.
HC toxin - Ontology Report - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)

CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:HC toxin
go back to main search page
Accession:CHEBI:48028 term browser browse the term
Definition:A homodetic cyclic tetrapeptide made up from L-alanyl, D-alanyl, L-prolyl and 2-amino-8-oxo-9,10-epoxydecanoyl residues.
Synonyms:related_synonym: Cyclo(2-amino-8-oxo-9,10-epoxydecanoic acid-prolyl-alanyl-alanine);   Cyclo(aoe-pro-ala-ala);   Formula=C21H32N4O6;   InChI=1S/C21H32N4O6/c1-12-18(27)22-13(2)19(28)24-14(7-4-3-5-9-16(26)17-11-31-17)21(30)25-10-6-8-15(25)20(29)23-12/h12-15,17H,3-11H2,1-2H3,(H,22,27)(H,23,29)(H,24,28)/t12-,13+,14-,15+,17?/m0/s1;   InChIKey=GNYCTMYOHGBSBI-KVUCBBCISA-N;   SMILES=[H][C@]12CCCN1C(=O)[C@H](CCCCCC(=O)C1CO1)NC(=O)[C@@H](C)NC(=O)[C@H](C)NC2=O
 xref: CAS:83209-65-8;   KEGG:C15676
 xref_mesh: MESH:C037654
 xref: PMID:10671527;   PMID:12297630;   PMID:15283467;   PMID:16839576;   PMID:18074352;   PMID:18230731;   PMID:18262346;   PMID:19737099;   PMID:3918884;   PMID:9917303;   Patent:EP2194061;   Reaxys:4729824

1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
X

show annotations for term's descendants           Sort by:
HC toxin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gldc glycine decarboxylase increases expression ISO HC toxin results in increased expression of GLDC mRNA CTD PMID:33770205 NCBI chr 1:237,296,753...237,375,620
Ensembl chr 1:227,883,249...227,962,097 		JBrowse link
G Gpr183 G protein-coupled receptor 183 decreases expression ISO HC toxin results in decreased expression of GPR183 mRNA CTD PMID:33770205 NCBI chr15:105,445,129...105,457,192
Ensembl chr15:99,036,367...99,050,559 		JBrowse link
G Idi1 isopentenyl-diphosphate delta isomerase 1 increases expression ISO HC toxin results in increased expression of IDI1 mRNA CTD PMID:33770205 NCBI chr17:66,539,761...66,547,524
Ensembl chr17:61,629,594...61,637,357 		JBrowse link
G Klhl42 kelch-like family, member 42 decreases expression ISO HC toxin results in decreased expression of KLHL42 mRNA CTD PMID:33770205 NCBI chr 4:179,999,655...180,027,283
Ensembl chr 4:180,004,580...180,027,283 		JBrowse link
G Mepce methylphosphate capping enzyme decreases expression ISO HC toxin results in decreased expression of MEPCE mRNA CTD PMID:33770205 NCBI chr12:24,548,596...24,553,315
Ensembl chr12:18,911,796...18,916,514 		JBrowse link
G Nrros negative regulator of reactive oxygen species decreases expression ISO HC toxin results in decreased expression of NRROS mRNA CTD PMID:33770205 NCBI chr11:82,133,608...82,151,160
Ensembl chr11:68,628,712...68,646,142 		JBrowse link
G Ppil1 peptidylprolyl isomerase like 1 decreases expression ISO HC toxin results in decreased expression of PPIL1 mRNA CTD PMID:33770205 NCBI chr20:7,303,919...7,323,962
Ensembl chr20:7,302,621...7,322,354 		JBrowse link
G Srgap3 SLIT-ROBO Rho GTPase activating protein 3 increases expression ISO HC toxin results in increased expression of SRGAP3 mRNA CTD PMID:33770205 NCBI chr 4:147,391,082...147,626,407
Ensembl chr 4:145,840,078...146,070,575 		JBrowse link
G Tmcc2 transmembrane and coiled-coil domain family 2 increases expression ISO HC toxin results in increased expression of TMCC2 mRNA CTD PMID:33770205 NCBI chr13:46,346,177...46,383,862
Ensembl chr13:43,794,029...43,831,716 		JBrowse link
G Tubb2a tubulin, beta 2A class IIa increases expression ISO HC toxin results in increased expression of TUBB2A mRNA CTD PMID:33770205 NCBI chr17:31,002,186...31,006,057
Ensembl chr17:30,747,503...30,800,714 		JBrowse link
G Yes1 YES proto-oncogene 1, Src family tyrosine kinase increases expression ISO HC toxin results in increased expression of YES1 mRNA CTD PMID:33770205 NCBI chr 9:120,646,657...120,753,880
Ensembl chr 9:113,200,256...113,299,837 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19887
    role 19858
      biological role 19856
        biochemical role 19566
          metabolite 19554
            HC toxin 11
Path 2
Term Annotations click to browse term
  CHEBI ontology 19887
    subatomic particle 19885
      composite particle 19885
        hadron 19885
          baryon 19885
            nucleon 19885
              atomic nucleus 19885
                atom 19885
                  main group element atom 19824
                    p-block element atom 19824
                      carbon group element atom 19763
                        carbon atom 19760
                          organic molecular entity 19760
                            heteroorganic entity 19521
                              organochalcogen compound 19282
                                organooxygen compound 19197
                                  carbon oxoacid 18676
                                    carboxylic acid 18673
                                      carboacyl group 17700
                                        univalent carboacyl group 17700
                                          carbamoyl group 17545
                                            carboxamide 17545
                                              peptide 11445
                                                cyclic peptide 8926
                                                  homodetic cyclic peptide 8403
                                                    HC toxin 11
paths to the root