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Genes search result for Rattus norvegicus
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95 records found for search term Fas
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
619831FasFas cell surface death receptorENCODES a protein that exhibits protease binding; protein phosphatase binding; protein-containing complex binding; INVOLVED IN apoptotic signaling pathway; cellular response to cobalt ion; cellular response to cytokine stimulus; PARTICIPATES IN extrinsic apoptotic pathway; Fas1241212155241245774Rat1270symbol , old_gene_name , PhenoGen , name , description , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
3880FaslgFas ligandENCODES a protein that exhibits death receptor binding; tumor necrosis factor receptor binding; cytokine activity (ortholog); INVOLVED IN cellular response to type II interferon; endosomal lumen acidification; extrinsic apoptotic signaling pathway via death domain receptors; PARTICIPATES IN extrinsi137668088576706042Rat760symbol , old_gene_name , PhenoGen , name , description , old_gene_symbolgene, protein-coding, PROVISIONAL [RefSeq]
1310662Fbf1Fas binding factor 1INVOLVED IN apical junction assembly (ortholog); cilium assembly (ortholog); establishment of epithelial cell polarity (ortholog); FOUND IN apical junction complex (ortholog); centriole (ortholog); centrosome (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; amphetami10101874661101900497Rat81old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
70987Faf1Fas associated factor 1ENCODES a protein that exhibits heat shock protein binding (ortholog); NF-kappaB binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN Fas signaling pathway (ortholog); negative regulation of canonical NF-kappaB signal transduction (ortholo5129654677130018604Rat145old_gene_name , name , descriptiongene, protein-coding, VALIDATED [RefSeq]
628700FaddFas associated via death domainENCODES a protein that exhibits death receptor binding; protease binding; protein-containing complex binding; INVOLVED IN behavioral response to cocaine; kidney development; regulation of necroptotic process; PARTICIPATES IN ceramide signaling pathway; FasL medi1209169245209175423Rat432old_gene_name , name , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620572FaimFas apoptotic inhibitory moleculeINVOLVED IN positive regulation of canonical NF-kappaB signal transduction; positive regulation of neurogenesis; negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-c8108423259108445365Rat87old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
628744Faim2Fas apoptotic inhibitory molecule 2INVOLVED IN cerebellar granular layer development (ortholog); cerebellar Purkinje cell differentiation (ortholog); cerebellar Purkinje cell layer development (ortholog); PARTICIPATES IN FasL mediated signaling pathway; ASSOCIATED WITH chronic obstructive pulmona7132512095132539192Rat117name , descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1306577Faf2Fas associated factor family member 2ENCODES a protein that exhibits lipase binding (ortholog); lipase inhibitor activity (ortholog); protein-macromolecule adaptor activity (ortholog); INVOLVED IN ERAD pathway (ortholog); lipid droplet organization (ortholog); proteasome-mediated ubiquitin-dependent protein catabolic process (ortholog)1799523299994596Rat97old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1311601FastkFas-activated serine/threonine kinaseENCODES a protein that exhibits protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation (ortholog); regulation of RNA splicing (ortholog); FOUND IN mitochondrion (ortholog); nuclear speck (ortholog); INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether41162469711628769Rat107symbol , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1590301FaimlFas apoptotic inhibitory molecule likeINVOLVED IN apoptotic process (inferred); negative regulation of apoptotic process (inferred); regulation of signal transduction (inferred); FOUND IN cytoplasm (inferred); INTERACTS WITH bis(2-ethylhexyl) phthalate (ortholog)8108671391108689538Rat5old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
2306872FaslgTn(sb-T2/Bart3)2.325McwiFas ligand (TNF superfamily, member 6); transposon insertion 2.324, Medical College of WisconsinThis mutation consists of an insertion of a Sleeping Beauty transposable element gene trap construct into the 1st intron of the Faslg gene.Ratsymbol , name , description , old_gene_symbolgene, allele
