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ONTOLOGY REPORT - ANNOTATIONS

Term:protein autoubiquitination
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Accession:GO:0051865 term browser browse the term
Definition:The ubiquitination by a protein of one or more of its own amino acid residues, or residues on an identical protein. Ubiquitination occurs on the lysine residue by formation of an isopeptide crosslink.
Synonyms:exact_synonym: protein auto-ubiquitination;   protein auto-ubiquitinylation;   protein autoubiquitinylation;   protein self-ubiquitination;   protein self-ubiquitinylation


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protein autoubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Amfr autocrine motility factor receptor involved_in ISO (PMID:24810856) RGD PMID:24810856 NCBI chr19:10,996,705...11,032,260
Ensembl chr19:10,996,099...11,032,247 		JBrowse link
G Asb4 ankyrin repeat and SOCS box-containing 4 involved_in ISO (MGI:3723573|PMID:17636018) RGD PMID:17636018 MGI:3723573 NCBI chr 4:33,506,992...33,544,630
Ensembl chr 4:33,506,992...33,544,630 		JBrowse link
G Bfar bifunctional apoptosis regulator involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr10:1,552,019...1,585,040
Ensembl chr10:1,552,072...1,585,038 		JBrowse link
G Brca1 BRCA1, DNA repair associated involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12890688), (PMID:20351172)
GO_REF:0000104		 UniProt
RGD		 PMID:12890688 PMID:20351172 GO_REF:0000024 GO_REF:0000104 NCBI chr10:86,417,441...86,477,762
Ensembl chr10:86,418,000...86,477,304 		JBrowse link
G Cbl Cbl proto-oncogene IDA RGD PMID:22203672 RGD:11576305 NCBI chr 8:44,487,824...44,571,620
Ensembl chr 8:44,489,410...44,571,176 		JBrowse link
G Cnot4 CCR4-NOT transcription complex, subunit 4 involved_in ISO (PMID:15001359) RGD PMID:15001359 NCBI chr 4:63,712,770...63,814,355
Ensembl chr 4:63,712,770...63,814,360 		JBrowse link
G Cul3 cullin 3 involved_in ISO
IEA		 (PMID:14528312)
GO_REF:0000107		 RGD
Ensembl		 PMID:14528312 GO_REF:0000107 NCBI chr 9:81,592,641...81,670,428
Ensembl chr 9:81,592,641...81,670,462 		JBrowse link
G Ddb2 damage specific DNA binding protein 2 involved_in ISO (PMID:12732143) RGD PMID:12732143 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631 		JBrowse link
G Dtx3l deltex E3 ubiquitin ligase 3L involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr11:64,814,926...64,824,539
Ensembl chr11:64,814,926...64,824,538 		JBrowse link
G Ercc8 ERCC excision repair 8, CSA ubiquitin ligase complex subunit involved_in ISO (PMID:12732143) RGD PMID:12732143 NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859 		JBrowse link
G Hectd1 HECT domain E3 ubiquitin protein ligase 1 acts_upstream_of_or_within ISO (PMID:22431752) RGD PMID:22431752 NCBI chr 6:69,181,429...69,268,045
Ensembl chr 6:69,181,436...69,268,053 		JBrowse link
G Itch itchy E3 ubiquitin protein ligase involved_in ISO (PMID:24790097) RGD PMID:24790097 NCBI chr 3:143,642,348...143,733,745
Ensembl chr 3:143,645,637...143,733,543 		JBrowse link
G Jade2 jade family PHD finger 2 acts_upstream_of_or_within ISO (PMID:25018020) RGD PMID:25018020 NCBI chr10:36,075,239...36,124,210
Ensembl chr10:36,078,917...36,116,984 		JBrowse link
G Klhl24 kelch-like family member 24 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:27798626)		 UniProt
Ensembl
RGD		 PMID:27798626 GO_REF:0000024 GO_REF:0000107 NCBI chr11:80,843,621...80,877,649
Ensembl chr11:80,846,755...80,877,636 		JBrowse link
