Mir145a (microRNA 145a) - Rat Genome Database

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Gene: Mir145a (microRNA 145a) Mus musculus
Analyze
Symbol: Mir145a
Name: microRNA 145a
RGD ID: 1608328
MGI Page MGI
Description: Acts upstream of or within with a positive effect on hematopoietic stem cell proliferation. Acts upstream of or within several processes, including blood vessel development; cellular response to estrogen stimulus; and cellular response to ethanol. Part of RISC complex. Is expressed in several structures, including alimentary system; central nervous system; dorsal root ganglion; lung; and oocyte. Orthologous to human MIR145 (microRNA 145).
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: mir-145a; Mir145; Mirn; Mirn145; mmu-mir-1; mmu-mir-145; mmu-mir-145a
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,780,896 - 61,780,965 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1861,780,896 - 61,780,965 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381861,647,825 - 61,647,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1861,647,825 - 61,647,894 (-)Ensemblmm10GRCm38
MGSCv371861,807,479 - 61,807,548 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1862,930,620 - 62,930,689 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.64NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aorta smooth muscle tissue morphogenesis  (IGI)
cardiac vascular smooth muscle cell differentiation  (IGI)
cellular response to amino acid stimulus  (IDA)
cellular response to estrogen stimulus  (IDA)
cellular response to ethanol  (IDA)
cellular response to hydroperoxide  (ISO)
cellular response to leukemia inhibitory factor  (IEP)
ectodermal cell differentiation  (ISO)
hematopoietic stem cell proliferation  (IGI)
long-term synaptic potentiation  (IEP)
mesodermal cell differentiation  (ISO)
miRNA-mediated gene silencing by inhibition of translation  (ISO)
miRNA-mediated gene silencing by mRNA destabilization  (ISO)
miRNA-mediated post-transcriptional gene silencing  (IEA)
negative regulation of angiogenesis  (ISO)
negative regulation of cardiac muscle cell apoptotic process  (ISO)
negative regulation of cell migration  (ISO)
negative regulation of cellular response to transforming growth factor beta stimulus  (ISO)
negative regulation of cholesterol efflux  (ISO)
negative regulation of epithelial to mesenchymal transition  (ISO)
negative regulation of extracellular matrix assembly  (ISO)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-16 production  (ISO)
negative regulation of SMAD protein signal transduction  (ISO)
negative regulation of somatic stem cell division  (ISO)
negative regulation of somatic stem cell population maintenance  (ISO)
negative regulation of transforming growth factor beta receptor signaling pathway  (ISO)
positive regulation of cellular response to hypoxia  (ISO)
positive regulation of interleukin-10 production  (ISO)
positive regulation of macrophage activation  (ISO)
positive regulation of macrophage differentiation  (ISO)
positive regulation of vascular associated smooth muscle cell differentiation involved in phenotypic switching  (ISO)
regulation of smooth muscle cell proliferation  (ISO)
response to alkaloid  (ISO)
response to ischemia  (ISO)
retina layer formation  (ISO)
transforming growth factor beta receptor signaling pathway  (IGI)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. MiR-145 facilitates proliferation and migration of endothelial progenitor cells and recanalization of arterial thrombosis in cerebral infarction mice via JNK signal pathway. Chen R, etal., Int J Clin Exp Pathol. 2015 Oct 1;8(10):13770-6. eCollection 2015.
2. Long noncoding RNA myocardial infarction associated transcript promotes the development of thoracic aortic by targeting microRNA-145 via the PI3K/Akt signaling pathway. Chen S, etal., J Cell Biochem. 2019 Sep;120(9):14405-14413. doi: 10.1002/jcb.28695. Epub 2019 Apr 15.
3. MicroRNA-145, a novel smooth muscle cell phenotypic marker and modulator, controls vascular neointimal lesion formation. Cheng Y, etal., Circ Res. 2009 Jul 17;105(2):158-66. doi: 10.1161/CIRCRESAHA.109.197517. Epub 2009 Jun 18.
