ONTOLOGY REPORT - ANNOTATIONS
Term: negative regulation of ubiquitin-dependent protein catabolic process
Accession: GO:2000059
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Definition: Any process that stops, prevents, or reduces the frequency, rate or extent of ubiquitin-dependent protein catabolic process.
Synonyms: narrow_synonym: negative regulation of protein ubiquitination during ubiquitin-dependent protein breakdown; negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolism; negative regulation of protein ubiquitination during ubiquitin-dependent protein degradation; negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitinylation during ubiquitin-dependent protein catabolism; negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolic process; negative regulation of protein ubiquitylation during ubiquitin-dependent protein catabolism
related_synonym: negative regulation of protein degradation tagging activity; negative regulation of protein ubiquitination during ubiquitin-dependent protein catabolic process
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Anks1a
ankyrin repeat and sterile alpha motif domain containing 1A
acts_upstream_of_or_within
ISO
(PMID:20100865)
RGD
PMID:20100865
NCBI chr20:5,963,658...6,117,139
Ensembl chr20:5,963,678...6,117,148
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Cdkn2a
cyclin-dependent kinase inhibitor 2A
involved_in acts_upstream_of_or_within
ISO
(PMID:16173922) (PMID:18560357) (PMID:23277542)
RGD
PMID:16173922 PMID:18560357 PMID:23277542
NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149
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Hfe
homeostatic iron regulator
involved_in
ISO
(PMID:24904118)
RGD
PMID:24904118
NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
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Hipk2
homeodomain interacting protein kinase 2
involved_in
ISO
(PMID:21628596)
RGD
PMID:21628596
NCBI chr 4:67,439,327...67,619,223
Ensembl chr 4:67,440,501...67,619,223
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Pdcl3
phosducin-like 3
acts_upstream_of_or_within involved_in
ISO IEA
(PMID:23792958) GO_REF:0000107
RGD Ensembl
PMID:23792958
GO_REF:0000107
NCBI chr 9:41,234,322...41,243,769
Ensembl chr 9:41,234,234...41,243,735
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Pml
PML nuclear body scaffold
involved_in
ISO
(PMID:15195100)
RGD
PMID:15195100
NCBI chr 8:58,627,347...58,661,927
Ensembl chr 8:58,628,837...58,658,971
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Prmt6
protein arginine methyltransferase 6
involved_in
ISO
(MGI:5688415|PMID:26070566)
RGD
PMID:26070566
MGI:5688415
NCBI chr 2:197,927,750...197,932,760
Ensembl chr 2:197,927,220...197,933,648
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Psen1
presenilin 1
involved_in
ISO
(MGI:4887523|PMID:20208556)
RGD
PMID:20208556
MGI:4887523
NCBI chr 6:103,323,052...103,375,088
Ensembl chr 6:103,323,120...103,371,650
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Psen2
presenilin 2
involved_in
ISO
(MGI:4887523|PMID:20208556)
RGD
PMID:20208556
MGI:4887523
NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
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Qrich2
glutamine rich 2
involved_in
ISO
(PMID:30683861) (MGI:6277293|PMID:30683861)
RGD
PMID:30683861
MGI:6277293
NCBI chr10:101,669,240...101,697,643
Ensembl chr10:101,669,224...101,697,656
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Rpl11
ribosomal protein L11
involved_in
ISO
(PMID:18560357)
RGD
PMID:18560357
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
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Rpl23
ribosomal protein L23
involved_in
ISO IEA
(PMID:15314173) GO_REF:0000107
RGD Ensembl
PMID:15314173
GO_REF:0000107
NCBI chr10:82,771,878...82,775,840
Ensembl chr10:82,771,538...82,775,870
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Rpl5
ribosomal protein L5
involved_in
ISO
(PMID:18560357)
RGD
PMID:18560357
NCBI chr14:1,843,856...1,850,301
Ensembl chr14:1,843,770...1,850,290
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Rps7
ribosomal protein S7
involved_in
ISO
(PMID:17310983)
RGD
PMID:17310983
