RGD DISEASE ONTOLOGY - ANNOTATIONS
RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term: Familial Thoracic Aortic Aneurysm 1
Accession: DOID:9008615
browse the term
Synonyms: exact_synonym: AAT1; Annuloaortic Ectasia; FAA1; Familial Aortic Aneurysm; Familial Aortic Dissection; Familial Taad; Familial Thoracic Aortic Aneurysm; familial thoracic aortic aneurysm and dissection; thoracic aortic aneurysm
narrow_synonym: Erdheim cystic medial necrosis of aorta
primary_id: MESH:C562834
alt_id: OMIM:607086
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Acta2
actin alpha 2, smooth muscle
ISO
ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:25741868 PMID:28492532
NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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Col3a1
collagen type III alpha 1 chain
ISO
ClinVar Annotator: match by term: Annuloaortic ectasia
ClinVar
PMID:7695699 PMID:8218237 PMID:19344236 PMID:24922459 PMID:25758994 PMID:28492532 More...
NCBI chr 9:47,374,611...47,410,547
Ensembl chr 9:47,374,593...47,410,547
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Fbn1
fibrillin 1
ISO
ClinVar Annotator: match by term: AORTIC ANEURYSM, FAMILIAL THORACIC 1 | ClinVar Annotator: match by term: Annuloaortic ectasia | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:7870075 PMID:8653794 PMID:8723076 PMID:9399842 PMID:9837823 PMID:10633129 PMID:11524736 PMID:11748851 PMID:11826022 PMID:11933199 PMID:11992479 PMID:12938084 PMID:14695540 PMID:16222657 PMID:17418587 PMID:17627385 PMID:17657824 PMID:18435798 PMID:19161152 PMID:19293843 PMID:19618372 PMID:19863550 PMID:20082464 PMID:21542060 PMID:21895641 PMID:23506379 PMID:23577066 PMID:24033266 PMID:24793577 PMID:24941995 PMID:25101912 PMID:25326635 PMID:25637381 PMID:25741868 PMID:25812041 PMID:25852444 PMID:25907466 PMID:26272055 PMID:26621581 PMID:26787436 PMID:26875674 PMID:27112580 PMID:27153395 PMID:27582083 PMID:27959697 PMID:28492532 PMID:28655553 PMID:28659821 PMID:29357934 PMID:29543232 PMID:30371227 PMID:31211626 PMID:31227806 PMID:31506931 PMID:32123317 PMID:35058154 PMID:35943490 More...
NCBI chr 3:112,554,257...112,750,835
Ensembl chr 3:112,554,925...112,750,889
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Foxe3
forkhead box E3
ISO
ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:26854927 PMID:28492532 PMID:29314435
NCBI chr 5:128,444,912...128,446,494
Ensembl chr 5:128,445,594...128,446,454
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Lox
lysyl oxidase
ISO
ClinVar Annotator: match by term: Familial aortic dissection | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:12417550 PMID:26838787 PMID:27432961 PMID:28492532 PMID:29961567 PMID:30675029 PMID:31211696 PMID:31459939 More...
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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Myh11
myosin heavy chain 11
ISO
ClinVar Annotator: match by term: Annuloaortic ectasia | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:22511748 PMID:24033266 PMID:25433566 PMID:25637381 PMID:25741868 PMID:26017485 PMID:26332594 PMID:27879251 PMID:28492532 PMID:29494672 PMID:29961567 PMID:33726816 More...
NCBI chr10:743,364...838,459
Ensembl chr10:743,685...838,459
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Mylk
myosin light chain kinase
ISO
ClinVar Annotator: match by term: Annuloaortic ectasia | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:25637381 PMID:25741868 PMID:27879251 PMID:28492532
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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Nde1
nudE neurodevelopment protein 1
ISO
ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:25741868 PMID:28492532
NCBI chr10:839,788...883,946
Ensembl chr10:839,788...883,869
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Smad3
SMAD family member 3
ISO
ClinVar Annotator: match by term: Annuloaortic ectasia | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:28492532
NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960
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Srfbp1
serum response factor binding protein 1
ISO
ClinVar Annotator: match by term: Familial aortic dissection | ClinVar Annotator: match by term: Familial thoracic aortic aneurysm
ClinVar
PMID:12417550 PMID:26838787 PMID:27432961 PMID:28492532 PMID:29961567 PMID:30675029 PMID:31211696 PMID:31459939 More...
NCBI chr18:45,920,389...45,945,385
Ensembl chr18:45,920,446...45,942,515
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Tgfbr2
transforming growth factor, beta receptor 2
ISO
ClinVar Annotator: match by term: Annuloaortic ectasia
ClinVar
PMID:8246946 PMID:11212236 PMID:16791849 PMID:16928994 PMID:17061023 PMID:17319955 PMID:17344846 PMID:17935258 PMID:18781618 PMID:21270064 PMID:21524434 PMID:24033266 PMID:24055113 PMID:24793577 PMID:24941995 PMID:25203624 PMID:25637381 PMID:25741868 PMID:26017485 PMID:26133393 PMID:27930701 PMID:28162229 PMID:28492532 PMID:30222965 PMID:34572573 More...
NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228
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