4. miR-145 attenuates cardiac fibrosis through the AKT/GSK-3β/β-catenin signaling pathway by directly targeting SOX9 in fibroblasts. Cui S, etal., J Cell Biochem. 2021 Feb;122(2):209-221. doi: 10.1002/jcb.29843. Epub 2020 Sep 5.
5. Circulatory microRNA-145 expression is increased in cerebral ischemia. Gan CS, etal., Genet Mol Res. 2012 Jan 27;11(1):147-52. doi: 10.4238/2012.January.27.1.
6. Plasma Levels of microRNA-145 Are Associated with Severity of Coronary Artery Disease. Gao H, etal., PLoS One. 2015 May 4;10(5):e0123477. doi: 10.1371/journal.pone.0123477. eCollection 2015.
7. Long noncoding RNA MALAT1 mediates cardiac fibrosis in experimental postinfarct myocardium mice model. Huang S, etal., J Cell Physiol. 2019 Mar;234(3):2997-3006. doi: 10.1002/jcp.27117. Epub 2018 Aug 26.
8. MicroRNA-145 post-transcriptionally regulates the expression and function of P-glycoprotein in intestinal epithelial cells. Ikemura K, etal., Mol Pharmacol. 2013 Feb;83(2):399-405. doi: 10.1124/mol.112.081844. Epub 2012 Nov 19.
9. Circular RNA Sirtuin1 represses pulmonary artery smooth muscle cell proliferation, migration and autophagy to ameliorate pulmonary hypertension via targeting microRNA-145-5p/protein kinase-B3 axis. Jing X, etal., Bioengineered. 2022 Apr;13(4):8759-8771. doi: 10.1080/21655979.2022.2036302.
10. Associations Between miRNAs and Two Different Cancers: Breast and Colon. Kundaktepe BP, etal., Cancer Manag Res. 2020 Feb 7;12:871-879. doi: 10.2147/CMAR.S227628. eCollection 2020.
11. P38 MAPK Signaling Pathway Mediates Angiotensin II-Induced miR143/145 Gene Cluster Downregulation during Aortic Dissection Formation. Li B, etal., Ann Vasc Surg. 2017 Apr;40:262-273. doi: 10.1016/j.avsg.2016.09.016. Epub 2017 Feb 4.
12. Investigation of the clinical significance and prognostic value of microRNA-145 in human hepatocellular carcinoma. Li P, etal., Medicine (Baltimore). 2018 Dec;97(51):e13715. doi: 10.1097/MD.0000000000013715.
13. MicroRNA-145 protects cardiomyocytes against hydrogen peroxide (H(2)O(2))-induced apoptosis through targeting the mitochondria apoptotic pathway. Li R, etal., PLoS One. 2012;7(9):e44907. doi: 10.1371/journal.pone.0044907. Epub 2012 Sep 18.
14. Microrna-145 accelerates the inflammatory reaction through activation of NF-κB signaling in atherosclerosis cells and mice. Li S, etal., Biomed Pharmacother. 2018 Jul;103:851-857. doi: 10.1016/j.biopha.2018.03.173. Epub 2018 Apr 24.
15. Regulatory Mechanism of MicroRNA-145 in the Pathogenesis of Acute Aortic Dissection. Li T, etal., Yonsei Med J. 2019 Apr;60(4):352-359. doi: 10.3349/ymj.2019.60.4.352.
16. Effects of flavonoids on MicroRNA 145 regulation through Klf4 and myocardin in neointimal formation in vitro and in vivo. Lin CM, etal., J Nutr Biochem. 2018 Feb;52:27-35. doi: 10.1016/j.jnutbio.2017.08.016. Epub 2017 Sep 14.
17. Correlation between miR-21 and miR-145 and the incidence and prognosis of colorectal cancer. Liu Q, etal., J BUON. 2018 Jan-Feb;23(1):29-35.
18. Over-expression of microRNA-145 drives alterations in β-adrenergic signaling and attenuates cardiac remodeling in heart failure post myocardial infarction. Liu Z, etal., Aging (Albany NY). 2020 Jun 18;12(12):11603-11622. doi: 10.18632/aging.103320. Epub 2020 Jun 18.
