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ONTOLOGY REPORT - ANNOTATIONS

Term:heart valve development
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Accession:GO:0003170 term browser browse the term
Definition:The progression of a heart valve over time, from its formation to the mature structure. A heart valve is a structure that restricts the flow of blood to different regions of the heart and forms from an endocardial cushion.
Synonyms:exact_synonym: cardiac valve development


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heart valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:5644076 NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053 		JBrowse link
G Matr3 matrin 3 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (MGI:5636584|PMID:25574029)
GO_REF:0000107		 RGD
Ensembl		 PMID:25574029 GO_REF:0000107 MGI:5636584 NCBI chr18:27,154,098...27,193,212
Ensembl chr18:27,163,714...27,193,166 		JBrowse link
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO MGI:107934 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 acts_upstream_of_or_within ISO MGI:96952 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:5819191|PMID:26147524) RGD PMID:26147524 MGI:5819191 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Pde2a phosphodiesterase 2A acts_upstream_of_or_within ISO (MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:5644076 NCBI chr 1:155,823,590...155,915,434
Ensembl chr 1:155,813,180...155,915,434 		JBrowse link
G Prdm1 PR/SET domain 1 acts_upstream_of_or_within ISO (MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:5644076 NCBI chr20:47,959,858...47,981,488
Ensembl chr20:47,959,858...47,981,488 		JBrowse link
G Shox2 SHOX homeobox 2 acts_upstream_of_or_within ISO MGI:3794658 (MGI:3793891|PMID:17372176) RGD PMID:17372176 MGI:3793891 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
G Smad6 SMAD family member 6 acts_upstream_of_or_within ISO (MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:5644076 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISS
ISO		 GO_REF:0000024
(MGI:4947506|PMID:20056916)		 UniProt
RGD		 PMID:20056916 GO_REF:0000024 MGI:4947506 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Zbtb14 zinc finger and BTB domain containing 14 acts_upstream_of_or_within ISO (MGI:5644076|PMID:25807483) RGD PMID:25807483 MGI:5644076 NCBI chr 9:109,333,440...109,338,646
Ensembl chr 9:109,331,028...109,338,632 		JBrowse link
aortic valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(MGI:3640731|PMID:16730346)		 Ensembl
RGD		 PMID:16730346 GO_REF:0000107 MGI:3640731 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO GO:1905314 (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO UniProtKB:P25119 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
aortic valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdh11 cadherin 11 involved_in ISO UniProtKB:P61586 (PMID:26188246) RGD PMID:26188246 NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272 		JBrowse link
G Rhoa ras homolog family member A involved_in ISO
IEA		 UniProtKB:F1RFU7 (PMID:26188246)
GO_REF:0000107		 RGD
Ensembl		 PMID:26188246 GO_REF:0000107 NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746 		JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 involved_in ISO (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Axin2 axin 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6108194|PMID:28069701)		 Ensembl
RGD		 PMID:28069701 GO_REF:0000107 MGI:6108194 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Dll4 delta like canonical Notch ligand 4 involved_in ISO
IEA		 (PMID:26491108)
GO_REF:0000107		 RGD
Ensembl		 PMID:26491108 GO_REF:0000107 NCBI chr 3:106,317,114...106,327,004
Ensembl chr 3:106,316,986...106,326,931 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Eln elastin involved_in IEA
ISO		 GO_REF:0000107
(MGI:5142190|PMID:20576933)		 Ensembl
RGD		 PMID:20576933 GO_REF:0000107 MGI:5142190 NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928 		JBrowse link
G Emilin1 elastin microfibril interfacer 1 involved_in ISO (MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:5605894 NCBI chr 6:25,455,974...25,463,713
Ensembl chr 6:25,445,298...25,463,698 		JBrowse link
G Gata3 GATA binding protein 3 involved_in ISO (MGI:3832106|PMID:18955134) RGD PMID:18955134 MGI:3832106 NCBI chr17:68,643,760...68,666,000
Ensembl chr17:68,643,873...68,665,391 		JBrowse link
G Gata4 GATA binding protein 4 involved_in ISO (PMID:29325903) RGD PMID:29325903 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Gata5 GATA binding protein 5 involved_in ISO (PMID:22641149), (PMID:24638895)
(MGI:5286818|PMID:21633169)		 RGD PMID:21633169 PMID:22641149 PMID:24638895 MGI:5286818 NCBI chr 3:167,418,563...167,426,751