G Lrsam1 leucine rich repeat and sterile alpha motif containing 1 involved_in ISO (PMID:15256501), (PMID:23245322) RGD PMID:15256501 PMID:23245322 NCBI chr 3:16,223,367...16,264,261
Ensembl chr 3:16,223,367...16,264,154 		JBrowse link
G Ltn1 listerin E3 ubiquitin protein ligase 1 involved_in ISO (MGI:3837634|PMID:19196968) RGD PMID:19196968 MGI:3837634 NCBI chr11:26,603,903...26,660,871
Ensembl chr11:26,603,903...26,660,886 		JBrowse link
G Marchf5 membrane associated ring-CH-type finger 5 involved_in ISO (PMID:16874301) RGD PMID:16874301 NCBI chr 1:234,931,137...234,953,849
Ensembl chr 1:234,931,271...234,952,632 		JBrowse link
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
IBA
IEA
ISO		 GO_REF:0000024
GO_REF:0000033
GO_REF:0000107
(MGI:6162398|PMID:18410486)		 UniProt
GO_Central
Ensembl
RGD		 PMID:18410486 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 MGI:6162398 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Mdm2 MDM2 proto-oncogene involved_in ISO (PMID:16479015), (PMID:17237821), (PMID:30879903) RGD PMID:16479015 PMID:17237821 PMID:30879903 NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915 		JBrowse link
G Nfx1 nuclear transcription factor, X-box binding 1 involved_in ISO (PMID:10500182) RGD PMID:10500182 NCBI chr 5:56,104,945...56,162,912
Ensembl chr 5:56,105,234...56,162,912 		JBrowse link
G Obi1 ORC ubiquitin ligase 1 involved_in ISO (PMID:31160578) RGD PMID:31160578 NCBI chr15:81,269,413...81,308,734
Ensembl chr15:81,269,416...81,308,734 		JBrowse link
G Prkn parkin RBR E3 ubiquitin protein ligase involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:12628165), (PMID:15728840), (PMID:16352719), (PMID:17512523)
GO_REF:0000107		 ParkinsonsUK-UCL
RGD
Ensembl		 PMID:12628165 PMID:15728840 PMID:16352719 PMID:17512523 GO_REF:0000024 GO_REF:0000107 NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555 		JBrowse link
G Rad18 RAD18 E3 ubiquitin protein ligase acts_upstream_of_or_within ISO (PMID:25023518) RGD PMID:25023518 NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069 		JBrowse link
G Rag1 recombination activating 1 involved_in ISO (MGI:3029666|PMID:14671314) RGD PMID:14671314 MGI:3029666 NCBI chr 3:87,917,061...87,928,158
Ensembl chr 3:87,917,004...87,928,291 		JBrowse link
G Rchy1 ring finger and CHY zinc finger domain containing 1 involved_in ISO (PMID:19483087) RGD PMID:19483087 NCBI chr14:16,113,263...16,129,017
Ensembl chr14:16,113,224...16,129,167 		JBrowse link
G Rnf10 ring finger protein 10 involved_in ISO
IEA		 (PMID:24105792)
GO_REF:0000107		 RGD
Ensembl		 PMID:24105792 GO_REF:0000107 NCBI chr12:41,341,708...41,375,505
Ensembl chr12:41,341,717...41,375,504 		JBrowse link
G Rnf11 ring finger protein 11 involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr 5:124,212,433...124,243,125
Ensembl chr 5:124,212,445...124,234,750 		JBrowse link
G Rnf112 ring finger protein 112 involved_in ISS
ISO
IEA		 GO_REF:0000024
(MGI:5779470|PMID:26212327)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:26212327 GO_REF:0000024 GO_REF:0000107 MGI:5779470 NCBI chr10:46,121,146...46,126,691
Ensembl chr10:46,121,148...46,126,699 		JBrowse link
G Rnf115 ring finger protein 115 involved_in ISO (PMID:16288031) RGD PMID:16288031 NCBI chr 2:184,262,087...184,329,839
Ensembl chr 2:184,262,371...184,329,823 		JBrowse link
G Rnf122 ring finger protein 122 involved_in ISO (PMID:20553626) RGD PMID:20553626 NCBI chr16:61,009,879...61,027,429
Ensembl chr16:61,009,879...61,027,448 		JBrowse link
G Rnf13 ring finger protein 13 involved_in ISS
ISO		 GO_REF:0000024
(MGI:3844769|PMID:19292867)		 UniProt
RGD		 PMID:19292867 GO_REF:0000024 MGI:3844769 NCBI chr 2:141,927,887...142,061,801
