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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of extrinsic apoptotic signaling pathway in absence of ligand
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Accession:GO:2001239 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of extrinsic apoptotic signaling pathway in absence of ligand.
Synonyms:exact_synonym: regulation of extrinsic apoptotic signalling pathway in absence of ligand
 narrow_synonym: regulation of extrinsic apoptosis in absence of ligand
 related_synonym: regulation of dependence receptor signaling pathway


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regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Fgfr1 Fibroblast growth factor receptor 1 acts_upstream_of_or_within ISO MGI:2176216|MGI:2181474 (PMID:16207751), (PMID:18191119) RGD PMID:16207751 PMID:18191119 NCBI chr16:66,491,930...66,547,161
Ensembl chr16:66,494,042...66,547,350 		JBrowse link
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agap2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr 7:62,897,282...62,914,295
Ensembl chr 7:62,897,282...62,914,295 		JBrowse link
G Bcl2 BCL2, apoptosis regulator acts_upstream_of_or_within
involved_in		 ISO
IEA		 MGI:99702 (PMID:8358790)
GO_REF:0000107		 RGD
Ensembl		 PMID:8358790 GO_REF:0000107 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2l10 Bcl2-like 10 acts_upstream_of_or_within ISO (PMID:9878060) RGD PMID:9878060 NCBI chr 8:76,107,326...76,113,373
Ensembl chr 8:76,107,326...76,113,367 		JBrowse link
G Col2a1 collagen type II alpha 1 chain involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:2152978 (PMID:9299161)		 Ensembl
RGD		 PMID:9299161 GO_REF:0000107 NCBI chr 7:129,098,489...129,127,560
Ensembl chr 7:129,098,786...129,127,546 		JBrowse link
G Csf2 colony stimulating factor 2 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199 		JBrowse link
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Cx3cl1 C-X3-C motif chemokine ligand 1 acts_upstream_of_or_within ISO (PMID:18322241), (PMID:18971423) RGD PMID:18322241 PMID:18971423 NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833 		JBrowse link
G Eya1 EYA transcriptional coactivator and phosphatase 1 involved_in
acts_upstream_of_or_within		 IBA
ISO		 GO_REF:0000033
MGI:1857803 (PMID:15817220)		 GO_Central
RGD		 PMID:15817220 GO_REF:0000033 NCBI chr 5:4,863,501...5,101,483
Ensembl chr 5:4,955,543...5,101,483 		JBrowse link
G Eya2 EYA transcriptional coactivator and phosphatase 2 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 3:154,335,598...154,519,006
Ensembl chr 3:154,335,400...154,518,793 		JBrowse link
G Eya3 EYA transcriptional coactivator and phosphatase 3 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 5:144,806,523...144,934,522
Ensembl chr 5:144,806,577...144,934,518 		JBrowse link
G Eya4 EYA transcriptional coactivator and phosphatase 4 involved_in IBA GO_REF:0000033 GO_Central GO_REF:0000033 NCBI chr 1:22,172,275...22,415,978
Ensembl chr 1:22,172,275...22,415,976 		JBrowse link
G Fgf10 fibroblast growth factor 10 acts_upstream_of_or_within ISO MGI:1859647 (PMID:16956603) RGD PMID:16956603 NCBI chr 2:50,801,171...50,878,218
Ensembl chr 2:50,800,992...50,876,866 		JBrowse link
G Fyn FYN proto-oncogene, Src family tyrosine kinase involved_in IMP PMID:18469807 UniProt PMID:18469807 RGD:8553892 NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911 		JBrowse link
G Gas1 growth arrest-specific 1 acts_upstream_of_or_within ISO (PMID:15070677) RGD PMID:15070677 NCBI chr17:4,482,168...4,485,153 JBrowse link
G Gata1 GATA binding protein 1 involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr  X:14,529,706...14,537,530
Ensembl chr  X:14,529,702...14,537,530 		JBrowse link
G Gdnf glial cell derived neurotrophic factor involved_in ISO
IEA		 (PMID:10921886)
GO_REF:0000107		 RGD
