Rpe (ribulose-5-phosphate-3-epimerase) - Rat Genome Database

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Gene: Rpe (ribulose-5-phosphate-3-epimerase) Heterocephalus glaber
Analyze
Symbol: Rpe
Name: ribulose-5-phosphate-3-epimerase
RGD ID: 18902732
Description: ENCODES a protein that exhibits carbohydrate binding (ortholog); D-ribulose-phosphate 3-epimerase activity (ortholog); identical protein binding (ortholog); INVOLVED IN pentose-phosphate shunt (ortholog); pentose-phosphate shunt, non-oxidative branch (ortholog); PARTICIPATES IN pentose phosphate pathway; pentose phosphate pathway - non-oxidative phase; ribose 5-phosphate isomerase deficiency pathway; ASSOCIATED WITH Neurodevelopmental Disorders (ortholog); primary pulmonary hypertension (ortholog); trichorhinophalangeal syndrome type I (ortholog); FOUND IN cytosol (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: Ribulose-phosphate 3-epimerase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247656,205,972 - 6,222,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247656,188,964 - 6,222,580 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-RatNeurodevelopmental Disorders  ISORPE (Homo sapiens)8554872ClinVar Annotator: match by term: Neurodevelopmental disorderClinVarPMID:25741868
RpeNaked Mole-Ratprimary pulmonary hypertension  ISORPE (Homo sapiens)8554872ClinVar Annotator: match by term: Primary pulmonary hypertensionClinVarPMID:28492532 and PMID:31727138
RpeNaked Mole-Rattrichorhinophalangeal syndrome type I  ISORPE (Homo sapiens)8554872ClinVar Annotator: match by term: Trichorhinophalangeal dysplasia type IClinVarPMID:25741868


Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-Ratcarbohydrate metabolic process involved_inIEAInterPro:IPR000056150520179 InterProGO_REF:0000002
RpeNaked Mole-Ratpentose-phosphate shunt  ISORpe (Rattus norvegicus)9068941 RGDPMID:2843500 and REF_RGD_ID:1599574
RpeNaked Mole-Ratpentose-phosphate shunt involved_inIEAInterPro:IPR026019150520179 InterProGO_REF:0000002
RpeNaked Mole-Ratpentose-phosphate shunt involved_inIEAUniProtKB:Q8VEE0 and ensembl:ENSMUSP00000027157150520179 EnsemblGO_REF:0000107
RpeNaked Mole-Ratpentose-phosphate shunt, non-oxidative branch  ISORpe (Rattus norvegicus)9068941 RGDPMID:3079759 and REF_RGD_ID:1641816

Cellular Component

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-Ratcytosol is_active_inIEAUniProtKB:Q8VEE0 and ensembl:ENSMUSP00000027157150520179 EnsemblGO_REF:0000107

Molecular Function
1 to 12 of 12 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-Ratcarbohydrate binding  ISORpe (Rattus norvegicus)9068941 RGDPMID:2843500 and REF_RGD_ID:1599574
RpeNaked Mole-RatD-ribulose-phosphate 3-epimerase activity  ISORpe (Rattus norvegicus)9068941 RGDPMID:2843500 more ...
RpeNaked Mole-RatD-ribulose-phosphate 3-epimerase activity enablesIEAEC:5.1.3.1150520179 UniProtGO_REF:0000003
RpeNaked Mole-RatD-ribulose-phosphate 3-epimerase activity enablesIEAInterPro:IPR026019150520179 InterProGO_REF:0000002
RpeNaked Mole-RatD-ribulose-phosphate 3-epimerase activity enablesIEAUniProtKB:Q8VEE0 and ensembl:ENSMUSP00000027157150520179 EnsemblGO_REF:0000107
RpeNaked Mole-Ratidentical protein binding enablesISOUniProtKB:Q96AT99068941 PMID:16189514 more ...IntActPMID:16189514 more ...
RpeNaked Mole-Ratisomerase activity enablesIEAUniProtKB-KW:KW-0413150520179 UniProtGO_REF:0000043
RpeNaked Mole-Ratmetal ion binding enablesIEAUniProtKB-KW:KW-0479150520179 UniProtGO_REF:0000043
RpeNaked Mole-Ratmonosaccharide binding  ISORpe (Rattus norvegicus)9068941 RGDPMID:3079759 and REF_RGD_ID:1641816
RpeNaked Mole-Ratprotein binding enablesISOUniProtKB:Q9H8W49068941 PMID:32296183IntActPMID:32296183
RpeNaked Mole-Ratprotein homodimerization activity enablesISOUniProtKB:Q96AT99068941 PMID:20923965UniProtPMID:20923965
RpeNaked Mole-Ratracemase and epimerase activity, acting on carbohydrates and derivatives enablesIEAInterPro:IPR000056150520179 InterProGO_REF:0000002
1 to 12 of 12 rows

