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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:Intracranial Hemorrhages
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Accession:DOID:9003104 term browser browse the term
Definition:Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
Synonyms:exact_synonym: Brain Hemorrhage;   Brain Hemorrhages;   Posterior Fossa Hemorrhage;   intracranial hemorrhage;   posterior fossa hemorrhages
 primary_id: MESH:D020300
 xref: EFO:0000551


show annotations for term's descendants           Sort by:
Intracranial Hemorrhages term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Col4a1 collagen type IV alpha 1 chain ISO ClinVar Annotator: match by term: Intracranial Hemorrhages ClinVar PMID:7695699 PMID:8218237 PMID:9016532 PMID:16598045 PMID:17078022 More... NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:15595332 PMID:16159073 PMID:18617125 PMID:20172985 PMID:20522813 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Hbb hemoglobin subunit beta IEP mRNA:increased expression:basal ganglion, neuron, glial cell RGD PMID:21725744 RGD:10449050 NCBI chr 1:167,662,310...167,663,721
Ensembl chr 1:158,120,200...158,252,012 		JBrowse link
G Hspb1 heat shock protein family B (small) member 1 IEP protein:increased expression:brain: RGD PMID:15472083 RGD:10402769 NCBI chr12:26,430,640...26,432,301
Ensembl chr12:20,794,028...20,795,743 		JBrowse link
G Il6 interleukin 6 susceptibility ISO DNA:polymorphism:promoter -174G>C(human) RGD PMID:15331795 RGD:12792203 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nos3 nitric oxide synthase 3 treatment IMP RGD PMID:29203281 RGD:13504724 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nsd2 nuclear receptor binding SET domain protein 2 ISO ClinVar Annotator: match by term: Intracranial Hemorrhages ClinVar PMID:25741868 NCBI chr14:76,833,179...76,911,304
Ensembl chr14:76,835,637...76,913,641 		JBrowse link
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:2104561 PMID:3168586 PMID:7902905 PMID:8961984 PMID:11320361 More... NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase IMP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10392865 PMID:10472989 PMID:10512912 PMID:17308290 PMID:21779364 RGD:6484131 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Ppp1r1b protein phosphatase 1, regulatory (inhibitor) subunit 1B IEP RGD PMID:23543809 RGD:13515075 NCBI chr10:83,347,731...83,356,775
Ensembl chr10:83,347,731...83,356,775 		JBrowse link
G Psen1 presenilin 1 ISO RGD PMID:9160754 RGD:1302520 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Serping1 serpin family G member 1 treatment ISO associated with Stroke RGD PMID:21779364 RGD:6484131 NCBI chr 3:69,842,726...69,852,583
Ensembl chr 3:69,842,739...69,852,034 		JBrowse link
G Shoc2 SHOC2 leucine-rich repeat scaffold protein IEP mRNA:decreased expression:brain: RGD PMID:34368865 RGD:155804268 NCBI chr 1:252,958,939...253,048,820
Ensembl chr 1:252,959,723...253,047,337 		JBrowse link
G Slc23a1 solute carrier family 23 member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:11984597 NCBI chr18:27,490,549...27,504,563
Ensembl chr18:27,216,281...27,230,697 		JBrowse link
G Tf transferrin IEP associated with Iron-Deficiency Anemia;protein:increased expression:basal ganglia RGD PMID:16671451 RGD:1601537 NCBI chr 8:112,668,667...112,695,376
Ensembl chr 8:103,767,995...103,816,511 		JBrowse link
G Tnf tumor necrosis factor ISO RGD PMID:16322490 RGD:1580310 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Ubiad1 UbiA prenyltransferase domain containing 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:23533172 NCBI chr 5:158,856,582...158,880,490
Ensembl chr 5:158,868,672...158,880,271 		JBrowse link
Acute Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Epo erythropoietin treatment ISO RGD PMID:23415790 RGD:10401075 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:12503044 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Kcnn4 potassium calcium-activated channel subfamily N member 4 treatment IMP RGD PMID:15379997 RGD:329969897 NCBI chr 1:89,084,306...89,102,279
Ensembl chr 1:79,959,322...79,974,340 		JBrowse link
APP-related cerebral amyloid angiopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G App amyloid beta precursor protein ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: AMYLOIDOSIS, CEREBROARTERIAL, APP-RELATED | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ARCTIC VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, FLEMISH VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, IOWA VARIANT | ClinVar Annotator: match by term: CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED, ITALIAN VARIANT | ClinVar Annotator: match by term: Cerebral amyloid angiopathy, APP-related		 CTD
ClinVar
OMIM		 PMID:1303172 PMID:1303239 PMID:1303275 PMID:1415269 PMID:1520398 More... NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