19. MicroRNA-145 Protects against Myocardial Ischemia Reperfusion Injury via CaMKII-Mediated Antiapoptotic and Anti-Inflammatory Pathways. Liu Z, etal., Oxid Med Cell Longev. 2019 Sep 10;2019:8948657. doi: 10.1155/2019/8948657. eCollection 2019.
20. Overexpression of MicroRNA-145 Promotes Ascending Aortic Aneurysm Media Remodeling through TGF-β1. Pei H, etal., Eur J Vasc Endovasc Surg. 2015 Jan;49(1):52-9. doi: 10.1016/j.ejvs.2014.10.018.
21. Mouse MP Annotation Import Pipeline RGD automated import pipeline
22. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
23. Overexpression of microRNA-145 in atherosclerotic plaques from hypertensive patients. Santovito D, etal., Expert Opin Ther Targets. 2013 Mar;17(3):217-23. doi: 10.1517/14728222.2013.745512. Epub 2013 Jan 23.
24. miR-145-5p attenuates inflammatory response and apoptosis in myocardial ischemia-reperfusion injury by inhibiting (NADPH) oxidase homolog 1. Tan L, etal., Exp Anim. 2021 Aug 6;70(3):311-321. doi: 10.1538/expanim.20-0160. Epub 2021 Mar 4.
25. Clinicopathological significance of microRNA-31, -143 and -145 expression in colorectal cancer. Wang CJ, etal., Dis Markers. 2009;26(1):27-34. doi: 10.3233/DMA-2009-0601.
26. Long noncoding RNA H19 suppresses cardiac hypertrophy through the MicroRNA-145-3p/SMAD4 axis. Wang H, etal., Bioengineered. 2022 Feb;13(2):3826-3839. doi: 10.1080/21655979.2021.2017564.
27. LncRNA TUG1 Promotes Apoptosis, Invasion, and Angiogenesis of Retinal Endothelial Cells in Retinopathy of Prematurity via MiR-145-5p. Wang Y, etal., Front Med (Lausanne). 2022 Apr 4;9:803214. doi: 10.3389/fmed.2022.803214. eCollection 2022.
28. MicroRNA-145 is involved in endothelial cell dysfunction and acts as a promising biomarker of acute coronary syndrome. Wu S, etal., Eur J Med Res. 2020 Mar 17;25(1):2. doi: 10.1186/s40001-020-00403-8.
29. The miR-143/145 cluster reverses the regulation effect of KLF5 in smooth muscle cells with proliferation and contractility in intracranial aneurysm. Xu J, etal., Gene. 2018 Dec 30;679:266-273. doi: 10.1016/j.gene.2018.09.010. Epub 2018 Sep 7.
30. MicroRNA-145-5p targeting of TRIM2 mediates the apoptosis of retinal ganglion cells via the PI3K/AKT signaling pathway in glaucoma. Xu K, etal., J Gene Med. 2021 Nov;23(11):e3378. doi: 10.1002/jgm.3378. Epub 2021 Aug 10.
31. Downregulation of microRNA-145 may contribute to liver fibrosis in biliary atresia by targeting ADD3. Ye Y, etal., PLoS One. 2017 Sep 13;12(9):e0180896. doi: 10.1371/journal.pone.0180896. eCollection 2017.
32. Downregulation of miR143/145 gene cluster expression promotes the aortic media degeneration process via the TGF-β1 signaling pathway. Zhang M and Wang Z, Am J Transl Res. 2019 Jan 15;11(1):370-378. eCollection 2019.
33. Circulating MicroRNA-145 is Associated with Acute Myocardial Infarction and Heart Failure. Zhang M, etal., Chin Med J (Engl). 2017 5th Jan 2017;130(1):51-56. doi: 10.4103/0366-6999.196573.
34. Hypermethylation of the Micro-RNA 145 Promoter Is the Key Regulator for NLRP3 Inflammasome-Induced Activation and Plaque Formation. Zhong W, etal., JACC Basic Transl Sci. 2018 Sep 19;3(5):604-624. doi: 10.1016/j.jacbts.2018.06.004. eCollection 2018 Oct.
