The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
An ethyl ester resulting from the formal condensation of the carboxy group of 3-amino-4-(cyclohexylamino)benzoic acid with ethanol. It is a potent inhibitor of ferroptosis, a distinct non-apoptotic form of cell death caused by lipid peroxidation. It is also a radical-trapping antioxidant and has the ability to reduce the accumulation of lipid peroxides and chain-carrying peroxyl radicals.
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of ACSL4 protein]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of ACSL4 protein]; ferrostatin-1 inhibits the reaction [Acrolein results in increased expression of ACSL4 protein]; ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ACSL4 protein]; ferrostatin-1 inhibits the reaction [monobutyl phthalate results in increased expression of ACSL4 protein] ferrostatin-1 inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of ACSL4 protein]
ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of ATP2A2 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of ATP2A2 protein]
ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein] [ferrostatin-1 co-treated with sclareol] results in increased cleavage of CASP3 protein
[ferrostatin-1 co-treated with Benzene] results in increased expression of CYBB protein; ferrostatin-1 inhibits the reaction [Benzene results in increased expression of CYBB mRNA]
ferrostatin-1 affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol]; FXN protein affects the reaction [ferrostatin-1 affects the reaction [CYP2E1 protein affects the susceptibility to Ethanol]]
ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein] ferrostatin-1 inhibits the reaction [Silicon Dioxide results in increased expression of DDIT3 protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FTH1 protein] ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of FTH1 protein]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of FTH1 protein]; ferrostatin-1 inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of FTH1 protein]; ferrostatin-1 inhibits the reaction [Benzene results in increased expression of FTH1 mRNA]; ferrostatin-1 inhibits the reaction [Benzene results in increased expression of FTH1 protein]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of FTH1 protein]; ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of FTH1 protein]
ferrostatin-1 inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of FTL1 protein]; ferrostatin-1 inhibits the reaction [Benzene results in increased expression of FTL1 protein]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of FTL1 protein]
ferrostatin-1 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of GPT protein]; ferrostatin-1 inhibits the reaction [Matrines results in increased expression of GPT protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Acrolein results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Benzene results in decreased expression of GPX4 mRNA]; ferrostatin-1 inhibits the reaction [Benzene results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Busulfan results in decreased expression of and results in decreased activity of GPX4 protein]; ferrostatin-1 inhibits the reaction [Cisplatin results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of GPX4 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [monobutyl phthalate results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Silicon Dioxide results in decreased expression of GPX4 protein] [ferrostatin-1 co-treated with sclareol] results in decreased expression of GPX4 protein; ferrostatin-1 inhibits the reaction [1,3-dichloro-2-propanol results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [1-nitropyrene results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [erastin results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [shogaol results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [sodium arsenite results in decreased expression of GPX4 protein] ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of GPX4 mRNA]; ferrostatin-1 inhibits the reaction [Arsenic Trioxide results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [Fluorouracil results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein] ferrostatin-1 results in decreased expression of GPX4 protein ferrostatin-1 results in increased expression of GPX4 protein
ferrostatin-1 affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of HMOX1 protein] ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]
ferrostatin-1 inhibits the reaction [sodium arsenite results in increased expression of IL1B protein] ferrostatin-1 inhibits the reaction [IL1B protein results in decreased expression of COL2A1 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in decreased expression of GPX4 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in decreased expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in increased expression of MMP13 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in increased expression of NOS2 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in increased expression of P53 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of KCNA5 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of KCNA5 protein]
ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of KCNB1 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in decreased expression of KCNB1 protein]
ferrostatin-1 results in increased expression of NFATC2 protein ferrostatin-1 inhibits the reaction [Silicon Dioxide results in increased expression of NFATC2 protein]
ferrostatin-1 inhibits the reaction [Busulfan results in decreased expression of NFE2L2 protein] ferrostatin-1 inhibits the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of NFE2L2 protein]
ferrostatin-1 inhibits the reaction [Acrolein results in increased expression of PTGS2 protein]; ferrostatin-1 inhibits the reaction [Busulfan results in increased expression of PTGS2 mRNA]; ferrostatin-1 inhibits the reaction [Cisplatin results in increased expression of PTGS2 mRNA]; ferrostatin-1 inhibits the reaction [Cisplatin results in increased expression of PTGS2 protein]; ferrostatin-1 inhibits the reaction [Diethylhexyl Phthalate results in increased expression of PTGS2 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in increased expression of PTGS2 mRNA]; ferrostatin-1 inhibits the reaction [Ethanol results in increased expression of PTGS2 protein]; ferrostatin-1 inhibits the reaction [Matrines results in increased expression of PTGS2 mRNA]; ferrostatin-1 inhibits the reaction [Polymyxin B results in increased expression of PTGS2 protein] ferrostatin-1 inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein] ferrostatin-1 inhibits the reaction [IL1B protein results in increased expression of PTGS2 protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [IL1B protein results in decreased expression of SLC7A11 protein] ferrostatin-1 inhibits the reaction [Benzene results in decreased expression of SLC7A11 mRNA]; ferrostatin-1 inhibits the reaction [Benzene results in decreased expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [Cisplatin results in decreased expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SLC7A11 protein] ferrostatin-1 affects the reaction [7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide affects the expression of SLC7A11 protein]; ferrostatin-1 inhibits the reaction [1-nitropyrene results in decreased expression of SLC7A11 protein] ferrostatin-1 results in decreased expression of SLC7A11 protein
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SNCA protein]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of SNCA protein]
ferrostatin-1 inhibits the reaction [Fluorouracil results in increased expression of TFRC protein] ferrostatin-1 inhibits the reaction [Benzene results in increased expression of TFRC protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in decreased expression of TH protein]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of TH protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of TP53 protein]; ferrostatin-1 inhibits the reaction [Fluorouracil results in increased expression of TRP53 protein]
ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of ZFP36 mRNA]; ferrostatin-1 inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased expression of ZFP36 protein]
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