Advanced Search (OLGA)

Gene: SLC4A1 (solute carrier family 4 member 1) Sus scrofa

Analyze

Symbol:

SLC4A1

Name:

solute carrier family 4 member 1

RGD ID:

13892510

Description:

ENCODES a protein that exhibits actin binding (ortholog); enzyme binding (ortholog); protein-containing complex binding (ortholog); INVOLVED IN bicarbonate transport (ortholog); blood coagulation (ortholog); circadian rhythm (ortholog); ASSOCIATED WITH acanthocytosis (ortholog); Alkalosis (ortholog); autoimmune hemolytic anemia (ortholog); FOUND IN basolateral plasma membrane (ortholog); cell surface (ortholog); intercalated disc (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

band 3 anion transport protein; solute carrier family 4 member 1 (Diego blood group); solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	18,957,807 - 18,974,208 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	18,957,813 - 18,975,266 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	19,180,392 - 19,196,592 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

acanthocytosis (ISO)

Alkalosis (ISO)

autoimmune hemolytic anemia (ISO)

autosomal recessive distal renal tubular acidosis 3 with or without sensorineural hearing loss (ISO)

Cardiomegaly (ISO)

congenital hemolytic anemia (ISO)

Distal Renal Tubular Acidosis (ISO)

Distal Renal Tubular Acidosis 1 (ISO)

Distal Renal Tubular Acidosis 4 with Hemolytic Anemia (ISO)

Distal Renal Tubular Acidosis, with Normal Red Cell Morphology (ISO)

genetic disease (ISO)

glucosephosphate dehydrogenase deficiency (ISO)

hematopoietic system disease (ISO)

hemolytic anemia (ISO)

hereditary elliptocytosis (ISO)

hereditary spherocytosis (ISO)

hereditary spherocytosis type 4 (ISO)

iron deficiency anemia (ISO)

malaria (ISO)

Malarial Anemia (ISO)

metabolic acidosis (ISO)

Ovalocytosis, Malaysian-Melanesian-Filipino Type (ISO)

Potassium Deficiency (ISO)

Pseudohyperkalemia, Familial, 2, due to Red Cell Leak (ISO)

renal tubular acidosis (ISO)

thrombocytopenia (ISO)

Vaso-occlusive Crisis (ISO)

Vitamin E Deficiency (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

bicarbonate transport (IBA,IEA,ISO)

blood coagulation (ISO)

chloride transmembrane transport (IEA)

chloride transport (IEA)

circadian rhythm (ISO)

erythrocyte development (ISO)

monoatomic anion transmembrane transport (IEA)

monoatomic anion transport (IEA)

monoatomic ion transport (IEA)

negative regulation of glycolytic process through fructose-6-phosphate (ISO)

negative regulation of oxidoreductase activity (ISO)

negative regulation of urine volume (ISO)

pH elevation (ISO)

plasma membrane phospholipid scrambling (ISO)

positive regulation of T cell proliferation (ISO)

protein localization to plasma membrane (ISO)

regulation of intracellular pH (IBA)

response to acidic pH (ISO)

response to activity (ISO)

response to alkaline pH (ISO)

response to arsenic-containing substance (ISO)

response to carbon dioxide (ISO)

response to hydrogen peroxide (ISO)

response to nutrient levels (ISO)

transmembrane transport (IBA,IEA)

Cellular Component

ankyrin-1 complex (IEA)

basolateral plasma membrane (IBA,IEA,ISO)

cell surface (ISO)

cortical cytoskeleton (IEA)

cytoplasm (IEA)

cytoplasmic side of plasma membrane (IEA)

intercalated disc (ISO)

membrane (IEA)

plasma membrane (IBA,IEA)

Z disc (ISO)

Molecular Function

actin binding (ISO)

ankyrin binding (IEA)

antiporter activity (IEA)

bicarbonate transmembrane transporter activity (IBA,IEA)

chloride transmembrane transporter activity (IEA)

chloride:bicarbonate antiporter activity (IEA)

cytoskeletal protein binding (IEA)

enzyme binding (ISO)

hemoglobin binding (IEA)

monoatomic anion transmembrane transporter activity (IEA)

protein binding (ISO)

protein homodimerization activity (IEA)

protein-containing complex binding (ISO)

solute:inorganic anion antiporter activity (IEA)