35. MicroRNA-145 inhibits hepatic stellate cell activation and proliferation by targeting ZEB2 through Wnt/β-catenin pathway. Zhou DD, etal., Mol Immunol. 2016 Jul;75:151-60. doi: 10.1016/j.molimm.2016.05.018. Epub 2016 Jun 9.
Additional References at PubMed
PMID:12007417   PMID:16369549   PMID:16381832   PMID:16882971   PMID:16943360   PMID:17369397   PMID:17604727   PMID:18346711   PMID:18452032   PMID:18791161   PMID:19091803   PMID:19559694  
PMID:19578358   PMID:19690389   PMID:19720868   PMID:19727952   PMID:19816508   PMID:19898489   PMID:20056748   PMID:20215419   PMID:20351064   PMID:20378849   PMID:20413612   PMID:20439489  
PMID:20487000   PMID:20548288   PMID:21037258   PMID:21159816   PMID:21267068   PMID:21371421   PMID:21441927   PMID:21505201   PMID:21571357   PMID:21673106   PMID:21799743   PMID:21822254  
PMID:22203953   PMID:22327366   PMID:22474293   PMID:22511778   PMID:22697078   PMID:22715469   PMID:22796494   PMID:22895360   PMID:22965997   PMID:23185045   PMID:23339192   PMID:23355420  
PMID:23430263   PMID:23457217   PMID:23624080   PMID:23637774   PMID:23716939   PMID:23886710   PMID:23986572   PMID:24001939   PMID:24135019   PMID:24140891   PMID:24166492   PMID:24732799  
PMID:24845504   PMID:24855947   PMID:24967703   PMID:25008143   PMID:25273883   PMID:25307343   PMID:25323858   PMID:25535917   PMID:25573853   PMID:25801897   PMID:25858512   PMID:26052659  
PMID:26438731   PMID:26450370   PMID:26586766   PMID:26632856   PMID:26683376   PMID:26849971   PMID:27179777   PMID:27239472   PMID:27626380   PMID:27878762   PMID:27951581   PMID:27956160  
PMID:28091538   PMID:28564582   PMID:28564633   PMID:28644441   PMID:29217510   PMID:29577879   PMID:29858716   PMID:29921375   PMID:29925839   PMID:29973593   PMID:30059491   PMID:30582454  
PMID:30651631   PMID:30941422   PMID:30973865   PMID:31081103   PMID:31219744   PMID:31425342   PMID:31431501   PMID:31709761   PMID:31982428   PMID:32138732   PMID:32337837   PMID:32513897  
PMID:32560812   PMID:32628810   PMID:32648361   PMID:32756009   PMID:32826455   PMID:32852406   PMID:32855642   PMID:32894532   PMID:33356812   PMID:33505358   PMID:33529466   PMID:33824281  
PMID:33859759   PMID:34022175   PMID:34273377   PMID:34523259   PMID:34792688   PMID:35034587   PMID:35802277   PMID:35989413   PMID:36450139   PMID:36510317   PMID:36656656   PMID:37081667  
PMID:37097437   PMID:37381989   PMID:37610521   PMID:37950842   PMID:38087452   PMID:38105235   PMID:38353742   PMID:38718921   PMID:38866991   PMID:39103885   PMID:39304875  


Genomics

Comparative Map Data
Mir145a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391861,780,896 - 61,780,965 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1861,780,896 - 61,780,965 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381861,647,825 - 61,647,894 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1861,647,825 - 61,647,894 (-)Ensemblmm10GRCm38
MGSCv371861,807,479 - 61,807,548 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1862,930,620 - 62,930,689 (-)NCBICelera
Cytogenetic Map18E1NCBI
cM Map1834.64NCBI
MIR145
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh385149,430,646 - 149,430,733 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl5149,430,646 - 149,430,733 (+)Ensemblhg38GRCh38
GRCh375148,810,209 - 148,810,296 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 365148,790,401 - 148,790,488 (+)NCBIBuild 36Build 36hg18NCBI36
Celera5144,892,189 - 144,892,276 (+)NCBICelera
Cytogenetic Map5q32NCBI
HuRef5143,956,545 - 143,956,632 (+)NCBIHuRef
CHM1_15148,242,644 - 148,242,731 (+)NCBICHM1_1
T2T-CHM13v2.05149,965,492 - 149,965,579 (+)NCBIT2T-CHM13v2.0