Ensembl chr 3:167,418,565...167,426,751 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:6158746|PMID:22110751) RGD PMID:22110751 MGI:6158746 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:1197815 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:3609262|PMID:10821808), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 Ensembl
RGD		 PMID:10821808 PMID:23583836 PMID:27107132 GO_REF:0000107 MGI:3609262 MGI:6158784 MGI:6158885 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132), (MGI:6158885|PMID:23583836)		 RGD PMID:16025100 PMID:17662764 PMID:18593716 PMID:23583836 PMID:26491108 More... MGI:6158728 MGI:6158784 MGI:6158885 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Rb1 RB transcriptional corepressor 1 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6112863|PMID:29304157)		 Ensembl
RGD		 PMID:29304157 GO_REF:0000107 MGI:6112863 NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 involved_in ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,114,532...1,236,345
Ensembl chr18:1,115,905...1,235,571 		JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 involved_in ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5913048|PMID:25691540)		 Ensembl
RGD		 PMID:25691540 GO_REF:0000107 MGI:5913048 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO UniProtKB:Q9R001 (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (PMID:22275001) RGD PMID:22275001 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in ISO (PMID:22110751) RGD PMID:22110751 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (PMID:18275040), (PMID:18834961) RGD PMID:18275040 PMID:18834961 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (PMID:26634652)
(MGI:5921830|PMID:26634652)		 RGD PMID:26634652 MGI:5921830 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (PMID:20101701)
GO_REF:0000107		 RGD
Ensembl		 PMID:20101701 GO_REF:0000107 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 involved_in ISO (MGI:6370101|PMID:31319059) RGD PMID:31319059 MGI:6370101 NCBI chr 5:132,000,013...132,019,658
Ensembl chr 5:132,000,015...132,019,592 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)		 RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
atrioventricular valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aplnr apelin receptor involved_in ISO (MGI:5584055|PMID:23603510) RGD PMID:23603510 MGI:5584055 NCBI chr 3:70,217,407...70,221,052
Ensembl chr 3:70,217,385...70,221,050 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:2175930|PMID:11854453) RGD PMID:11854453 MGI:2175930 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:3574394 (MGI:3574376|PMID:15297376) RGD PMID:15297376 MGI:3574376 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Pitx2 paired-like homeodomain 2 acts_upstream_of_or_within ISO MGI:1857844|MGI:2386742 (MGI:3841866|PMID:18292603) RGD PMID:18292603 MGI:3841866 NCBI chr 2:217,717,738...217,737,293
Ensembl chr 2:217,717,693...217,737,293 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:5299248|PMID:21983003) RGD PMID:21983003 MGI:5299248 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
atrioventricular valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gata4 GATA binding protein 4 involved_in ISO UniProtKB:P97471 (MGI:4946551|PMID:21330551) RGD PMID:21330551 MGI:4946551 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO (MGI:3703467|PMID:17259303) RGD PMID:17259303 MGI:3703467 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Olfm1 olfactomedin 1 involved_in ISS GO_REF:0000024 AgBase GO_REF:0000024 NCBI chr 3:11,520,522...11,558,240
Ensembl chr 3:11,520,729...11,558,239 		JBrowse link
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q08369 (MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
atrioventricular valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO (MGI:3610266|PMID:16140292) RGD PMID:16140292 MGI:3610266 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Bmp2 bone morphogenetic protein 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:3583785 (MGI:3611958|PMID:16314491)		 Ensembl
RGD		 PMID:16314491 GO_REF:0000107 MGI:3611958 NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 NOT|involved_in ISO (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Ccn1 cellular communication network factor 1 acts_upstream_of_or_within ISO MGI:2446577 (MGI:3761425|PMID:17023674) RGD PMID:17023674 MGI:3761425 NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484 		JBrowse link
G Gata4 GATA binding protein 4 acts_upstream_of_or_within ISO MGI:102541 (MGI:3833786|PMID:19084512) RGD PMID:19084512 MGI:3833786 NCBI chr15:37,459,601...37,531,291
Ensembl chr15:37,459,601...37,505,636 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Mdm2 MDM2 proto-oncogene acts_upstream_of_or_within ISO MGI:107934 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Mdm4 MDM4 regulator of p53 acts_upstream_of_or_within ISO MGI:96952 (MGI:5440773|PMID:22821713) RGD PMID:22821713 MGI:5440773 NCBI chr13:44,432,596...44,516,165