Basal Ganglia Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gsn gelsolin severity ISO protein:decreased expression:blood plasma (human) RGD PMID:23142649 RGD:329333032 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
Cerebral Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ace angiotensin I converting enzyme ISO CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to | ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to		 CTD
ClinVar		 PMID:1313972 PMID:1319114 PMID:1328889 PMID:1386652 PMID:1976655 More... NCBI chr10:91,410,129...91,430,246
Ensembl chr10:90,910,316...90,931,131 		JBrowse link
G Anxa1 annexin A1 IEP mRNA:increased expression:brain RGD PMID:16034371 RGD:2306905 NCBI chr 1:227,287,713...227,306,739
Ensembl chr 1:217,861,175...217,877,343 		JBrowse link
G Apex1 apurinic/apyrimidinic endodeoxyribonuclease 1 IEP RGD PMID:15344903 RGD:2315676 NCBI chr15:26,618,146...26,620,330
Ensembl chr15:24,144,362...24,146,785 		JBrowse link
G Apoe apolipoprotein E ISO DNA:missense mutations, haplotype:cds:p.C112R (rs7412) (human) RGD PMID:19251191 RGD:6904207 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Aqp4 aquaporin 4 IEP RGD PMID:25545558 RGD:11541062 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Atp6v1a ATPase H+ transporting V1 subunit A IEP protein:decreased expression:brain RGD PMID:30307711 RGD:408426007 NCBI chr11:70,066,800...70,120,603
Ensembl chr11:56,560,974...56,614,694 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr 1:105,076,472...105,081,906
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l1 Bcl2-like 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12721362 NCBI chr 3:161,713,777...161,764,844
Ensembl chr 3:141,253,523...141,303,479
Ensembl chr 1:141,253,523...141,303,479 		JBrowse link
G Bdnf brain-derived neurotrophic factor ISO RGD PMID:20818776 RGD:4891129 NCBI chr 3:116,619,633...116,670,212
Ensembl chr 3:96,165,042...96,215,615 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:basal ganglion RGD PMID:23884876 RGD:11561935 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bnip3l BCL2 interacting protein 3 like IEP RGD PMID:23771482 RGD:7483577 NCBI chr15:45,350,081...45,373,213
Ensembl chr15:41,174,594...41,197,803 		JBrowse link
G C3 complement C3 IEP RGD PMID:17114852 RGD:5129540 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Car2 carbonic anhydrase 2 IEP protein:increased expression:brain RGD PMID:30307711 RGD:408426007 NCBI chr 2:88,462,883...88,478,012
Ensembl chr 2:86,741,626...86,756,818 		JBrowse link
G Casp12 caspase 12 treatment IEP RGD PMID:28544790 RGD:13782167 NCBI chr 8:10,927,188...10,954,442
Ensembl chr 8:2,642,434...2,674,037 		JBrowse link
G Casp3 caspase 3 treatment
ameliorates		 ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17971790 PMID:28096675 PMID:31376096 RGD:13782306, RGD:329337378 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 treatment ISO
IEP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:17971790 PMID:28096675 RGD:13782306 NCBI chr 9:67,747,109...67,806,699
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 treatment IEP RGD PMID:28096675 RGD:13782306 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Cd14 CD14 molecule IEP mRNA:increased expression:lung, intestine: RGD PMID:19534684 RGD:7185660 NCBI chr18:28,609,558...28,611,409
Ensembl chr18:28,335,340...28,337,261 		JBrowse link
G Cd36 CD36 molecule ISO RGD PMID:19064796 RGD:6893504 NCBI chr 4:18,209,088...18,302,142
Ensembl chr 4:17,354,466...17,513,903 		JBrowse link
G Cfh complement factor H severity ISO RGD PMID:21871809 RGD:5684553 NCBI chr13:54,063,079...54,164,523
Ensembl chr13:51,511,828...51,613,838 		JBrowse link
G Cntf ciliary neurotrophic factor ISO CTD Direct Evidence: therapeutic CTD PMID:11701153 NCBI chr 1:219,312,512...219,314,535
Ensembl chr 1:209,887,854...209,889,877 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to | ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD
RGD		 PMID:3691802 PMID:7695699 PMID:8218237 PMID:9016532 PMID:9536098 More... RGD:1581204 NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain susceptibility ISO DNA:SNPs::
ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: COL4A2-Related Disorder | ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to		 OMIM
ClinVar
CTD
RGD		 PMID:22209247 PMID:22333902 PMID:22914737 PMID:24390199 PMID:24646874 More... RGD:13450933 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Csf3 colony stimulating factor 3 treatment ISO RGD PMID:19169816 RGD:11039433 NCBI chr10:84,157,485...84,159,860
Ensembl chr10:83,661,207...83,663,603 		JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 treatment IMP RGD PMID:24955809 RGD:11352686 NCBI chr13:42,630,383...42,634,288
Ensembl chr13:40,077,976...40,081,883 		JBrowse link
G Dag1 dystroglycan 1 IEP RGD PMID:25545558 RGD:11541062 NCBI chr 8:117,769,517...117,834,347