620665Fasnfatty acid synthaseENCODES a protein that exhibits [acyl-carrier-protein] S-malonyltransferase activity; fatty acid synthase activity; identical protein binding; INVOLVED IN acetyl-CoA metabolic process; fatty acid biosynthetic process; response to nutrient; PARTICIPATES IN fatty acid biosynthetic pathway; insulin sig10106570415106588581Rat1027symbol , old_gene_name , PhenoGengene, protein-coding, PROVISIONAL [RefSeq]
1359282FcmrFc mu receptorENCODES a protein that exhibits high-affinity IgM receptor activity (ortholog); IgM binding (ortholog); polymeric immunoglobulin binding (ortholog); INVOLVED IN Fc receptor-mediated immune complex endocytosis (ortholog); humoral immune response mediated by circulating immunoglobulin (ortholog); immu134488962844903926Rat121old_gene_namegene, protein-coding, VALIDATED [RefSeq]
621227Daxxdeath-domain associated proteinENCODES a protein that exhibits JUN kinase binding; kinesin binding; nuclear androgen receptor binding; INVOLVED IN cellular response to hydrogen peroxide; cellular response to tumor necrosis factor; cellular response to type II interferon; PARTICIPATES IN aldosterone signaling pathway; histone modi2049719734978062Rat317old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1563531Fastkd1FAST kinase domains 1INVOLVED IN mitochondrial RNA metabolic process (ortholog); regulation of mitochondrial mRNA stability (ortholog); ASSOCIATED WITH Glaucoma 1, Open Angle, B (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 17beta-estradiol; 6-propyl-2-thiouracil; amitrole37485753974883483Rat59symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1307883Fastkd2FAST kinase domains 2ENCODES a protein that exhibits rRNA binding (ortholog); INVOLVED IN apoptotic process (ortholog); mitochondrial large ribosomal subunit assembly (ortholog); mitochondrial RNA modification (ortholog); ASSOCIATED WITH combined oxidative phosphorylation deficiency 44 (ortholog); cytochrome-c oxidase d97265996172681986Rat116symbol , old_gene_name , PhenoGen , namegene, protein-coding, VALIDATED [RefSeq]
1309729Fastkd3FAST kinase domains 3INVOLVED IN mitochondrial respiratory chain complex IV assembly (ortholog); positive regulation of mitochondrial translation (ortholog); regulation of mitochondrial mRNA stability (ortholog); FOUND IN mitochondrion (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil; 13668672736695376Rat68symbol , old_gene_name , PhenoGen , namegene, protein-coding, PROVISIONAL [RefSeq]
1563839Fastkd5FAST kinase domains 5ENCODES a protein that exhibits rRNA binding (ortholog); INVOLVED IN mitochondrial RNA processing (ortholog); ASSOCIATED WITH schizophrenia (ortholog); FOUND IN mitochondrial nucleoid (ortholog); mitochondrion (ortholog); ribonucleoprotein granule (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenz3138283315138300803Rat46symbol , old_gene_name , PhenoGen , name , old_gene_symbolgene, protein-coding, VALIDATED [RefSeq]
1583309Fscn1fascin actin-bundling protein 1ENCODES a protein that exhibits actin binding; actin filament binding (ortholog); INVOLVED IN actin filament bundle assembly; cellular response to cell-matrix adhesion; liver development; PARTICIPATES IN protein kinase C (PKC) signaling pathway; ASSOCIATED WITH basal cell carcinoma (ortholog); Bile 121671060116723734Rat305old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
1308941Fscn2fascin actin-bundling protein 2, retinalENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN eye photoreceptor cell development (ortholog); ASSOCIATED WITH auditory system disease (ortholog); fundus dystrophy (ortholog); Leber congenital10106121038106139683Rat78old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1303047Fscn3fascin actin-bundling protein 3ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); protein-macromolecule adaptor activity (inferred); INVOLVED IN actin filament organization (inferred); spermatid development (inferred); ASSOCIATED WITH hypospadias (ortholog); FOUND IN cytoplasm (ortholog);45800812458017674Rat57old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
1305771Casp8ap2caspase 8 associated protein 2ENCODES a protein that exhibits cysteine-type endopeptidase activator activity involved in apoptotic process (ortholog); identical protein binding (ortholog); protease binding (ortholog); INVOLVED IN cellular response to mechanical stimulus (ortholog); extrinsic apoptotic signaling pathway via death55180936651848633Rat132descriptiongene, protein-coding, VALIDATED [RefSeq]