Ensembl chr 2:141,927,909...142,061,801 		JBrowse link
G Rnf133 ring finger protein 133 involved_in ISO (MGI:3852299|PMID:18574499) RGD PMID:18574499 MGI:3852299 NCBI chr 4:52,140,584...52,143,357
Ensembl chr 4:52,140,247...52,143,379 		JBrowse link
G rnf141 ring finger protein 141 involved_in ISO
IBA
IEA		 (PMID:24105792)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:24105792 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:164,933,972...164,957,081
Ensembl chr 1:164,931,077...164,957,118 		JBrowse link
G Rnf146 ring finger protein 146 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000104
(PMID:21478859)		 UniProt
RGD		 PMID:21478859 GO_REF:0000024 GO_REF:0000104 NCBI chr 1:28,458,864...28,475,758
Ensembl chr 1:28,458,887...28,475,923 		JBrowse link
G Rnf181 ring finger protein 181 involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr 4:104,414,586...104,421,433
Ensembl chr 4:104,414,605...104,421,309 		JBrowse link
G Rnf183 ring finger protein 183 involved_in ISO (PMID:29507230)
(MGI:6113025|PMID:29300766)		 RGD PMID:29300766 PMID:29507230 MGI:6113025 NCBI chr 5:75,877,111...75,886,253
Ensembl chr 5:75,876,003...75,886,191 		JBrowse link
G Rnf185 ring finger protein 185 involved_in ISS
IEA
ISO		 GO_REF:0000024
GO_REF:0000107
(PMID:24019521), (PMID:27485036)		 UniProt
Ensembl
RGD		 PMID:24019521 PMID:27485036 GO_REF:0000024 GO_REF:0000107 NCBI chr14:78,292,517...78,329,832
Ensembl chr14:78,292,516...78,329,864 		JBrowse link
G Rnf186 ring finger protein 186 involved_in ISO
IBA		 (PMID:23896122)
GO_REF:0000033		 RGD
GO_Central		 PMID:23896122 GO_REF:0000033 NCBI chr 5:151,210,492...151,211,716
Ensembl chr 5:151,210,492...151,211,716 		JBrowse link
G Rnf187 ring finger protein 187 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20852630)		 UniProt
RGD		 PMID:20852630 GO_REF:0000024 NCBI chr10:43,709,493...43,715,392
Ensembl chr10:43,702,357...43,716,157 		JBrowse link
G Rnf19b ring finger protein 19B involved_in ISO (PMID:27485036) RGD PMID:27485036 NCBI chr 5:141,406,085...141,431,376
Ensembl chr 5:141,406,118...141,431,380 		JBrowse link
G Rnf208 ring finger protein 208 involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr 3:8,057,808...8,059,721
Ensembl chr 3:8,043,685...8,059,844 		JBrowse link
G Rnf213 ring finger protein 213 involved_in ISO (PMID:21799892) RGD PMID:21799892 NCBI chr10:104,656,329...104,755,669
Ensembl chr10:104,656,883...104,757,918 		JBrowse link
G Rnf220 ring finger protein 220 involved_in ISO (MGI:4820696|PMID:20170641) RGD PMID:20170641 MGI:4820696 NCBI chr 5:130,739,173...130,961,386
Ensembl chr 5:130,739,183...130,961,418 		JBrowse link
G Rnf4 ring finger protein 4 involved_in IDA
IMP		 PMID:14987998 RGD
UniProt		 PMID:21857666 PMID:14987998 RGD:9831417, RGD:8554770 NCBI chr14:76,401,292...76,423,270
Ensembl chr14:76,401,299...76,422,566 		JBrowse link
G Rnf41 ring finger protein 41 involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr 7:838,160...876,869
Ensembl chr 7:838,203...865,511 		JBrowse link
G Rnf8 ring finger protein 8 involved_in ISO (PMID:22266820) RGD PMID:22266820 NCBI chr20:7,682,258...7,710,448
Ensembl chr20:7,682,322...7,708,491 		JBrowse link
G Rnft1 ring finger protein, transmembrane 1 involved_in ISO (PMID:27485036) RGD PMID:27485036 NCBI chr10:71,310,052...71,322,507
Ensembl chr10:71,310,104...71,323,778 		JBrowse link
G Sh3rf1 SH3 domain containing ring finger 1 involved_in ISS
ISO		 GO_REF:0000024
(PMID:20696164)		 UniProt
RGD		 PMID:20696164 GO_REF:0000024 NCBI chr16:28,735,522...28,901,261
