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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:phenothrin
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Accession:CHEBI:34916 term browser browse the term
Definition:A cyclopropanecarboxylate ester that has formula C23H26O3.
Synonyms:exact_synonym: 3-phenoxybenzyl 2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate
 related_synonym: 2,2-Dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid (3-phenoxyphenyl)methyl ester;   Formula=C23H26O3;   InChI=1S/C23H26O3/c1-16(2)13-20-21(23(20,3)4)22(24)25-15-17-9-8-12-19(14-17)26-18-10-6-5-7-11-18/h5-14,20-21H,15H2,1-4H3;   InChIKey=SBNFWQZLDJGRLK-UHFFFAOYSA-N;   SMILES=CC(C)=CC1C(C(=O)OCc2cccc(Oc3ccccc3)c2)C1(C)C;   Sumithrin
 xref: Beilstein:2160930;   CAS:26002-80-2;   Drug_Central:4686;   KEGG:C14387;   KEGG:D08357;   LINCS:LSM-4363
 xref_mesh: MESH:C006166
 xref: PPDB:517;   VSDB:517


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phenothrin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 decreases expression
affects binding		 ISO phenothrin results in decreased expression of ESR1 protein
phenothrin binds to ESR1 protein		 CTD PMID:15118252 PMID:32278787 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002 		JBrowse link
G Esr2 estrogen receptor 2 decreases expression ISO phenothrin results in decreased expression of ESR2 protein CTD PMID:15118252 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919 		JBrowse link
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 multiple interactions ISO phenothrin inhibits the reaction [pregna-4,17-diene-3,16-dione results in decreased activity of NR1H4 protein] CTD PMID:25257666 NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047 		JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions EXP phenothrin binds to and results in increased activity of NR1I2 protein CTD PMID:31538121 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions ISO
EXP		 phenothrin affects the localization of and results in increased activity of NR1I3 protein
phenothrin binds to and results in decreased activity of NR1I3 protein		 CTD PMID:30247703 PMID:31538121 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906 		JBrowse link
G Tff1 trefoil factor 1 multiple interactions
increases expression		 ISO ICI 164384 inhibits the reaction [phenothrin results in increased expression of TFF1 mRNA] CTD PMID:10064545 PMID:15118252 NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597 		JBrowse link
G Vdr vitamin D receptor affects binding ISO phenothrin binds to VDR protein CTD PMID:32278787 NCBI chr 7:128,987,981...129,037,677
Ensembl chr 7:128,987,981...129,037,677 		JBrowse link
G Wnt10b Wnt family member 10B increases expression ISO phenothrin results in increased expression of WNT10B mRNA CTD PMID:12437293 NCBI chr 7:129,922,088...129,927,892
Ensembl chr 7:129,922,088...129,927,892 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19808
    role 19784
      application 19627
        pesticide 17897
          insecticide 16498
            pyrethroid insecticide 3386
              pyrethroid ester insecticide 3384
                phenothrin 8
                  (1R)-trans-phenothrin 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      monocarboxylic acid 17984
                                        cyclopropanecarboxylic acid 2223
                                          chrysanthemic acid 506
                                            phenothrin 8
                                              (1R)-trans-phenothrin 0
paths to the root