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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Subdural Hematoma
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Accession:DOID:9001521 term browser browse the term
Definition:Accumulation of blood in the SUBDURAL SPACE between the DURA MATER and the arachnoidal layer of the MENINGES. This condition primarily occurs over the surface of a CEREBRAL HEMISPHERE, but may develop in the spinal canal (HEMATOMA, SUBDURAL, SPINAL). Subdural hematoma can be classified as the acute or the chronic form, with immediate or delayed symptom onset, respectively. Symptoms may include loss of consciousness, severe HEADACHE, and deteriorating mental status.
Synonyms:exact_synonym: Subdural Hemorrhage;   Subdural Hemorrhages;   Traumatic Subdural Hematoma;   subdural hematomas;   traumatic subdural hematomas
 primary_id: MESH:D006408


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Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:1899364 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
Acute Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin treatment ISO RGD PMID:23415790 RGD:10401075 NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12503044 NCBI chr16:76,489,775...76,500,636
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 treatment IMP RGD PMID:15379997 RGD:329969897 NCBI chr 1:79,956,380...79,974,354
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
Intracranial Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein VI exacerbates ISO RGD PMID:21258336 RGD:401824683 NCBI chr 1:69,429,232...69,492,709
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IMP RGD PMID:34334113 RGD:155882538 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 treatment IMP
IEP		 protein:increased expression:brain (rat) RGD PMID:34334113 PMID:34334113 RGD:155882538, RGD:155882538 NCBI chr 3:29,214,581...29,344,890
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 18969
    Pathological Conditions, Signs and Symptoms 13343
      Pathologic Processes 7990
        Hemorrhage 305
          Intracranial Hemorrhages 163
            Subdural Hematoma 7
              Acute Subdural Hematoma 3
              Chronic Subdural Hematoma 0
              Intracranial Subdural Hematoma 3
              Spinal Subdural Hematoma 0
Path 2
Term Annotations click to browse term
  disease 18969
    disease of anatomical entity 18249
      nervous system disease 14090
        central nervous system disease 12430
          brain disease 11668
            cerebrovascular disease 1000
              Intracranial Hemorrhages 163
                Traumatic Intracranial Hemorrhage 8
                  Subdural Hematoma 7
                    Acute Subdural Hematoma 3
                    Chronic Subdural Hematoma 0
                    Intracranial Subdural Hematoma 3
                    Spinal Subdural Hematoma 0
paths to the root