RGD Manual Annotations


  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-Ratpentose phosphate pathway   ISORpe (Rattus norvegicus)9068941 RGDPMID:2843500 and REF_RGD_ID:1599574
RpeNaked Mole-Ratpentose phosphate pathway - non-oxidative phase  ISORpe (Rattus norvegicus)9068941 RGDPMID:12721358 and REF_RGD_ID:1641814

Imported Annotations - SMPDB

Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
RpeNaked Mole-Ratpentose phosphate pathway   ISORPE (Homo sapiens)9068941 SMPDBSMP:00031
RpeNaked Mole-Ratribose 5-phosphate isomerase deficiency pathway  ISORPE (Homo sapiens)9068941 SMPDBSMP:00519
RpeNaked Mole-Rattransaldolase deficiency pathway  ISORPE (Homo sapiens)9068941 SMPDBSMP:00520
PMID:21993625   PMID:22301074   PMID:30032202  



Rpe
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247656,205,972 - 6,222,636 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247656,188,964 - 6,222,580 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2
RPE
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382210,002,638 - 210,022,260 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2210,002,565 - 210,022,260 (+)EnsemblGRCh38hg38GRCh38
GRCh372210,867,362 - 210,886,984 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362210,575,597 - 210,594,536 (+)NCBINCBI36Build 36hg18NCBI36
Build 342210,692,886 - 210,711,796NCBI
Celera2204,635,382 - 204,654,317 (+)NCBICelera
Cytogenetic Map2q34NCBI
HuRef2202,712,085 - 202,732,295 (+)NCBIHuRef
CHM1_12210,873,478 - 210,893,159 (+)NCBICHM1_1
T2T-CHM13v2.02210,483,346 - 210,502,965 (+)NCBIT2T-CHM13v2.0
Rpe
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39166,739,957 - 66,758,964 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl166,739,990 - 66,758,964 (+)EnsemblGRCm39 Ensembl
GRCm38166,700,797 - 66,719,805 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl166,700,831 - 66,719,805 (+)EnsemblGRCm38mm10GRCm38
MGSCv37166,747,467 - 66,766,379 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36166,634,101 - 66,653,013 (+)NCBIMGSCv36mm8
Celera167,215,120 - 67,233,622 (+)NCBICelera
Cytogenetic Map1C3NCBI
cM Map133.61NCBI
Rpe
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8975,640,867 - 75,661,009 (+)NCBIGRCr8
mRatBN7.2968,191,027 - 68,211,295 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl968,191,292 - 68,211,591 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx976,683,016 - 76,701,336 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0981,811,955 - 81,830,275 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0980,206,660 - 80,228,639 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0973,687,684 - 73,713,643 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl973,687,743 - 73,711,571 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0973,592,974 - 73,615,163 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4965,470,071 - 65,490,200 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera965,672,114 - 65,690,468 (+)NCBICelera
Cytogenetic Map9q32NCBI
Rpe
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554575,425,532 - 5,441,538 (-)NCBIChiLan1.0ChiLan1.0
RPE
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213112,625,893 - 112,645,620 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B112,640,872 - 112,661,872 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B97,260,348 - 97,282,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B215,663,592 - 215,685,654 (+)NCBIpanpan1.1PanPan1.1panPan2
RPE
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13717,866,729 - 17,882,702 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3718,747,197 - 18,762,940 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03717,804,510 - 17,820,257 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3717,804,539 - 17,827,714 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13717,757,437 - 17,773,149 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03717,719,697 - 17,735,453 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03717,734,148 - 17,753,357 (+)NCBIUU_Cfam_GSD_1.0
Rpe
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303166,331,725 - 166,407,427 (+)NCBIHiC_Itri_2
SpeTri2.0NW_004936845188,414 - 264,070 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPE
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.115112,723,318 - 112,748,337 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215124,443,417 - 124,460,265 (+)NCBISscrofa10.2Sscrofa10.2susScr3
RPE
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11095,702,525 - 95,721,807 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666040103,634,078 - 103,652,793 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