1359409Tmbim1transmembrane BAX inhibitor motif containing 1ENCODES a protein that exhibits death receptor binding (ortholog); INVOLVED IN negative regulation of catalytic activity (ortholog); negative regulation of extrinsic apoptotic signaling pathway via death domain receptors (ortholog); negative regulation of Fas si98332097283338469Rat122descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1311973Tnnc2troponin C2, fast skeletal typeENCODES a protein that exhibits actin binding (ortholog); INVOLVED IN regulation of muscle contraction (ortholog); skeletal muscle contraction (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharm3173932611173935339Rat148old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
62050Tnni2troponin I2, fast skeletal typeENCODES a protein that exhibits actin binding (ortholog); troponin T binding (ortholog); INVOLVED IN relaxation of skeletal muscle; positive regulation of DNA-templated transcription (ortholog); skeletal muscle contraction (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic b1206882358207027034Rat167old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
3883Tnnt3troponin T3, fast skeletal typeENCODES a protein that exhibits actin binding (ortholog); calcium-dependent protein binding (ortholog); tropomyosin binding (ortholog); INVOLVED IN regulation of striated muscle contraction; positive regulation of calcium-dependent ATPase activity (ortholog); regulation of ATP-dependent activity (or1207082014207099014Rat158old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
619708Fez1fasciculation and elongation protein zeta 1ENCODES a protein that exhibits protein kinase C binding; gamma-tubulin binding (ortholog); INVOLVED IN cellular response to growth factor stimulus; establishment of cell polarity; establishment of mitochondrion localization; PARTICIPATES IN mitochondria transport pathway; ASSOCIATED WITH Parkinson'84473328844778519Rat164old_gene_name , namegene, protein-coding, PROVISIONAL [RefSeq]
619709Fez2fasciculation and elongation protein zeta 2INVOLVED IN negative regulation of autophagosome assembly (ortholog); ASSOCIATED WITH Myocardial Ischemia (ortholog); Weight Gain (ortholog); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene62240668522446745Rat94old_gene_name , namegene, protein-coding, VALIDATED [RefSeq]
1303131Ncam2neural cell adhesion molecule 2ENCODES a protein that exhibits identical protein binding (ortholog); INVOLVED IN axonal fasciculation; PARTICIPATES IN prion disease pathway; ASSOCIATED WITH amenorrhea (ortholog); FOUND IN axon (ortholog); plasma membrane (ortholog); synaptic membrane (ortholo113359174834078788Rat93old_gene_name , descriptiongene, protein-coding, VALIDATED [RefSeq]
620885Myl1_v2myosin, light chain 1, variant 2ENCODES an splice that exhibits structural constituent of muscle (ortholog); INVOLVED IN muscle contraction (inferred); FOUND IN myosin complex (inferred)Rat8old_gene_namegene, splice
1598796Myl1myosin, light chain 1ENCODES a protein that exhibits structural constituent of muscle (ortholog); INVOLVED IN cardiac muscle contraction; muscle contraction (ortholog); ASSOCIATED WITH congenital myopathy 14 (ortholog); Heart Injuries (ortholog); FOUND IN contractile muscle fiber; myofibril (ortholog); INTERACTS WITH (RRat115old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3177Ngfrnerve growth factor receptorENCODES a protein that exhibits amyloid-beta binding; identical protein binding; nerve growth factor binding; INVOLVED IN cellular response to oxidative stress; negative regulation of angiogenesis; negative regulation of apoptotic process; PARTICIPATES IN cytokine mediated signaling pathway; neurotr108101207781030305Rat526old_gene_namegene, protein-coding, VALIDATED [RefSeq]
3141Myl11myosin light chain 11ENCODES a protein that exhibits structural constituent of muscle (ortholog); INVOLVED IN immune response; skeletal muscle tissue development; muscle contraction (ortholog); ASSOCIATED WITH Desbuquois dysplasia (ortholog); distal arthrogryposis (ortholog); distal arthrogryposis type 1C (ortholog); FO1191257432191263046Rat77old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1311596Mybpc2myosin binding protein C2ENCODES a protein that exhibits actin binding (inferred); INVOLVED IN cardiac muscle contraction (inferred); cell adhesion (inferred); ASSOCIATED WITH Contracture (ortholog); FOUND IN myosin filament (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouraci1104130642104154101Rat73old_gene_namegene, protein-coding, VALIDATED [RefSeq]
1309737Tbrg4transforming growth factor beta regulator 4INVOLVED IN mitochondrial mRNA processing (ortholog); mRNA metabolic process (ortholog); regulation of mitochondrial mRNA stability (ortholog); FOUND IN mitochondrial matrix (ortholog); mitochondrion (ortholog); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,4-dinitrotoluene148569673885704691Rat108old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
