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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Luteolin 7-methyl ether
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Accession:CHEBI:168675 term browser browse the term
Synonyms:exact_synonym: 2-(3,4-dihydroxyphenyl)-5-hydroxy-7-methoxychromen-4-one
 related_synonym: Formula=C16H12O6;   InChI=1S/C16H12O6/c1-21-9-5-12(19)16-13(20)7-14(22-15(16)6-9)8-2-3-10(17)11(18)4-8/h2-7,17-19H,1H3;   InChIKey=RRRSSAVLTCVNIQ-UHFFFAOYSA-N;   SMILES=O1C=2C(C(=O)C=C1C3=CC(O)=C(O)C=C3)=C(O)C=C(OC)C2
 xref: CAS:20243-59-8;   Chemspider:4476827;   HMDB:HMDB0037339;   LIPID_MAPS_instance:LMPK12111045
 xref_mesh: MESH:C051414
 xref: PDBeChem:6B5
 cyclic_relationship: is_conjugate_acid_of CHEBI:192705


show annotations for term's descendants           Sort by:
Luteolin 7-methyl ether term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bak1 BCL2-antagonist/killer 1 increases expression EXP hydroxygenkwanin results in increased expression of BAK1 protein CTD PMID:24144774 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression EXP hydroxygenkwanin results in decreased expression of BAX protein CTD PMID:24144774 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2l1 Bcl2-like 1 decreases expression EXP hydroxygenkwanin results in decreased expression of BCL2L1 protein CTD PMID:24144774 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP hydroxygenkwanin results in increased expression of BID protein CTD PMID:24144774 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp3 caspase 3 increases activity
multiple interactions		 EXP hydroxygenkwanin results in increased activity of CASP3 protein
Apigenin promotes the reaction [hydroxygenkwanin results in increased activity of CASP3 protein]; hydroxygenkwanin promotes the reaction [Apigenin results in increased activity of CASP3 protein]		 CTD PMID:24144774 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648 		JBrowse link
G Casp8 caspase 8 multiple interactions
increases activity		 EXP Apigenin promotes the reaction [hydroxygenkwanin results in increased activity of CASP8 protein]; hydroxygenkwanin promotes the reaction [Apigenin results in increased activity of CASP8 protein] CTD PMID:24144774 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP
ISO		 hydroxygenkwanin results in decreased activity of CYP1A2 protein CTD PMID:34843882 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312 		JBrowse link
G Cyp2c11 cytochrome P450, subfamily 2, polypeptide 11 decreases activity EXP hydroxygenkwanin results in decreased activity of CYP2C11 protein CTD PMID:34843882 NCBI chr 1:236,762,719...236,799,069
Ensembl chr 1:236,762,842...236,799,066 		JBrowse link
G Tnf tumor necrosis factor increases expression
multiple interactions		 EXP hydroxygenkwanin results in increased expression of TNF protein
Apigenin promotes the reaction [hydroxygenkwanin results in increased expression of TNF protein]; hydroxygenkwanin promotes the reaction [Apigenin results in increased expression of TNF protein]		 CTD PMID:24144774 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19921
    chemical entity 19919
      atom 19919
        nonmetal atom 19848
          carbon atom 19801
            organic molecular entity 19801
              flavonoids 11629
                Luteolin 7-methyl ether 9
Path 2
Term Annotations click to browse term
  CHEBI ontology 19921
    subatomic particle 19919
      composite particle 19919
        hadron 19919
          baryon 19919
            nucleon 19919
              atomic nucleus 19919
                atom 19919
                  main group element atom 19865
                    p-block element atom 19865
                      carbon group element atom 19804
                        carbon atom 19801
                          organic molecular entity 19801
                            heteroorganic entity 19558
                              organochalcogen compound 19317
                                organooxygen compound 19233
                                  ether 17330
                                    Luteolin 7-methyl ether 9
paths to the root