symporter activity (IEA)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

SLC4A1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	18,957,807 - 18,974,208 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	18,957,813 - 18,975,266 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	19,180,392 - 19,196,592 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SLC4A1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	44,248,390 - 44,268,135 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	44,248,390 - 44,268,141 (-)	Ensembl			hg38	GRCh38
GRCh37	17	42,325,758 - 42,345,503 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	39,682,566 - 39,700,993 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	39,682,565 - 39,700,993	NCBI
Celera	17	39,034,465 - 39,054,210 (-)	NCBI		Celera
Cytogenetic Map	17	q21.31	NCBI
HuRef	17	38,089,106 - 38,108,850 (-)	NCBI		HuRef
CHM1_1	17	42,561,259 - 42,581,020 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	45,101,499 - 45,121,240 (-)	NCBI		T2T-CHM13v2.0

Slc4a1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	102,239,646 - 102,256,107 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	102,239,650 - 102,257,029 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	102,348,820 - 102,365,281 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	102,348,824 - 102,366,203 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	102,210,134 - 102,226,595 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	102,164,917 - 102,181,205 (-)	NCBI		MGSCv36	mm8
Celera	11	114,058,195 - 114,074,658 (-)	NCBI		Celera
Cytogenetic Map	11	D	NCBI
cM Map	11	66.29	NCBI

Slc4a1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	87,807,010 - 87,823,274 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	87,807,013 - 87,823,258 (-)	Ensembl				GRCr8
mRatBN7.2	10	87,306,865 - 87,323,132 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	87,306,872 - 87,323,117 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	92,337,653 - 92,353,898 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	91,809,157 - 91,825,395 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	87,202,487 - 87,218,725 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	10	90,947,935 - 90,964,111 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	10	91,679,120 - 91,695,300 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	10	93,124,203 - 93,140,383 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	10	93,232,114 - 93,248,294 (-)	NCBI		F344_StmMcwi
Rnor_6.0	10	90,296,144 - 90,312,401 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	90,296,141 - 90,312,386 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	90,084,734 - 90,101,181 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	91,454,824 - 91,471,072 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	86,018,849 - 86,032,669 (-)	NCBI		Celera
RGSC_v3.1	10	91,470,679 - 91,479,502 (-)	NCBI
Cytogenetic Map	10	q32.1	NCBI

Slc4a1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	17,315,024 - 17,328,103 (-)	Ensembl
ChiLan1.0	NW_004955451	17,318,600 - 17,330,943 (-)	NCBI	ChiLan1.0	ChiLan1.0

SLC4A1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	20,646,600 - 20,663,305 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	22,612,307 - 22,627,663 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	13,131,851 - 13,150,872 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	13,302,796 - 13,317,312 (+)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	13,302,796 - 13,317,312 (+)	Ensembl			panPan2	panpan1.1

SLC4A1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	19,142,884 - 19,159,449 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	19,146,480 - 19,157,915 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	18,535,326 - 18,546,756 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	19,836,393 - 19,852,954 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	19,839,985 - 19,851,420 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	18,693,717 - 18,705,143 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	18,877,006 - 18,888,427 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	19,021,401 - 19,032,836 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Slc4a1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	18,460,919 - 18,477,383 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936541	718,577 - 729,876 (-)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936541	718,577 - 727,420 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SLC4A1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	62,126,370 - 62,146,192 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	62,131,709 - 62,146,182 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666077	32,895,386 - 32,915,473 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Slc4a1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	743,646 - 752,103 (+)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624795	739,821 - 752,773 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Slc4a1
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	61,646,785 - 61,658,882 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in SLC4A1
521 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
1	2	7	2	5	7	9	7	3	4	1

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_005668756	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_021066870	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AEMK02000080	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU468984	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01053580	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000035092 ⟹ ENSSSCP00000030398

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	12	18,957,807 - 18,974,208 (+)	Ensembl

RefSeq Acc Id:

XM_005668756 ⟹ XP_005668813

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	18,957,813 - 18,975,266 (+)	NCBI