Mir145
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81857,369,983 - 57,370,070 (-)NCBIGRCr8GRCr8GRCr8
mRatBN7.21855,099,640 - 55,099,727 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1855,099,640 - 55,099,727 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1857,193,356 - 57,193,443 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01857,907,967 - 57,908,054 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01855,723,506 - 55,723,593 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01856,969,907 - 56,969,994 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1856,969,907 - 56,969,994 (-)Ensemblrn6Rnor6.0
Rnor_5.01856,198,820 - 56,198,907 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera1853,250,138 - 53,250,225 (-)NCBICelera
Cytogenetic Map18q12.1NCBI
MIR145
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1459,533,128 - 59,533,210 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl459,533,128 - 59,533,210 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha459,298,427 - 59,298,509 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0460,015,687 - 60,015,769 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl460,015,687 - 60,015,769 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1459,802,584 - 59,802,666 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0459,917,043 - 59,917,125 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0460,447,590 - 60,447,672 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
MIR145
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl2150,580,126 - 150,580,211 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.12150,580,126 - 150,580,211 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.22157,346,127 - 157,346,212 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Variants

.
Variants in Mir145a
3 total Variants
miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:34709
Count of gene targets:12890
Count of transcripts:22479
Interacting mature miRNAs:mmu-miR-145a-3p, mmu-miR-145a-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302163Bmd16_mbone mineral density 16 (mouse)Not determined182966791463668060Mouse
1302099Hdlq30_mHDL QTL 30 (mouse)Not determined185166830085668468Mouse
11252137Modvl5_mmodifier of vacuolated lens 5 (mouse)185105215685052311Mouse
12910791Pwgrq8_mpre-weaning growth rate QTL 8 (mouse)185802139969349142Mouse
1558803W3q16_mweight 3 weeks QTL 16 (mouse)Not determined186127244881491831Mouse
10412183Sstapa2_mSuseptibility to Staphylococus aureus infection 2 (mouse)Not determined185679463066952485Mouse
10412244Par5_mpulmonary adenoma resistance 5 (mouse)Not determined185166830085668468Mouse
1301400Lmr13_mleishmaniasis resistance 13 (mouse)Not determined182810938062109518Mouse
1301215Thcr_mT helper cell response (mouse)Not determined184513060468778777Mouse
1301853Heal9_mwound healing/regeneration 9 (mouse)Not determined185280527686805416Mouse
1302109Sluc28_msusceptibility to lung cancer 28 (mouse)Not determined185993532190720763Mouse
25823173Hrsq12_mhost response to SARS QTL 12, hemorrhage (mouse)182489588178339555Mouse
1357639Obsty4_mobesity 4 (mouse)Not determined183961991484638778Mouse
4140971Mbmq1_mmale body mass QTL 1 (mouse)Not determined5799028190720763Mouse
4142443Pgis1_mproteoglycan induced spondylitis 1 (mouse)Not determined185329102276914293Mouse
1301771Pcyts6_mplasmacytoma susceptibility 6 (mouse)Not determined183565863269658851Mouse
12880412V125Dq12_mvitamin D active form serum level QTL 12 (mouse)183023306764233067Mouse
1301902Hrtfm4_mheart failure modifier 4 (mouse)Not determined184331112077311343Mouse