1586677Casq1calsequestrin 1ENCODES a protein that exhibits calcium ion binding (ortholog); identical protein binding (ortholog); INVOLVED IN response to denervation involved in regulation of muscle adaptation; response to muscle inactivity; skeletal muscle tissue development; PARTICIPATES IN calcium/calcium-mediated signaling138720302187212710Rat132old_gene_namegene, protein-coding, VALIDATED [RefSeq]
619998Tmem150atransmembrane protein 150AINVOLVED IN catabolic process; phosphatidylinositol phosphate biosynthetic process (ortholog); protein localization to plasma membrane (ortholog); FOUND IN plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine4105968526105972822Rat88old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
3786Abcc8ATP binding cassette subfamily C member 8ENCODES a protein that exhibits ADP binding (ortholog); ATP binding (ortholog); ATPase-coupled monoatomic cation transmembrane transporter activity (ortholog); INVOLVED IN female pregnancy; intracellular glucose homeostasis; memory; PARTICIPATES IN diabetes mellitus pathway; acebutolol pharmacodynam1105734992105816272Rat401descriptiongene, protein-coding, VALIDATED [RefSeq]
127285598Abcc8em1CgenATP binding cassette subfamily C member 8; TALEN induced mutant 1, CgenASSOCIATED WITH decreased body weight; decreased fasting circulating glucose level; decreased insulin secretionRat8descriptiongene, allele
1303079Amigo1adhesion molecule with Ig like domain 1ENCODES a protein that exhibits potassium channel regulator activity (ortholog); INVOLVED IN axonal fasciculation; axonogenesis; cellular response to L-glutamate; ASSOCIATED WITH schizophrenia (ortholog); FOUND IN neuronal cell body; pericellular basket; dendrit2198511285198516744Rat113descriptiongene, protein-coding, VALIDATED [RefSeq]
1308738Arhgap35Rho GTPase activating protein 35ENCODES a protein that exhibits GTPase activating protein binding; GTPase activator activity; protein-containing complex binding; INVOLVED IN positive regulation of GTPase activity; axon guidance (ortholog); axonal fasciculation (ortholog); PARTICIPATES IN ephri18633056686447414Rat173descriptiongene, protein-coding, VALIDATED [RefSeq]
620160BidBH3 interacting domain death agonistENCODES a protein that exhibits ubiquitin protein ligase binding (ortholog); INVOLVED IN glial cell apoptotic process; positive regulation of apoptotic process; positive regulation of autophagy in response to ER overload; PARTICIPATES IN FasL mediated signaling 4155785366155808775Rat661descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620690Birc2baculoviral IAP repeat-containing 2ENCODES a protein that exhibits protein-containing complex binding; FBXO family protein binding (ortholog); identical protein binding (ortholog); INVOLVED IN response to bleomycin; response to cAMP; response to ethanol; PARTICIPATES IN FasL mediated signaling pa81325369713273672Rat385descriptiongene, protein-coding, VALIDATED [RefSeq]
621282Birc3baculoviral IAP repeat-containing 3ENCODES a protein that exhibits protein-containing complex binding; transferase activity (ortholog); ubiquitin-protein transferase activity (ortholog); INVOLVED IN spermatogenesis; cellular response to tumor necrosis factor (ortholog); necroptotic process (ortholog); PARTICIPATES IN ceramide signali81328570213313329Rat487descriptiongene, protein-coding, VALIDATED [RefSeq]
1359683BtkBruton tyrosine kinaseENCODES a protein that exhibits protein tyrosine kinase activity; identical protein binding (ortholog); non-membrane spanning protein tyrosine kinase activity (ortholog); INVOLVED IN cellular response to molecule of fungal origin; cellular response to reactive oxygen species; eosinophil homeostasis;X102016070102055448Rat250descriptiongene, protein-coding, VALIDATED [RefSeq]
2275Casp3caspase 3ENCODES a protein that exhibits cysteine-type peptidase activity; death receptor binding; phospholipase A2 activator activity; INVOLVED IN axonal fasciculation; glial cell apoptotic process; hippocampus development; PARTICIPATES IN apoptotic cell death pathway; 165239553952413794Rat5743descriptiongene, protein-coding, VALIDATED [RefSeq]
70967Casp6caspase 6ENCODES a protein that exhibits endopeptidase activity; cysteine-type endopeptidase activity (ortholog); identical protein binding (ortholog); INVOLVED IN acute inflammatory response to non-antigenic stimulus; axonal fasciculation; lens development in camera-typ2221140287221152727Rat377descriptiongene, protein-coding, VALIDATED [RefSeq]
620944Casp7caspase 7ENCODES a protein that exhibits cysteine-type peptidase activity; aspartic-type endopeptidase activity (ortholog); cysteine-type endopeptidase activity (ortholog); INVOLVED IN leukocyte apoptotic process; protein catabolic process; striated muscle cell differentiation; PARTICIPATES IN extrinsic apop1265442647265481938Rat864descriptiongene, protein-coding, VALIDATED [RefSeq]