Ensembl chr16:28,735,440...28,901,644 		JBrowse link
G Sh3rf2 SH3 domain containing ring finger 2 involved_in ISS
ISO		 GO_REF:0000024
(PMID:24130170)		 UniProt
RGD		 PMID:24130170 GO_REF:0000024 NCBI chr18:34,045,715...34,148,342
Ensembl chr18:34,046,879...34,146,856 		JBrowse link
G Sh3rf3 SH3 domain containing ring finger 3 involved_in ISO (PMID:20696164) RGD PMID:20696164 NCBI chr20:26,765,278...27,099,261
Ensembl chr20:26,765,015...27,099,257 		JBrowse link
G Stub1 STIP1 homology and U-box containing protein 1 involved_in ISO (PMID:16307917), (PMID:18042044) RGD PMID:16307917 PMID:18042044 NCBI chr10:14,850,765...14,853,046
Ensembl chr10:14,850,765...14,853,046 		JBrowse link
G Traf2 Tnf receptor-associated factor 2 involved_in ISO (PMID:20577214) RGD PMID:20577214 NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538 		JBrowse link
G Traf6 TNF receptor associated factor 6 acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:23776175)
GO_REF:0000107
(PMID:17135271), (PMID:18093978)		 RGD
Ensembl		 PMID:17135271 PMID:18093978 PMID:23776175 GO_REF:0000107 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Trim11 tripartite motif-containing 11 involved_in ISO (PMID:27498865) RGD PMID:27498865 NCBI chr10:43,758,299...43,771,138
Ensembl chr10:43,758,354...43,771,138 		JBrowse link
G Trim13 tripartite motif-containing 13 involved_in ISO
IEA		 (PMID:17314412)
GO_REF:0000107		 RGD
Ensembl		 PMID:17314412 GO_REF:0000107 NCBI chr15:35,733,548...35,772,676
Ensembl chr15:35,734,107...35,772,677 		JBrowse link
G Trim17 tripartite motif-containing 17 involved_in ISO (PMID:19358823) RGD PMID:19358823 NCBI chr10:43,743,111...43,750,929
Ensembl chr10:43,740,604...43,750,919 		JBrowse link
G Trim21 tripartite motif-containing 21 involved_in ISO (PMID:16880511) RGD PMID:16880511 NCBI chr 1:156,964,896...156,987,504
Ensembl chr 1:156,964,913...156,987,440 		JBrowse link
G Trim37 tripartite motif-containing 37 involved_in ISO
IBA		 (PMID:15885686)
GO_REF:0000033		 RGD
GO_Central		 PMID:15885686 GO_REF:0000033 NCBI chr10:71,943,384...72,075,563
Ensembl chr10:71,943,375...72,075,558 		JBrowse link
G Trim52 tripartite motif-containing 52 involved_in ISO (PMID:27667714) RGD PMID:27667714 NCBI chr15:82,886,237...82,924,611
Ensembl chr15:82,886,237...82,909,759 		JBrowse link
G Trim58 tripartite motif-containing 58 involved_in ISO (MGI:5908531|PMID:25241935) RGD PMID:25241935 MGI:5908531 NCBI chr10:43,022,933...43,038,984
Ensembl chr10:43,022,996...43,034,476 		JBrowse link
G Trim68 tripartite motif containing 68 involved_in ISO (PMID:18451177) RGD PMID:18451177 NCBI chr 1:157,114,044...157,127,494
Ensembl chr 1:157,114,044...157,127,477 		JBrowse link
G Trim71 tripartite motif containing 71 involved_in ISS
ISO		 GO_REF:0000024
(MGI:5319563|PMID:22508726)		 UniProt
RGD		 PMID:22508726 GO_REF:0000024 MGI:5319563 NCBI chr 8:114,193,439...114,250,807
Ensembl chr 8:114,199,187...114,250,807 		JBrowse link
G Ube2b ubiquitin-conjugating enzyme E2B involved_in ISO
IEA		 (PMID:19123975)
GO_REF:0000107		 RGD
Ensembl		 PMID:19123975 GO_REF:0000107 NCBI chr10:36,248,434...36,263,379
Ensembl chr10:36,248,438...36,264,665 		JBrowse link
G Ube2d2 ubiquitin-conjugating enzyme E2D 2 involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr18:27,364,325...27,406,322
Ensembl chr18:27,364,303...27,406,181 		JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 involved_in ISO (PMID:21068390) RGD PMID:21068390 NCBI chr 2:223,868,397...223,899,606
Ensembl chr 2:223,868,730...223,898,081 		JBrowse link