.






Ensembl Acc Id: ENSHGLT00000011461   ⟹   ENSHGLP00000011334
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247656,205,972 - 6,222,636 (-)Ensembl
RefSeq Acc Id: XM_004851118   ⟹   XP_004851175
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,191,683 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_004851119   ⟹   XP_004851176
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,188,964 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_004851120   ⟹   XP_004851177
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,204,456 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_013074487   ⟹   XP_012929941
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,204,456 - 6,222,572 (-)NCBI
RefSeq Acc Id: XM_021263501   ⟹   XP_021119160
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,189,490 - 6,222,579 (-)NCBI
RefSeq Acc Id: XM_021263502   ⟹   XP_021119161
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,191,683 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_021263503   ⟹   XP_021119162
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,188,964 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_021263505   ⟹   XP_021119164
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,191,683 - 6,222,580 (-)NCBI
RefSeq Acc Id: XM_021263506   ⟹   XP_021119165
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247656,188,964 - 6,222,580 (-)NCBI
1 to 5 of 10 rows
1 to 5 of 10 rows
RefSeq Acc Id: XP_004851176   ⟸   XM_004851119
- Peptide Label: isoform X3
- UniProtKB: A0AAX6PGM8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119165   ⟸   XM_021263506
- Peptide Label: isoform X5
- UniProtKB: A0AAX6TDT5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119162   ⟸   XM_021263503
- Peptide Label: isoform X2
- UniProtKB: A0AAX6PFN4 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119160   ⟸   XM_021263501
- Peptide Label: isoform X1
- UniProtKB: G5AL22 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021119164   ⟸   XM_021263505
- Peptide Label: isoform X5
- UniProtKB: A0AAX6TDT5 (UniProtKB/TrEMBL)



1 to 21 of 21 rows
Database
Acc Id
Source(s)
Ensembl Genes ENSHGLG00000008127 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSHGLT00000011461 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 3.20.20.70 UniProtKB/TrEMBL
InterPro Aldolase_TIM UniProtKB/TrEMBL
  Ribul_P_3_epim UniProtKB/TrEMBL
  Ribul_P_3_epim-like UniProtKB/TrEMBL
  RibuloseP-bd_barrel UniProtKB/TrEMBL
KEGG Report hgl:101698495 UniProtKB/TrEMBL
NCBI Gene Rpe ENTREZGENE
PANTHER PTHR11749 UniProtKB/TrEMBL
Pfam Ribul_P_3_epim UniProtKB/TrEMBL
PIRSF RPE UniProtKB/TrEMBL
PROSITE RIBUL_P_3_EPIMER_1 UniProtKB/TrEMBL
  RIBUL_P_3_EPIMER_2 UniProtKB/TrEMBL
Superfamily-SCOP SSF51366 UniProtKB/TrEMBL
UniProt A0AAX6PFN4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PGM8 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6PGT4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6QYZ4 ENTREZGENE, UniProtKB/TrEMBL
  A0AAX6TDT5 ENTREZGENE, UniProtKB/TrEMBL
  G5AL22 ENTREZGENE, UniProtKB/TrEMBL
1 to 21 of 21 rows