Slco3a1 (solute carrier organic anion transporter family, member 3a1) - Rat Genome Database

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Gene: Slco3a1 (solute carrier organic anion transporter family, member 3a1) Rattus norvegicus
Analyze
Symbol: Slco3a1
Name: solute carrier organic anion transporter family, member 3a1
RGD ID: 620227
Description: Predicted to enable prostaglandin transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Involved in prostaglandin transport. Predicted to be located in basal plasma membrane. Predicted to be active in basolateral plasma membrane. Orthologous to human SLCO3A1 (solute carrier organic anion transporter family member 3A1); INTERACTS WITH 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: OATP-D; organic anion-transporting polypeptide D; prostaglandin transporter subtype 2; Slc21a11; sodium-independent organic anion transporter D; solute carrier family 21 (organic anion transporter), member 11; solute carrier family 21 member 11; solute carrier organic anion transporter family member 3A1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Is Marker For: Strains:   SHRSP.WKY-(Slco3a1-D1Rat106)/IzmTkyo  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,516,037 - 137,797,836 (-)NCBIGRCr8
mRatBN7.21128,106,232 - 128,388,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,106,228 - 128,387,925 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,062,978 - 136,336,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01143,233,107 - 143,506,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,101,551 - 136,374,041 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01135,790,854 - 136,073,640 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,790,810 - 136,073,540 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01136,793,300 - 137,070,909 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,580,126 - 130,077,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11129,658,468 - 130,155,453 (-)NCBI
Celera1120,235,201 - 120,503,802 (-)NCBICelera
Cytogenetic Map1q31NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
3-iodothyronamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
all-trans-retinoic acid  (ISO)
amosite asbestos  (ISO)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzylpenicillin  (ISO)
beta-lapachone  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP)
cadmium dichloride  (EXP)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chlordecone  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
crocidolite asbestos  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
estrone 3-sulfate  (ISO)
ethanol  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
fluorescein (lactone form)  (ISO)
folic acid  (ISO)
fonofos  (ISO)
gentamycin  (EXP)
glyphosate  (ISO)
indoxyl sulfate  (ISO)
isoprenaline  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
manganese(II) chloride  (EXP)
methoxychlor  (EXP)
microcystin-LR  (EXP)
Muraglitazar  (EXP)
ozone  (ISO)
paracetamol  (EXP,ISO)
parathion  (ISO)
potassium chromate  (ISO)
progesterone  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
simvastatin hydroxy acid  (ISO)
sodium arsenite  (ISO)
sulforaphane  (ISO)
terbufos  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
titanium dioxide  (ISO)
toluene  (EXP)
triphenyl phosphate  (ISO)
troglitazone  (EXP)
undecane  (EXP)
valproic acid  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Molecular characterization of human and rat organic anion transporter OATP-D. Adachi H, etal., Am J Physiol Renal Physiol 2003 Dec;285(6):F1188-97.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:21278488   PMID:24945726  


