St6galnac5 (ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) - Rat Genome Database

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Gene: St6galnac5 (ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5) Mus musculus
Analyze
Symbol: St6galnac5
Name: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
RGD ID: 1557501
MGI Page MGI
Description: Enables alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity. Involved in glycosphingolipid biosynthetic process and oligosaccharide biosynthetic process. Predicted to be located in Golgi apparatus and membrane. Is expressed in several structures, including alimentary system; genitourinary system; heart; nervous system; and respiratory system. Orthologous to human ST6GALNAC5 (ST6 N-acetylgalactosaminide alpha-2,6-sialyltransferase 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI851940; alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5; galNAc alpha-2,6-sialyltransferase V; GD1 alpha synthase; Sia; sialyltransferase 7 ((alpha-N-acetylneuraminyl 2,3-betagalactosyl-1,3)-N-acetyl galactosaminide alpha-2,6-sialyltransferase) E; sialyltransferase 7E; SIAT7-E; Siat7e; ST6GalNAc V; ST6GalNAcV
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393152,525,522 - 152,687,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3152,522,718 - 152,687,883 (-)EnsemblGRCm39 Ensembl
GRCm383152,819,885 - 152,982,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3152,817,081 - 152,982,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv373152,483,673 - 152,645,171 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363152,757,272 - 152,919,596 (-)NCBIMGSCv36mm8
Celera3159,273,952 - 159,435,518 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map377.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MGDs mouse GO annotations MGD data from the GO Consortium
2. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Database resources of the National Center for Biotechnology Information. Wheeler DL, etal., Nucleic Acids Res 2001 Jan 1;29(1):11-6.
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10521438   PMID:10601645   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12477932   PMID:12668675   PMID:14681479   PMID:16141072   PMID:16141073  
PMID:16602821   PMID:21267068   PMID:21677750   PMID:21873635   PMID:28942923  


Genomics

Comparative Map Data
St6galnac5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393152,525,522 - 152,687,847 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3152,522,718 - 152,687,883 (-)EnsemblGRCm39 Ensembl
GRCm383152,819,885 - 152,982,210 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3152,817,081 - 152,982,246 (-)EnsemblGRCm38mm10GRCm38
MGSCv373152,483,673 - 152,645,171 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363152,757,272 - 152,919,596 (-)NCBIMGSCv36mm8
Celera3159,273,952 - 159,435,518 (-)NCBICelera
Cytogenetic Map3H3NCBI
cM Map377.16NCBI
ST6GALNAC5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38176,867,480 - 77,067,546 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl176,867,480 - 77,067,546 (+)EnsemblGRCh38hg38GRCh38
GRCh37177,333,165 - 77,533,231 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36177,105,774 - 77,302,325 (+)NCBINCBI36Build 36hg18NCBI36
Build 34177,045,206 - 77,241,756NCBI
Celera175,572,629 - 75,769,169 (+)NCBICelera
Cytogenetic Map1p31.1NCBI
HuRef175,463,113 - 75,660,214 (+)NCBIHuRef
CHM1_1177,448,510 - 77,645,048 (+)NCBICHM1_1
T2T-CHM13v2.0176,705,077 - 76,905,729 (+)NCBIT2T-CHM13v2.0
St6galnac5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82244,398,604 - 244,571,100 (-)NCBIGRCr8
mRatBN7.22241,741,933 - 241,911,214 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2241,742,688 - 241,911,208 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2249,554,339 - 249,722,560 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02247,441,354 - 247,609,586 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02242,354,046 - 242,521,845 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02258,025,177 - 259,150,709 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2258,025,177 - 258,052,835 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02276,689,490 - 276,717,145 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.02277,817,171 - 277,818,389 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera2233,679,302 - 233,847,270 (-)NCBICelera
Cytogenetic Map2q45NCBI
ST6GALNAC5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21149,826,258 - 150,027,714 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11148,984,098 - 149,188,156 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0176,080,706 - 76,284,836 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1178,167,466 - 78,370,516 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl178,167,280 - 78,366,180 (+)Ensemblpanpan1.1panPan2
ST6GALNAC5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1669,706,717 - 69,867,760 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl669,709,114 - 69,867,648 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha672,366,015 - 72,525,097 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0670,295,425 - 70,454,897 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl670,296,050 - 70,455,316 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1669,798,107 - 69,957,045 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0669,744,317 - 69,903,731 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0670,230,805 - 70,390,076 (-)NCBIUU_Cfam_GSD_1.0
St6galnac5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505888,305,513 - 88,462,943 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365713,815,823 - 3,973,328 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365713,815,867 - 3,971,219 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST6GALNAC5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6136,204,374 - 136,390,995 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16136,207,838 - 136,391,083 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26126,450,055 - 126,451,320 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ST6GALNAC5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12056,110,411 - 56,299,639 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2056,113,473 - 56,131,866 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603361,222,546 - 61,409,715 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St6galnac5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474220,023,494 - 20,188,072 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474220,021,252 - 20,188,542 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in St6galnac5
5502 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1499
Count of miRNA genes:724
Interacting mature miRNAs:904
Transcripts:ENSMUST00000044278, ENSMUST00000161757
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse
1301222Scc7_mcolon tumor susceptibility 7 (mouse)Not determined3143352986156364108Mouse
10045615Hrtfm8_mheart failure modifier 8 (mouse)Not determined3148451045152592311Mouse

