Hexb (hexosaminidase B) - Rat Genome Database

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Gene: Hexb (hexosaminidase B) Mus musculus
Analyze
Symbol: Hexb
Name: hexosaminidase B
RGD ID: 1316899
MGI Page MGI
Description: Enables beta-N-acetylhexosaminidase activity and identical protein binding activity. Involved in several processes, including astrocyte cell migration; positive regulation of transcription by RNA polymerase II; and regulation of cell shape. Acts upstream of or within several processes, including ganglioside catabolic process; male courtship behavior; and penetration of zona pellucida. Located in several cellular components, including extracellular space; lysosome; and secretory granule. Is expressed in several structures, including endocrine gland; eye; genitourinary system; nervous system; and sternum. Used to study Sandhoff disease. Human ortholog(s) of this gene implicated in Sandhoff disease and spinal muscular atrophy. Orthologous to human HEXB (hexosaminidase subunit beta); PARTICIPATES IN amino sugar metabolic pathway; ganglioside metabolic pathway; globoside metabolic pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-(ethoxymethylene)-2-phenyloxazol-5-one.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: beta-hexosaminidase subunit beta; beta-N-acetylhexosaminidase subunit beta; hexosaminidase subunit B; N-acetyl-beta-glucosaminidase subunit beta
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,312,839 - 97,334,865 (-)NCBIGRCm39mm39
GRCm39 Ensembl1397,312,839 - 97,334,865 (-)Ensembl
GRCm381397,176,331 - 97,198,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,176,331 - 97,198,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,946,286 - 97,968,312 (-)NCBIGRCm37mm9NCBIm37
MGSCv361398,277,106 - 98,298,969 (-)NCBImm8
Celera13100,809,364 - 100,830,755 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,6-di-tert-butyl-4-methylphenol  (ISO)
2,6-dinitrotoluene  (ISO)
2-hydroxypropanoic acid  (ISO)
2-Methylaziridine  (ISO)
3-chloropropane-1,2-diol  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
5-aza-2'-deoxycytidine  (ISO)
acrolein  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ampicillin  (ISO)
Aroclor 1254  (EXP)
astemizole  (ISO)
atracurium  (ISO)
atrazine  (ISO)
azithromycin  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (EXP,ISO)
biphenyl-2-ol  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bitertanol  (ISO)
Brodifacoum  (ISO)
buspirone  (ISO)
butylated hydroxyanisole  (ISO)
Butylparaben  (ISO)
cadmium atom  (ISO)
carbamazepine  (ISO)
carbon nanotube  (EXP)
cetirizine  (ISO)
chlordecone  (EXP)
choline  (EXP)
chromium(6+)  (EXP)
cisplatin  (ISO)
clofibric acid  (ISO)
cupressuflavone  (EXP)
cyclosporin A  (ISO)
Deguelin  (ISO)
dexamethasone  (ISO)
dextromethorphan  (ISO)
dicrotophos  (ISO)
doxorubicin  (ISO)
enniatin  (ISO)
entinostat  (ISO)
ethanol  (EXP)
finasteride  (ISO)
flunarizine  (ISO)
flutamide  (ISO)
folic acid  (EXP)
furan  (ISO)
gamma-linolenic acid  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glyphosate  (ISO)
hydroxyzine  (ISO)
indometacin  (ISO)
ionomycin  (ISO)
ivermectin  (ISO)
KN-93  (ISO)
L-methionine  (EXP)
lead diacetate  (EXP)
lipopolysaccharide  (EXP)
metronidazole  (ISO)
Mibefradil  (ISO)
ML-7  (ISO)
N,N-diethyl-m-toluamide  (ISO)
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
neomycin  (ISO)
nickel dichloride  (ISO)
Oxatomide  (ISO)
oxycodone  (ISO)
ozone  (ISO)
paracetamol  (ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenobarbital  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (EXP)
prothiofos  (ISO)
pyridaben  (ISO)
pyrimethamine  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (ISO)
rotenone  (ISO)
Salinomycin  (ISO)
silver atom  (EXP)
silver(0)  (EXP)
sodium fluoride  (EXP)
Soman  (ISO)
sunitinib  (ISO)
terbufos  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (EXP)
titanium dioxide  (EXP)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vecuronium bromide  (ISO)
Yessotoxin  (ISO)
zinc dichloride  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal axial skeleton morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal CNS glial cell morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal digit morphology  (IAGP)
abnormal efferent ductules of testis morphology  (IAGP)
abnormal epididymis morphology  (IAGP)
abnormal eye morphology  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal gait  (IAGP)
abnormal hepatocyte morphology  (IAGP)
abnormal lipid homeostasis  (IAGP)
abnormal lipid level  (IAGP)
abnormal liver morphology  (IAGP)
abnormal locomotor behavior  (IEA)
abnormal lysosome morphology  (IAGP)
abnormal macrophage morphology  (IAGP)
