Lancl1 (LanC like glutathione S-transferase 1) - Rat Genome Database

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Gene: Lancl1 (LanC like glutathione S-transferase 1) Chinchilla lanigera
Analyze
Symbol: Lancl1
Name: LanC like glutathione S-transferase 1 (Ensembl:LanC like 1)
RGD ID: 8970579
Description: ENCODES a protein that exhibits glutathione binding (ortholog); glutathione transferase activity (ortholog); low-density lipoprotein particle receptor binding (ortholog); INVOLVED IN cellular detoxification (ortholog); G protein-coupled receptor signaling pathway (ortholog); ASSOCIATED WITH genetic disease (ortholog); Neurodevelopmental Disorders (ortholog); primary pulmonary hypertension (ortholog); FOUND IN plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: LanC lantibiotic synthetase component C-like 1 (bacterial); LanC like 1; lanC-like protein 1
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
NCBI Annotation Information: Annotation category: partial on reference assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,055,412 - 5,087,629 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554575,055,774 - 5,087,570 (+)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Lancl1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554575,055,412 - 5,087,629 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554575,055,774 - 5,087,570 (+)NCBIChiLan1.0ChiLan1.0
LANCL1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382210,431,251 - 210,477,584 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2210,427,131 - 210,477,652 (-)EnsemblGRCh38hg38GRCh38
GRCh372211,295,975 - 211,341,483 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362211,004,220 - 211,049,676 (-)NCBINCBI36Build 36hg18NCBI36
Build 342211,121,481 - 211,166,937NCBI
Celera2205,064,000 - 205,109,528 (-)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2203,142,033 - 203,187,544 (-)NCBIHuRef
CHM1_12211,302,098 - 211,347,624 (-)NCBICHM1_1
T2T-CHM13v2.02210,912,027 - 210,958,415 (-)NCBIT2T-CHM13v2.0
Lancl1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39167,039,676 - 67,078,049 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl167,039,676 - 67,078,031 (-)EnsemblGRCm39 Ensembl
GRCm38167,000,517 - 67,038,891 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl167,000,517 - 67,038,872 (-)EnsemblGRCm38mm10GRCm38
MGSCv37167,047,091 - 67,085,439 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,933,725 - 66,972,073 (-)NCBIMGSCv36mm8
Celera167,518,602 - 67,556,787 (-)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.75NCBI
Lancl1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,968,284 - 75,998,397 (-)NCBIGRCr8
mRatBN7.2968,515,052 - 68,548,646 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,518,574 - 68,548,628 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx977,007,766 - 77,037,685 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0982,136,694 - 82,166,613 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,543,344 - 80,573,309 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0974,018,192 - 74,048,098 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl974,014,656 - 74,048,244 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0973,260,328 - 73,293,876 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4965,799,079 - 65,828,986 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1965,946,062 - 65,975,968 (-)NCBI
Celera965,997,618 - 66,027,525 (-)NCBICelera
Cytogenetic Map9q32NCBI
LANCL1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213113,054,927 - 113,100,193 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B113,069,907 - 113,115,173 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,689,353 - 97,735,403 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B216,090,580 - 216,136,826 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B216,090,580 - 216,136,826 (-)Ensemblpanpan1.1panPan2
LANCL1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13718,209,162 - 18,246,100 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3718,212,137 - 18,246,354 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3719,093,044 - 19,127,151 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03718,150,458 - 18,184,557 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3718,147,382 - 18,184,592 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13718,102,975 - 18,137,066 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03718,065,451 - 18,099,512 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03718,080,246 - 18,114,053 (-)NCBIUU_Cfam_GSD_1.0
Lancl1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,675,567 - 166,708,402 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365865,917,413 - 5,952,952 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365865,917,470 - 5,950,101 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LANCL1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15113,111,370 - 113,149,050 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115113,111,427 - 113,149,181 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LANCL1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11096,144,156 - 96,191,023 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1096,144,541 - 96,191,030 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040103,172,642 - 103,217,667 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lancl1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247655,730,866 - 5,767,058 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247655,731,236 - 5,766,907 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000007622   ⟹   ENSCLAP00000007505
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554575,055,412 - 5,087,629 (+)Ensembl
RefSeq Acc Id: ENSCLAT00000007623   ⟹   ENSCLAP00000007506
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049554575,055,412 - 5,087,629 (+)Ensembl
RefSeq Acc Id: XM_013520773   ⟹   XP_013376227
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049554575,055,774 - 5,087,570 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs XP_013376227 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSCLAP00000007505
  ENSCLAP00000007505.1
  ENSCLAP00000007506.1
RefSeq Acc Id: XP_013376227   ⟸   XM_013520773
- UniProtKB: A0A8C2V467 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCLAP00000007505   ⟸   ENSCLAT00000007622
RefSeq Acc Id: ENSCLAP00000007506   ⟸   ENSCLAT00000007623


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000005272 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000007622 ENTREZGENE
  ENSCLAT00000007622.1 UniProtKB/TrEMBL
  ENSCLAT00000007623.1 UniProtKB/TrEMBL
Gene3D-CATH 1.50.10.10 UniProtKB/TrEMBL
InterPro 6hp_glycosidase-like_sf UniProtKB/TrEMBL
  LANC-like UniProtKB/TrEMBL
  LanC-like_prot_euk UniProtKB/TrEMBL
NCBI Gene Lancl1 ENTREZGENE
PANTHER GLUTATHIONE S-TRANSFERASE LANCL1 UniProtKB/TrEMBL
  LANC-LIKE PROTEIN UniProtKB/TrEMBL
Pfam LANC_like UniProtKB/TrEMBL
PRINTS LANCEUKARYTE UniProtKB/TrEMBL
  LANCSUPER UniProtKB/TrEMBL
SMART LANC_like UniProtKB/TrEMBL
Superfamily-SCOP LanC-like UniProtKB/TrEMBL
UniProt A0A8C2V467 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-21 Lancl1  LanC like glutathione S-transferase 1  Lancl1  LanC like 1  Symbol and/or name change 5135510 APPROVED
2016-08-03 Lancl1  LanC like 1    LanC lantibiotic synthetase component C-like 1 (bacterial)  Symbol and/or name change 5135510 APPROVED