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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Macrosphelide B
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Accession:CHEBI:212207 term browser browse the term
Synonyms:exact_synonym: (7E,13E)-9-hydroxy-4,10,16-trimethyl-1,5,11-trioxacyclohexadeca-7,13-diene-2,6,12,15-tetrone
 related_synonym: Formula=C16H20O8;   InChI=1S/C16H20O8/c1-9-8-16(21)24-11(3)13(18)5-7-15(20)23-10(2)12(17)4-6-14(19)22-9/h4-7,9-12,17H,8H2,1-3H3/b6-4+,7-5+;   InChIKey=BUJQDSFTDISLDT-YDFGWWAZSA-N;   SMILES=O=C1OC(C(O)C=CC(=O)OC(C)CC(OC(C(C=C1)=O)C)=O)C
 xref: Chemspider:7973776
 xref_mesh: MESH:C097799


show annotations for term's descendants           Sort by:
Macrosphelide B term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 increases expression
multiple interactions		 ISO macrosphelide B results in increased expression of HMOX1 protein
NFE2L2 protein affects the reaction [macrosphelide B results in increased expression of HMOX1 protein]		 CTD PMID:37777167 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079 		JBrowse link
G Il6 interleukin 6 multiple interactions ISO macrosphelide B inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein] CTD PMID:37777167 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 affects localization
multiple interactions		 ISO macrosphelide B affects the localization of NFE2L2 protein
NFE2L2 protein affects the reaction [macrosphelide B results in increased expression of HMOX1 protein]		 CTD PMID:37777167 NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737 		JBrowse link
G Nfkbia NFKB inhibitor alpha multiple interactions ISO macrosphelide B inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of NFKBIA protein] CTD PMID:37777167 NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941 		JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO macrosphelide B inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein] CTD PMID:37777167 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210 		JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO macrosphelide B inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein] CTD PMID:37777167 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484 		JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO macrosphelide B inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein] CTD PMID:37777167 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19848
    chemical entity 19846
      atom 19846
        nonmetal atom 19784
          oxygen atom 19527
            oxygen molecular entity 19527
              organooxygen compound 19175
                polyketide 11518
                  macrolide 7533
                    Macrosphelide B 7
Path 2
Term Annotations click to browse term
  CHEBI ontology 19848
    subatomic particle 19846
      composite particle 19846
        hadron 19846
          baryon 19846
            nucleon 19846
              atomic nucleus 19846
                atom 19846
                  main group element atom 19796
                    p-block element atom 19796
                      carbon group element atom 19741
                        carbon atom 19737
                          organic molecular entity 19737
                            heteroorganic entity 19495
                              organochalcogen compound 19257
                                organooxygen compound 19175
                                  ester 17461
                                    carboxylic ester 16732
                                      lactone 13235
                                        macrocyclic lactone 7585
                                          macrolide 7533
                                            Macrosphelide B 7
paths to the root