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Dcx doublecortin IEP protein:increased expression:dentate gyrus RGD PMID:24144742 RGD:12904766 NCBI chr  X:112,227,455...112,370,291
Ensembl chr  X:107,430,767...107,507,476 		JBrowse link
G F13a1 coagulation factor XIII A1 chain ISO RGD PMID:9550516 RGD:1581027 NCBI chr17:28,021,197...28,197,960
Ensembl chr17:27,815,702...27,992,700 		JBrowse link
G F2 coagulation factor II, thrombin severity ISO protein:increased expression:plasma RGD PMID:21244583 RGD:5147770 NCBI chr 3:98,051,958...98,065,246
Ensembl chr 3:77,596,198...77,609,486 		JBrowse link
G F7 coagulation factor VII treatment ISO human protein in a rat model
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:16671457 PMID:21127298 PMID:16671457 RGD:11049545 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
G Flt1 Fms related receptor tyrosine kinase 1 IEP
ISO		 mRNA:increased expression:brain:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17888890 PMID:17888890 RGD:10402152 NCBI chr12:12,333,050...12,504,750
Ensembl chr12:7,297,292...7,468,626 		JBrowse link
G Fto FTO, alpha-ketoglutarate dependent dioxygenase ISO protein:increased expression:thalamic complex RGD PMID:34102854 RGD:329812008 NCBI chr19:31,456,749...31,865,011
Ensembl chr19:15,349,696...15,692,083 		JBrowse link
G Gdnf glial cell derived neurotrophic factor treatment IMP RGD PMID:21311297 RGD:405878068 NCBI chr 2:58,621,327...58,647,242
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gp6 glycoprotein VI ameliorates ISO associated with hypertension RGD PMID:33556561 RGD:401794565 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Hmox1 heme oxygenase 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:12401953 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hmox2 heme oxygenase 2 ISO CTD Direct Evidence: therapeutic CTD PMID:16459095 NCBI chr10:10,797,076...10,831,178
Ensembl chr10:10,797,055...10,831,148 		JBrowse link
G Hp haptoglobin treatment ISO RGD PMID:20016097 PMID:20016097 RGD:11041810, RGD:11041810 NCBI chr19:54,449,151...54,453,701
Ensembl chr19:37,539,627...37,544,523 		JBrowse link
G Ifnb1 interferon beta 1 exacerbates ISO RGD PMID:29301581 RGD:401854231 NCBI chr 5:108,066,650...108,067,487
Ensembl chr 5:103,020,969...103,021,523 		JBrowse link
G Il1b interleukin 1 beta ameliorates IEP RGD PMID:31376096 RGD:329337378 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist treatment IEP
ISO		 mRNA:increased expression:striatum (rat)
human gene in a rat model		 RGD PMID:22707991 PMID:14753487 RGD:6997504, RGD:8551833 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 ameliorates IEP RGD PMID:31376096 RGD:329337378 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Itga2b integrin subunit alpha 2b ISO CTD Direct Evidence: marker/mechanism CTD PMID:9445356 NCBI chr10:87,908,697...87,926,225
Ensembl chr10:87,408,536...87,426,168 		JBrowse link
G Itgav integrin subunit alpha V ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9445356 PMID:16102435 RGD:1582447 NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639 		JBrowse link
G Itgb2 integrin subunit beta 2 ISO RGD PMID:18615643 RGD:6482197 NCBI chr20:11,061,009...11,097,242
Ensembl chr20:11,061,430...11,097,600 		JBrowse link
G Itgb3 integrin subunit beta 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:9445356 NCBI chr10:90,009,927...90,067,787
Ensembl chr10:89,509,989...89,564,679 		JBrowse link
G Kat6b lysine acetyltransferase 6B ISO ClinVar Annotator: match by term: Stroke, hemorrhagic, susceptibility to ClinVar PMID:25741868 NCBI chr15:2,688,535...2,861,443
Ensembl chr15:2,639,200...2,812,316 		JBrowse link
G Kdr kinase insert domain receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:17888890 NCBI chr14:32,572,031...32,615,204
Ensembl chr14:32,217,871...32,261,018 		JBrowse link
G Lcn2 lipocalin 2 IEP RGD PMID:23416150 RGD:126790480 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Map1lc3a microtubule-associated protein 1 light chain 3 alpha IEP RGD PMID:23884876 RGD:11561935 NCBI chr 3:164,243,204...164,244,850
Ensembl chr 3:143,783,024...143,784,670 		JBrowse link
G Mir126a microRNA 126a ameliorates IMP RGD PMID:32160957 RGD:401851064 NCBI chr 3:29,813,150...29,813,267
Ensembl chr 3:9,415,063...9,415,180 		JBrowse link
G Mir140 microRNA 140 ameliorates IMP RGD PMID:31376096 RGD:329337378 NCBI chr19:52,375,293...52,375,391
Ensembl chr19:35,465,577...35,465,675 		JBrowse link
G Mir152 microRNA 152 treatment IDA RGD PMID:31982825 RGD:21066340 NCBI chr10:82,329,383...82,329,467
Ensembl chr10:81,832,936...81,833,020 		JBrowse link
G Mir23a microRNA 23a ameliorates IMP
ISO		 RNA:increased expression:serum RGD PMID:33403590 PMID:29771433 RGD:155882539, RGD:155882557 NCBI chr19:40,859,769...40,859,843
Ensembl chr19:23,954,997...23,955,071 		JBrowse link
G Mmp12 matrix metallopeptidase 12 IDA
ISO		 RGD PMID:12783419 PMID:15654856 RGD:1582362, RGD:1582358 NCBI chr 8:12,866,652...12,876,554
Ensembl chr 8:4,581,785...4,599,611 		JBrowse link