Genomics

Comparative Map Data
Slco3a1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,516,037 - 137,797,836 (-)NCBIGRCr8
mRatBN7.21128,106,232 - 128,388,043 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1128,106,228 - 128,387,925 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1136,062,978 - 136,336,526 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01143,233,107 - 143,506,677 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01136,101,551 - 136,374,041 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01135,790,854 - 136,073,640 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1135,790,810 - 136,073,540 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01136,793,300 - 137,070,909 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41129,580,126 - 130,077,110 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11129,658,468 - 130,155,453 (-)NCBI
Celera1120,235,201 - 120,503,802 (-)NCBICelera
Cytogenetic Map1q31NCBI
SLCO3A1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381591,853,708 - 92,172,435 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1591,853,708 - 92,172,435 (+)EnsemblGRCh38hg38GRCh38
GRCh371592,396,938 - 92,715,665 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361590,197,950 - 90,507,783 (+)NCBINCBI36Build 36hg18NCBI36
Build 341590,197,949 - 90,507,783NCBI
Celera1568,809,625 - 69,127,530 (+)NCBICelera
Cytogenetic Map15q26.1NCBI
HuRef1568,535,792 - 68,852,636 (+)NCBIHuRef
CHM1_11592,238,177 - 92,556,655 (+)NCBICHM1_1
T2T-CHM13v2.01589,615,458 - 89,934,870 (+)NCBIT2T-CHM13v2.0
Slco3a1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39773,925,166 - 74,204,528 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl773,925,167 - 74,204,528 (-)EnsemblGRCm39 Ensembl
GRCm38774,275,418 - 74,554,780 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl774,275,419 - 74,554,780 (-)EnsemblGRCm38mm10GRCm38
MGSCv37781,420,304 - 81,699,666 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36774,148,931 - 74,428,293 (-)NCBIMGSCv36mm8
Celera771,722,299 - 72,002,017 (-)NCBICelera
Cytogenetic Map7D1NCBI
cM Map742.95NCBI
Slco3a1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541620,186,940 - 20,483,958 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541620,186,940 - 20,483,844 (+)NCBIChiLan1.0ChiLan1.0
SLCO3A1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21681,399,080 - 81,720,058 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11585,099,736 - 85,420,671 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01570,537,924 - 70,858,714 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11589,735,202 - 90,055,251 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1589,739,022 - 90,054,678 (+)Ensemblpanpan1.1panPan2
SLCO3A1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1347,927,280 - 48,233,666 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl347,927,664 - 48,233,703 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha350,628,974 - 50,868,877 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0348,346,093 - 48,649,188 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl348,346,095 - 48,649,226 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1347,847,277 - 48,150,531 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0348,078,812 - 48,381,929 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0348,420,025 - 48,723,118 (-)NCBIUU_Cfam_GSD_1.0
Slco3a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640135,491,779 - 135,786,720 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648310,547,687 - 10,778,752 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648310,554,049 - 10,778,662 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLCO3A1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl786,777,920 - 87,103,309 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1786,777,919 - 87,103,316 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2792,719,394 - 93,045,275 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLCO3A1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12910,418,938 - 10,735,503 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605935,952,514 - 36,274,116 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slco3a1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476811,536,168 - 11,855,331 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476811,537,311 - 11,855,224 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slco3a1
2325 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:51
Count of miRNA genes:48
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000043854
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61442Strs1Sensitivity to stroke QTL 17.4cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)1121767634166767634Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
1598866Bp287Blood pressure QTL 2875.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
9590300Scort16Serum corticosterone level QTL 164.390.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)1103111621148111621Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
1598850Bp297Blood pressure QTL 2972.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121006655166006655Rat
631570Bp94Blood pressure QTL 940.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123479780142990467Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
152025232Bw192Body weight QTL 1923.93body mass (VT:0001259)1117917486196963478Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
61346Rf2Renal disease susceptibility QTL 23.7urine protein amount (VT:0005160)urine protein level (CMO:0000591)199267916144267916Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
2317833Alcrsp19Alcohol response QTL 1912.40.001response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
1641897Alcrsp1Alcohol response QTL 1response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)1100979852145979852Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
9685799Bp375Blood pressure QTL 375arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
2293140Bp313Blood pressure QTL 313arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1121833674166833674Rat
9685802Bp376Blood pressure QTL 376arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1126540680171540680Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat
61370Mcs3Mammary carcinoma susceptibility QTL 32.15mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1102268556147268556Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631496Bp97Blood pressure QTL 973.08arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1106047847151047847Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
2303591Gluco41Glucose level QTL 412blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1102168504147168504Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
2313060Bss71Bone structure and strength QTL 712.60.0001long bone metaphysis morphology trait (VT:0000133)tibia midshaft total cross-sectional area (CMO:0001715)1118944747163944747Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
61399Tcat1Tongue tumor resistance QTL 13.3tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 5 mm (CMO:0001879)199267916144267916Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
634348Bp138Blood pressure QTL 138arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501168883176Rat
8694370Bw154Body weight QTL 1548.910.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)1103111621148111621Rat
1354623Rf46Renal function QTL 463.8blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)1102813953151162766Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
631654Bp107Blood pressure QTL 107arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1125611501170611501Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
152025212Bw190Body weight QTL 1905.7body mass (VT:0001259)1123556856196963478Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
2325726Eae30Experimental allergic encephalomyelitis QTL 30nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)1123053310128593844Rat