Ensembl chr13:44,406,213...44,474,226 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:3027664|PMID:14701881), (MGI:5000164|PMID:21266778) RGD PMID:14701881 PMID:21266778 MGI:3027664 MGI:5000164 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Slit3 slit guidance ligand 3 involved_in IEA
ISO		 GO_REF:0000107
(MGI:5913048|PMID:25691540)		 Ensembl
RGD		 PMID:25691540 GO_REF:0000107 MGI:5913048 NCBI chr10:19,571,798...20,156,634
Ensembl chr10:19,571,684...20,156,634 		JBrowse link
G Tbx5 T-box transcription factor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:95664 (MGI:3833786|PMID:19084512)		 Ensembl
RGD		 PMID:19084512 GO_REF:0000107 MGI:3833786 NCBI chr12:36,686,344...36,739,253
Ensembl chr12:36,688,014...36,734,885 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO (MGI:4821522|PMID:20652948) RGD PMID:20652948 MGI:4821522 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
cell proliferation involved in heart valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (PMID:20804746)
(MGI:4838344|PMID:20804746)		 RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
coronary sinus valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Erg ETS transcription factor ERG acts_upstream_of_or_within ISO MGI:5443838 (MGI:5442628|PMID:22932696) RGD PMID:22932696 MGI:5442628 NCBI chr11:34,678,614...34,900,951
Ensembl chr11:34,678,618...34,845,871 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 acts_upstream_of_or_within ISO MGI:1341884 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:1341800 (MGI:3530185|PMID:15680351) RGD PMID:15680351 MGI:3530185 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) RGD PMID:18802027 MGI:4413438 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sox9 SRY-box transcription factor 9 acts_upstream_of_or_within ISO MGI:2385468|MGI:2450311 (MGI:3709829|PMID:17350610) RGD PMID:17350610 MGI:3709829 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 involved_in ISO (MGI:4452308|PMID:20096780) RGD PMID:20096780 MGI:4452308 NCBI chr 4:125,290,633...125,462,988
Ensembl chr 4:125,291,490...125,462,929 		JBrowse link
G Fgfrl1 fibroblast growth factor receptor-like 1 acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3849002 (MGI:3848851|PMID:19383940)
GO_REF:0000107		 RGD
Ensembl		 PMID:19383940 GO_REF:0000107 MGI:3848851 NCBI chr14:1,009,863...1,022,620
Ensembl chr14:1,009,786...1,021,928 		JBrowse link
G Mtor mechanistic target of rapamycin kinase acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:3850506 (MGI:5632243|PMID:25139234)
GO_REF:0000107		 RGD
Ensembl		 PMID:25139234 GO_REF:0000107 MGI:5632243 NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181766 (MGI:1197816|PMID:9515963) RGD PMID:9515963 MGI:1197816 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Scx scleraxis bHLH transcription factor involved_in ISO (MGI:4413438|PMID:18802027) RGD PMID:18802027 MGI:4413438 NCBI chr 7:108,176,608...108,178,626
Ensembl chr 7:108,176,608...108,178,626 		JBrowse link
G Sox9 SRY-box transcription factor 9 involved_in
acts_upstream_of_or_within		 ISS
ISO		 GO_REF:0000024
MGI:2176070|MGI:2385468 (MGI:3709829|PMID:17350610)		 UniProt
RGD		 PMID:17350610 GO_REF:0000024 MGI:3709829 NCBI chr10:97,806,485...97,811,994
Ensembl chr10:97,806,485...97,811,994 		JBrowse link
G Tgfb1 transforming growth factor, beta 1 involved_in ISO (MGI:67103|PMID:8009224) RGD PMID:8009224 MGI:67103 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in
acts_upstream_of_or_within		 ISO (MGI:3609313|PMID:11390347)
MGI:1888389 (MGI:5140242|PMID:21780244)		 RGD PMID:11390347 PMID:21780244 MGI:3609313 MGI:5140242 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
mitral valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
mitral valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dchs1 dachsous cadherin-related 1 involved_in ISO (PMID:26258302) RGD PMID:26258302 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100) RGD PMID:16025100 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
mitral valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acvr1 activin A receptor type 1 involved_in ISO
IEA		 (PMID:19506109)
GO_REF:0000107		 RGD
Ensembl		 PMID:19506109 GO_REF:0000107 NCBI chr 3:42,978,558...43,097,892
Ensembl chr 3:42,978,561...43,098,241 		JBrowse link
G Axin2 axin 2 involved_in IEA
ISO		 GO_REF:0000107
(MGI:6108194|PMID:28069701)		 Ensembl
RGD		 PMID:28069701 GO_REF:0000107 MGI:6108194 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) RGD PMID:16037571 MGI:3653945 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Dchs1 dachsous cadherin-related 1 acts_upstream_of_or_within
involved_in		 ISO MGI:4867020 (MGI:5694502|PMID:26258302) RGD PMID:26258302 MGI:5694502 NCBI chr 1:160,104,931...160,138,958