abnormal mandible morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal myelination  (IAGP)
abnormal nervous system morphology  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal posture  (IAGP)
abnormal proximal convoluted tubule morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal renal tubule epithelium morphology  (IAGP)
abnormal rib morphology  (IAGP)
abnormal righting response  (IAGP)
abnormal seizure response to electrical stimulation  (IAGP)
abnormal sexual interaction  (IAGP)
abnormal spinal cord interneuron morphology  (IAGP)
abnormal spinal cord morphology  (IAGP)
abnormal thoracic cage shape  (IAGP)
abnormal trabecular bone morphology  (IAGP)
abnormal tumor necrosis factor level  (IAGP)
abnormal urine homeostasis  (IAGP)
abnormal vacuole morphology  (IAGP)
abnormal vertebrae morphology  (IAGP)
ataxia  (IAGP)
bradykinesia  (IAGP)
broad snout  (IAGP)
camptodactyly  (IAGP)
CNS inflammation  (IAGP)
corneal opacity  (IAGP)
deafness  (IAGP)
decreased apoptosis  (IAGP)
decreased circulating fructosamine level  (IEA)
decreased length of long bones  (IAGP)
decreased total body fat amount  (IAGP)
decreased vertical activity  (IAGP)
enlarged caput epididymis  (IAGP)
enlarged corpus epididymis  (IAGP)
frontal bossing  (IAGP)
hindlimb paralysis  (IAGP)
hypoactivity  (IAGP)
impaired coordination  (IAGP)
impaired fertilization  (IAGP)
impaired limb coordination  (IAGP)
impaired righting response  (IAGP)
increased circulating alkaline phosphatase level  (IEA)
increased circulating aspartate transaminase level  (IEA)
increased circulating interleukin-4 level  (IAGP)
increased diameter of long bones  (IAGP)
increased epididymis weight  (IAGP)
increased forebrain apoptosis  (IAGP)
increased immunoglobulin level  (IAGP)
increased monocyte cell number  (IEA)
increased urine glycosaminoglycan level  (IAGP)
infertility  (IAGP)
kyphosis  (IAGP)
lethargy  (IAGP)
limb grasping  (IAGP)
microgliosis  (IAGP)
muscle hypertonia  (IAGP)
muscle weakness  (IAGP)
muscular atrophy  (IAGP)
neurodegeneration  (IAGP)
postnatal growth retardation  (IAGP)
premature death  (IAGP)
Purkinje cell degeneration  (IAGP)
seminiferous tubule degeneration  (IAGP)
shortened head  (IAGP)
sporadic seizures  (IAGP)
thrombocytosis  (IEA)
tremors  (IAGP)
weight loss  (IAGP)
wide ribs  (IAGP)
References

Additional References at PubMed
PMID:1054503   PMID:1535334   PMID:2307475   PMID:2947337   PMID:2971567   PMID:7203014   PMID:7550345   PMID:7918686   PMID:7959736   PMID:8147878   PMID:8253842   PMID:8269854  
PMID:8566348   PMID:8634145   PMID:8678993   PMID:8789434   PMID:8828042   PMID:8889548   PMID:8896570   PMID:9119362   PMID:9122231   PMID:9184660   PMID:9223328   PMID:9237263  
PMID:9302266   PMID:9417048   PMID:9562524   PMID:9576752   PMID:9584189   PMID:9645704   PMID:9728335   PMID:10021458   PMID:10339597   PMID:10349636   PMID:10591618   PMID:10922068  
PMID:11005868   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11707436   PMID:11849560   PMID:11854359   PMID:11919180   PMID:12466851   PMID:12617783   PMID:12657883   PMID:12756243  
PMID:12887594   PMID:12904583   PMID:14610273   PMID:14681479   PMID:14691112   PMID:14722612   PMID:15155903   PMID:15198669   PMID:15748167   PMID:15782199   PMID:16123447   PMID:16141072  
PMID:16141073   PMID:16441513   PMID:16456008   PMID:16888648   PMID:16982810   PMID:17372214   PMID:17442056   PMID:17883393   PMID:18180457   PMID:18424450   PMID:18550711   PMID:18611415  
PMID:18657867   PMID:18799693   PMID:19026003   PMID:19033672   PMID:19166507   PMID:19463158   PMID:19637231   PMID:19710420   PMID:19865483   PMID:20374428   PMID:20616152   PMID:20856892  
PMID:20864542   PMID:21151498   PMID:21267068   PMID:21598013   PMID:21852247   PMID:21873635   PMID:22451654   PMID:22496568   PMID:23028353   PMID:23383290   PMID:23727835   PMID:24057669  
PMID:24194600   PMID:24441827   PMID:25015817   PMID:25795792   PMID:26467605   PMID:26545928   PMID:26681805   PMID:27018595   PMID:27453479   PMID:27534441   PMID:27605553   PMID:28007910  
PMID:28084424   PMID:28377426   PMID:28575132   PMID:28728022   PMID:29325092   PMID:29514215   PMID:29900534   PMID:30026035   PMID:30550785   PMID:31340161   PMID:31547903   PMID:31999726  
PMID:32325033   PMID:32541832   PMID:33219123   PMID:33887203  


Genomics

Comparative Map Data
Hexb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391397,312,839 - 97,334,865 (-)NCBIGRCm39mm39
GRCm39 Ensembl1397,312,839 - 97,334,865 (-)Ensembl
GRCm381397,176,331 - 97,198,357 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1397,176,331 - 97,198,357 (-)EnsemblGRCm38mm10GRCm38
MGSCv371397,946,286 - 97,968,312 (-)NCBIGRCm37mm9NCBIm37