G Mmp2 matrix metallopeptidase 2 ISO CTD Direct Evidence: marker/mechanism CTD PMID:10698078 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp3 matrix metallopeptidase 3 ISO CTD Direct Evidence: marker/mechanism CTD PMID:17971790 NCBI chr 8:12,925,267...12,938,828
Ensembl chr 8:4,640,416...4,653,961 		JBrowse link
G Mmp9 matrix metallopeptidase 9 ISO CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:14630814 PMID:15488484 PMID:15529013 PMID:16190367 PMID:19095969 More... RGD:1582637 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Mt1 metallothionein 1 IEP mRNA:increased expression:cerebral cortex, striatum (rat) RGD PMID:16034371 RGD:2306905 NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049
Ensembl chr  X:10,826,032...10,827,049 		JBrowse link
G Mt2 metallothionein 2 IEP mRNA:increased expression:cerebral cortex, striatum (rat) RGD PMID:16034371 RGD:2306905 NCBI chr19:10,837,934...10,838,708
Ensembl chr19:10,832,002...10,832,784 		JBrowse link
G Mtor mechanistic target of rapamycin kinase treatment IMP RGD PMID:24602288 RGD:10041041 NCBI chr 5:164,167,985...164,277,438
Ensembl chr 5:158,884,804...158,994,311 		JBrowse link
G Nfkb1 nuclear factor kappa B subunit 1 IDA protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 2:226,689,745...226,805,897
Ensembl chr 2:224,016,214...224,110,404 		JBrowse link
G Nfkb2 nuclear factor kappa B subunit 2 IDA protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 1:255,106,010...255,114,649
Ensembl chr 1:245,165,950...245,173,213 		JBrowse link
G Nfkbia NFKB inhibitor alpha IDA protein:increased phosphorylation:brain RGD PMID:20150961 RGD:10413872 NCBI chr 6:78,593,844...78,597,307
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nppb natriuretic peptide B ISO CTD Direct Evidence: therapeutic CTD PMID:19803787 NCBI chr 5:163,699,955...163,701,314
Ensembl chr 5:158,416,866...158,418,168 		JBrowse link
G Npy neuropeptide Y IEP protein:increased expression:plasma (rat) RGD PMID:15068713 RGD:1580182 NCBI chr 4:80,212,111...80,219,310
Ensembl chr 4:78,881,264...78,888,495 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 treatment IEP RGD PMID:29050310 RGD:13442476 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Plat plasminogen activator, tissue type treatment
severity		 IDA
ISO		 human protein in a rat model
CTD Direct Evidence: marker/mechanism
associated with Brain Injuries		 CTD
RGD		 PMID:1430592 PMID:1579960 PMID:1899364 PMID:7477192 PMID:7723950 More... RGD:11537477, RGD:11541064 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
G Plau plasminogen activator, urokinase ISO CTD Direct Evidence: marker/mechanism CTD PMID:1265806 PMID:8025938 PMID:9731615 PMID:15181847 PMID:17702958 NCBI chr15:3,505,485...3,511,987
Ensembl chr15:3,456,232...3,462,775 		JBrowse link
G Plod3 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3 ISO ClinVar Annotator: match by term: Hemorrhage, intracerebral, susceptibility to ClinVar PMID:25741868 PMID:28492532 NCBI chr12:19,676,384...19,686,945
Ensembl chr12:19,676,386...19,686,960 		JBrowse link
G Pomc proopiomelanocortin ISO CTD Direct Evidence: marker/mechanism CTD PMID:6254450 NCBI chr 6:32,659,137...32,665,175
Ensembl chr 6:26,939,837...26,945,664 		JBrowse link
G Psen1 presenilin 1 ISO RGD PMID:16079160 RGD:1580694 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 IEP
ISO		 protein:increased expression:neuron, astrocyte, blood vessel RGD PMID:21385433 PMID:21385433 RGD:5508223, RGD:5508223 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rad21 RAD21 cohesin complex component severity IMP RGD PMID:36538854 RGD:243065265 NCBI chr 7:85,177,715...85,204,657
Ensembl chr 7:83,287,870...83,314,817 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit IDA protein:increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Relb RELB proto-oncogene, NF-kB subunit IDA mRNA, protein:increased expression, increased activity:striatum RGD PMID:17250675 RGD:2302394 NCBI chr 1:88,385,717...88,413,380
Ensembl chr 1:79,257,725...79,285,507 		JBrowse link
G S100b S100 calcium binding protein B disease_progression ISO CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19027832 PMID:19505208 RGD:5508801 NCBI chr20:12,372,345...12,381,159
Ensembl chr20:12,372,881...12,394,743 		JBrowse link
G Serpina3n serpin family A member 3N ISO RGD PMID:12126519 RGD:1580109 NCBI chr 6:123,323,623...123,331,181
Ensembl chr 6:123,323,629...123,332,433 		JBrowse link
G Serpinc1 serpin family C member 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:6636041 NCBI chr13:75,790,558...75,804,826
Ensembl chr13:73,257,179...73,284,293 		JBrowse link
G Slc24a1 solute carrier family 24 member 1 IEP mRNA, protein:decreased expression:cerebrum RGD PMID:23564126 RGD:9685494 NCBI chr 8:65,440,842...65,466,001
Ensembl chr 8:65,440,730...65,466,001 		JBrowse link
G Slc8b1 solute carrier family 8 member B1 IEP RGD PMID:23564126 RGD:9685494 NCBI chr12:36,029,759...36,053,087