Markers in Region
D1Got113  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21128,354,401 - 128,354,489 (+)MAPPERmRatBN7.2
Rnor_6.01136,040,289 - 136,040,376NCBIRnor6.0
Rnor_5.01137,037,664 - 137,037,751UniSTSRnor5.0
RGSC_v3.41130,043,124 - 130,043,212RGDRGSC3.4
RGSC_v3.41130,043,125 - 130,043,212UniSTSRGSC3.4
RGSC_v3.11130,121,468 - 130,121,555RGD
Celera1120,470,627 - 120,470,714UniSTS
RH 3.4 Map11004.6UniSTS
RH 3.4 Map11004.6RGD
RH 2.0 Map1657.4RGD
Cytogenetic Map1q31UniSTS
D1Mco53  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21128,319,846 - 128,320,087 (+)MAPPERmRatBN7.2
Rnor_6.01136,004,907 - 136,005,145NCBIRnor6.0
Rnor_5.01137,004,640 - 137,004,878UniSTSRnor5.0
RGSC_v3.41130,009,733 - 130,009,971UniSTSRGSC3.4
Celera1120,436,880 - 120,437,118UniSTS
Cytogenetic Map1q31UniSTS
BF387901  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21128,116,921 - 128,117,134 (+)MAPPERmRatBN7.2
Rnor_6.01135,801,539 - 135,801,751NCBIRnor6.0
Rnor_5.01136,803,985 - 136,804,197UniSTSRnor5.0
RGSC_v3.41129,581,864 - 129,582,076UniSTSRGSC3.4
Celera1120,236,939 - 120,237,151UniSTS
RH 3.4 Map1996.5UniSTS
Cytogenetic Map1q31UniSTS


Related Rat Strains
The following Strains have been annotated to Slco3a1
SHRSP.WKY-(Slco3a1-D1Rat106)/IzmTkyo    


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000043854   ⟹   ENSRNOP00000049659
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,799,801 - 136,073,483 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000075893
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,812,970 - 136,073,540 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000076340   ⟹   ENSRNOP00000068179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1135,799,750 - 136,073,540 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082564   ⟹   ENSRNOP00000074908
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1128,106,228 - 128,387,925 (-)Ensembl
Rnor_6.0 Ensembl1135,790,810 - 136,073,496 (-)Ensembl
RefSeq Acc Id: NM_177481   ⟹   NP_803434
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,516,037 - 137,797,836 (-)NCBI
mRatBN7.21128,106,232 - 128,388,043 (-)NCBI
Rnor_6.01135,799,801 - 136,073,483 (-)NCBI
Rnor_5.01136,793,300 - 137,070,909 (-)NCBI
RGSC_v3.41129,580,126 - 130,077,110 (-)RGD
Celera1120,235,201 - 120,503,802 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_803434 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAK15063 (Get FASTA)   NCBI Sequence Viewer  
  EDM08519 (Get FASTA)   NCBI Sequence Viewer  
  EDM08520 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000074908.2
GenBank Protein Q99N02 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_803434   ⟸   NM_177481
- Sequence:
Ensembl Acc Id: ENSRNOP00000049659   ⟸   ENSRNOT00000043854
Ensembl Acc Id: ENSRNOP00000074908   ⟸   ENSRNOT00000082564
Ensembl Acc Id: ENSRNOP00000068179   ⟸   ENSRNOT00000076340
Protein Domains
Kazal-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99N02-F1-model_v2 AlphaFold Q99N02 1-710 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690124
Promoter ID:EPDNEW_R642
Type:multiple initiation site
Name:Slco3a1_1
Description:solute carrier organic anion transporter family, member 3a1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01136,073,638 - 136,073,698EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620227 AgrOrtholog
BioCyc Gene G2FUF-58868 BioCyc
Ensembl Genes ENSRNOG00000032798 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000082564.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Kazal_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kazal_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MFS_trans_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:140915 UniProtKB/Swiss-Prot
NCBI Gene 140915 ENTREZGENE
PANTHER PTHR11388 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SOLUTE CARRIER ORGANIC ANION TRANSPORTER FAMILY MEMBER 3A1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Kazal_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  OATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Slco3a1 PhenoGen
PROSITE KAZAL_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032798 RatGTEx
Superfamily-SCOP SSF100895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF103473 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2K992_RAT UniProtKB/TrEMBL
  A6JBZ2_RAT UniProtKB/TrEMBL
  A6JBZ3_RAT UniProtKB/TrEMBL
  Q99N02 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Slco3a1  solute carrier organic anion transporter family, member 3a1  Slc21a11  solute carrier family 21 (organic anion transporter), member 11  Symbol and Name updated 1299863 APPROVED
2002-08-07 Slc21a11  solute carrier family 21 (organic anion transporter), member 11      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression protein is expressed in the vascular, renal, and reproductive system 737652