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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:propoxur
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Accession:CHEBI:34938 term browser browse the term
Definition:A carbamate ester that is phenyl methylcarbamate substituted at position 2 by a propan-2-yloxy group.
Synonyms:exact_synonym: 2-(propan-2-yloxy)phenyl methylcarbamate
 related_synonym: 2-(1-methylethoxy)phenyl methylcarbamate;   2-Isopropoxyphenyl N-methylcarbamate;   2-Isopropoxyphenyl methylcarbamate;   Aprocarb;   Baygon;   Formula=C11H15NO3;   InChI=1S/C11H15NO3/c1-8(2)14-9-6-4-5-7-10(9)15-11(13)12-3/h4-8H,1-3H3,(H,12,13);   InChIKey=ISRUGXGCCGIOQO-UHFFFAOYSA-N;   SMILES=CNC(=O)Oc1ccccc1OC(C)C
 xref: CAS:114-26-1;   KEGG:C14334;   KEGG:D08442
 xref_mesh: MESH:D001074
 xref: PMID:19019354;   PMID:23201499;   PMID:24733834;   PMID:25016118;   PPDB:553;   Pesticides:propoxur;   Reaxys:1879891;   VSDB:553;   Wikipedia:Propoxur


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propoxur term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions
decreases activity
ISO
EXP
Obidoxime Chloride promotes the reaction [Propoxur results in decreased activity of ACHE protein]; pralidoxime promotes the reaction [Propoxur results in decreased activity of ACHE protein] CTD PMID:14644616, PMID:19934164, PMID:21251949, PMID:23962483 NCBI chr12:22,472,358...22,477,052
Ensembl chr12:22,472,358...22,478,753
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP [Carbaryl co-treated with Propoxur co-treated with Methiocarb co-treated with Methomyl co-treated with formetanate co-treated with oxamyl co-treated with Carbofuran] affects the activity of BCHE protein CTD PMID:22649187 NCBI chr 2:171,104,476...171,196,186
Ensembl chr 2:171,100,140...171,196,395
JBrowse link
G Cat catalase multiple interactions
decreases activity
EXP [Propoxur co-treated with Permethrin] results in increased activity of CAT protein; Melatonin inhibits the reaction [Propoxur results in decreased activity of CAT protein] CTD PMID:24733834, PMID:28456543 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Chrna4 cholinergic receptor nicotinic alpha 4 subunit multiple interactions EXP Propoxur results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 3:176,533,182...176,547,965
Ensembl chr 3:176,527,516...176,548,208
JBrowse link
G Chrnb4 cholinergic receptor nicotinic beta 4 subunit multiple interactions EXP Propoxur results in decreased activity of [CHRNA4 protein binds to CHRNB4 protein] CTD PMID:14644616 NCBI chr 8:59,610,489...59,629,073
Ensembl chr 8:59,609,693...59,629,133
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO Propoxur inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:9126867 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Pgr progesterone receptor multiple interactions ISO Propoxur inhibits the reaction [Progesterone results in increased activity of PGR protein] CTD PMID:9126867 NCBI chr 8:7,128,656...7,187,796
Ensembl chr 8:7,128,656...7,187,796
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19785
    role 19732
      application 19391
        agrochemical 14435
          propoxur 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19785
    subatomic particle 19782
      composite particle 19782
        hadron 19782
          baryon 19782
            nucleon 19782
              atomic nucleus 19782
                atom 19782
                  main group element atom 19670
                    p-block element atom 19670
                      carbon group element atom 19572
                        carbon atom 19561
                          organic molecular entity 19561
                            organic group 18493
                              organic divalent group 18486
                                organodiyl group 18486
                                  carbonyl group 18389
                                    carbonyl compound 18389
                                      carboxylic acid 18060
                                        amino acid 14072
                                          methylcarbamic acid 74
                                            propoxur 7
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