620945Casp8caspase 8ENCODES a protein that exhibits cysteine-type endopeptidase activity; death receptor binding; protein-containing complex binding; INVOLVED IN positive regulation of neuron apoptotic process; protein processing; response to anesthetic; PARTICIPATES IN FasL mediat96774710967806699Rat1623descriptiongene, protein-coding, VALIDATED [RefSeq]
69280Cdh2cadherin 2ENCODES a protein that exhibits beta-catenin binding; nitric-oxide synthase binding; protein kinase binding; INVOLVED IN calcium-dependent cell-cell adhesion; cell-cell adhesion; modulation of chemical synaptic transmission; PARTICIPATES IN cadherin mediated signaling pathway; fibroblast growth fact1880510978265288Rat715descriptiongene, protein-coding, VALIDATED [RefSeq]
621787Celsr3cadherin, EGF LAG seven-pass G-type receptor 3ENCODES a protein that exhibits calcium ion binding (inferred); G protein-coupled receptor activity (inferred); transmembrane signaling receptor activity (inferred); INVOLVED IN axonal fasciculation (ortholog); cilium assembly (ortholog); dopaminergic neuron axo8118409136118438593Rat128descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620847CflarCASP8 and FADD-like apoptosis regulatorENCODES a protein that exhibits death receptor binding; protease binding; protein-containing complex binding; INVOLVED IN cellular response to dexamethasone stimulus; cellular response to epidermal growth factor stimulus; cellular response to estradiol stimulus; PARTICIPATES IN Fas96767950267747226Rat433descriptiongene, protein-coding, VALIDATED [RefSeq]
1306661Chukcomponent of inhibitor of nuclear factor kappa B kinase complexENCODES a protein that exhibits protein-containing complex binding; identical protein binding (ortholog); IkappaB kinase activity (ortholog); INVOLVED IN response to acetate; response to amino acid; response to cholecystokinin; PARTICIPATES IN adenosine signaling pathway; Fas1252908748252944273Rat474descriptiongene, protein-coding, PROVISIONAL [RefSeq]
2364Cltcclathrin heavy chainENCODES a protein that exhibits ankyrin binding; heat shock protein binding; peptide binding; INVOLVED IN Golgi organization; mitotic cell cycle; receptor-mediated endocytosis; PARTICIPATES IN clathrin-dependent synaptic vesicle endocytosis; FasL mediated signal107201498472073308Rat256descriptiongene, protein-coding, PROVISIONAL [RefSeq]
621085Crtac1cartilage acidic protein 1ENCODES a protein that exhibits calcium ion binding (inferred); INVOLVED IN axonal fasciculation (ortholog); olfactory bulb development (ortholog); regulation of synapse assembly (ortholog); FOUND IN glutamatergic synapse (ortholog); growth cone (ortholog); post1251040963251182920Rat74descriptiongene, protein-coding, VALIDATED [RefSeq]
1562230Ctnna3catenin alpha 3ENCODES a protein that exhibits beta-catenin binding (ortholog); INVOLVED IN bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); cell-cell adhesion (ortholog); regulation of heart rate by cardiac conduction (ortholog); PARTICIPATES IN arrhythmogenic right ventricu202361301625198699Rat106descriptiongene, protein-coding, VALIDATED [RefSeq]
1305794DspdesmoplakinENCODES a protein that exhibits protein kinase C binding (ortholog); scaffold protein binding (ortholog); INVOLVED IN adherens junction organization (ortholog); bundle of His cell-Purkinje myocyte adhesion involved in cell communication (ortholog); cell-cell adhesion (ortholog); PARTICIPATES IN arrh172682915326877419Rat362descriptiongene, protein-coding, VALIDATED [RefSeq]
620391Efna5ephrin A5ENCODES a protein that exhibits ephrin receptor binding; receptor ligand activity; chemorepellent activity (ortholog); INVOLVED IN axonal fasciculation; apoptotic process (ortholog); axon guidance (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectiona9109763786110042396Rat170descriptiongene, protein-coding, VALIDATED [RefSeq]
620831Epha5EPH receptor A5ENCODES a protein that exhibits ephrin receptor activity; growth factor binding; GPI-linked ephrin receptor activity (ortholog); INVOLVED IN axonal fasciculation; dendritic spine morphogenesis; ephrin receptor signaling pathway; PARTICIPATES IN ephrin - ephrin r142400740024374854Rat159descriptiongene, protein-coding, VALIDATED [RefSeq]
1305602Ephb3Eph receptor B3ENCODES a protein that exhibits axon guidance receptor activity (ortholog); ephrin receptor activity (ortholog); INVOLVED IN angiogenesis (ortholog); axon guidance (ortholog); axonal fasciculation (ortholog); PARTICIPATES IN ephrin - ephrin receptor bidirectiona119334509893363775Rat165descriptiongene, protein-coding, VALIDATED [RefSeq]