Ensembl		 PMID:10921886 GO_REF:0000107 NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209 		JBrowse link
G Gfral GDNF family receptor alpha like involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:16086688)		 Ensembl
RGD		 PMID:16086688 GO_REF:0000107 NCBI chr 8:76,917,894...76,963,258
Ensembl chr 8:76,918,657...76,959,425 		JBrowse link
G Hspa1a heat shock protein family A (Hsp70) member 1A involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227 		JBrowse link
G Hspa1b heat shock protein family A (Hsp70) member 1B involved_in ISO (PMID:17167422) RGD PMID:17167422 NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240 		JBrowse link
G Il1b interleukin 1 beta involved_in ISO (PMID:10748004) RGD PMID:10748004 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il7 interleukin 7 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:8950980)		 Ensembl
RGD		 PMID:8950980 GO_REF:0000107 NCBI chr 2:94,235,219...94,280,075
Ensembl chr 2:94,234,766...94,280,075 		JBrowse link
G Map2k5 mitogen activated protein kinase kinase 5 involved_in IMP PMID:20551324 BHF-UCL PMID:20551324 RGD:8553940 NCBI chr 8:63,625,220...63,852,090
Ensembl chr 8:63,625,221...63,851,983 		JBrowse link
G Mapk7 mitogen-activated protein kinase 7 involved_in ISO
IEA		 UniProtKB:Q62862 (PMID:20551324)
GO_REF:0000107		 RGD
Ensembl		 PMID:20551324 GO_REF:0000107 NCBI chr10:46,170,264...46,176,262
Ensembl chr10:46,170,167...46,176,267 		JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member involved_in ISO (PMID:20921992) RGD PMID:20921992 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303 		JBrowse link
G Nrg1 neuregulin 1 involved_in ISO (PMID:9553078) RGD PMID:9553078 NCBI chr16:59,250,658...60,304,519
Ensembl chr16:59,250,854...60,296,884 		JBrowse link
G Pf4 platelet factor 4 involved_in ISO (PMID:10666185) RGD PMID:10666185 NCBI chr14:17,298,304...17,299,220
Ensembl chr14:17,298,308...17,299,365 		JBrowse link
G Prdx2 peroxiredoxin 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:9115640)		 Ensembl
RGD		 PMID:9115640 GO_REF:0000107 NCBI chr19:23,180,927...23,186,217
Ensembl chr19:23,180,930...23,186,194 		JBrowse link
G Ripk1 receptor interacting serine/threonine kinase 1 involved_in ISO (MGI:5306563|PMID:20125124) RGD PMID:20125124 MGI:5306563 NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824 		JBrowse link
G Sgk3 serum/glucocorticoid regulated kinase family, member 3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
(PMID:11050396)		 Ensembl
RGD		 PMID:11050396 GO_REF:0000107 NCBI chr 5:9,345,761...9,472,243
Ensembl chr 5:9,346,040...9,415,476 		JBrowse link
G Snai2 snail family transcriptional repressor 2 acts_upstream_of_or_within ISO (PMID:10518215) RGD PMID:10518215 NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200 		JBrowse link
G Stradb STE20 related adaptor beta acts_upstream_of_or_within ISO (PMID:12574163) RGD PMID:12574163 NCBI chr 9:60,414,182...60,433,084
Ensembl chr 9:60,414,182...60,433,084 		JBrowse link
G Tert telomerase reverse transcriptase involved_in ISO (PMID:10449030) RGD PMID:10449030 NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561 		JBrowse link
G Tnf tumor necrosis factor involved_in ISO (PMID:10666185), (PMID:10748004) RGD PMID:10666185 PMID:10748004 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in ISO
IEA		 (PMID:18469807)
GO_REF:0000107		 RGD
Ensembl		 PMID:18469807 GO_REF:0000107 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Zc3hc1 zinc finger, C3HC-type containing 1 acts_upstream_of_or_within ISO (PMID:12748172) RGD PMID:12748172 NCBI chr 4:58,989,989...59,011,925
Ensembl chr 4:58,989,987...59,011,933 		JBrowse link
positive regulation of extrinsic apoptotic signaling pathway in absence of ligand term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ctnna1 catenin alpha 1 acts_upstream_of_or_within ISO MGI:2677796 (PMID:22411810) RGD PMID:22411810 NCBI chr18:26,728,246...26,860,911
