Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dimethylhydrazine | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ABI2 mRNA | CTD | PMID:22206623 | 1,2-dimethylhydrazine | multiple interactions | ISO | Abi2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABI2 mRNA] | CTD | PMID:22206623 | 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of ABI2 mRNA | CTD | PMID:17557909 | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of ABI2 mRNA | CTD | PMID:29097150 | 17alpha-ethynylestradiol | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of ABI2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Abi2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ABI2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ABI2 mRNA | CTD | PMID:33387578 | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of ABI2 mRNA | CTD | PMID:21346803 | 2,5-hexanedione | increases expression | EXP | | 6480464 | 2 and 5-hexanedione results in increased expression of ABI2 mRNA | CTD | PMID:22952946 and PMID:27466211 | 2-butoxyethanol | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | n-butoxyethanol results in increased expression of ABI2 mRNA | CTD | PMID:19812364 | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABI2 mRNA | CTD | PMID:28628672 | 4,4'-diaminodiphenylmethane | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in decreased expression of ABI2 mRNA | CTD | PMID:18648102 | 5-fluorouracil | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | Fluorouracil results in decreased expression of ABI2 mRNA | CTD | PMID:19272435 | all-trans-retinoic acid | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ABI2 mRNA | CTD | PMID:23724009 | all-trans-retinoic acid | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of ABI2 mRNA | CTD | PMID:33167477 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ABI2 mRNA | CTD | PMID:16483693 | aristolochic acid A | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ABI2 mRNA | CTD | PMID:33212167 | arsane | affects methylation | ISO | ABI2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABI2 gene | CTD | PMID:25304211 | arsenic atom | affects methylation | ISO | ABI2 (Homo sapiens) | 6480464 | Arsenic affects the methylation of ABI2 gene | CTD | PMID:25304211 | arsenous acid | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ABI2 mRNA | CTD | PMID:22521957 | benzo[a]pyrene | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ABI2 mRNA | CTD | PMID:19770486 | benzo[a]pyrene | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ABI2 mRNA | CTD | PMID:32234424 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 | bis(2-ethylhexyl) phthalate | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ABI2 mRNA | CTD | PMID:31163220 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ABI2 mRNA | CTD | PMID:25181051 more ... | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of ABI2 gene | CTD | PMID:28505145 | bisphenol A | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABI2 mRNA | CTD | PMID:28628672 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ABI2 mRNA | CTD | PMID:25181051 | caffeine | increases phosphorylation | ISO | ABI2 (Homo sapiens) | 6480464 | Caffeine results in increased phosphorylation of ABI2 protein | CTD | PMID:35688186 | carbendazim | increases expression | EXP | | 6480464 | carbendazim results in increased expression of ABI2 mRNA | CTD | PMID:22952946 | chlorpyrifos | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of ABI2 mRNA | CTD | PMID:32715474 | copper(II) sulfate | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of ABI2 mRNA | CTD | PMID:19549813 | crocidolite asbestos | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | Asbestos and Crocidolite results in decreased expression of ABI2 mRNA | CTD | PMID:29279043 | cyclophosphamide | decreases expression | EXP | | 6480464 | Cyclophosphamide results in decreased expression of ABI2 mRNA | CTD | PMID:27466211 | cyclosporin A | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | Cyclosporine results in increased expression of ABI2 mRNA | CTD | PMID:19770486 | dexamethasone | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABI2 mRNA | CTD | PMID:28628672 | diarsenic trioxide | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of ABI2 mRNA | CTD | PMID:22521957 | dioxygen | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Oxygen deficiency results in increased expression of ABI2 mRNA | CTD | PMID:17175027 | dorsomorphin | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ABI2 mRNA | CTD | PMID:27188386 | ethanol | affects splicing | ISO | Abi2 (Mus musculus) | 6480464 | Ethanol affects the splicing of ABI2 mRNA | CTD | PMID:30319688 | folic acid | multiple interactions | ISO | Abi2 (Mus musculus) | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABI2 mRNA] | CTD | PMID:22206623 | FR900359 | affects phosphorylation | ISO | ABI2 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of ABI2 protein | CTD | PMID:37730182 | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ABI2 mRNA | CTD | PMID:33387578 | indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABI2 mRNA | CTD | PMID:22129741 | indometacin | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in decreased expression of ABI2 mRNA | CTD | PMID:28628672 | irinotecan | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Irinotecan results in decreased expression of ABI2 mRNA | CTD | PMID:20185912 | ivermectin | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ABI2 protein | CTD | PMID:32959892 | lithium chloride | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Lithium Chloride results in decreased expression of ABI2 mRNA | CTD | PMID:23527032 | maneb | multiple interactions | ISO | Abi2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ABI2 mRNA | CTD | PMID:36117858 | manganese atom | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Manganese results in increased expression of ABI2 mRNA | CTD | PMID:17175027 | manganese(0) | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Manganese results in increased expression of ABI2 mRNA | CTD | PMID:17175027 | manganese(II) chloride | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | manganese chloride results in increased expression of ABI2 mRNA | CTD | PMID:17175027 | N-methyl-4-phenylpyridinium | increases expression | EXP | | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of ABI2 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | Diethylnitrosamine results in increased expression of ABI2 mRNA | CTD | PMID:24535843 | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABI2 mRNA | CTD | PMID:22129741 | paracetamol | affects expression | ISO | Abi2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of ABI2 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of ABI2 mRNA | CTD | PMID:22230336 | paraquat | multiple interactions | ISO | Abi2 (Mus musculus) | 6480464 | [Maneb co-treated with Paraquat] results in decreased expression of ABI2 mRNA | CTD | PMID:36117858 | phenobarbital | affects expression | ISO | Abi2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of ABI2 mRNA | CTD | PMID:23091169 | pirinixic acid | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of ABI2 mRNA | CTD | PMID:23811191 | SB 431542 | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 and PMID:37664457 | sodium arsenite | affects expression | ISO | ABI2 (Homo sapiens) | 6480464 | sodium arsenite affects the expression of ABI2 mRNA | CTD | PMID:29319823 | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of ABI2 mRNA | CTD | PMID:19281266 | sunitinib | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of ABI2 mRNA | CTD | PMID:31533062 | tetrachloromethane | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of ABI2 mRNA | CTD | PMID:17484886 | tetrachloromethane | increases expression | ISO | Abi2 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of ABI2 mRNA | CTD | PMID:27339419 and PMID:31919559 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ABI2 mRNA | CTD | PMID:34492290 | triptonide | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | triptonide results in decreased expression of ABI2 mRNA | CTD | PMID:33045310 | troglitazone | decreases expression | ISO | Abi2 (Mus musculus) | 6480464 | troglitazone results in decreased expression of ABI2 mRNA | CTD | PMID:28973697 | valproic acid | increases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ABI2 mRNA | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | ABI2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ABI2 mRNA | CTD | PMID:23179753 and PMID:26272509 | valproic acid | multiple interactions | ISO | ABI2 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ABI2 mRNA | CTD | PMID:27188386 | |