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ONTOLOGY REPORT - ANNOTATIONS

Term:spliceosomal tri-snRNP complex assembly
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Accession:GO:0000244 term browser browse the term
Definition:The formation of a tri-snRNP complex containing U4 and U6 (or U4atac and U6atac) snRNAs and U5 snRNAs and associated proteins. This includes reannealing of U4 and U6 (or U4atac and U6atac) snRNAs released from previous rounds of splicing to reform the U4/U6 snRNP (or U4atac/U6atac snRNP) as well as the subsequent association of the U5 snRNP with the U4/U6 snRNP (or U4atac/U6atac snRNP) to form a tri-snRNP that is ready to reassemble into another spliceosome complex.
Synonyms:exact_synonym: assembly of spliceosomal tri-snRNP;   spliceosomal tri-snRNP assembly
 narrow_synonym: assembly of spliceosomal tri-snRNP U4/U6.U5;   assembly of spliceosomal tri-snRNP U4atac/U6atac.U5;   spliceosomal tri-snRNP U4/U6.U5 assembly;   spliceosomal tri-snRNP U4atac/U6atac.U5 assembly
 broad_synonym: snRNP recycling
 alt_id: GO:0000351;   GO:0000355

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spliceosomal tri-snRNP complex assembly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lsm2 LSM2 homolog, U6 small nuclear RNA and mRNA degradation associated acts_upstream_of_or_within ISO (PMID:10523320) MGI PMID:10523320 NCBI chrNW_004955437:321,367...325,556
Ensembl chrNW_004955437:320,768...325,810 		JBrowse link
G Prp4k pre-mRNA processing factor kinase PRP4K involved_in ISO (PMID:20118938) UniProt PMID:20118938 NCBI chrNW_004955465:9,359,634...9,392,913
Ensembl chrNW_004955465:9,359,634...9,392,913 		JBrowse link
G Prpf19 pre-mRNA processing factor 19 involved_in ISO (PMID:20595234) UniProt PMID:20595234 NCBI chrNW_004955511:5,546,212...5,552,368
Ensembl chrNW_004955511:5,545,989...5,557,792 		JBrowse link
G Prpf3 pre-mRNA processing factor 3 involved_in ISO (PMID:20595234) UniProt PMID:20595234 NCBI chrNW_004955413:429,259...455,449
Ensembl chrNW_004955413:429,259...455,463 		JBrowse link
G Prpf31 pre-mRNA processing factor 31 involved_in
acts_upstream_of_or_within		 ISO (PMID:15257298)
(PMID:20118938)
(PMID:11867543)		 BHF-UCL
UniProt
MGI		 PMID:11867543 PMID:15257298 PMID:20118938 NCBI chrNW_004955604:125,489...136,209
Ensembl chrNW_004955604:124,686...136,901 		JBrowse link
G Prpf8 pre-mRNA processing factor 8 involved_in ISO (PMID:20595234) UniProt PMID:20595234 NCBI chrNW_004955481:1,499,634...1,530,670
Ensembl chrNW_004955481:1,499,634...1,530,670 		JBrowse link
G Sart3 spliceosome associated factor 3, U4/U6 recycling protein involved_in ISO (PMID:12032085), (PMID:20595234) UniProt PMID:12032085 PMID:20595234 NCBI chrNW_004955455:9,802,260...9,833,326
Ensembl chrNW_004955455:9,802,260...9,832,957 		JBrowse link
G Tssc4 tumor suppressing subtransferable candidate 4 involved_in ISO (PMID:34131137) UniProt PMID:34131137 NCBI chrNW_004955422:14,175,271...14,178,991
Ensembl chrNW_004955422:14,175,271...14,178,991 		JBrowse link
G Usp4 ubiquitin specific peptidase 4 involved_in ISO (PMID:20595234) UniProt PMID:20595234 NCBI chrNW_004955532:1,247,110...1,284,564
Ensembl chrNW_004955532:1,247,110...1,285,121 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12362
    cellular process 11459
      cellular component organization or biogenesis 5382
        cellular component biogenesis 2646
          ribonucleoprotein complex biogenesis 277
            protein-RNA complex assembly 121
              spliceosomal snRNP assembly 28
                spliceosomal tri-snRNP complex assembly 9
Path 2
Term Annotations click to browse term
  biological_process 12362
    metabolic process 7488
      primary metabolic process 6455
        nucleobase-containing compound metabolic process 3737
          nucleic acid metabolic process 3370
            RNA metabolic process 2899
              RNA biosynthetic process 2744
                RNA processing 583
                  RNA splicing 276
                    RNA splicing, via transesterification reactions 219
                      RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 219
                        mRNA splicing, via spliceosome 219
                          spliceosomal snRNP assembly 28
                            spliceosomal tri-snRNP complex assembly 9
paths to the root