| (+)-pilocarpine | multiple interactions | EXP | | 6480464 | [2-chloro-N(6)cyclopentyladenosine binds to and results in increased activity of ADORA1 protein] which results in decreased susceptibility to Pilocarpine | CTD | PMID:11311893 |
| 1,4-dithiothreitol | multiple interactions | EXP | | 6480464 | [Dithiothreitol co-treated with Cadmium Chloride] inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]; more ... | CTD | PMID:10413299 |
| 1-naphthyl isothiocyanate | increases response to substance | ISO | RGD:730818 | 6480464 | ADORA1 protein results in increased susceptibility to 1-Naphthylisothiocyanate | CTD | PMID:22956627 |
| 17beta-estradiol | multiple interactions | ISO | RGD:730817 | 6480464 | Estradiol promotes the reaction [ESR1 protein binds to ADORA1 promoter] | CTD | PMID:19698761 |
| 17beta-estradiol | increases expression | ISO | RGD:730817 | 6480464 | Estradiol results in increased expression of ADORA1 mRNA | CTD | PMID:23019147 |
| 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ADORA1 protein | CTD | PMID:18950269 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:730818 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADORA1 mRNA | CTD | PMID:18172886 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:730818 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADORA1 mRNA | CTD | PMID:18172886 PMID:19770486 |
| 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:730818 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ADORA1 mRNA | CTD | PMID:19770486 PMID:18172886 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:730818 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of ADORA1 mRNA | CTD | PMID:19933214 |
| 3,4-methylenedioxymethamphetamine | increases expression | ISO | RGD:730818 | 6480464 | N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of ADORA1 mRNA | CTD | PMID:20188158 |
| 4-hydroxynon-2-enal | decreases expression | ISO | RGD:730817 | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of ADORA1 mRNA | CTD | PMID:12419474 |
| acetylsalicylic acid | affects response to substance | ISO | RGD:730817 | 6480464 | ADORA1 polymorphism affects the susceptibility to Aspirin | CTD | PMID:19019667 |
| adenosine | multiple interactions | ISO | RGD:730817 | 6480464 | Adenosine analog binds to and affects the activity of ADORA1 protein; more ... | CTD | PMID:20571079 |
| adenosine | multiple interactions | EXP | | 6480464 | [lead acetate results in increased expression of ADORA1 protein] which results in increased abundance of Adenosine | CTD | PMID:20932874 |
| adenosine | multiple interactions | EXP | | 6480464 | Adenosine analog binds to and results in increased activity of ADORA1 protein | CTD | PMID:11520205 PMID:10649980 |
| adenosine | multiple interactions | EXP | | 6480464 | Adenosine analog binds to and results in increased activity of ADORA1 protein | CTD | PMID:10649980 PMID:11520205 |
| adenosine | multiple interactions | ISO | RGD:730817 | 6480464 | Adenosine analog binds to and results in decreased activity of ADORA1 protein | CTD | PMID:18404447 |
| adenosine | affects binding | ISO | RGD:730817 | 6480464 | Adenosine binds to ADORA1 protein | CTD | PMID:18404447 |
| adenosine 5'-methylenediphosphate | multiple interactions | EXP | | 6480464 | adenosine 5'-methylenediphosphate inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]; more ... | CTD | PMID:19966059 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ADORA1 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | decreases expression | ISO | RGD:730818 | 6480464 | Benzo(a)pyrene results in decreased expression of ADORA1 mRNA | CTD | PMID:19770486 |
| benzo[a]pyrene | increases expression | ISO | RGD:730818 | 6480464 | Benzo(a)pyrene results in increased expression of ADORA1 mRNA | CTD | PMID:22228805 |
