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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:chlornitrofen
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Accession:CHEBI:3620 term browser browse the term
Definition:An aromatic ether that has formula C12H6Cl3NO3.
Synonyms:related_synonym: 2,4,6-Trichlorophenyl 4-nitrophenyl ether;   Formula=C12H6Cl3NO3;   InChI=1S/C12H6Cl3NO3/c13-7-5-10(14)12(11(15)6-7)19-9-3-1-8(2-4-9)16(17)18/h1-6H;   InChIKey=XQNAUQUKWRBODG-UHFFFAOYSA-N;   MC-338;   SMILES=C=1(C(=CC(Cl)=CC1Cl)Cl)OC=2C=CC(=CC2)[N+]([O-])=O;   chlornitrofene
 xref: CAS:1836-77-7;   KEGG:C11063
 xref_mesh: MESH:C010422
 xref: PPDB:2564;   Pesticides:chlornitrofen


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chlornitrofen term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor multiple interactions
affects binding		 ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of AR protein; 2,4,6-trichlorophenyl 4-nitrophenyl ether inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; Dihydrotestosterone inhibits the reaction [2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of AR protein]
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to AR protein		 CTD PMID:12676605 PMID:15064155 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 mRNA; 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of CCL2 protein CTD PMID:15110079 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Egr1 early growth response 1 increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of EGR1 mRNA CTD PMID:15110079 NCBI chr18:26,463,333...26,465,531
Ensembl chr18:26,462,981...26,466,766 		JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
affects binding
increases activity		 ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether binds to ESR1 protein
2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of ESR1 protein		 CTD PMID:12676605 PMID:15064155 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Gadd45a growth arrest and DNA-damage-inducible, alpha increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of GADD45A mRNA CTD PMID:15110079 NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether binds to and results in increased activity of NR1I2 protein CTD PMID:21115097 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 increases activity ISO 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased activity of NR1I3 protein CTD PMID:28927721 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Tnf tumor necrosis factor increases expression EXP 2,4,6-trichlorophenyl 4-nitrophenyl ether results in increased expression of TNF protein CTD PMID:15110079 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19812
    role 19784
      application 19615
        pesticide 17441
          herbicide 13507
            chlornitrofen 8
Path 2
Term Annotations click to browse term
  CHEBI ontology 19812
    subatomic particle 19810
      composite particle 19810
        hadron 19810
          baryon 19810
            nucleon 19810
              atomic nucleus 19810
                atom 19810
                  main group element atom 19755
                    p-block element atom 19755
                      carbon group element atom 19698
                        carbon atom 19693
                          organic molecular entity 19693
                            organic molecule 19651
                              organic cyclic compound 19457
                                carbocyclic compound 18552
                                  benzenoid aromatic compound 17876
                                    benzenes 17716
                                      chlorobenzenes 14416
                                        chlornitrofen 8
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