621161EzrezrinENCODES a protein that exhibits protein domain specific binding; protein-containing complex binding; actin binding (ortholog); INVOLVED IN epithelial cell differentiation; filopodium assembly; actin cytoskeleton organization (ortholog); PARTICIPATES IN FasL medi14937303349416573Rat463descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1311068Fezf2Fez family zinc finger 2ENCODES a protein that exhibits chromatin binding (ortholog); DNA-binding transcription activator activity, RNA polymerase II-specific (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); INVOLVED IN axonal fasciculati151519904515207982Rat119descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620856Gtf2ird1GTF2I repeat domain containing 1ENCODES a protein that exhibits DNA-binding transcription factor activity (ortholog); DNA-binding transcription repressor activity, RNA polymerase II-specific (ortholog); RNA polymerase II cis-regulatory region sequence-specific DNA binding (ortholog); INVOLVED IN negative regulation of transcriptio122789059427997506Rat147descriptiongene, protein-coding, VALIDATED [RefSeq]
1307435Gtf2ird2GTF2I repeat domain containing 2ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN transition between fast and slow fiber (ortholog); FOUND IN nucleoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 6-propyl-2-thiouracil; amitrole; amphetamine122813419928179089Rat65descriptiongene, protein-coding, VALIDATED [RefSeq]
621375Ikbkbinhibitor of nuclear factor kappa B kinase subunit betaENCODES a protein that exhibits ATP binding; IkappaB kinase activity; protein-containing complex binding; INVOLVED IN neuron projection development; obsolete positive regulation of NF-kappaB transcription factor activity; positive regulation of cell population proliferation; PARTICIPATES IN adenosin167602196876075717Rat564descriptiongene, protein-coding, VALIDATED [RefSeq]
735223Ikbkginhibitor of nuclear factor kappa B kinase regulatory subunit gammaENCODES a protein that exhibits peroxisome proliferator activated receptor binding; protein-containing complex binding; identical protein binding (ortholog); INVOLVED IN anoikis (ortholog); B cell homeostasis (ortholog); canonical NF-kappaB signal transduction (ortholog); PARTICIPATES IN FasX157358279157397563Rat281descriptiongene, protein-coding, VALIDATED [RefSeq]
619777L1camL1 cell adhesion moleculeENCODES a protein that exhibits PDZ domain binding; identical protein binding (ortholog); integrin binding (ortholog); INVOLVED IN axonal fasciculation; cellular response to dexamethasone stimulus; cellular response to ethanol; ASSOCIATED WITH abnormal corpus caX156748597156775116Rat325descriptiongene, protein-coding, VALIDATED [RefSeq]
1560043Map2k7mitogen activated protein kinase kinase 7ENCODES a protein that exhibits ATP binding; JUN kinase kinase activity; magnesium ion binding; INVOLVED IN cellular response to osmotic stress; cellular response to sorbitol; JNK cascade; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; adenosine signaling pathway; Fas1273890327398377Rat251descriptiongene, protein-coding, VALIDATED [RefSeq]
3663Mapk10mitogen activated protein kinase 10ENCODES a protein that exhibits ATP binding; JUN kinase activity; INVOLVED IN cellular hyperosmotic response; JNK cascade; JUN phosphorylation; PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; FasL mediated signaling pathway; platelet-derived gro1468022477094103Rat284descriptiongene, protein-coding, REVIEWED [RefSeq]
1309340Mapk11mitogen-activated protein kinase 11ENCODES a protein that exhibits ATP binding; MAP kinase activity; protein serine/threonine kinase activity (ortholog); INVOLVED IN protein phosphorylation; bone development (ortholog); cellular response to interleukin-1 (ortholog); PARTICIPATES IN adenosine signaling pathway; eicosanoid signaling pa7122098120122105023Rat224descriptiongene, protein-coding, PROVISIONAL [RefSeq]
628847Mapk9mitogen-activated protein kinase 9ENCODES a protein that exhibits ATP binding; JUN kinase activity; mitogen-activated protein kinase kinase kinase binding; INVOLVED IN cellular hyperosmotic response; cellular response to amyloid-beta; cellular response to growth factor stimulus; PARTICIPATES IN c-Jun N-terminal kinases MAPK signalin103467075034711972Rat817descriptiongene, protein-coding, REVIEWED [RefSeq]
620934Mylk2myosin light chain kinase 2ENCODES a protein that exhibits myosin light chain binding; myosin light chain kinase activity; INVOLVED IN muscle contraction; positive regulation of fast-twitch skeletal muscle fiber contraction; protein phosphorylation; PARTICIPATES IN calcium/calcium-mediate3161836705161848609Rat139descriptiongene, protein-coding, VALIDATED [RefSeq]
