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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:chlornitrofen
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Accession:CHEBI:3620 term browser browse the term
Definition:An aromatic ether that has formula C12H6Cl3NO3.
Synonyms:related_synonym: 2,4,6-Trichlorophenyl 4-nitrophenyl ether;   Formula=C12H6Cl3NO3;   InChI=1S/C12H6Cl3NO3/c13-7-5-10(14)12(11(15)6-7)19-9-3-1-8(2-4-9)16(17)18/h1-6H;   InChIKey=XQNAUQUKWRBODG-UHFFFAOYSA-N;   MC-338;   SMILES=C=1(C(=CC(Cl)=CC1Cl)Cl)OC=2C=CC(=CC2)[N+]([O-])=O;   chlornitrofene
 xref: CAS:1836-77-7;   KEGG:C11063
 xref_mesh: MESH:C010422
 xref: PPDB:2564;   Pesticides:chlornitrofen


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chlornitrofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
affects binding
ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of AR protein; 2,4,6-trichlorophenyl 4-nitrophenyl ether inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of AR protein]
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to AR protein
CTD PMID:12676605 PMID:15064155 NCBI chr  X:67,656,253...67,828,998
Ensembl chr  X:67,656,253...67,829,026
JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 mRNA; 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 protein CTD PMID:15110079 NCBI chr10:69,412,065...69,413,863
Ensembl chr10:69,412,017...69,413,870
JBrowse link
G Egr1 early growth response 1 increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of EGR1 mRNA CTD PMID:15110079 NCBI chr18:27,657,903...27,660,101
Ensembl chr18:27,657,628...27,661,429
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding
ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to ESR1 protein
CTD PMID:12676605 PMID:15064155 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of GADD45A mRNA CTD PMID:15110079 NCBI chr 4:97,782,512...97,784,814
Ensembl chr 4:97,782,512...97,784,842
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:65,022,100...65,058,546
Ensembl chr11:65,022,100...65,058,545
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:89,585,072...89,591,278
Ensembl chr13:89,586,283...89,591,277
JBrowse link
G Tnf tumor necrosis factor increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of TNF protein CTD PMID:15110079 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19771
    role 19716
      application 19406
        pesticide 16587
          herbicide 11822
            chlornitrofen 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19771
    subatomic particle 19770
      composite particle 19770
        hadron 19770
          baryon 19770
            nucleon 19770
              atomic nucleus 19770
                atom 19770
                  main group element atom 19658
                    p-block element atom 19658
                      carbon group element atom 19574
                        carbon atom 19564
                          organic molecular entity 19564
                            organic molecule 19497
                              organic cyclic compound 19321
                                carbocyclic compound 18297
                                  benzenoid aromatic compound 17402
                                    benzenes 17174
                                      chlorobenzenes 13593
                                        chlornitrofen 8
paths to the root