| benzo[a]pyrene | multiple interactions | ISO | RGD:730818 | 6480464 | AHR protein affects the reaction [Benzo(a)pyrene affects the expression of ADORA1 mRNA] | CTD | PMID:22228805 |
| bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:730818 | 6480464 | Mustard Gas results in increased expression of ADORA1 mRNA | CTD | PMID:15674843 |
| C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of ADORA1 mRNA | CTD | PMID:19167457 |
| cadmium dichloride | multiple interactions | EXP | | 6480464 | Cadmium Chloride promotes the reaction [Dithionitrobenzoic Acid inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]]; more ... | CTD | PMID:10413299 |
| caffeine | decreases activity | EXP | | 6480464 | Caffeine results in decreased activity of ADORA1 protein | CTD | PMID:15708489 |
| caffeine | decreases activity | ISO | RGD:730818 | 6480464 | Caffeine results in decreased activity of ADORA1 protein | CTD | PMID:22164264 |
| caffeine | multiple interactions | EXP | | 6480464 | Caffeine promotes the reaction [Phenylisopropyladenosine binds to and results in increased activity of ADORA1 protein] | CTD | PMID:3003150 |
| caffeine | multiple interactions | EXP | | 6480464 | Caffeine inhibits the reaction [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein] | CTD | PMID:10401785 |
| caffeine | increases expression | ISO | RGD:730818 | 6480464 | Caffeine results in increased expression of ADORA1 protein | CTD | PMID:7996441 |
| caffeine | multiple interactions | ISO | RGD:730818 | 6480464 | [8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine] | CTD | PMID:7996441 |
| caffeine | decreases expression | EXP | | 6480464 | Caffeine results in decreased expression of ADORA1 mRNA | CTD | PMID:12153486 |
| calcitriol | multiple interactions | ISO | RGD:730817 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of ADORA1 mRNA | CTD | PMID:21592394 |
| calcitriol | decreases expression | ISO | RGD:730817 | 6480464 | Calcitriol results in decreased expression of ADORA1 mRNA | CTD | PMID:21592394 |
| carbonyl sulfide | increases expression | EXP | | 6480464 | carbonyl sulfide results in increased expression of ADORA1 mRNA | CTD | PMID:19395590 |
| clofibrate | multiple interactions | ISO | RGD:730818 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ADORA1 mRNA; more ... | CTD | PMID:17585979 |
| clonidine | multiple interactions | EXP | | 6480464 | [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (amino form) | multiple interactions | EXP | | 6480464 | [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| clonidine (imino form) | multiple interactions | EXP | | 6480464 | [1,3-dipropyl-8-(2-amino-4-chlorophenyl)xanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to Clonidine | CTD | PMID:8987795 |
| cobalt dichloride | multiple interactions | ISO | RGD:730818 | 6480464 | [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in increased susceptibility to cobaltous chloride | CTD | PMID:18727925 |
| cobalt dichloride | decreases response to substance | ISO | RGD:730818 | 6480464 | ADORA1 protein results in decreased susceptibility to cobaltous chloride | CTD | PMID:18727925 |
| cocaine | affects expression | EXP | | 6480464 | Cocaine affects the expression of ADORA1 mRNA; more ... | CTD | PMID:12358776 |
| cocaine | affects response to substance | ISO | RGD:730818 | 6480464 | ADORA1 affects the susceptibility to Cocaine | CTD | PMID:19092996 |
| cytidine | increases activity | EXP | | 6480464 | Cytidine results in increased activity of ADORA1 protein | CTD | PMID:18313046 |
| dibutyl phthalate | decreases expression | ISO | RGD:730818 | 6480464 | Dibutyl Phthalate results in decreased expression of ADORA1 mRNA | CTD | PMID:21266533 |
| dibutyl phthalate | decreases expression | ISO | RGD:730818 | 6480464 | Dibutyl Phthalate results in decreased expression of ADORA1 mRNA | CTD | PMID:17361019 PMID:21266533 |
| dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of ADORA1 mRNA | CTD | PMID:15620428 |