Ensembl chr12:36,029,760...36,053,031 		JBrowse link
G Spp1 secreted phosphoprotein 1 ISO CTD Direct Evidence: therapeutic CTD PMID:20440599 NCBI chr14:5,613,569...5,620,695
Ensembl chr14:5,308,885...5,315,162 		JBrowse link
G Sqstm1 sequestosome 1 IEP protein:decreased expression:basal ganglion RGD PMID:23884876 RGD:11561935 NCBI chr10:35,026,598...35,037,750
Ensembl chr10:34,525,519...34,536,673 		JBrowse link
G Thbs1 thrombospondin 1 IEP RGD PMID:20136391 RGD:2317938 NCBI chr 3:125,510,250...125,525,402
Ensembl chr 3:105,056,292...105,071,440 		JBrowse link
G Thbs2 thrombospondin 2 IEP RGD PMID:20136391 RGD:2317938 NCBI chr 1:64,343,523...64,372,918
Ensembl chr 1:55,670,394...55,699,789 		JBrowse link
G Tnf tumor necrosis factor ameliorates IEP RGD PMID:31376096 RGD:329337378 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Vegfa vascular endothelial growth factor A ISO CTD Direct Evidence: marker/mechanism CTD PMID:17888890 NCBI chr 9:22,452,854...22,468,194
Ensembl chr 9:14,955,300...14,970,641 		JBrowse link
Intracranial Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gp6 glycoprotein VI exacerbates ISO RGD PMID:21258336 RGD:401824683 NCBI chr 1:78,471,900...78,535,374
Ensembl chr 1:69,465,789...69,491,326 		JBrowse link
G Mdm2 MDM2 proto-oncogene treatment IMP RGD PMID:34334113 RGD:155882538 NCBI chr 7:55,176,558...55,201,757
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Zeb2 zinc finger E-box binding homeobox 2 treatment IMP
IEP		 protein:increased expression:brain (rat) RGD PMID:34334113 PMID:34334113 RGD:155882538, RGD:155882538 NCBI chr 3:49,624,028...49,754,323
Ensembl chr 3:29,218,301...29,345,157 		JBrowse link
Intraventricular Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bace1 beta-secretase 1 IEP protein:increased expression:hippocampus RGD PMID:30028260 RGD:13782136 NCBI chr 8:55,038,842...55,061,138
Ensembl chr 8:46,142,116...46,165,876 		JBrowse link
G Col4a1 collagen type IV alpha 1 chain ISO ClinVar Annotator: match by term: Intraventricular hemorrhage ClinVar PMID:7695699 PMID:8218237 PMID:9016532 PMID:16598045 PMID:17078022 More... NCBI chr16:84,885,597...84,996,482
Ensembl chr16:78,183,533...78,294,412 		JBrowse link
G Col4a2 collagen type IV alpha 2 chain ISO ClinVar Annotator: match by term: Intraventricular hemorrhage ClinVar PMID:25741868 PMID:33527515 NCBI chr16:84,749,672...84,885,520
Ensembl chr16:78,047,602...78,183,839 		JBrowse link
G Il6 interleukin 6 ISO associated with Premature Birth;protein:increased expression:serum: RGD PMID:22906886 RGD:12792208 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
pituitary apoplexy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Crh corticotropin releasing hormone ISO CTD Direct Evidence: marker/mechanism CTD PMID:12699433 PMID:12699434 NCBI chr 2:104,059,184...104,061,048
Ensembl chr 2:102,143,055...102,144,919 		JBrowse link
Preterm Intraventricular Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnot1 CCR4-NOT transcription complex, subunit 1 ISO ClinVar Annotator: match by term: Preterm intraventricular hemorrhage ClinVar PMID:25741868 NCBI chr19:9,255,190...9,346,574
Ensembl chr19:9,255,194...9,346,574 		JBrowse link
G Gsn gelsolin ISO protein:decreased expression:blood plasma (human) RGD PMID:28755273 RGD:329337382 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Sema6b semaphorin 6B ISO ClinVar Annotator: match by term: Grade I preterm intraventricular hemorrhage ClinVar PMID:31474318 NCBI chr 9:950,939...967,905
Ensembl chr 9:950,939...961,521 		JBrowse link
Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:24114458 RGD:10003028 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing ISO protein:increased expression:cerebrospinal fluid RGD PMID:22230897 RGD:8695949 NCBI chr11:91,226,524...91,240,244
Ensembl chr11:77,721,912...77,735,564 		JBrowse link
G Adora1 adenosine A1 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:18950269 NCBI chr13:48,210,922...48,247,826
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
G Ager advanced glycosylation end product-specific receptor IEP mRNA, protein:increased expression:brain RGD PMID:24291745 RGD:8696000 NCBI chr20:4,152,758...4,155,956
Ensembl chr20:4,147,890...4,151,078 		JBrowse link
G Aif1 allograft inflammatory factor 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr20:3,651,435...3,657,341
Ensembl chr20:3,646,777...3,652,668 		JBrowse link
G Apoe apolipoprotein E ISO GAD PMID:15118671 RGD:1331525 NCBI chr 1:88,481,889...88,485,816
Ensembl chr 1:79,353,916...79,357,932 		JBrowse link
G Aqp4 aquaporin 4 exacerbates IEP
IMP		 mRNA:increased expression:brain: RGD PMID:33574749 PMID:33574749 RGD:127284879, RGD:127284879 NCBI chr18:6,782,389...6,799,034
Ensembl chr18:6,507,903...6,524,856 		JBrowse link
G Aqp4em1Hrt aquaporin 4; TALEN induced mutant 1, Hrt exacerbates IMP RGD PMID:33574749 RGD:127284879
G Bcl2 BCL2, apoptosis regulator treatment IEP RGD PMID:26163325 RGD:13782347 NCBI chr13:23,204,464...23,366,900