67378Ncam1neural cell adhesion molecule 1ENCODES a protein that exhibits LRR domain binding; phosphatase binding; INVOLVED IN animal organ regeneration; axonal fasciculation; behavioral response to ethanol; PARTICIPATES IN fibroblast growth factor signaling pathway; prion disease pathway; ASSOCIATED WI85876208859062131Rat308descriptiongene, protein-coding, VALIDATED [RefSeq]
1310526Ndnnecdin, MAGE family memberENCODES a protein that exhibits gamma-tubulin binding (ortholog); promoter-specific chromatin binding (ortholog); INVOLVED IN axon extension (ortholog); axonal fasciculation (ortholog); axonogenesis (ortholog); ASSOCIATED WITH Animal Mammary Neoplasms (ortholog)1125261059125262658Rat131descriptiongene, protein-coding, VALIDATED [RefSeq]
1306731Nrapnebulin-related anchoring proteinENCODES a protein that exhibits actin binding (ortholog); muscle alpha-actinin binding (ortholog); vinculin binding (ortholog); ASSOCIATED WITH dilated cardiomyopathy (ortholog); genetic disease (ortholog); Sudden Death (ortholog); FOUND IN fascia adherens (orth1265355324265433229Rat95descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620307Pdpk13-phosphoinositide dependent protein kinase-1ENCODES a protein that exhibits 3-phosphoinositide-dependent protein kinase activity; insulin receptor binding; protein kinase binding; INVOLVED IN cellular response to brain-derived neurotrophic factor stimulus; focal adhesion assembly; negative regulation of neuron apoptotic process; PARTICIPATES 101361000013687226Rat294descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620917Pik3cbphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit betaENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity; 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (ortholog); insulin receptor substrate binding (ortholog); INVOLVED IN phosphatidylinositol phosphate biosynthetic process; angiogenesis involved in wound healing (orth8108474017108579140Rat286descriptiongene, protein-coding, VALIDATED [RefSeq]
1310990Pik3cdphosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit deltaENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase activity (inferred); 1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity (inferred); ATP binding (inferred); INVOLVED IN negative regulation of gene expression; B cell activation (ortholog); B cell homeostasis (ortholog); PARTICIP5165377994165426620Rat295descriptiongene, protein-coding, VALIDATED [RefSeq]
68341Pik3r2phosphoinositide-3-kinase regulatory subunit 2ENCODES a protein that exhibits phosphatidylinositol 3-kinase regulatory subunit binding (ortholog); phosphotyrosine residue binding (ortholog); protein heterodimerization activity (ortholog); INVOLVED IN negative regulation of cell migration involved in sprouting angiogenesis; cellular response to 161869938918708045Rat203descriptiongene, protein-coding, PROVISIONAL [RefSeq]
621042Pik3r3phosphoinositide-3-kinase regulatory subunit 3ENCODES a protein that exhibits 1-phosphatidylinositol-3-kinase regulator activity; phosphotyrosine residue binding (ortholog); INVOLVED IN cell migration involved in sprouting angiogenesis (ortholog); insulin receptor signaling pathway (ortholog); phosphatidylinositol 3-kinase/protein kinase B sign5134936790135009303Rat237descriptiongene, protein-coding, VALIDATED [RefSeq]
3455Ptprz1protein tyrosine phosphatase, receptor type Z1ENCODES a protein that exhibits fibroblast growth factor binding; phosphatase activity; protein tyrosine phosphatase activity; INVOLVED IN axonal fasciculation; hippocampus development; negative regulation of cell population proliferation; ASSOCIATED WITH amyotr45236300652560905Rat223descriptiongene, protein-coding, VALIDATED [RefSeq]
620619Rfc1replication factor C subunit 1ENCODES a protein that exhibits DNA-binding transcription factor binding; double-stranded DNA binding; protein domain specific binding; INVOLVED IN negative regulation of DNA-templated transcription; negative regulation of transcription by RNA polymerase II; positive regulation of DNA-templated tran144331976843395028Rat161descriptiongene, protein-coding, VALIDATED [RefSeq]
1310158Ripk1receptor interacting serine/threonine kinase 1ENCODES a protein that exhibits death receptor binding; protein-containing complex binding; death domain binding (ortholog); INVOLVED IN positive regulation of necroptotic process; positive regulation of neuron apoptotic process; positive regulation of non-canonical NF-kappaB signal transduction; PA173104498331077167Rat464descriptiongene, protein-coding, PROVISIONAL [RefSeq]