Ensembl chr18:26,728,485...26,860,910 		JBrowse link
G Dapk3 death-associated protein kinase 3 involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr 7:8,524,182...8,532,552
Ensembl chr 7:8,524,183...8,532,558 		JBrowse link
G Htra2 HtrA serine peptidase 2 involved_in ISO (PMID:20125124) RGD PMID:20125124 NCBI chr 4:115,556,914...115,560,202
Ensembl chr 4:115,556,916...115,560,095 		JBrowse link
G Inhba inhibin subunit beta A involved_in ISO
ISS		 (PMID:8267637)
GO_REF:0000024		 RGD
UniProt		 PMID:8267637 GO_REF:0000024 NCBI chr17:49,091,635...49,111,573
Ensembl chr17:49,095,920...49,108,982 		JBrowse link
G Jak3 Janus kinase 3 involved_in ISO (MGI:3719947|PMID:16020505) RGD PMID:16020505 MGI:3719947 NCBI chr16:18,386,330...18,398,542
Ensembl chr16:18,386,405...18,398,536 		JBrowse link
G Nf1 neurofibromin 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 GO_REF:0000107
MGI:1857478 (PMID:15039234)		 Ensembl
RGD		 PMID:15039234 GO_REF:0000107 NCBI chr10:64,306,027...64,539,112
Ensembl chr10:64,306,301...64,536,658 		JBrowse link
G Ppp1ca protein phosphatase 1 catalytic subunit alpha acts_upstream_of_or_within ISO (PMID:12115603) RGD PMID:12115603 NCBI chr 1:201,485,117...201,488,734
Ensembl chr 1:201,485,085...201,497,327 		JBrowse link
G Ppp2r1a protein phosphatase 2 scaffold subunit A alpha acts_upstream_of_or_within ISO (PMID:12944463) RGD PMID:12944463 NCBI chr 1:60,540,223...60,559,467
Ensembl chr 1:60,540,194...60,560,129 		JBrowse link
G Ppp2r1b protein phosphatase 2 scaffold subunit A beta involved_in ISO
IEA		 (PMID:21172653)
GO_REF:0000107		 RGD
Ensembl		 PMID:21172653 GO_REF:0000107 NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485 		JBrowse link
G Ret ret proto-oncogene involved_in ISO (PMID:10921886) RGD PMID:10921886 NCBI chr 4:151,325,969...151,368,176
Ensembl chr 4:151,326,431...151,368,176 		JBrowse link
G Srpx sushi-repeat-containing protein, X-linked acts_upstream_of_or_within ISO MGI:3706175 (PMID:17088259) RGD PMID:17088259 NCBI chr  X:12,676,984...12,751,296
Ensembl chr  X:12,566,645...12,747,882 		JBrowse link
G Tgfb2 transforming growth factor, beta 2 acts_upstream_of_or_within ISO (PMID:8206089) RGD PMID:8206089 NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405 		JBrowse link
G Unc5b unc-5 netrin receptor B involved_in IMP PMID:21172653 UniProt PMID:21172653 RGD:8554227 NCBI chr20:28,697,726...28,764,474
Ensembl chr20:28,697,726...28,764,537 		JBrowse link
G Wwox WW domain-containing oxidoreductase acts_upstream_of_or_within ISO (PMID:19366691) RGD PMID:19366691 NCBI chr19:42,432,141...43,360,278
Ensembl chr19:42,432,152...43,359,391 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    cellular process 18196
      signal transduction 7018
        signal transduction in absence of ligand 78
          extrinsic apoptotic signaling pathway in absence of ligand 76
            regulation of extrinsic apoptotic signaling pathway in absence of ligand 48
              negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 35
              positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 14
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13308
      regulation of biological process 12905
        signaling 7593
          signal transduction 7018
            cell surface receptor signaling pathway 2814
              extrinsic apoptotic signaling pathway 243
                extrinsic apoptotic signaling pathway in absence of ligand 76
                  regulation of extrinsic apoptotic signaling pathway in absence of ligand 48
                    negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 35
                    positive regulation of extrinsic apoptotic signaling pathway in absence of ligand 14
paths to the root