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Becn1 beclin 1 IEP protein:increased expression:brain RGD PMID:22521819 RGD:6483046 NCBI chr10:86,731,649...86,747,002
Ensembl chr10:86,231,388...86,246,742 		JBrowse link
G Bnip3 BCL2 interacting protein 3 treatment IEP RGD PMID:23850688 RGD:11561986 NCBI chr 1:203,137,778...203,154,962
Ensembl chr 1:193,708,167...193,725,359 		JBrowse link
G C3 complement C3 treatment IEP RGD PMID:26518242 RGD:11040780 NCBI chr 9:2,174,412...2,201,339
Ensembl chr 9:2,087,437...2,114,429 		JBrowse link
G Casp3 caspase 3 treatment ISO
IDA		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24602480 PMID:26163325 RGD:13782347 NCBI chr16:52,395,539...52,413,794
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp9 caspase 9 treatment IDA RGD PMID:26163325 RGD:13782347 Ensembl chr 5:154,109,046...154,126,626 JBrowse link
G Ccl20 C-C motif chemokine ligand 20 IEP mRNA:increased expression:cerebral artery RGD PMID:17977275 RGD:7488893 NCBI chr 9:91,837,139...91,839,736
Ensembl chr 9:84,388,904...84,391,629 		JBrowse link
G Cxcl1 C-X-C motif chemokine ligand 1 IEP mRNA:increased expression:lung RGD PMID:20731855 RGD:4145368 NCBI chr14:17,477,542...17,479,321
Ensembl chr14:17,193,365...17,195,215 		JBrowse link
G Cybb cytochrome b-245 beta chain IEP Protein:increased expression:cerebral cortex
mRNA:increased expression:cerebral vessel:		 RGD PMID:16671452 PMID:12142572 RGD:1599680, RGD:11040582 NCBI chr  X:16,030,596...16,065,065
Ensembl chr  X:13,359,430...13,392,586 		JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 ISO DNA:snp:cds:p.I118V (human) RGD PMID:18566305 RGD:5685415 NCBI chr12:14,321,771...14,343,886
Ensembl chr12:9,015,383...9,285,008 		JBrowse link
G Ddit3 DNA-damage inducible transcript 3 treatment IEP RGD PMID:30226536 RGD:35316073 NCBI chr 7:65,001,695...65,006,517
Ensembl chr 7:63,116,380...63,121,201 		JBrowse link
G Edn1 endothelin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:8587695 NCBI chr17:22,660,799...22,666,687
Ensembl chr17:22,454,420...22,460,885 		JBrowse link
G Ednrb endothelin receptor type B ISO CTD Direct Evidence: marker/mechanism CTD PMID:8587695 NCBI chr15:87,055,490...87,086,765
Ensembl chr15:80,643,043...80,672,115 		JBrowse link
G Epo erythropoietin treatment ISO RGD PMID:23907045 RGD:10400909 NCBI chr12:24,841,285...24,844,725
Ensembl chr12:19,204,508...19,207,946 		JBrowse link
G Erbb4 erb-b2 receptor tyrosine kinase 4 treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 9:76,973,386...78,045,633
Ensembl chr 9:69,531,481...70,596,595 		JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 treatment IMP
IEP		 RGD PMID:29169414 PMID:30226536 RGD:34901873, RGD:35316073 NCBI chr10:91,826,663...91,920,976
Ensembl chr10:91,330,654...91,421,029 		JBrowse link
G Esr1 estrogen receptor 1 IEP protein:increased expression:dentate gyrus RGD PMID:23465388 RGD:8553242 NCBI chr 1:43,511,685...43,904,454
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gli1 GLI family zinc finger 1 IEP mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr 7:65,042,237...65,054,888
Ensembl chr 7:63,156,926...63,169,251 		JBrowse link
G Gpx3 glutathione peroxidase 3 ISO protein:increased expression:plasma RGD PMID:32326289 RGD:401827845 NCBI chr10:39,529,335...39,537,406
Ensembl chr10:39,028,570...39,037,035 		JBrowse link
G Gsk3b glycogen synthase kinase 3 beta treatment IDA RGD PMID:27026509 RGD:13792767 NCBI chr11:76,004,502...76,154,665
Ensembl chr11:62,504,316...62,648,646 		JBrowse link
G Gsn gelsolin disease_progression
severity		 IEP
ISO		 mRNA, protein:altered expression:cerebral cortex (rat)
protein:decreased expression:blood plasma (human)		 RGD PMID:25744577 PMID:23880145 RGD:11055426, RGD:329333027 NCBI chr 3:38,982,605...39,035,849
Ensembl chr 3:18,585,172...18,638,402 		JBrowse link
G Hcn1 hyperpolarization-activated cyclic nucleotide-gated potassium channel 1 IEP mRNA,protein:decreased expression:hippocampus: RGD PMID:22378889 RGD:9686397 NCBI chr 2:51,228,710...51,632,806
Ensembl chr 2:49,495,771...49,899,774 		JBrowse link
G Hif1a hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:brain RGD PMID:15703702 RGD:1626323 NCBI chr 6:98,357,788...98,405,068
Ensembl chr 6:92,624,390...92,669,261 		JBrowse link
G Hmox1 heme oxygenase 1 IMP
ISO
IEP		 mRNA:increased expression:subarachnoid space RGD PMID:16543643 PMID:14657544 PMID:19686725 RGD:1582702, RGD:1598406, RGD:4145300 NCBI chr19:13,452,365...13,479,823
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Hspd1 heat shock protein family D (Hsp60) member 1 IEP mRNA:increased expression:brain stem RGD PMID:14753490 RGD:1624246 NCBI chr 9:64,073,610...64,084,332
Ensembl chr 9:56,579,201...56,589,662 		JBrowse link
G Htr1b 5-hydroxytryptamine receptor 1B IEP RGD PMID:17542534 RGD:1626451 NCBI chr 8:82,513,572...82,534,670
Ensembl chr 8:82,517,360...82,534,549 		JBrowse link
