Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rpe | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Rpe (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of RPE mRNA | CTD | PMID:22206623 | Rpe | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rpe (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RPE mRNA | CTD | PMID:19770486 | Rpe | Rat | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Rpe | Rat | 2-methylcholine | affects expression | ISO | RPE (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RPE mRNA | CTD | PMID:21179406 | Rpe | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Rpe (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of RPE mRNA | CTD | PMID:18648102 | Rpe | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | RPE (Homo sapiens) | 6480464 | bisphenol S results in increased expression of RPE mRNA | CTD | PMID:31121516 | Rpe | Rat | 4,4'-sulfonyldiphenol | increases methylation | ISO | RPE (Homo sapiens) | 6480464 | bisphenol S results in increased methylation of RPE gene | CTD | PMID:31601247 | Rpe | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Rpe (Mus musculus) | 6480464 | Fenretinide results in decreased expression of RPE mRNA | CTD | PMID:28973697 | Rpe | Rat | acrolein | multiple interactions | ISO | RPE (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of RPE mRNA | CTD | PMID:32845096 | Rpe | Rat | aflatoxin B1 | increases expression | ISO | Rpe (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of RPE mRNA | CTD | PMID:19770486 | Rpe | Rat | all-trans-retinoic acid | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RPE mRNA | CTD | PMID:21934132 | Rpe | Rat | all-trans-retinoic acid | increases expression | ISO | RPE (Homo sapiens) | 6480464 | Tretinoin results in increased expression of RPE mRNA | CTD | PMID:33167477 | Rpe | Rat | aristolochic acid A | increases expression | ISO | RPE (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of RPE protein | CTD | PMID:33212167 | Rpe | Rat | aristolochic acid A | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of RPE mRNA | CTD | PMID:33212167 | Rpe | Rat | benzo[a]pyrene | decreases expression | ISO | Rpe (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of RPE mRNA | CTD | PMID:19770486 | Rpe | Rat | benzo[a]pyrene | increases expression | ISO | Rpe (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of RPE mRNA | CTD | PMID:22228805 | Rpe | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RPE mRNA | CTD | PMID:25181051 | Rpe | Rat | bisphenol A | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RPE mRNA | CTD | PMID:29275510 | Rpe | Rat | bisphenol F | increases expression | ISO | RPE (Homo sapiens) | 6480464 | bisphenol F results in increased expression of RPE mRNA | CTD | PMID:31121516 | Rpe | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of RPE mRNA | CTD | PMID:24136188 | Rpe | Rat | cadmium dichloride | increases expression | ISO | RPE (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of RPE protein | CTD | PMID:24527689 | Rpe | Rat | cobalt dichloride | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of RPE mRNA | CTD | PMID:19376846 | Rpe | Rat | dicrotophos | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RPE mRNA | CTD | PMID:28302478 | Rpe | Rat | doxorubicin | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RPE mRNA | CTD | PMID:29803840 | Rpe | Rat | ethanol | affects expression | ISO | Rpe (Mus musculus) | 6480464 | Ethanol affects the expression of RPE mRNA | CTD | PMID:30319688 | Rpe | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of RPE mRNA | CTD | PMID:24136188 | Rpe | Rat | folic acid | decreases expression | ISO | Rpe (Mus musculus) | 6480464 | Folic Acid results in decreased expression of RPE mRNA | CTD | PMID:25629700 | Rpe | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of RPE mRNA | CTD | PMID:27387713 | Rpe | Rat | hydrogen peroxide | affects expression | ISO | RPE (Homo sapiens) | 6480464 | Hydrogen Peroxide affects the expression of RPE mRNA | CTD | PMID:20044591 | Rpe | Rat | hydrogen peroxide | increases expression | ISO | RPE (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of RPE mRNA | CTD | PMID:18951874 | Rpe | Rat | ivermectin | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RPE protein | CTD | PMID:32959892 | Rpe | Rat | nickel atom | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Nickel results in decreased expression of RPE mRNA | CTD | PMID:23195993 | Rpe | Rat | ochratoxin A | decreases expression | EXP | | 6480464 | ochratoxin A results in decreased expression of RPE mRNA | CTD | PMID:22124623 | Rpe | Rat | ozone | multiple interactions | ISO | RPE (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with Ozone] results in increased expression of RPE mRNA | CTD | PMID:32845096 | Rpe | Rat | paracetamol | affects expression | ISO | Rpe (Mus musculus) | 6480464 | Acetaminophen affects the expression of RPE mRNA | CTD | PMID:17562736 | Rpe | Rat | paracetamol | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of RPE mRNA | CTD | PMID:21420995 | Rpe | Rat | phenytoin | increases expression | EXP | | 6480464 | Phenytoin results in increased expression of RPE mRNA | CTD | PMID:20345932 | Rpe | Rat | quercetin | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | Quercetin results in decreased expression of RPE mRNA | CTD | PMID:21632981 | Rpe | Rat | resveratrol | multiple interactions | ISO | RPE (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of RPE mRNA | CTD | PMID:23557933 | Rpe | Rat | sodium arsenite | decreases expression | ISO | RPE (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RPE mRNA | CTD | PMID:38568856 | Rpe | Rat | sunitinib | increases expression | ISO | RPE (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RPE mRNA | CTD | PMID:31533062 | Rpe | Rat | titanium dioxide | decreases methylation | ISO | Rpe (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RPE gene | CTD | PMID:35295148 | Rpe | Rat | triphenyl phosphate | affects expression | ISO | RPE (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RPE mRNA | CTD | PMID:37042841 | Rpe | Rat | triptonide | affects expression | ISO | Rpe (Mus musculus) | 6480464 | triptonide affects the expression of RPE mRNA | CTD | PMID:33045310 | Rpe | Rat | valproic acid | increases expression | ISO | RPE (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RPE mRNA | CTD | PMID:23179753 | |