,005 (+)NCBICHM1_1
Gata4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391463,436,363 - 63,509,161 (-)NCBIGRCm39mm39
GRCm39 Ensembl1463,436,371 - 63,509,141 (-)Ensembl
GRCm381463,198,914 - 63,271,712 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1463,198,922 - 63,271,692 (-)EnsemblGRCm38mm10GRCm38
MGSCv371463,817,752 - 63,864,097 (-)NCBIGRCm37mm9NCBIm37
MGSCv361462,153,032 - 62,199,370 (-)NCBImm8
Celera1460,962,648 - 61,008,982 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1433.24NCBI
Gata4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21537,459,601 - 37,531,291 (-)NCBImRatBN7.2
Rnor_6.0 Ensembl1546,386,712 - 46,432,965 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01546,386,703 - 46,458,679 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01550,151,497 - 50,197,708 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41542,472,793 - 42,519,569 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11542,488,492 - 42,535,269 (-)NCBI
Celera1537,143,928 - 37,189,874 (-)NCBICelera
RH 3.4 Map15261.71RGD
Cytogenetic Map15p12NCBI
GATA4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Mhudiblu_PPA_v087,442,921 - 7,526,731 (-)NCBIMhudiblu_PPA_v0panPan3
GATA4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12526,126,172 - 26,211,474 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2526,127,853 - 26,182,989 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2526,784,428 - 26,835,191 (-)NCBI
ROS_Cfam_1.02526,280,507 - 26,366,154 (-)NCBI
UMICH_Zoey_3.12526,235,249 - 26,286,037 (-)NCBI
UNSW_CanFamBas_1.02526,131,847 - 26,182,607 (-)NCBI
UU_Cfam_GSD_1.02526,283,313 - 26,334,650 (-)NCBI
Gata4
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049435,165,238 - 5,177,602 (-)NCBI
SpeTri2.0NW_0049366753,408,549 - 3,420,828 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GATA4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1414,858,159 - 14,939,941 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11414,858,470 - 14,938,156 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21416,046,527 - 16,126,816 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GATA4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.187,348,145 - 7,432,574 (-)NCBI
ChlSab1.1 Ensembl87,349,660 - 7,400,562 (-)Ensembl
Vero_WHO_p1.0NW_02366605235,034,077 - 35,087,089 (+)NCBI
Gata4
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475825,278,878 - 25,319,317 (+)NCBI


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSCLAT00000023976   ⟹   ENSCLAP00000023750
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_00495540352,987,644 - 53,029,267 (+)Ensembl
RefSeq Acc Id: XM_005373824   ⟹   XP_005373881
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540352,979,256 - 53,029,267 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514543   ⟹   XP_013369997
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540352,979,256 - 53,029,267 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514548   ⟹   XP_013370002
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540352,979,317 - 53,029,267 (+)NCBI
Sequence:
RefSeq Acc Id: XM_013514552   ⟹   XP_013370006
RefSeq Status:
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_00495540352,958,318 - 53,029,267 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_005373881 (Get FASTA)   NCBI Sequence Viewer  
  XP_013369997 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370002 (Get FASTA)   NCBI Sequence Viewer  
  XP_013370006 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: XP_005373881   ⟸   XM_005373824
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013370006   ⟸   XM_013514552
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013369997   ⟸   XM_013514543
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013370002   ⟸   XM_013514548
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: ENSCLAP00000023750   ⟸   ENSCLAT00000023976


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000016297 Ensembl, ENTREZGENE
Ensembl Protein ENSCLAP00000023750 ENTREZGENE
Ensembl Transcript ENSCLAT00000023976 ENTREZGENE
NCBI Gene Gata4 ENTREZGENE