G Ube2t ubiquitin-conjugating enzyme E2T involved_in ISO (PMID:16916645), (PMID:19111657) RGD PMID:16916645 PMID:19111657 NCBI chr13:46,403,352...46,413,854
Ensembl chr13:46,403,375...46,414,835 		JBrowse link
G Ube3a ubiquitin protein ligase E3A involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr 1:110,070,260...110,161,675
Ensembl chr 1:110,070,480...110,157,250 		JBrowse link
G Ube3d ubiquitin protein ligase E3D involved_in ISO
IBA
IEA		 (PMID:15749827)
GO_REF:0000033
GO_REF:0000107		 RGD
GO_Central
Ensembl		 PMID:15749827 GO_REF:0000033 GO_REF:0000107 NCBI chr 8:87,245,503...87,413,104
Ensembl chr 8:87,245,589...87,413,057 		JBrowse link
G Ube4b ubiquitination factor E4B acts_upstream_of_or_within ISO (PMID:23509263) RGD PMID:23509263 NCBI chr 5:159,766,829...159,870,509
Ensembl chr 5:159,766,829...159,870,509 		JBrowse link
G Uhrf1 ubiquitin-like with PHD and ring finger domains 1 involved_in ISO
IEA		 (PMID:21745816)
GO_REF:0000107		 RGD
Ensembl		 PMID:21745816 GO_REF:0000107 NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631 		JBrowse link
G Uhrf2 ubiquitin like with PHD and ring finger domains 2 involved_in ISO (PMID:14741369) RGD PMID:14741369 NCBI chr 1:227,814,639...227,877,907
Ensembl chr 1:227,814,963...227,877,904 		JBrowse link
G Wwp2 WW domain containing E3 ubiquitin protein ligase 2 involved_in ISO (PMID:24105792) RGD PMID:24105792 NCBI chr19:35,346,826...35,471,251
Ensembl chr19:35,346,814...35,472,699 		JBrowse link
negative regulation of protein autoubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Marchf7 membrane associated ring-CH-type finger 7 involved_in ISS
ISO
IEA		 GO_REF:0000024
(PMID:29295817)
GO_REF:0000107		 UniProt
RGD
Ensembl		 PMID:29295817 GO_REF:0000024 GO_REF:0000107 NCBI chr 3:44,680,229...44,720,172
Ensembl chr 3:44,681,632...44,720,168 		JBrowse link
G Taf1 TATA-box binding protein associated factor 1 involved_in ISO (PMID:17237821) RGD PMID:17237821 NCBI chr  X:66,640,915...66,716,543
Ensembl chr  X:66,640,982...66,716,543 		JBrowse link
positive regulation of protein autoubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Lrrk2 leucine-rich repeat kinase 2 involved_in ISO (PMID:16352719) RGD PMID:16352719 NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703 		JBrowse link
G Mta1 metastasis associated 1 involved_in ISO
ISS
IEA		 (PMID:19805145)
GO_REF:0000024
GO_REF:0000107		 RGD
UniProt
Ensembl		 PMID:19805145 GO_REF:0000024 GO_REF:0000107 NCBI chr 6:132,178,608...132,217,641
Ensembl chr 6:132,178,853...132,217,641 		JBrowse link
G Rbx1 ring-box 1 involved_in ISO (PMID:14528312) RGD PMID:14528312 NCBI chr 7:112,976,863...113,001,051
Ensembl chr 7:112,990,835...113,001,051 		JBrowse link
regulation of protein autoubiquitination term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sash1 SAM and SH3 domain containing 1 acts_upstream_of_or_within ISO (PMID:23776175) RGD PMID:23776175 NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19692
    metabolic process 11455
      macromolecule metabolic process 9273
        protein metabolic process 4605
          protein modification process 2016
            post-translational protein modification 886
              protein modification by small protein conjugation or removal 849
                protein modification by small protein conjugation 757
                  protein ubiquitination 698
                    protein autoubiquitination 77
                      negative regulation of protein autoubiquitination 2
                      positive regulation of protein autoubiquitination 3
                      regulation of protein autoubiquitination + 6
paths to the root