| diethyl pyrocarbonate | multiple interactions | EXP | | 6480464 | Diethyl Pyrocarbonate inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein] | CTD | PMID:10413299 |
| diethylstilbestrol | increases expression | ISO | RGD:730817 | 6480464 | Diethylstilbestrol results in increased expression of ADORA1 mRNA | CTD | PMID:15766595 |
| dopamine | multiple interactions | EXP | | 6480464 | [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine] | CTD | PMID:11043458 |
| DPCPX | multiple interactions | EXP | | 6480464 | [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in decreased susceptibility to 2-chloro-N(6)cyclopentyladenosine | CTD | PMID:11311893 |
| DPCPX | multiple interactions | EXP | | 6480464 | 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]]; more ... | CTD | PMID:19966059 |
| DPCPX | multiple interactions | ISO | RGD:730818 | 6480464 | 1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein | CTD | PMID:18727925 PMID:22164264 |
| DPCPX | multiple interactions | ISO | RGD:730818 | 6480464 | [1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein] which results in increased susceptibility to cobaltous chloride | CTD | PMID:18727925 |
| DPCPX | multiple interactions | EXP | | 6480464 | 1,3-dipropyl-8-cyclopentylxanthine binds to and results in decreased activity of ADORA1 protein | CTD | PMID:10642308 more ... |
| gefitinib | decreases expression | ISO | RGD:730817 | 6480464 | gefitinib results in decreased expression of ADORA1 mRNA | CTD | PMID:16685379 |
| hydrogen peroxide | decreases expression | ISO | RGD:730817 | 6480464 | Hydrogen Peroxide results in decreased expression of ADORA1 mRNA | CTD | PMID:12419474 |
| indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of ADORA1 mRNA | CTD | PMID:21396975 |
| L-cysteine | multiple interactions | EXP | | 6480464 | Cysteine inhibits the reaction [Cadmium Chloride inhibits the reaction [2-chloro-N(6)cyclopentyladenosine binds to ADORA1 protein]] | CTD | PMID:10413299 |
| lead diacetate | increases expression | EXP | | 6480464 | lead acetate results in increased expression of ADORA1 protein | CTD | PMID:20932874 |
| lead diacetate | multiple interactions | EXP | | 6480464 | [lead acetate results in increased expression of ADORA1 protein] which results in increased abundance of Adenosine | CTD | PMID:20932874 |
| lead(0) | decreases expression | ISO | RGD:730817 | 6480464 | Lead results in decreased expression of ADORA1 mRNA | CTD | PMID:19921347 |
| maneb | multiple interactions | ISO | RGD:730818 | 6480464 | [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA | CTD | PMID:23017109 |
| methamphetamine | multiple interactions | ISO | RGD:730818 | 6480464 | [8-cyclopentyl-1,3-dimethylxanthine binds to and results in decreased activity of ADORA1 protein] inhibits the reaction [[Caffeine co-treated with [N(6)-cyclopentyladenosine binds to and results in increased activity of ADORA1 protein]] results in decreased susceptibility to Methamphetamine] | CTD | PMID:7996441 |
| methamphetamine | multiple interactions | EXP | | 6480464 | [N(6)-cyclohexyladenosine binds to and results in increased activity of ADORA1 protein] promotes the reaction [Methamphetamine results in increased secretion of Dopamine]; more ... | CTD | PMID:11043458 |
| mono(2-ethylhexyl) phthalate | decreases expression | ISO | RGD:730818 | 6480464 | mono-(2-ethylhexyl)phthalate results in decreased expression of ADORA1 mRNA | CTD | PMID:22401849 |
| morphine | affects response to substance | ISO | RGD:730818 | 6480464 | ADORA1 protein affects the susceptibility to Morphine | CTD | PMID:9407998 |
| paracetamol | multiple interactions | ISO | RGD:730818 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of ADORA1 mRNA; more ... | CTD | PMID:17585979 |
| paraquat | multiple interactions | ISO | RGD:730818 | 6480464 | [SNCA protein co-treated with Maneb co-treated with Paraquat] results in decreased expression of ADORA1 mRNA | CTD | PMID:23017109 |