NCBI chr 6:45,266,200...45,271,064
Ensembl chr 6:45,223,980...45,271,145
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Sgta
small glutamine rich tetratricopeptide repeat co-chaperone alpha
involved_in
ISS ISO IEA
GO_REF:0000024 (PMID:23129660) GO_REF:0000107
UniProt RGD Ensembl
PMID:23129660
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:8,653,681...8,670,460
Ensembl chr 7:8,653,778...8,670,458
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Sufu
SUFU negative regulator of hedgehog signaling
acts_upstream_of_or_within
ISO
MGI:1343085 (PMID:19684112)
RGD
PMID:19684112
NCBI chr 1:245,257,725...245,355,576
Ensembl chr 1:245,257,768...245,355,577
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Svip
small VCP interacting protein
involved_in
IDA
PMID:17000876
ParkinsonsUK-UCL
PMID:17000876
RGD:10047192
NCBI chr 1:101,587,128...101,592,818
Ensembl chr 1:101,587,128...101,593,116
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Taf1
TATA-box binding protein associated factor 1
involved_in
ISO
(PMID:17237821)
RGD
PMID:17237821
NCBI chr X:66,640,915...66,716,543
Ensembl chr X:66,640,982...66,716,543
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Trim39
tripartite motif-containing 39
involved_in
ISO
(PMID:19100260)
RGD
PMID:19100260
NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
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Usp14
ubiquitin specific peptidase 14
involved_in
ISO
(PMID:19135427)
RGD
PMID:19135427
NCBI chr18:1,018,111...1,057,727
Ensembl chr18:1,019,400...1,057,519
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Usp5
ubiquitin specific peptidase 5
involved_in
ISO
(PMID:24424410)
RGD
PMID:24424410
NCBI chr 4:157,619,663...157,634,681
Ensembl chr 4:157,619,643...157,634,711
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Wnt1
Wnt family member 1
acts_upstream_of_or_within
ISO
(PMID:16601693)
RGD
PMID:16601693
NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651
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Bag5
BAG cochaperone 5
involved_in
ISO
(PMID:24475098)
RGD
PMID:24475098
NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
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Bag6
BAG cochaperone 6
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (MGI:3808636|PMID:18678708)
UniProt Ensembl RGD
PMID:18678708
GO_REF:0000024 GO_REF:0000107 MGI:3808636
NCBI chr20:3,675,938...3,690,414
Ensembl chr20:3,675,938...3,688,657
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Camlg
calcium modulating ligand
involved_in
ISO
UniProtKB:Q9H9V4 (PMID:20553626)
RGD
PMID:20553626
NCBI chr17:8,992,697...9,003,576
Ensembl chr17:8,992,696...9,003,552
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Ccar2
cell cycle and apoptosis regulator 2
involved_in
ISO
(PMID:23398316)
RGD
PMID:23398316
NCBI chr15:45,212,797...45,228,001
Ensembl chr15:45,212,803...45,227,636
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Clec16a
C-type lectin domain containing 16A
acts_upstream_of_or_within
ISO
MGI:5648633 (PMID:24949970)
RGD
PMID:24949970
NCBI chr10:4,927,799...5,123,749
Ensembl chr10:4,928,030...5,123,578
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Csnk2a1
casein kinase 2 alpha 1
involved_in
ISO
UniProtKB:P19784|UniProtKB:P25686|UniProtKB:P67870 (PMID:28031292)
RGD
PMID:28031292
NCBI chr 3:140,709,984...140,756,757
Ensembl chr 3:140,709,991...140,756,696
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Csnk2a2
casein kinase 2 alpha 2
involved_in
ISO
UniProtKB:P25686|UniProtKB:P67870|UniProtKB:P68400 (PMID:28031292)
RGD
PMID:28031292
NCBI chr19:9,556,443...9,596,080
Ensembl chr19:9,556,260...9,596,080
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Csnk2b
casein kinase 2 beta
involved_in
ISO
(PMID:28031292)
RGD
PMID:28031292
NCBI chr20:3,700,363...3,705,331
Ensembl chr20:3,698,733...3,707,133
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Ddrgk1
DDRGK domain containing 1
involved_in
ISO
(PMID:28263186)
RGD
PMID:28263186
NCBI chr 3:117,861,916...117,882,680
Ensembl chr 3:117,861,653...117,882,680
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Eif3h
eukaryotic translation initiation factor 3, subunit H