1300685Scc5_mcolon tumor susceptibility 5 (mouse)Not determined183198848065988629Mouse
4141857Mhysq5_mmale hybrid sterility QTL 5 (mouse)Not determined2813060462130739Mouse
12880410V125Dq13_mvitamin D active form serum level QTL 13 (mouse)185643307190433071Mouse
4142239Idd21.2_minsulin dependent diabetes susceptibility 21.2 (mouse)Not determined186127244874562414Mouse
4142366Chlq10_mcirculating hormone level QTL 10 (mouse)Not determined183629102270291180Mouse
12050070Nabq2_mnasal bone morphology QTL 2 (mouse)183910367773103793Mouse
12880428V125Dq14_mvitamin D active form serum level QTL 14 (mouse)185743307190720763Mouse
1558782Orgwq9_morgan weight QTL 9 (mouse)Not determined186127244882604728Mouse
1357630Tgq1_mtriglyceride QTL 1 (mouse)Not determined185105215685052311Mouse
12880430Fgf23lq4_mFGF23 serum level QTL 4 (mouse)185643307190433071Mouse
11039492Ltpr8a_mLeishmania tropica response 8a (mouse)185918009290720763Mouse
11039493Ltpr8d_mLeishmania tropica response 8d (mouse)184687490380875042Mouse
12904745Carcdq2_mcardiac collagen deposition QTL 2 (mouse)184642328780423287Mouse
1357690Vtbt19_mvertebral trabecular bone trait 19 (mouse)Not determined183309104367091221Mouse
11039494Ltpr8b_mLeishmania tropica response 8b (mouse)184687490380875042Mouse
1301500Szs4_mseizure susceptibility 4 (mouse)Not determined185497587385514143Mouse
11039495Ltpr8c_mLeishmania tropica response 8c (mouse)185918009290720763Mouse
15039381Ltgq8_mliver triglyceride QTL 8 (mouse)183820656972206569Mouse
1302050Radpf4_mradiation pulmonary fibrosis 4 (mouse)Not determined185296615668778777Mouse
15039383Mvlq5_mmicrovesicular liver lesion QTL 5 (mouse)183820656972206569Mouse
4141132Eae18_mexperimental allergic encephalomyelitis susceptibility 18 (mouse)Not determined5759055982604728Mouse
38455998Cdtm1_mCD62L+ CD8 TM cells 1 (mouse)186013307280043215Mouse
11049564Lmr29_mleishmaniasis resistance 29 (mouse)185918009290720763Mouse
1357603Mom3_mmodifier of Min 3 (mouse)Not determined181403002367098962Mouse
1301353Lbw6_mlupus NZB x NZW 6 (mouse)Not determined185756233890720763Mouse
1301103Pgia11_mproteoglycan induced arthritis 11 (mouse)Not determined185991418490720763Mouse
15039384Liviq1_mliver inflammation QTL 1 (mouse)183820656972206569Mouse
27226720Tibw5_mtibia width 5, proximal, 10 week (mouse)185043306762633071Mouse
15039386Mvlq4_mmacrovesicular liver lesion QTL 4 (mouse)183820656972206569Mouse


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSMUST00000083658
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1861,780,896 - 61,780,965 (-)Ensembl
GRCm38.p6 Ensembl1861,647,825 - 61,647,894 (-)Ensembl
RefSeq Acc Id: NR_029557
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391861,780,896 - 61,780,965 (-)NCBI
GRCm381861,647,825 - 61,647,894 (-)ENTREZGENE
MGSCv371861,807,479 - 61,807,548 (-)RGD
Celera1862,930,620 - 62,930,689 (-)RGD
cM Map18 ENTREZGENE
Sequence:
Promoters
RGD ID:13677956
Promoter ID:EPDNEW_M23127
Type:single initiation site
Name:Mir145a_1
Description:Mus musculus microRNA 145a , microRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381861,647,826 - 61,647,886EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:2676830 AgrOrtholog
Ensembl Genes ENSMUSG00000065592 Ensembl, ENTREZGENE
Ensembl Transcript ENSMUST00000083658 ENTREZGENE
MGD MGI:2676830 ENTREZGENE
miRBase MI0000169 ENTREZGENE
NCBI Gene 387163 ENTREZGENE
PhenoGen Mir145a PhenoGen
RNAcentral URS00002D3C42 RNACentral
  URS0000527F89 RNACentral
  URS000075C4F5 RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-05-27 Mir145a  microRNA 145a  Mir145  microRNA 145  Symbol and/or name change 5135510 APPROVED