G Icam1 intercellular adhesion molecule 1 IEP mRNA:increased expression:lung (rat) RGD PMID:20731855 RGD:4145368 NCBI chr 8:27,829,688...27,841,618
Ensembl chr 8:19,553,645...19,565,438 		JBrowse link
G Il1b interleukin 1 beta ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr 3:137,030,200...137,036,581
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist ISO rat model treated with human protein RGD PMID:22679224 RGD:7051590 NCBI chr 3:27,509,836...27,525,738
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Il6 interleukin 6 ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf9 interferon regulatory factor 9 ameliorates IMP RGD PMID:29480757 RGD:125093745 NCBI chr15:33,065,422...33,071,881
Ensembl chr15:29,095,789...29,101,236 		JBrowse link
G Kcnj10 potassium inwardly-rectifying channel, subfamily J, member 10 treatment IEP RGD PMID:22420318 RGD:8662908 NCBI chr13:87,334,510...87,367,747
Ensembl chr13:84,802,009...84,835,461 		JBrowse link
G Lcn2 lipocalin 2 ameliorates ISO RGD PMID:26463936 RGD:126781835 NCBI chr 3:36,078,432...36,081,851
Ensembl chr 3:15,680,687...15,684,095 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 treatment IEP RGD PMID:30226536 RGD:35316073 NCBI chr 1:16,505,387...16,723,899
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Map3k7 mitogen activated protein kinase kinase kinase 7 treatment IEP RGD PMID:29273596 RGD:155804269 NCBI chr 5:51,149,524...51,212,012
Ensembl chr 5:46,357,931...46,415,597 		JBrowse link
G Mmp1 matrix metallopeptidase 1 no_association ISO RGD PMID:11546917 RGD:1582365 NCBI chr 8:12,943,453...12,963,966
Ensembl chr 8:4,658,588...4,679,097 		JBrowse link
G Mmp13 matrix metallopeptidase 13 IDA RGD PMID:16961140 RGD:1582545 NCBI chr 8:12,782,829...12,793,108
Ensembl chr 8:4,497,960...4,508,239 		JBrowse link
G Mmp2 matrix metallopeptidase 2 IDA RGD PMID:22475348 RGD:8657107 NCBI chr19:30,327,643...30,355,856
Ensembl chr19:14,154,657...14,182,870 		JBrowse link
G Mmp9 matrix metallopeptidase 9 IEP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27157545 PMID:17410600 RGD:1642039 NCBI chr 3:174,103,474...174,111,434
Ensembl chr 3:153,683,858...153,692,120 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 treatment IEP RGD PMID:22304528 RGD:10412722 NCBI chr 3:81,001,529...81,031,165
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Ngb neuroglobin IEP protein:increased expression:cerebral cortex RGD PMID:24281943 RGD:9743950 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830 		JBrowse link
G Nlk nemo like kinase disease_progression IEP RGD PMID:23325309 RGD:12791279 NCBI chr10:63,467,388...63,590,960
Ensembl chr10:63,438,222...63,589,730 		JBrowse link
G Nos2 nitric oxide synthase 2 ISO mRNA:increased expression:brainstem, basilar artery (mouse)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17053178 PMID:21915076 RGD:5509046 NCBI chr10:64,313,335...64,349,221
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Nos3 nitric oxide synthase 3 IEP mRNA:increased expression:parietal cortex, arteriole (rat) RGD PMID:11273938 RGD:7794687 NCBI chr 4:11,686,088...11,706,604
Ensembl chr 4:10,793,834...10,814,166 		JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 IEP mRNA, protein:increased expression:brain RGD PMID:21259333 RGD:5133235 NCBI chr19:52,205,374...52,220,267
Ensembl chr19:35,295,573...35,310,557 		JBrowse link
G Nrg1 neuregulin 1 treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr16:65,954,084...67,007,484
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Ntn1 netrin 1 ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr10:52,899,933...53,098,591
Ensembl chr10:52,899,934...53,085,326 		JBrowse link
G Ntrk2 neurotrophic receptor tyrosine kinase 2 IDA RGD PMID:21193742 RGD:5684779 NCBI chr17:5,560,558...5,875,899
Ensembl chr17:5,559,043...5,869,136 		JBrowse link
G Pdcd10 programmed cell death 10 IEP protein:decreased expression:brain, microglial cell (rat) RGD PMID:32302649 RGD:401827168 NCBI chr 2:162,602,516...162,644,690
Ensembl chr 2:160,303,449...160,346,018 		JBrowse link
G Pdgfrb platelet derived growth factor receptor beta ameliorates IMP RGD PMID:29480757 RGD:125093745 NCBI chr18:56,770,348...56,809,228
Ensembl chr18:54,499,964...54,538,843 		JBrowse link
G Pik3cb phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 8:108,474,017...108,579,140
Ensembl chr 8:99,594,644...99,699,663 		JBrowse link
G Pkd1l1 polycystin 1 like 1, transient receptor potential channel interacting susceptibility ISO DNA:polymorphism:cds:p.Gly243Asp(human) RGD PMID:16741147 RGD:155630602 NCBI chr14:83,552,964...83,670,062
Ensembl chr14:83,545,469...83,638,498 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr 4:150,095,743...150,221,104
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase treatment IEP RGD PMID:28546552 RGD:13432565 NCBI chr 1:51,236,410...52,430,242
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Ptch1 patched 1 IEP mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr17:1,548,449...1,613,461