| perfluorooctane-1-sulfonic acid | affects expression | ISO | RGD:730818 | 6480464 | perfluorooctane sulfonic acid affects the expression of ADORA1 mRNA | CTD | PMID:19429403 |
| perfluorooctane-1-sulfonic acid | decreases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in decreased expression of ADORA1 mRNA | CTD | PMID:20136073 |
| perfluorooctanoic acid | affects expression | ISO | RGD:730818 | 6480464 | perfluorooctanoic acid affects the expression of ADORA1 mRNA | CTD | PMID:19429403 |
| phenylephrine | multiple interactions | EXP | | 6480464 | 1,3-dipropyl-8-cyclopentylxanthine inhibits the reaction [N(6)-cyclopentyladenosine inhibits the reaction [Phenylephrine results in increased expression of ADORA1 mRNA]]; more ... | CTD | PMID:19966059 |
| phenylephrine | increases expression | EXP | | 6480464 | Phenylephrine results in increased expression of ADORA1 mRNA; more ... | CTD | PMID:19966059 |
| prazosin | multiple interactions | EXP | | 6480464 | Prazosin inhibits the reaction [Phenylephrine results in increased expression of ADORA1 protein] | CTD | PMID:19966059 |
| resveratrol | multiple interactions | EXP | | 6480464 | [8-cyclopentyl-1,3-dimethylxanthine results in decreased activity of ADORA1 protein] which results in decreased susceptibility to resveratrol; more ... | CTD | PMID:15345477 |
| tamoxifen | affects expression | ISO | RGD:730818 | 6480464 | Tamoxifen affects the expression of ADORA1 mRNA | CTD | PMID:20937368 |
| tert-butyl hydroperoxide | decreases expression | ISO | RGD:730817 | 6480464 | tert-Butylhydroperoxide results in decreased expression of ADORA1 mRNA | CTD | PMID:12419474 |
| testosterone | multiple interactions | ISO | RGD:730817 | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of ADORA1 mRNA | CTD | PMID:21592394 |
| testosterone | decreases expression | ISO | RGD:730817 | 6480464 | Testosterone results in decreased expression of ADORA1 mRNA | CTD | PMID:21592394 |
| tetrachloromethane | increases expression | ISO | RGD:730818 | 6480464 | Carbon Tetrachloride results in increased expression of ADORA1 mRNA | CTD | PMID:18263696 |
| tetrachloromethane | affects expression | EXP | | 6480464 | Carbon Tetrachloride affects the expression of ADORA1 mRNA | CTD | PMID:12734012 |
| tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ADORA1 protein | CTD | PMID:12629582 |
| theophylline | multiple interactions | EXP | | 6480464 | Theophylline binds to and results in decreased activity of ADORA1 protein | CTD | PMID:9535120 |
| theophylline | multiple interactions | EXP | | 6480464 | Theophylline binds to and results in decreased activity of ADORA1 protein | CTD | PMID:9535120 PMID:14992338 |
| theophylline | decreases expression | EXP | | 6480464 | Theophylline results in decreased expression of ADORA1 mRNA | CTD | PMID:12153486 |
| theophylline | multiple interactions | EXP | | 6480464 | Theophylline binds to and results in decreased activity of ADORA1 protein | CTD | PMID:14992338 PMID:9535120 |
| theophylline | decreases activity | EXP | | 6480464 | Theophylline results in decreased activity of ADORA1 protein | CTD | PMID:15708489 |
| titanium dioxide | increases expression | ISO | RGD:730818 | 6480464 | titanium dioxide results in increased expression of ADORA1 mRNA | CTD | PMID:21259345 |
| trans-resveratrol | multiple interactions | EXP | | 6480464 | [8-cyclopentyl-1,3-dimethylxanthine results in decreased activity of ADORA1 protein] which results in decreased susceptibility to resveratrol; more ... | CTD | PMID:15345477 |
| uridine | increases activity | EXP | | 6480464 | Uridine results in increased activity of ADORA1 protein | CTD | PMID:18313046 |
| zinc dichloride | multiple interactions | EXP | | 6480464 | zinc chloride inhibits the reaction [N(6)-cyclohexyladenosine binds to ADORA1 protein] | CTD | PMID:10413299 |