Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hexa (hexosaminidase A) Mus musculus
Symbol: Hexa
Name: hexosaminidase A
RGD ID: 10707
Description: Exhibits beta-N-acetylhexosaminidase activity. Involved in several processes, including SMAD protein signal transduction; adult walking behavior; and nervous system development. Localizes to lysosome and membrane. Is expressed in brain; mandible; and maxilla. Used to study Tay-Sachs disease. Human ortholog(s) of this gene implicated in Tay-Sachs disease. Orthologous to human HEXA (hexosaminidase subunit alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: beta-hexosaminidase subunit alpha; beta-N-acetylhexosaminidase subunit alpha; Hex-1; hexosaminidase subunit A; N-acetyl-beta-glucosaminidase subunit alpha
Homo sapiens (human) : HEXA (hexosaminidase subunit alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hexa (hexosaminidase subunit alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hexa (hexosaminidase subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : LOC100986229 (CUGBP Elav-like family member 6)
Canis lupus familiaris (dog) : HEXA (hexosaminidase subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hexa (hexosaminidase subunit alpha)
Sus scrofa (pig) : HEXA (hexosaminidase subunit alpha)
Chlorocebus sabaeus (African green monkey) : HEXA (hexosaminidase subunit alpha)
Heterocephalus glaber (naked mole-rat) : Hexa (hexosaminidase subunit alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl959,539,540 - 59,565,109 (+)EnsemblGRCm38mm10GRCm38
GRCm38959,539,540 - 59,565,109 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37959,387,474 - 59,412,912 (+)NCBIGRCm37mm9NCBIm37
MGSCv36959,337,673 - 59,363,111 (+)NCBImm8
Celera956,766,853 - 56,792,230 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map932.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hexa
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10707
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.