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ONTOLOGY REPORT - ANNOTATIONS

Term:positive regulation of protein kinase activity
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Accession:GO:0045860 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein kinase activity.
Synonyms:exact_synonym: up regulation of protein kinase activity;   upregulation of protein kinase activity
 narrow_synonym: stimulation of protein kinase activity


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positive regulation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Axin1 axin 1 IDA RGD PMID:15228590 RGD:1304344 NCBI chr10:15,163,477...15,215,615
Ensembl chr10:15,163,684...15,215,615 		JBrowse link
G Axin2 axin 2 IDA RGD PMID:9566905 RGD:68736 NCBI chr10:93,893,830...93,927,042
Ensembl chr10:93,899,245...93,926,231 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:7642608 RGD:632489 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Ccnb1 cyclin B1 IMP histone H1 RGD PMID:15291744 RGD:1578405 NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172 		JBrowse link
G Dag1 dystroglycan 1 IMP RGD PMID:18556591 RGD:11541067 NCBI chr 8:108,890,926...108,955,611
Ensembl chr 8:108,890,929...108,952,325 		JBrowse link
G Daxx death-domain associated protein IMP RGD PMID:21572393 RGD:9587767 NCBI chr20:4,970,090...4,976,145
Ensembl chr20:4,970,092...4,975,843 		JBrowse link
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A IMP RGD PMID:9653190 RGD:8554053 NCBI chr 4:32,970,501...33,292,360
Ensembl chr 4:33,024,450...33,286,907 		JBrowse link
G Sdc4 syndecan 4 IMP RGD PMID:12571249 RGD:1580031 NCBI chr 3:153,154,888...153,173,576
Ensembl chr 3:153,154,896...153,173,580 		JBrowse link
activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Agtr1a angiotensin II receptor, type 1a IMP RGD PMID:9314843 RGD:6478796 NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946 		JBrowse link
G Ghr growth hormone receptor IDA RGD PMID:11244571 RGD:1624962 NCBI chr 2:52,541,452...52,804,960
Ensembl chr 2:52,542,594...52,804,735 		JBrowse link
G Prl3d4 prolactin family 3, subfamily D, member 4 IMP RGD PMID:8822264 RGD:1298822 NCBI chr17:37,325,804...37,332,641
Ensembl chr17:37,325,806...37,332,667 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:11818507 RGD:633057 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
activation of protein kinase A activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ucn urocortin IDA RGD PMID:19460778 RGD:5508168 NCBI chr 6:25,238,120...25,238,950
Ensembl chr 6:25,238,120...25,238,950 		JBrowse link
activation of protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adnp activity-dependent neuroprotector homeobox IDA Fyn kinase RGD PMID:19047645 RGD:2312772 NCBI chr 3:156,886,921...156,921,500
Ensembl chr 3:156,891,381...156,917,312 		JBrowse link
G Camkk1 calcium/calmodulin-dependent protein kinase kinase 1 IDA RGD PMID:16054095 RGD:2311420 NCBI chr10:57,637,335...57,660,498
Ensembl chr10:57,637,391...57,660,498 		JBrowse link
G Camkk2 calcium/calmodulin-dependent protein kinase kinase 2 IDA RGD PMID:16054095 RGD:2311420 NCBI chr12:33,791,023...33,845,000
Ensembl chr12:33,791,052...33,843,279 		JBrowse link
G Drd2 dopamine receptor D2 IDA RGD PMID:12086672 RGD:1580677 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Hnf1a HNF1 homeobox A IMP RGD PMID:20841353 RGD:150540305 NCBI chr12:41,638,536...41,672,806
Ensembl chr12:41,645,587...41,672,104 		JBrowse link
activation of protein kinase B activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prkcz protein kinase C, zeta IMP in hepatocytes RGD PMID:15007074 RGD:1642700 NCBI chr 5:165,817,786...165,930,386
Ensembl chr 5:165,819,466...165,930,367 		JBrowse link
negative regulation of activation of Janus kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hnf4a hepatocyte nuclear factor 4, alpha IDA RGD PMID:16584384 RGD:1625011 NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320 		JBrowse link
positive regulation of cAMP-dependent protein kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adcy10 adenylate cyclase 10 IMP RGD PMID:31172217 RGD:329403053 NCBI chr13:77,747,752...77,833,952
Ensembl chr13:77,768,468...77,833,951 		JBrowse link
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cdc6 cell division cycle 6 IMP RGD PMID:22223646 RGD:10045360 NCBI chr10:83,864,189...83,878,011
Ensembl chr10:83,864,638...83,878,011 		JBrowse link
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 IDA RGD PMID:10721722 RGD:632478 NCBI chr 3:142,838,081...142,872,669
Ensembl chr 3:142,708,028...142,872,677 		JBrowse link
G Cdkn1b cyclin-dependent kinase inhibitor 1B IMP RGD PMID:22223646 RGD:10045360 NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982 		JBrowse link
positive regulation of epidermal growth factor-activated receptor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adora1 adenosine A1 receptor IMP RGD PMID:19574994 RGD:2317913 NCBI chr13:45,658,872...45,695,821
Ensembl chr13:45,658,872...45,695,801 		JBrowse link