Markers in Region
AI851940  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383152,820,826 - 152,820,960UniSTSGRCm38
MGSCv373152,483,790 - 152,483,924UniSTSGRCm37
Celera3159,274,069 - 159,274,203UniSTS
Cytogenetic Map3H3UniSTS
Whitehead/MRC_RH31677.97UniSTS
18.MMHAP61FRF9.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383152,852,564 - 152,852,716UniSTSGRCm38
MGSCv373152,515,528 - 152,515,680UniSTSGRCm37
Celera3159,305,678 - 159,305,830UniSTS
Cytogenetic Map3H3UniSTS
Whitehead_YAC3 UniSTS
D3Mit322  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383152,886,552 - 152,886,674UniSTSGRCm38
MGSCv373152,549,516 - 152,549,638UniSTSGRCm37
Celera3159,339,709 - 159,339,834UniSTS
Cytogenetic Map3H3UniSTS
cM Map383.5UniSTS
Whitehead Genetic363.4UniSTS
Whitehead_YAC3 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000044278   ⟹   ENSMUSP00000036227
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3152,522,718 - 152,687,883 (-)Ensembl
GRCm38.p6 Ensembl3152,817,081 - 152,982,246 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161757
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3152,681,011 - 152,687,689 (-)Ensembl
GRCm38.p6 Ensembl3152,975,374 - 152,982,052 (-)Ensembl
RefSeq Acc Id: NM_012028   ⟹   NP_036158
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393152,525,522 - 152,687,847 (-)NCBI
GRCm383152,819,885 - 152,982,210 (-)NCBI
MGSCv373152,483,673 - 152,645,171 (-)RGD
Celera3159,273,952 - 159,435,518 (-)RGD
cM Map3 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_036158   ⟸   NM_012028
- UniProtKB: Q9R0K6 (UniProtKB/Swiss-Prot),   Q9QYJ1 (UniProtKB/Swiss-Prot),   Q6GTI0 (UniProtKB/TrEMBL),   Q8CAM7 (UniProtKB/TrEMBL),   Q8CBX1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000036227   ⟸   ENSMUST00000044278

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QYJ1-F1-model_v2 AlphaFold Q9QYJ1 1-336 view protein structure

Promoters
RGD ID:6849148
Promoter ID:MM_XEF:4837
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Spleen
Transcripts:NM_001006662,   NM_001172277,   NM_001174173
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363152,509,214 - 152,509,714 (-)MPROMDB
RGD ID:6849143
Promoter ID:MM_XEF:4838
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:NM_001037308
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363152,643,994 - 152,644,494 (-)MPROMDB
RGD ID:6882660
Promoter ID:EPDNEW_M4781
Type:multiple initiation site
Name:St6galnac5_1
Description:Mus musculus ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383152,982,210 - 152,982,270EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349471 AgrOrtholog
Ensembl Genes ENSMUSG00000039037 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000044278 ENTREZGENE
  ENSMUST00000044278.6 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26938 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1349471 ENTREZGENE
NCBI Gene 26938 ENTREZGENE
PANTHER ALPHA-N-ACETYLGALACTOSAMINIDE ALPHA-2,6-SIALYLTRANSFERASE 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR45906 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen St6galnac5 PhenoGen
PIRSF Sialyl_trans UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt Q6GTI0 ENTREZGENE, UniProtKB/TrEMBL
  Q8CAM7 ENTREZGENE, UniProtKB/TrEMBL
  Q8CBX1 ENTREZGENE, UniProtKB/TrEMBL
  Q9QYJ1 ENTREZGENE
  Q9R0K6 ENTREZGENE
  SIA7E_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q9R0K6 UniProtKB/Swiss-Prot