involved_in
ISO IEA
(PMID:32269044) GO_REF:0000107
RGD Ensembl
PMID:32269044
GO_REF:0000107
NCBI chr 7:83,091,037...83,174,451
Ensembl chr 7:83,091,039...83,174,451
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Fhit
fragile histidine triad diadenosine triphosphatase
involved_in
ISO IBA IEA ISS
(PMID:15313915) GO_REF:0000033 GO_REF:0000107 GO_REF:0000024
RGD GO_Central Ensembl UniProt
PMID:15313915
GO_REF:0000024 GO_REF:0000033 GO_REF:0000107
NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340
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Gipc1
GIPC PDZ domain containing family, member 1
involved_in
ISO IEA
(MGI:3807767|PMID:11546783) GO_REF:0000107
RGD Ensembl
PMID:11546783
GO_REF:0000107 MGI:3807767
NCBI chr19:24,474,291...24,487,083
Ensembl chr19:24,453,123...24,486,997
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Hfe
homeostatic iron regulator
involved_in
ISO
(PMID:24904118) GO:0010628 (MGI:5603002|PMID:24904118)
RGD
PMID:24904118
MGI:5603002
NCBI chr17:41,413,451...41,421,502
Ensembl chr17:41,413,451...41,421,502
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Hsp90ab1
heat shock protein 90 alpha family class B member 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:24613385)
UniProt Ensembl RGD
PMID:24613385
GO_REF:0000024 GO_REF:0000107
NCBI chr 9:15,432,986...15,438,358
Ensembl chr 9:15,433,691...15,438,488
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Klhl40
kelch-like family member 40
involved_in acts_upstream_of_or_within
IBA ISO
GO_REF:0000033 (PMID:24960163)
GO_Central RGD
PMID:24960163
GO_REF:0000033
NCBI chr 8:121,441,285...121,446,801
Ensembl chr 8:121,441,287...121,446,800
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Map1a
microtubule-associated protein 1A
involved_in
ISO
(MGI:5703671|PMID:26609151)
RGD
PMID:26609151
MGI:5703671
NCBI chr 3:108,263,217...108,283,936
Ensembl chr 3:108,263,151...108,282,899
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Mtm1
myotubularin 1
acts_upstream_of_or_within
ISO
MGI:2450997 (PMID:23695157)
RGD
PMID:23695157
NCBI chr 6:488,923...506,882
Ensembl chr 6:488,969...506,860
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N4bp1
Nedd4 binding protein 1
involved_in
ISO IBA
(MGI:3829128|PMID:17592138) GO_REF:0000033
RGD GO_Central
PMID:17592138
GO_REF:0000033 MGI:3829128
NCBI chr19:20,222,811...20,273,570
Ensembl chr19:20,222,776...20,273,570
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Nop53
NOP53 ribosome biogenesis factor
involved_in
ISO
(PMID:22522597)
RGD
PMID:22522597
NCBI chr 1:76,629,084...76,636,902
Ensembl chr 1:76,629,069...76,636,902
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Ogt
O-linked N-acetylglucosamine (GlcNAc) transferase
involved_in
IEA ISO
GO_REF:0000107 (PMID:26678539)
Ensembl RGD
PMID:26678539
GO_REF:0000107
NCBI chr X:66,771,278...66,816,148
Ensembl chr X:66,771,349...66,816,146
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Park7
Parkinsonism associated deglycase
involved_in
ISO IEA
(PMID:17015834) GO_REF:0000107
RGD Ensembl
PMID:17015834
GO_REF:0000107
NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
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Pbk
PDZ binding kinase
acts_upstream_of_or_within
ISO
MGI:5293435 (PMID:21715333)
RGD
PMID:21715333
NCBI chr15:40,022,873...40,034,014
Ensembl chr15:40,023,002...40,034,014
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Phf20l1
PHD finger protein 20-like 1
involved_in
ISS IEA ISO
GO_REF:0000024 GO_REF:0000107 (PMID:24492612)
UniProt Ensembl RGD
PMID:24492612
GO_REF:0000024 GO_REF:0000107
NCBI chr 7:98,330,580...98,396,526
Ensembl chr 7:98,330,580...98,396,526
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Rpl11
ribosomal protein L11
involved_in
ISS ISO
GO_REF:0000024 (MGI:5897550|PMID:21804542)
UniProt RGD
PMID:21804542
GO_REF:0000024 MGI:5897550
NCBI chr 5:148,274,060...148,277,708
Ensembl chr 5:148,274,069...148,277,599
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Rpp21
ribonuclease P/MRP subunit p21
involved_in
IEA
GO_REF:0000107
Ensembl
GO_REF:0000107
NCBI chr20:2,018,170...2,020,100
Ensembl chr20:2,018,147...2,020,106