MGSCv361398,277,106 - 98,298,969 (-)NCBImm8
Celera13100,809,364 - 100,830,755 (-)NCBICelera
Cytogenetic Map13D1NCBI
cM Map1350.66NCBI
HEXB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl574,640,023 - 74,722,647 (+)EnsemblGRCh38hg38GRCh38
GRCh38574,640,023 - 74,721,288 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37573,935,848 - 74,017,113 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36574,016,767 - 74,052,869 (+)NCBINCBI36hg18NCBI36
Build 34574,016,766 - 74,052,869NCBI
Celera569,875,759 - 69,911,869 (+)NCBI
Cytogenetic Map5q13.3NCBI
HuRef569,185,979 - 69,222,054 (+)NCBIHuRef
CHM1_1573,413,670 - 73,449,974 (+)NCBICHM1_1
Hexb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2228,483,997 - 28,504,165 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl228,484,012 - 28,504,223 (-)Ensembl
Rnor_6.0227,983,925 - 28,003,260 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl227,984,117 - 28,003,186 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0247,094,814 - 47,114,992 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4227,649,188 - 27,672,231 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1227,569,557 - 27,592,600 (-)NCBI
Celera224,525,921 - 24,545,955 (-)NCBICelera
Cytogenetic Map2q12NCBI
Hexb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542525,942,278 - 25,961,312 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542525,942,341 - 25,961,312 (-)NCBIChiLan1.0ChiLan1.0
HEXB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1541,199,681 - 41,232,693 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl541,199,681 - 41,232,693 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0540,589,448 - 40,625,176 (-)NCBIMhudiblu_PPA_v0panPan3
HEXB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1257,221,809 - 57,248,432 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl257,222,186 - 57,248,417 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha254,199,623 - 54,228,736 (+)NCBI
ROS_Cfam_1.0257,746,022 - 57,775,171 (+)NCBI
UMICH_Zoey_3.1254,810,104 - 54,839,238 (+)NCBI
UNSW_CanFamBas_1.0255,573,246 - 55,602,349 (+)NCBI
UU_Cfam_GSD_1.0256,470,393 - 56,499,556 (+)NCBI
Hexb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213188,915,295 - 188,940,491 (+)NCBI
SpeTri2.0NW_0049365491,918,482 - 1,943,665 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HEXB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl283,744,627 - 83,784,759 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1283,745,263 - 83,784,762 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2285,331,866 - 85,371,568 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HEXB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1469,037,532 - 69,065,925 (+)NCBI
ChlSab1.1 Ensembl469,037,583 - 69,065,814 (+)Ensembl
Vero_WHO_p1.0NW_02366604917,815,486 - 17,843,814 (+)NCBI
Hexb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624924195,406 - 219,232 (-)NCBI

Position Markers
Y00964  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381397,176,409 - 97,176,520UniSTSGRCm38
MGSCv371397,946,364 - 97,946,475UniSTSGRCm37
Celera13100,809,442 - 100,809,553UniSTS
Cytogenetic Map13D1UniSTS
cM Map1346.0UniSTS
Whitehead/MRC_RH13831.54UniSTS
Hexb  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map13D1UniSTS
cM Map1346.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142147Mvwf4_mmodifier of von Willebrand factor 4 (mouse)Not determined20293442112761890Mouse
4142241Tailq3_mtail length QTL 3 (mouse)Not determined55572541112294569Mouse
4141992W6q16_mweight 6 weeks QTL 16 (mouse)Not determined55572541112294569Mouse
4142314Tailaq3_mtail length adjusted QTL 3 (mouse)Not determined55572541112294569Mouse
4140959W10q17_mweight 10 weeks QTL 17 (mouse)Not determined55572541112294569Mouse
10402414Sgp5_mserum gp70 production 5 (mouse)Not determined1356322643105285678Mouse
1300941Skl6_mskeletal size (tail length) 6 (mouse)Not determined136410270298102826Mouse
1301949Skull20_mskull morphology 20 (mouse)Not determined136410270298102826Mouse
1301445Listr2_mlisteriosis resistance 2 (mouse)Not determined1366596482100596627Mouse
1301593Heal8_mwound healing/regeneration 8 (mouse)Not determined1367905880101906000Mouse
14696726Kidrq3_mkidney weight, right QTL 3 (mouse)1368068947102068947Mouse
14747007Mancz11_mmandible centroid size 11 (mouse)1369963165103963165Mouse
4141266Mol3_mmodifier of LPS-response 3 (mouse)Not determined75984481112294569Mouse
12880414V125Dq10_mvitamin D active form serum level QTL 10 (mouse)1377900000111900000Mouse
10045623Heal18_mwound healing regeneration 18 (mouse)Not determined1379102537113102654Mouse