Ensembl chr17:1,542,877...1,607,333 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 ISO RGD PMID:21725746 RGD:5508204 NCBI chr13:64,714,063...64,722,320
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit ISO CTD Direct Evidence: marker/mechanism CTD PMID:27157545 NCBI chr 1:212,354,336...212,364,815
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Shh sonic hedgehog signaling molecule IEP mRNA, protein:increased expression:brain RGD PMID:23933201 RGD:12859044 NCBI chr 4:7,687,872...7,697,025
Ensembl chr 4:6,954,017...6,963,170 		JBrowse link
G Smo smoothened, frizzled class receptor treatment IDA RGD PMID:28149272 RGD:150521623 NCBI chr 4:59,311,084...59,341,280
Ensembl chr 4:58,343,529...58,373,829 		JBrowse link
G Stat3 signal transducer and activator of transcription 3 IEP mRNA, protein:increased expression, increased phosphorylation:cerebral artery RGD PMID:24517975 RGD:8694356 NCBI chr10:86,311,528...86,363,513
Ensembl chr10:85,811,218...85,863,057 		JBrowse link
G Tacr1 tachykinin receptor 1 IMP RGD PMID:17542534 RGD:1626451 NCBI chr 4:116,478,617...116,647,492
Ensembl chr 4:114,920,844...115,089,733 		JBrowse link
G Tjp1 tight junction protein 1 IDA protein:altered localization RGD PMID:18854840 RGD:2325137 NCBI chr 1:128,260,330...128,505,018
Ensembl chr 1:118,849,838...119,094,432 		JBrowse link
G Tlr4 toll-like receptor 4 IEP mRNA, protein:increased expression:brain RGD PMID:19719951 RGD:4144093 NCBI chr 5:85,161,247...85,174,882
Ensembl chr 5:80,145,826...80,159,628 		JBrowse link
G Tmbim6 transmembrane BAX inhibitor motif containing 6 treatment IDA
IEP		 mRNA,protein:decreased expression:brain RGD PMID:30226536 PMID:30226536 RGD:35316073, RGD:35316073 NCBI chr 7:132,405,217...132,422,492
Ensembl chr 7:130,527,316...130,543,633 		JBrowse link
G Tnc tenascin C IEP protein:increased expression:basilar artery RGD PMID:19589197 RGD:4889600 NCBI chr 5:82,391,340...82,476,197
Ensembl chr 5:77,375,851...77,460,624 		JBrowse link
G Tnf tumor necrosis factor IEP
ISO		 protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:27157545 PMID:19719951 RGD:4144093 NCBI chr20:3,626,685...3,629,303
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Trem1 triggering receptor expressed on myeloid cells 1 treatment
severity		 IEP
ISO		 RGD PMID:30910643 PMID:33727099 RGD:127284863, RGD:127284864 NCBI chr 9:20,259,227...20,276,879
Ensembl chr 9:12,763,819...12,779,203 		JBrowse link
G Trpm4 transient receptor potential cation channel, subfamily M, member 4 IEP protein:increased expression:entorhinal cortex RGD PMID:24114458 RGD:10003028 NCBI chr 1:95,781,805...95,812,095
Ensembl chr 1:95,782,000...95,812,532 		JBrowse link
G Unc5b unc-5 netrin receptor B ISO CTD Direct Evidence: marker/mechanism CTD PMID:29162556 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Yap1 Yes1 associated transcriptional regulator treatment ISO RGD PMID:28756200 RGD:151893490 NCBI chr 8:13,380,551...13,451,640
Ensembl chr 8:5,095,722...5,167,010 		JBrowse link
Subdural Hematoma term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Plat plasminogen activator, tissue type ISO CTD Direct Evidence: marker/mechanism CTD PMID:1899364 NCBI chr16:75,943,061...76,022,037
Ensembl chr16:69,240,585...69,268,223 		JBrowse link
Traumatic Intracranial Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G F7 coagulation factor VII ISO CTD Direct Evidence: therapeutic CTD PMID:20370756 NCBI chr16:83,191,896...83,202,775
Ensembl chr16:76,489,717...76,500,610 		JBrowse link
Traumatic Subarachnoid Hemorrhage term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcc8 ATP binding cassette subfamily C member 8 treatment IMP RGD PMID:18854840 RGD:2325137 NCBI chr 1:105,734,992...105,816,272
Ensembl chr 1:96,598,647...96,679,510 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 19134
    Pathological Conditions, Signs and Symptoms 13617
      Pathologic Processes 8330
        Hemorrhage 310
          Intracranial Hemorrhages 165
            Cerebral Hemorrhage + 92
            Cranial Epidural Hematoma 0
            Hypertensive Intracranial Hemorrhage 0
            Subarachnoid Hemorrhage + 79
            Subdural Hematoma + 7
            Traumatic Intracranial Hemorrhage + 8
            pituitary apoplexy 1
Path 2
Term Annotations click to browse term
  disease 19134
    disease of anatomical entity 18447
      nervous system disease 14354
        central nervous system disease 12627
          brain disease 11847
            cerebrovascular disease 1005
              Intracranial Hemorrhages 165
                Cerebral Hemorrhage + 92
                Cranial Epidural Hematoma 0
                Hypertensive Intracranial Hemorrhage 0
                Subarachnoid Hemorrhage + 79
                Subdural Hematoma + 7
                Traumatic Intracranial Hemorrhage + 8
                pituitary apoplexy 1
paths to the root