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Rybp
RING1 and YY1 binding protein
involved_in
ISO
(PMID:27060496)
RGD
PMID:27060496
NCBI chr 4:132,876,260...132,928,328
Ensembl chr 4:132,876,361...132,928,316
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Senp1
SUMO specific peptidase 1
acts_upstream_of_or_within
ISO
MGI:3818522 (PMID:17981124)
RGD
PMID:17981124
NCBI chr 7:129,163,173...129,226,766
Ensembl chr 7:129,165,774...129,221,598
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Shh
sonic hedgehog signaling molecule
involved_in acts_upstream_of_or_within
IEA ISO
GO_REF:0000107 (PMID:16611981)
Ensembl RGD
PMID:16611981
GO_REF:0000107
NCBI chr 4:6,954,017...6,963,170
Ensembl chr 4:6,954,017...6,963,170
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Smarcc1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
acts_upstream_of_or_within
ISO
(PMID:22285184)
RGD
PMID:22285184
NCBI chr 8:110,111,097...110,214,734
Ensembl chr 8:110,111,122...110,214,720
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Taf9
TATA-box binding protein associated factor 9
involved_in
ISO IEA
(PMID:11278372) GO_REF:0000107
RGD Ensembl
PMID:11278372
GO_REF:0000107
NCBI chr 2:31,794,316...31,798,324
Ensembl chr 2:31,794,142...31,798,769
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Tlk2
tousled-like kinase 2
involved_in
ISO
(PMID:20016786)
RGD
PMID:20016786
NCBI chr10:90,154,449...90,248,562
Ensembl chr10:90,156,813...90,248,561
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Trim39
tripartite motif-containing 39
involved_in
ISO IBA ISS
(PMID:23213251) GO_REF:0000033 GO_REF:0000024
RGD GO_Central UniProt
PMID:23213251
GO_REF:0000024 GO_REF:0000033
NCBI chr20:2,003,320...2,017,175
Ensembl chr20:1,983,533...2,020,117
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Ttc36
tetratricopeptide repeat domain 36
acts_upstream_of_or_within
ISO
MGI:5588394 (PMID:31537781)
RGD
PMID:31537781
NCBI chr 8:45,112,737...45,116,345
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Ubxn1
UBX domain protein 1
involved_in
ISS IBA ISO
GO_REF:0000024 GO_REF:0000033 (PMID:20351172)
UniProt GO_Central RGD
PMID:20351172
GO_REF:0000024 GO_REF:0000033
NCBI chr 1:205,765,309...205,769,234
Ensembl chr 1:205,745,120...205,816,520
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Uchl5
ubiquitin C-terminal hydrolase L5
involved_in
ISO
(PMID:23770237)
RGD
PMID:23770237
NCBI chr13:55,520,722...55,556,503
Ensembl chr13:55,520,729...55,556,502
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Usp26
ubiquitin specific peptidase 26
involved_in
ISO
(PMID:28839133) (MGI:5926846|PMID:28839133)
RGD
PMID:28839133
MGI:5926846
NCBI chr X:131,317,200...131,363,964
Ensembl chr X:131,319,194...131,363,970
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Usp38
ubiquitin specific peptidase 38
involved_in
ISO
(PMID:34102342)
RGD
PMID:34102342
NCBI chr19:27,006,046...27,037,449
Ensembl chr19:27,006,046...27,037,437
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Usp7
ubiquitin specific peptidase 7
involved_in
ISO IEA
(PMID:26678539) GO_REF:0000107
RGD Ensembl
PMID:26678539
GO_REF:0000107
NCBI chr10:6,880,684...6,925,355
Ensembl chr10:6,828,795...6,925,355
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Usp9x
ubiquitin specific peptidase 9, X-linked
involved_in
ISO
(PMID:33378666)
RGD
PMID:33378666
NCBI chr X:9,588,825...9,726,993
Ensembl chr X:9,588,825...9,696,711
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Wac
WW domain containing adaptor with coiled-coil
involved_in
ISO
(PMID:22354037)
RGD
PMID:22354037
NCBI chr17:55,922,686...55,984,286
Ensembl chr17:55,923,123...55,982,301
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Pabpn1l
PABPN1 like
acts_upstream_of_or_within
ISO
(PMID:32558204)
RGD
PMID:32558204
NCBI chr19:50,669,965...50,673,409
Ensembl chr19:50,669,967...50,673,366
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Styx
serine/threonine/tyrosine interacting protein
involved_in
ISO IBA
(PMID:28007894) GO_REF:0000033
RGD GO_Central
PMID:28007894
GO_REF:0000033
NCBI chr15:18,565,214...18,595,797
Ensembl chr15:18,564,633...18,593,524
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