Ensembl chr 1:160,104,931...160,124,808 		JBrowse link
G Efna1 ephrin A1 involved_in ISO (MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:4847981 NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866 		JBrowse link
G Naglu N-acetyl-alpha-glucosaminidase acts_upstream_of_or_within ISO MGI:1934018 (MGI:5819191|PMID:26147524) RGD PMID:26147524 MGI:5819191 NCBI chr10:86,001,545...86,009,049
Ensembl chr10:86,001,566...86,008,972 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Sox4 SRY-box transcription factor 4 involved_in ISO (MGI:3603061|PMID:16109771) RGD PMID:16109771 MGI:3603061 NCBI chr17:35,667,809...35,672,515
Ensembl chr17:35,667,537...35,673,665 		JBrowse link
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
negative regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
positive regulation of cell proliferation involved in heart valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:4946551|PMID:21330551)		 Ensembl
RGD		 PMID:21330551 GO_REF:0000107 MGI:4946551 NCBI chr18:67,243,742...67,274,438
Ensembl chr18:67,243,742...67,274,438 		JBrowse link
positive regulation of endocardial cushion to mesenchymal transition involved in heart valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Twist1 twist family bHLH transcription factor 1 involved_in ISO (MGI:4838344|PMID:20804746) RGD PMID:20804746 MGI:4838344 NCBI chr 6:50,674,910...50,676,904
Ensembl chr 6:50,674,678...50,677,653 		JBrowse link
pulmonary valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO GO:1905314 (MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:2429424 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region involved_in ISO (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr14:57,338,493...57,523,330
Ensembl chr14:57,338,507...57,523,353 		JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A involved_in ISO UniProtKB:P25119 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B involved_in ISO UniProtKB:P25118 (MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:6158728 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
pulmonary valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 involved_in ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952 		JBrowse link
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 involved_in ISO (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr11:25,000,627...25,047,205
Ensembl chr11:25,000,637...25,047,205 		JBrowse link
G Bmp4 bone morphogenetic protein 4 involved_in IEA
ISO		 GO_REF:0000107
(MGI:3039210|PMID:15070745), (MGI:3814273|PMID:18924235)		 Ensembl
RGD		 PMID:15070745 PMID:18924235 GO_REF:0000107 MGI:3039210 MGI:3814273 NCBI chr15:19,618,538...19,633,494
Ensembl chr15:19,618,542...19,623,306 		JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 involved_in ISO UniProtKB:Q9DBX7 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 2:93,096,605...93,100,316
Ensembl chr 2:93,095,498...93,100,312 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like involved_in ISO UniProtKB:Q9WV93 (MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:3783952 NCBI chr 5:135,508,160...135,525,152
Ensembl chr 5:135,508,160...135,525,152 		JBrowse link
G Jag1 jagged canonical Notch ligand 1 involved_in IEA
ISO		 GO_REF:0000107
(PMID:20437614), (PMID:9207787)		 Ensembl
RGD		 PMID:9207787 PMID:20437614 GO_REF:0000107 NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 acts_upstream_of_or_within ISO MGI:2181762 (MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:1197815 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
G Nos3 nitric oxide synthase 3 involved_in IEA
ISO		 GO_REF:0000107
UniProtKB:Q01705 (MGI:6158784|PMID:27107132)		 Ensembl
RGD		 PMID:27107132 GO_REF:0000107 MGI:6158784 NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Notch1 notch receptor 1 involved_in ISO (PMID:16025100)
UniProtKB:P70313 (MGI:6158728|PMID:26491108), (MGI:6158784|PMID:27107132)		 RGD PMID:16025100 PMID:26491108 PMID:27107132 MGI:6158728 MGI:6158784 NCBI chr 3:9,277,955...9,323,531
Ensembl chr 3:9,278,086...9,323,531 		JBrowse link
G Notch2 notch receptor 2 involved_in ISO
IEA		 (PMID:16773578)
GO_REF:0000107		 RGD
Ensembl		 PMID:16773578 GO_REF:0000107 NCBI chr 2:185,610,594...185,744,088
Ensembl chr 2:185,610,589...185,744,088 		JBrowse link
G Robo1 roundabout guidance receptor 1 involved_in ISO UniProtKB:Q7TPD3 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:10,580,863...11,621,675
Ensembl chr11:10,580,908...11,620,203 		JBrowse link
G Robo2 roundabout guidance receptor 2 involved_in ISO UniProtKB:O89026 (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr11:12,528,949...14,096,726
Ensembl chr11:12,528,951...13,041,536 		JBrowse link
G Slit2 slit guidance ligand 2 involved_in ISO (MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:5913048 NCBI chr14:62,616,337...62,955,934
