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ONTOLOGY REPORT - ANNOTATIONS


Term:ganglioside metabolic process
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Accession:GO:0001573 term browser browse the term
Definition:The chemical reactions and pathways involving ceramide oligosaccharides carrying in addition to other sugar residues, one or more sialic acid residues.
Synonyms:exact_synonym: ganglioside metabolism



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ganglioside metabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca2 ATP-binding cassette, sub-family A member 2 involved_in IMP (PMID:17488728) UniProt PMID:17488728 NCBI chr 2:25,318,611...25,338,556
Ensembl chr 2:25,318,715...25,338,552
JBrowse link
G Cln6 ceroid-lipofuscinosis, neuronal 6 involved_in ISO GO_Central GO_REF:0000119 NCBI chr 9:62,746,067...62,759,288
Ensembl chr 9:62,746,067...62,759,288
JBrowse link
G Gm2a GM2 ganglioside activator protein involved_in ISO RGD
GO_Central
PMID:9770472 GO_REF:0000096 RGD:1598995 NCBI chr11:54,988,811...55,003,855
Ensembl chr11:54,988,941...55,003,855
JBrowse link
G Itgb8 integrin beta 8 acts_upstream_of_or_within IMP (PMID:16251442) MGI PMID:16251442 NCBI chr12:119,121,757...119,202,891
Ensembl chr12:119,121,757...119,202,537
JBrowse link
G Naglu alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB) acts_upstream_of_or_within IMP (PMID:21408219) MGI PMID:21408219 NCBI chr11:100,960,918...100,968,483
Ensembl chr11:100,960,838...100,968,498
JBrowse link
ganglioside biosynthetic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G B3galt4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr17:34,168,886...34,170,462
Ensembl chr17:34,168,883...34,170,462
JBrowse link
G B4galnt1 beta-1,4-N-acetyl-galactosaminyl transferase 1 acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
ISS
IGI
(PMID:10021458)
(PMID:8855236)
MGI
GO_Central
UniProt
PMID:8855236 PMID:10021458 GO_REF:0000024 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 NCBI chr10:127,001,025...127,008,209
Ensembl chr10:127,001,094...127,008,199
JBrowse link
G St6galnac1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 acts_upstream_of_or_within TAS (PMID:10788794) MGI PMID:10788794 NCBI chr11:116,655,851...116,666,333
Ensembl chr11:116,655,851...116,666,333
JBrowse link
G St6galnac3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:152,903,911...153,430,804
Ensembl chr 3:152,903,903...153,430,811
JBrowse link
G St6galnac4 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:32,477,100...32,489,710
Ensembl chr 2:32,477,107...32,489,710
JBrowse link
G St6galnac5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 involved_in IBA GO_Central GO_REF:0000033 NCBI chr 3:152,525,522...152,687,847
Ensembl chr 3:152,522,718...152,687,883
JBrowse link
G St6galnac6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6 involved_in
acts_upstream_of_or_within
IBA
IDA
(PMID:10702226) GO_Central
MGI
PMID:10702226 GO_REF:0000033 NCBI chr 2:32,489,721...32,510,821
Ensembl chr 2:32,489,721...32,510,818
JBrowse link
G St8sia2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2 involved_in ISO
IEA
GO_Central
Ensembl
GO_REF:0000107 GO_REF:0000119 NCBI chr 7:73,588,867...73,663,408
Ensembl chr 7:73,588,867...73,663,438
JBrowse link
G St8sia3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 involved_in ISO
IDA
(PMID:7782326) GO_Central
UniProt
PMID:7782326 GO_REF:0000119 NCBI chr18:64,387,430...64,409,217
Ensembl chr18:64,387,430...64,412,682
JBrowse link
G St8sia4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 involved_in IEA
ISO
Ensembl
GO_Central
GO_REF:0000107 GO_REF:0000119 NCBI chr 1:95,515,407...95,595,473
Ensembl chr 1:95,515,407...95,595,296
JBrowse link
G St8sia6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 involved_in IDA (PMID:11980897) BHF-UCL PMID:11980897 NCBI chr 2:13,659,745...13,798,659
Ensembl chr 2:13,655,832...13,798,875
JBrowse link
ganglioside biosynthetic process via lactosylceramide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G 6430550D23Rik RIKEN cDNA 6430550D23 gene involved_in IBA GO_Central GO_REF:0000033 NCBI chr 2:155,831,465...155,850,315
Ensembl chr 2:155,815,199...155,849,897
