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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lancl1 | Rat | 1,2-dichloroethane | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of LANCL1 mRNA | CTD | PMID:28189721 and PMID:28960355 | Lancl1 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of LANCL1 mRNA | CTD | PMID:22206623 | Lancl1 | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of LANCL1 mRNA | CTD | PMID:22206623 | Lancl1 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Lancl1 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of LANCL1 mRNA | CTD | PMID:17555576 | Lancl1 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LANCL1 mRNA | CTD | PMID:17942748 | Lancl1 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of LANCL1 mRNA | CTD | PMID:17942748 | Lancl1 | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of LANCL1 mRNA | CTD | PMID:32145629 | Lancl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of LANCL1 mRNA | CTD | PMID:17942748 | Lancl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LANCL1 mRNA | CTD | PMID:33387578 | Lancl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lancl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LANCL1 mRNA | CTD | PMID:21570461 | Lancl1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LANCL1 mRNA | CTD | PMID:15328365 and PMID:17942748 | Lancl1 | Rat | 3,3',4,4',5-pentachlorobiphenyl | decreases expression | EXP | | 6480464 | 3 more ... | CTD | PMID:23196670 | Lancl1 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of LANCL1 mRNA | CTD | PMID:18648102 | Lancl1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of LANCL1 protein | CTD | PMID:34186270 | Lancl1 | Rat | aflatoxin B1 | decreases methylation | ISO | LANCL1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of LANCL1 gene | CTD | PMID:27153756 | Lancl1 | Rat | all-trans-retinoic acid | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of LANCL1 mRNA | CTD | PMID:33167477 | Lancl1 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of LANCL1 mRNA | CTD | PMID:16483693 | Lancl1 | Rat | antirheumatic drug | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of LANCL1 mRNA | CTD | PMID:24449571 | Lancl1 | Rat | aristolochic acid A | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of LANCL1 protein | CTD | PMID:33212167 | Lancl1 | Rat | arsenite(3-) | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LANCL1 mRNA] and arsenite inhibits the reaction [G3BP1 protein binds to LANCL1 protein] | CTD | PMID:32406909 | Lancl1 | Rat | benzo[a]pyrene | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of LANCL1 mRNA | CTD | PMID:22228805 | Lancl1 | Rat | beta-carotene | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA | CTD | PMID:24657404 | Lancl1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LANCL1 mRNA | CTD | PMID:25181051 | Lancl1 | Rat | bisphenol A | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of LANCL1 protein | CTD | PMID:34186270 | Lancl1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of LANCL1 mRNA | CTD | PMID:32145629 | Lancl1 | Rat | bisphenol A | affects expression | ISO | LANCL1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of LANCL1 mRNA | CTD | PMID:30903817 | Lancl1 | Rat | bisphenol A | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | bisphenol A promotes the reaction [LANCL1 protein binds to ESR1 protein] | CTD | PMID:27156127 | Lancl1 | Rat | Bisphenol B | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of LANCL1 protein | CTD | PMID:34186270 | Lancl1 | Rat | butanal | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | butyraldehyde results in decreased expression of LANCL1 mRNA | CTD | PMID:26079696 | Lancl1 | Rat | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of LANCL1 mRNA | CTD | PMID:19167457 | Lancl1 | Rat | cadmium atom | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LANCL1 mRNA | CTD | PMID:35301059 | Lancl1 | Rat | cadmium dichloride | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of LANCL1 protein | CTD | PMID:24527689 | Lancl1 | Rat | cadmium dichloride | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LANCL1 mRNA | CTD | PMID:35301059 | Lancl1 | Rat | CGP 52608 | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to LANCL1 gene] | CTD | PMID:28238834 | Lancl1 | Rat | cisplatin | affects response to substance | ISO | LANCL1 (Homo sapiens) | 6480464 | LANCL1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Lancl1 | Rat | clofibrate | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of LANCL1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of LANCL1 mRNA] | CTD | PMID:17585979 | Lancl1 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LANCL1 mRNA | CTD | PMID:17602206 | Lancl1 | Rat | cobalt dichloride | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of LANCL1 mRNA | CTD | PMID:19376846 | Lancl1 | Rat | copper(II) sulfate | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of LANCL1 mRNA | CTD | PMID:19549813 | Lancl1 | Rat | cyclosporin A | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of LANCL1 mRNA | CTD | PMID:20106945 and PMID:25562108 | Lancl1 | Rat | diazinon | decreases expression | EXP | | 6480464 | Diazinon results in decreased expression of LANCL1 mRNA | CTD | PMID:29108742 | Lancl1 | Rat | enzyme inhibitor | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of LANCL1 protein | CTD | PMID:23301498 | Lancl1 | Rat | epoxiconazole | decreases expression | ISO | Lancl1 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of LANCL1 mRNA | CTD | PMID:35436446 | Lancl1 | Rat | etoposide | affects response to substance | ISO | LANCL1 (Homo sapiens) | 6480464 | LANCL1 protein affects the susceptibility to Etoposide | CTD | PMID:16217747 | Lancl1 | Rat | folic acid | decreases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of LANCL1 mRNA | CTD | PMID:25629700 | Lancl1 | Rat | folic acid | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of LANCL1 mRNA | CTD | PMID:22206623 | Lancl1 | Rat | glyphosate | decreases expression | EXP | | 6480464 | Glyphosate results in decreased expression of LANCL1 mRNA | CTD | PMID:34906888 | Lancl1 | Rat | ivermectin | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of LANCL1 protein | CTD | PMID:32959892 | Lancl1 | Rat | leflunomide | increases expression | EXP | | 6480464 | leflunomide results in increased expression of LANCL1 mRNA | CTD | PMID:24136188 | Lancl1 | Rat | mercury atom | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Mercury results in decreased expression of LANCL1 mRNA | CTD | PMID:16823088 | Lancl1 | Rat | mercury(0) | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Mercury results in decreased expression of LANCL1 mRNA | CTD | PMID:16823088 | Lancl1 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of LANCL1 gene | CTD | PMID:35440735 | Lancl1 | Rat | N-nitrosodiethylamine | decreases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Diethylnitrosamine results in decreased expression of LANCL1 mRNA | CTD | PMID:17942915 | Lancl1 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of LANCL1 mRNA | CTD | PMID:17602206 | Lancl1 | Rat | N-nitrosodiethylamine | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | MET protein inhibits the reaction [Diethylnitrosamine results in decreased expression of LANCL1 mRNA] | CTD | PMID:17942915 | Lancl1 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of LANCL1 mRNA | CTD | PMID:24136188 | Lancl1 | Rat | paracetamol | multiple interactions | ISO | Lancl1 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of LANCL1 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of LANCL1 mRNA] | CTD | PMID:17585979 | Lancl1 | Rat | pirinixic acid | decreases expression | ISO | Lancl1 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of LANCL1 mRNA | CTD | PMID:17426115 | Lancl1 | Rat | SB 431542 | multiple interactions | ISO | LANCL1 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of LANCL1 protein | CTD | PMID:37664457 | Lancl1 | Rat | silicon dioxide | decreases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of LANCL1 mRNA | CTD | PMID:25895662 | Lancl1 | Rat | sodium arsenate | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | sodium arsenate results in increased expression of LANCL1 mRNA | CTD | PMID:30953684 | Lancl1 | Rat | sodium fluoride | increases expression | ISO | Lancl1 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of LANCL1 protein | CTD | PMID:28918527 | Lancl1 | Rat | sunitinib | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of LANCL1 mRNA | CTD | PMID:31533062 | Lancl1 | Rat | tamoxifen | affects expression | ISO | Lancl1 (Mus musculus) | 6480464 | Tamoxifen affects the expression of LANCL1 mRNA | CTD | PMID:17555576 | Lancl1 | Rat | taurine | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Taurine results in increased expression of LANCL1 mRNA | CTD | PMID:16579726 | Lancl1 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of LANCL1 mRNA | CTD | PMID:34492290 | Lancl1 | Rat | trichloroethene | increases expression | EXP | | 6480464 | Trichloroethylene results in increased expression of LANCL1 mRNA | CTD | PMID:33387578 | Lancl1 | Rat | triphenyl phosphate | affects expression | ISO | LANCL1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of LANCL1 mRNA | CTD | PMID:37042841 | Lancl1 | Rat | valproic acid | increases expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of LANCL1 mRNA | CTD | PMID:29154799 | Lancl1 | Rat | valproic acid | affects expression | ISO | Lancl1 (Mus musculus) | 6480464 | Valproic Acid affects the expression of LANCL1 mRNA | CTD | PMID:17292431 | Lancl1 | Rat | valproic acid | affects expression | ISO | LANCL1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of LANCL1 mRNA | CTD | PMID:25979313 | |