Ensembl chr14:62,617,067...62,955,948 		JBrowse link
G Smad2 SMAD family member 2 involved_in ISO UniProtKB:Q9R001 (MGI:5693221|PMID:23531444) RGD PMID:23531444 MGI:5693221 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323 		JBrowse link
G Smad6 SMAD family member 6 involved_in ISO (MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:1352979 NCBI chr 8:64,450,114...64,519,673
Ensembl chr 8:64,450,114...64,519,763 		JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 involved_in ISO
IEA		 (PMID:17273977)
GO_REF:0000107		 RGD
Ensembl		 PMID:17273977 GO_REF:0000107 NCBI chr 8:58,548,899...58,568,861
Ensembl chr 8:58,549,736...58,568,860 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 involved_in ISO (MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:894212 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
semi-lunar valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:2429424|PMID:12441304), (MGI:3851675|PMID:19409885) RGD PMID:12441304 PMID:19409885 MGI:2429424 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 involved_in ISO (MGI:5319103|PMID:22300732) RGD PMID:22300732 MGI:5319103 NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028 		JBrowse link
sinoatrial valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Shox2 SHOX homeobox 2 involved_in ISO
IEA		 (MGI:3836832|PMID:19166829)
GO_REF:0000107		 RGD
Ensembl		 PMID:19166829 GO_REF:0000107 MGI:3836832 NCBI chr 2:151,217,049...151,227,180
Ensembl chr 2:151,217,552...151,227,143 		JBrowse link
sinoatrial valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mef2c myocyte enhancer factor 2C involved_in ISS
ISO		 GO_REF:0000024
(MGI:3830899|PMID:16680724)		 UniProt
RGD		 PMID:16680724 GO_REF:0000024 MGI:3830899 NCBI chr 2:13,973,299...14,136,065
Ensembl chr 2:13,993,438...14,132,880 		JBrowse link
tricuspid valve development term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Tbx20 T-box transcription factor 20 involved_in ISO (MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:3604925 NCBI chr 8:23,200,104...23,258,218
Ensembl chr 8:23,204,507...23,258,175 		JBrowse link
tricuspid valve formation term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 acts_upstream_of_or_within ISO MGI:3574394 (MGI:3574376|PMID:15297376) RGD PMID:15297376 MGI:3574376 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Zfpm1 zinc finger protein, multitype 1 involved_in ISO (MGI:3583527|PMID:14614148) RGD PMID:14614148 MGI:3583527 NCBI chr19:50,334,352...50,391,029
Ensembl chr19:50,334,682...50,390,591 		JBrowse link
tricuspid valve morphogenesis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr1a bone morphogenetic protein receptor type 1A involved_in ISO (MGI:3653945|PMID:16037571) RGD PMID:16037571 MGI:3653945 NCBI chr16:9,736,390...9,829,825
Ensembl chr16:9,736,630...9,780,616 		JBrowse link
G Bmpr2 bone morphogenetic protein receptor type 2 involved_in ISO (MGI:3851675|PMID:19409885) RGD PMID:19409885 MGI:3851675 NCBI chr 9:61,192,718...61,307,280
Ensembl chr 9:61,190,566...61,301,809 		JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 involved_in ISO (MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:2386835 NCBI chr 1:26,822,131...26,832,218
Ensembl chr 1:26,822,131...26,832,218 		JBrowse link
G Tgfbr2 transforming growth factor, beta receptor 2 involved_in ISO
IEA		 (MGI:4821522|PMID:20652948)
GO_REF:0000107		 RGD
Ensembl		 PMID:20652948 GO_REF:0000107 MGI:4821522 NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19574
    developmental process 6911
      anatomical structure development 6438
        heart valve development 69
          atrioventricular valve development + 30
          cell proliferation involved in heart valve development + 4
          coronary sinus valve development + 1
          heart valve cell differentiation 0
          heart valve morphogenesis + 58
          semi-lunar valve development + 43
          sinoatrial valve development + 2
          ventriculo bulbo valve development + 0
Path 2
Term Annotations click to browse term
  biological_process 19574
    developmental process 6911
      anatomical structure development 6438
        multicellular organism development 5180
          system development 4459
            circulatory system development 1357
              heart development 736
                heart valve development 69
                  atrioventricular valve development + 30
                  cell proliferation involved in heart valve development + 4
                  coronary sinus valve development + 1
                  heart valve cell differentiation 0
                  heart valve morphogenesis + 58
                  semi-lunar valve development + 43
                  sinoatrial valve development + 2
                  ventriculo bulbo valve development + 0
paths to the root