620989Rtn4reticulon 4ENCODES a protein that exhibits protein-containing complex binding; cadherin binding (ortholog); lipid binding (ortholog); INVOLVED IN axonal fasciculation; negative regulation of axon extension; negative regulation of axonogenesis; ASSOCIATED WITH Experimental 14107651001107698610Rat353descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1308650Sema5asemaphorin 5AENCODES a protein that exhibits chondroitin sulfate proteoglycan binding; heparan sulfate proteoglycan binding; syndecan binding; INVOLVED IN axonal fasciculation; diencephalon development; negative regulation of axon extension involved in axon guidance; ASSOCIA28502072485451938Rat199descriptiongene, protein-coding, VALIDATED [RefSeq]
1549719Smpd1sphingomyelin phosphodiesterase 1ENCODES a protein that exhibits acid sphingomyelin phosphodiesterase activity (ortholog); phosphatidylcholine phospholipase C activity (ortholog); sphingomyelin phosphodiesterase activity (ortholog); INVOLVED IN ceramide biosynthetic process; positive regulation of apoptotic process; response to coc1169304772169308615Rat254descriptiongene, protein-coding, PROVISIONAL [RefSeq]
3796Sykspleen associated tyrosine kinaseENCODES a protein that exhibits protein domain specific binding; protein kinase activity; protein tyrosine kinase activity; INVOLVED IN positive regulation of mast cell degranulation; protein autophosphorylation; regulation of immune response; PARTICIPATES IN eicosanoid signaling pathway; Fas171275649312830927Rat408descriptiongene, protein-coding, VALIDATED [RefSeq]
727872SynmsyneminENCODES a protein that exhibits intermediate filament binding (ortholog); structural constituent of cytoskeleton (ortholog); structural constituent of muscle (ortholog); INVOLVED IN fast-twitch skeletal muscle fiber contraction (ortholog); FOUND IN intermediate 1130743891130774254Rat167descriptiongene, protein-coding, PROVISIONAL [RefSeq]
1565416Tln2talin 2ENCODES a protein that exhibits actin binding (inferred); actin filament binding (inferred); structural constituent of cytoskeleton (inferred); INVOLVED IN presynaptic actin cytoskeleton organization (ortholog); PARTICIPATES IN integrin mediated signaling pathway; ASSOCIATED WITH myoepithelioma (ort87671211277133361Rat137descriptiongene, protein-coding, VALIDATED [RefSeq]
1307308Tnfrsf21TNF receptor superfamily member 21INVOLVED IN axonal fasciculation; adaptive immune response (ortholog); apoptotic process (ortholog); PARTICIPATES IN cytokine mediated signaling pathway; ASSOCIATED WITH amyotrophic lateral sclerosis (ortholog); Gliosis (ortholog); Prostatic Neoplasms (ortholog)92537640025451323Rat258descriptiongene, protein-coding, PROVISIONAL [RefSeq]
621765Tnni1troponin I1, slow skeletal typeENCODES a protein that exhibits actin binding (inferred); INVOLVED IN transition between fast and slow fiber (ortholog); ventricular cardiac muscle tissue morphogenesis (ortholog); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor ago134978152949793385Rat107descriptiongene, protein-coding, VALIDATED [RefSeq]
1304776Xirp1xin actin-binding repeat containing 1ENCODES a protein that exhibits actin filament binding (ortholog); INVOLVED IN actin filament organization (ortholog); cardiac muscle cell development (ortholog); intracellular protein localization (ortholog); ASSOCIATED WITH hypertrophic cardiomyopathy (ortholog); microcephaly (ortholog); Poisoning8128625111128635011Rat93descriptiongene, protein-coding, VALIDATED [RefSeq]
3138Myh3myosin heavy chain 3ENCODES a protein that exhibits actin filament binding (ortholog); ATP hydrolysis activity (ortholog); microfilament motor activity (ortholog); INVOLVED IN ATP metabolic process (ortholog); skeletal muscle contraction (ortholog); PARTICIPATES IN myocarditis pathway; ASSOCIATED WITH arthrogryposis mu105226918552293000Rat148old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
621293Atp2a1ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1ENCODES a protein that exhibits ATP binding; calcium ion binding; calcium-dependent ATPase activity; INVOLVED IN calcium ion transmembrane transport; calcium ion transport; response to peptide hormone; PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; Alzheimer's1190457198190475410Rat251old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
628822Stab2stabilin 2ENCODES a protein that exhibits hyaluronic acid binding; cargo receptor activity (ortholog); low-density lipoprotein particle binding (ortholog); INVOLVED IN endocytosis; defense response to bacterium (ortholog); defense response to Gram-positive bacterium (ortholog); ASSOCIATED WITH hepatocellular 72313693823342633Rat103old_gene_namegene, protein-coding, VALIDATED [RefSeq]