The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
A monoterpenoid indole alkaloid with formula C21H24N2O3, isolated from several Rauvolfia and Catharanthus species. It is a selective alpha1-adrenoceptor antagonist used for the treatment of high blood pressure.
raubasine results in increased expression of CASP3 protein CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein]; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein]
raubasine results in increased expression of IL1B protein raubasine results in increased secretion of IL1B protein [Acetylcysteine co-treated with raubasine] results in increased secretion of IL1B protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL1B protein]
raubasine results in increased expression of IL6 protein raubasine results in increased secretion of IL6 protein [Acetylcysteine co-treated with raubasine] results in increased secretion of IL6 protein; CASP3 protein affects the reaction [raubasine results in increased secretion of IL6 protein]
raubasine results in increased secretion of TNF protein [Acetylcysteine co-treated with raubasine] results in increased secretion of TNF protein; CASP3 protein affects the reaction [raubasine results in increased secretion of TNF protein] raubasine results in increased expression of TNF protein