Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:5-aminoimidazole-4-carboxamide
go back to main search page
Accession:CHEBI:2030 term browser browse the term
Definition:An aminoimidazole in which the amino group is at C-5 with a carboxamido group at C-4.
Synonyms:related_synonym: 4-amino-1H-imidazole-5-carboxamide;   4-amino-5-carbamoylimidazole;   4-amino-5-imidazolecarboxamide;   5(4)-amino-4(5)-imidazolecarboxamide;   5-amino-4-imidazolecarboxyamide;   Formula=C4H6N4O;   InChI=1S/C4H6N4O/c5-3-2(4(6)9)7-1-8-3/h1H,5H2,(H2,6,9)(H,7,8);   InChIKey=DVNYTAVYBRSTGK-UHFFFAOYSA-N;   SMILES=NC(=O)c1nc[nH]c1N
 alt_id: CHEBI:20544
 xref: Drug_Central:1994;   HMDB:HMDB0003192;   KEGG:C04051
 xref_mesh: MESH:D000620
 xref: MetaCyc:CPD-3762;   PDBeChem:5AC;   PMID:12997251;   PMID:24402866;   Reaxys:3938


show annotations for term's descendants           Sort by:
 
5-aminoimidazole-4-carboxamide term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arg1 arginase 1 multiple interactions
increases expression
EXP Aminoimidazole Carboxamide analog promotes the reaction [Lipopolysaccharides results in increased expression of ARG1 protein]
Aminoimidazole Carboxamide analog results in increased expression of ARG1 protein
CTD PMID:19853624 NCBI chr 1:21,525,421...21,537,872
Ensembl chr 1:21,525,421...21,537,863
JBrowse link
G Il10 interleukin 10 increases expression
multiple interactions
EXP Aminoimidazole Carboxamide analog results in increased expression of IL10 protein
Aminoimidazole Carboxamide analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; dorsomorphin inhibits the reaction [Aminoimidazole Carboxamide analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]]
CTD PMID:19853624 NCBI chr13:47,738,933...47,743,392
Ensembl chr13:47,739,526...47,743,392
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP Aminoimidazole Carboxamide analog promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; dorsomorphin inhibits the reaction [Aminoimidazole Carboxamide promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]] CTD PMID:19853624 NCBI chr 3:121,876,256...121,882,637
Ensembl chr 3:121,876,263...121,882,726
JBrowse link
G Il6 interleukin 6 multiple interactions EXP Aminoimidazole Carboxamide analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:19853624 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP Aminoimidazole Carboxamide analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:19853624 NCBI chr10:66,188,290...66,221,621
Ensembl chr10:66,189,786...66,313,190
JBrowse link
G Ppargc1a PPARG coactivator 1 alpha multiple interactions EXP [Aminoimidazole Carboxamide analog co-treated with Lipopolysaccharides] results in increased expression of PPARGC1A protein; Aminoimidazole Carboxamide analog promotes the reaction [Lipopolysaccharides results in increased expression of PPARGC1A protein]; dorsomorphin inhibits the reaction [Aminoimidazole Carboxamide analog promotes the reaction [Lipopolysaccharides results in increased expression of PPARGC1A protein]] CTD PMID:19853624 NCBI chr14:63,095,291...63,190,688
Ensembl chr14:63,095,720...63,187,009
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP [Aminoimidazole Carboxamide analog co-treated with Lipopolysaccharides] results in increased expression of RELA protein; Aminoimidazole Carboxamide analog inhibits the reaction [Lipopolysaccharides results in increased expression of RELA protein] CTD PMID:19853624 NCBI chr 1:220,992,770...221,003,249
Ensembl chr 1:220,992,770...221,003,249
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP [Lipopolysaccharides co-treated with Aminoimidazole Carboxamide analog] results in increased expression of TGFB1 protein CTD PMID:19853624 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor multiple interactions
increases expression
EXP [dorsomorphin co-treated with Aminoimidazole Carboxamide analog] inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Aminoimidazole Carboxamide inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]
Aminoimidazole Carboxamide analog results in increased expression of TNF protein
CTD PMID:19853624 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19787
    chemical entity 19787
      atom 19784
        nonmetal atom 19659
          nitrogen atom 18542
            nitrogen molecular entity 18542
              organonitrogen compound 18312
                carboxamide 17134
                  monocarboxylic acid amide 14553
                    5-aminoimidazole-4-carboxamide 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19787
    subatomic particle 19784
      composite particle 19784
        hadron 19784
          baryon 19784
            nucleon 19784
              atomic nucleus 19784
                atom 19784
                  main group element atom 19672
                    p-block element atom 19672
                      carbon group element atom 19574
                        carbon atom 19563
                          organic molecular entity 19563
                            organic group 18495
                              organic divalent group 18488
                                organodiyl group 18488
                                  carbonyl group 18391
                                    carbonyl compound 18391
                                      carboxylic acid 18061
                                        carboacyl group 17348
                                          univalent carboacyl group 17348
                                            carbamoyl group 17134
                                              carboxamide 17134
                                                monocarboxylic acid amide 14553
                                                  5-aminoimidazole-4-carboxamide 9
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.