1558741Ses10_msalmonella enteritidis susceptibility 10 (mouse)Not determined1382603460116603598Mouse
4142465Pbwg17_mpostnatal body weight growth 17 (mouse)Not determined1383739552117739748Mouse
14700691Cisaq1_mcoxsackieviral infection serum ALT QTL 1 (mouse)1386000000120000000Mouse
4140995Fbtq6_mfemoral bone trait QTL 6 (mouse)Not determined1386205109120205250Mouse
4141728Egaq4_mearly growth adjusted QTL 4 (mouse)Not determined87753866112294569Mouse
1300939Hrtfm6_mheart failure modifier 6 (mouse)Not determined1391247158120421639Mouse
1300876Tanidd2_mtally ho associated non-insulin dependednt diabetes mellitus 2 (mouse)Not determined1391828769120421639Mouse
1301142Heal2_mwound healing/regeneration 2 (mouse)Not determined1393738733120421639Mouse
4142338Skmw18_mskeletal muscle weight 18 (mouse)Not determined1394391865120421639Mouse
1558763Gct9_mgranulosa cell tumorigenesis 9 (mouse)Not determined1394900290120421639Mouse
1357468Rplag_mreduced platelet aggregation (mouse)Not determined1395365596120421639Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:55
Interacting mature miRNAs:58
Transcripts:ENSMUST00000022169
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC154620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC160109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151149 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK160560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185127 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194154 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212361 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY145642 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD775639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U07633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  Y00964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000022169   ⟹   ENSMUSP00000022169
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1397,312,839 - 97,334,865 (-)Ensembl
GRCm38.p6 Ensembl1397,176,331 - 97,198,357 (-)Ensembl
RefSeq Acc Id: ENSMUST00000222700
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1397,320,184 - 97,334,803 (-)Ensembl
GRCm38.p6 Ensembl1397,183,676 - 97,198,295 (-)Ensembl
RefSeq Acc Id: NM_010422   ⟹   NP_034552
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391397,312,839 - 97,334,865 (-)NCBI
GRCm381397,176,331 - 97,198,357 (-)ENTREZGENE
MGSCv371397,946,286 - 97,968,312 (-)RGD
Celera13100,809,364 - 100,830,755 (-)RGD
cM Map13 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034552   ⟸   NM_010422
- Peptide Label: precursor
- UniProtKB: P20060 (UniProtKB/Swiss-Prot),   Q3TXR9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000022169   ⟸   ENSMUST00000022169
Protein Domains
Glyco_hydro_20   Glycohydro_20b2

Promoters
RGD ID:8681092
Promoter ID:EPDNEW_M18577
Type:initiation region
Name:Hexb_1
Description:Mus musculus hexosaminidase B , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381397,198,330 - 97,198,390EPDNEW
RGD ID:6849021
Promoter ID:MM_XEF:1999
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:ES_Cell
Transcripts:NM_001126987,   NM_001127137
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361397,960,581 - 97,961,081 (-)MPROMDB
RGD ID:6824009
Promoter ID:MM_KWN:14991
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_010422
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361397,968,009 - 97,968,509 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96074 AgrOrtholog
Ensembl Genes ENSMUSG00000021665 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000022169 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000022169 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.379.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Beta_hexosaminidase_sua/sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glyco_hydro_20_cat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycoside_hydrolase_SF UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hex-like_dom2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HEX_eukaryotic_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15212 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96074 ENTREZGENE
NCBI Gene 15212 ENTREZGENE
Pfam Glyco_hydro_20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycohydro_20b2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Hexb PhenoGen
PIRSF B-hxosamndse_ab_euk UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
PRINTS GLHYDRLASE20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51445 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF55545 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt HEXB_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TXR9 ENTREZGENE, UniProtKB/TrEMBL