Gene: Agap2 (ArfGAP with GTPase domain, ankyrin repeat and PH domain 2) Rattus norvegicus
Symbol: Agap2
Name: ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
Description: ENCODES a protein that exhibits protein kinase activator activity; protein kinase binding; INVOLVED IN negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; negative regulation of neuron apoptotic process; positive regulation of phosphatidylinositol 3-kinase signaling; PARTICIPATES IN endocytosis pathway; FOUND IN nucleus; mitochondrion (ortholog); nucleolus (ortholog); INTERACTS WITH ammonium chloride; bisphenol A; cocaine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AGAP-2; arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2; centaurin, gamma 1; centaurin-gamma-1; Centg1; cnt-g1; nuclear GTPase PIKE; phosphatidylinositol 3-kinase enhancer; phosphatidylinositol-3-kinase enhancer; Pike
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0770,360,199 - 70,377,422 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0770,538,136 - 70,555,124 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4767,031,300 - 67,043,909 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1767,052,029 - 67,059,503 (+)NCBI
Celera760,045,054 - 60,057,649 (+)NCBICelera
Cytogenetic Map7q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Agap2
AGR Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 628844
Created: 2003-02-27
Species: Rattus norvegicus
Last Modified: 2017-11-07
Status: ACTIVE