positive regulation of JUN kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il1b interleukin 1 beta IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il1rn interleukin 1 receptor antagonist IMP RGD PMID:12667655 RGD:1626684 NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445 		JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Map3k5 mitogen-activated protein kinase kinase kinase 5 IMP RGD PMID:20716917 RGD:10412640 NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800 		JBrowse link
G Ptk2b protein tyrosine kinase 2 beta IMP RGD PMID:15226266 RGD:1642623 NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
G Tiam1 TIAM Rac1 associated GEF 1 IMP RGD PMID:16203995 RGD:10043312 NCBI chr11:29,031,347...29,380,153
Ensembl chr11:29,031,348...29,159,901 		JBrowse link
positive regulation of MAP kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Csk C-terminal Src kinase IDA RGD PMID:10884975 RGD:5134370 NCBI chr 8:58,029,748...58,048,742
Ensembl chr 8:58,029,749...58,048,292 		JBrowse link
G Htr2a 5-hydroxytryptamine receptor 2A IMP RGD PMID:15087293 RGD:1624373 NCBI chr15:49,950,035...50,022,188
Ensembl chr15:49,950,804...50,020,928 		JBrowse link
G Ilk integrin-linked kinase IMP inhibits Gsk3b which in turn inhibits Erk/Mapk3 activation RGD PMID:17182785 RGD:2301767 NCBI chr 1:160,088,839...160,095,140
Ensembl chr 1:160,088,897...160,095,140 		JBrowse link
G Iqgap1 IQ motif containing GTPase activating protein 1 IMP RGD PMID:23987506 RGD:11049533 NCBI chr 1:134,679,581...134,769,776
Ensembl chr 1:134,679,586...134,769,755 		JBrowse link
G Kras KRAS proto-oncogene, GTPase IMP RGD PMID:10969813 RGD:1600497 NCBI chr 4:178,185,418...178,218,484 JBrowse link
G Map3k1 mitogen-activated protein kinase kinase kinase 1 IDA RGD PMID:9110999 RGD:2293488 NCBI chr 2:43,348,572...43,414,706
Ensembl chr 2:43,350,098...43,414,463 		JBrowse link
G Prkcd protein kinase C, delta IMP RGD PMID:16935468 RGD:1642549 NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352 		JBrowse link
G Src SRC proto-oncogene, non-receptor tyrosine kinase IMP RGD PMID:11941412 RGD:150523765 NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476 		JBrowse link
G Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 IMP RGD PMID:21607062 RGD:5508182 NCBI chr 7:111,675,829...111,707,058
Ensembl chr 7:111,686,371...111,707,058 		JBrowse link
positive regulation of protein kinase C activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Marcks myristoylated alanine rich protein kinase C substrate IDA RGD PMID:16341931 RGD:9685306 NCBI chr20:40,685,315...40,691,012
Ensembl chr20:40,685,315...40,691,012 		JBrowse link
G Ror2 receptor tyrosine kinase-like orphan receptor 2 IMP RGD PMID:25825749 RGD:11537351 NCBI chr17:11,972,830...12,148,152
Ensembl chr17:11,972,830...12,148,152 		JBrowse link
positive regulation of protein serine/threonine kinase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 IMP Akt1 RGD PMID:18443201 RGD:4108490 NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19694
    metabolic process 11456
      primary metabolic process 10016
        protein metabolic process 4606
          protein modification process 2016
            protein phosphorylation 795
              positive regulation of protein phosphorylation 495
                positive regulation of protein kinase activity 40
                  activation of protein kinase activity + 12
                  positive regulation of activation of Janus kinase activity 0
                  positive regulation of cyclin-dependent protein kinase activity + 3
                  positive regulation of protein histidine kinase activity 0
                  positive regulation of protein serine/threonine kinase activity + 21
                  positive regulation of protein tyrosine kinase activity + 1
                  positive regulation of tau-protein kinase activity 0
Path 2
Term Annotations click to browse term
  biological_process 19694
    biological regulation 13308
      regulation of biological process 12905
        regulation of metabolic process 6432
          regulation of cellular metabolic process 5821
            regulation of phosphorus metabolic process 906
              regulation of phosphate metabolic process 903
                regulation of phosphorylation 743
                  regulation of protein phosphorylation 710
                    positive regulation of protein phosphorylation 495
                      positive regulation of protein kinase activity 40
                        activation of protein kinase activity + 12
                        positive regulation of activation of Janus kinase activity 0
                        positive regulation of cyclin-dependent protein kinase activity + 3
                        positive regulation of protein histidine kinase activity 0
                        positive regulation of protein serine/threonine kinase activity + 21
                        positive regulation of protein tyrosine kinase activity + 1
                        positive regulation of tau-protein kinase activity 0
paths to the root