JBrowse link
G B4galt5 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5 involved_in IMP (PMID:30114188) UniProt PMID:30114188 NCBI chr 2:167,140,364...167,191,155
Ensembl chr 2:167,140,364...167,191,103
JBrowse link
G B4galt6 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 involved_in IMP (PMID:30114188) UniProt PMID:30114188 NCBI chr18:20,817,656...20,879,461
Ensembl chr18:20,817,656...20,879,461
JBrowse link
G St3gal1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 involved_in IDA
IBA
ISO
(PMID:8144500) UniProt
GO_Central
PMID:8144500 GO_REF:0000033 GO_REF:0000119 NCBI chr15:66,974,724...67,048,575
Ensembl chr15:66,974,724...67,048,679
JBrowse link
G St3gal2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2 involved_in IMP
IBA
ISO
IDA
(PMID:22735313)
(PMID:8144500)
UniProt
GO_Central
PMID:8144500 PMID:22735313 GO_REF:0000033 GO_REF:0000096 GO_REF:0000119 NCBI chr 8:111,646,520...111,699,132
Ensembl chr 8:111,646,554...111,699,112
JBrowse link
G St3gal3 ST3 beta-galactoside alpha-2,3-sialyltransferase 3 involved_in IMP (PMID:22735313) UniProt PMID:22735313 NCBI chr 4:117,789,349...117,992,169
Ensembl chr 4:117,789,351...117,992,111
JBrowse link
ganglioside catabolic process term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Glb1 galactosidase, beta 1 involved_in IMP (PMID:31720227) FlyBase PMID:31720227 NCBI chr 9:114,230,146...114,303,447
Ensembl chr 9:114,230,144...114,303,966
JBrowse link
G Gm2a GM2 ganglioside activator protein involved_in
acts_upstream_of_or_within
IBA
IMP
(PMID:9223328) GO_Central
MGI
PMID:9223328 GO_REF:0000033 NCBI chr11:54,988,811...55,003,855
Ensembl chr11:54,988,941...55,003,855
JBrowse link
G Hexa hexosaminidase A acts_upstream_of_or_within
involved_in
IMP
IBA
ISO
ISS
(PMID:7937929), (PMID:9223328)
(PMID:8789434), (PMID:9645704)
MGI
GO_Central
UniProt
PMID:7937929 PMID:8789434 PMID:9223328 PMID:9645704 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 9:59,446,966...59,472,392
Ensembl chr 9:59,446,823...59,472,392
JBrowse link
G Hexb hexosaminidase B acts_upstream_of_or_within
involved_in
IMP
IBA
ISS
ISO
(PMID:10021458), (PMID:12657883), (PMID:12756243), (PMID:15748167), (PMID:9223328)
(PMID:8566348)
(PMID:8789434), (PMID:9645704)
MGI
GO_Central
UniProt
PMID:8566348 PMID:8789434 PMID:9223328 PMID:9645704 PMID:10021458 More... GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr13:97,312,839...97,334,865
Ensembl chr13:97,312,839...97,334,865
JBrowse link
G Neu1 neuraminidase 1 involved_in IBA GO_Central GO_REF:0000033 NCBI chr17:35,150,229...35,156,273
Ensembl chr17:35,150,229...35,154,929
JBrowse link
G Neu2 neuraminidase 2 involved_in ISO
IBA
IDA
ISS
(PMID:10713120) GO_Central
UniProt
PMID:10713120 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:87,501,749...87,525,567
Ensembl chr 1:87,437,611...87,525,567
JBrowse link
G Neu3 neuraminidase 3 involved_in IDA
IBA
ISS
ISO
(PMID:11696012), (PMID:14970224), (PMID:17708748) UniProt
GO_Central
PMID:11696012 PMID:14970224 PMID:17708748 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 7:99,460,646...99,477,579
Ensembl chr 7:99,460,646...99,477,624
JBrowse link
G Neu4 sialidase 4 involved_in ISS
IBA
IDA
ISO
(PMID:19506080) UniProt
GO_Central
PMID:19506080 GO_REF:0000024 GO_REF:0000033 GO_REF:0000119 NCBI chr 1:93,948,215...93,956,056
Ensembl chr 1:93,948,173...93,956,056
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      metabolic process 11662
        amide metabolic process 505
          ceramide metabolic process 110
            ganglioside metabolic process 29
              ganglioside biosynthetic process + 17
              ganglioside catabolic process 8
Path 2
Term Annotations click to browse term
  biological_process 28635
    cellular process 18389
      metabolic process 11662
        primary metabolic process 10275
          lipid metabolic process 1510
            membrane lipid metabolic process 207
              sphingolipid metabolic process 157
                ceramide metabolic process 110
                  ganglioside metabolic process 29
                    ganglioside biosynthetic process + 17
                    ganglioside catabolic process 8
paths to the root