Sequence:

show sequence

GGAACTGTCCCCGGGGCGCACAAGCAGGAACCCGGCGCTGTTAGAGCGGGCGTGAGCTCAGCTG
GTCACAGAGGCCACCGGCGGCTGCAGGAGGTCACCGAGGGACCCCAAAGCTCTCGAGCAGGGAC
CCGCAGTGCGGGTTATGCTGGGGGCTCAGATCACTGCAGACAACTGAACAGTCAGCACAGCGCC
ATGGGGGACTTCCAGGATAATGAAGAGAGGCTGGAGGAGAATTTAGGGGTGCAGGACTATGAAG
ACCAAGCTCCCCCCACGATCAGGGAGGAGGACCCAGAAGCTCAGCTCACTGAGCCAACGGCCAC
CGACTACCACACTGCATCGCGGCACCTAGACACCCATAAGTTACCTGAGCAGCTGCAGATTGGT
GTGGAGCTGCGGGAACTGGTGATGGATGAAAAGAACCAGGAGATGCAGTGGATGGAGAGAGCGC
GGTGGGTGCGGCTGGAGGAGAACCTGGGGAAGGATGGGACCTGGGGCCGCCCACACCTGTCTTA
CCTCACCTTCTGGAACCTGTTAGAGCTGCAGAAAGCCTTCACCAAGGGTACTGTCCTCCTGGAC
CTGCCAGAGAAATCCCTGCCCGGGGTGGTCGTGCAGCTGCTGGACAGGTTTATCTTCGAGGGGC
AGATCCGGCCTGAACACCGAGAGCCCCTGCTCCGGACCCTGCTGCTCAAACACAGCCACGCCAG
AGATATAGAGGTCCTGGGGGAGATGAAGCCTGCGCTCTTGACACCTGCGGGCCCTTCGCAGCCT
CTGCTCCCACAGCAGCCTTCGCTGGAAGTAGAGCTCTTTTGTGAACAGGGAGAGGGGAGCATGG
AAGGCCACTCATCTGAAATCCTGGGGAAGAGCCCTGAGAACCTGGACACGCTGGTGCTGGTGGG
CCAAGTCTCCTTCCTGGAGCGGCCGGTGCTGGGCTTCGTGCGGCTAAAGGAGCCCATGGAGATG
GAGCAGGAGACGGAGCAGGAGATGGAGCAGAAGCCAGAGGAGACAGAGGCGCTGGCAGTGCCTC
TGCGCTTCCTCATGGTGCTGCTGGGACCGGAGGACCCTCATATTGACTACAATCAGCTGGGCCG
GGCTGCTGCCACCCTCCTGTCAGAGAAGGTGTTCCACGCTGAGGCACGCGTGGCTCAGAGCAAG
GAGGAGCTGGTACATTCTCTGGGGGGCTTCCTAGACTGCAGTCTGGTGCTGCCGCCCTCAGACA
CCTACTCGGAGAAGGACCTGCTCAGCCTGATACCTGTGCAGAGGGCACTGCTGAAAAGACGCAA
ACTCCCCAGTCCTGCCAAGCAGGAACCCAGCTTCTACATGGGCCTAGACGTGGATGGGGGCATA
GAAGACAAAGACGACCCTCTGAGGAGGACGGGCAAGCTTTTCGGGGGCCTGGTGCGTGACATCC
GGCGCCGCTACCCGCGCTACTTGAGTGACATCACAGACGCCTTGAGTCCCCAGGTCCTATCTGC
CATCATCTTCATCTACTTTGCCGCCCTGTCGCCTGCCATCACCTTCGGCGGCCTCCTGGGAGAA
AAGACCCAGAACCTGATGGGCGTGTCGGAGCTGCTCATCTCTACGTCAGCGCAGGGCATCGTCT
TCTCCCTGCTGGGGGCTCAGCCCCTGCTCGTGGTGGGCTTCTCAGGACCCCTGCTCGTGTTTGA
GGAAGCCTTCTACTCGTTCTGCCAGAGTAACGGCCTGGAGTACATCGTGGGCCGTGTGTGGATT
GGCTACTGGCTCATCTTTCTGGTGGTGCTGGTGGTGGCCTTTGAGGGCAGCTTCCTGGTCCGCT
TCATCTCTCGCTACACCCAAGAGATCTTCTCCTTCCTCATCTCCCTCATCTTCATCTTCGAGAC
CTTCAAAAAGCTGTACAAGATCTTCGAGGAGCACCCACTGAAGAAGGATTATTCTGCGGCAGGG
CCGTCCCAACCCAACACAGCCCTCCTCTCTCTTGTGCTCATGGCGGGCACCTTCTTCTTAGCCA
TGCTGCTGCGCAAGTTCAAGAACAGCTCCTACTTCCCTGGCAAGCTGCGACGGGTCATCGGGGA
CTTTGGGGTTCCCATTTCCATCCTGATCATGGTCTTGGTGGATGTCTTCATTGAGGAGACCTAC
ACACAGAAACTCAGCGTGCCTTCAGGCTTCACTGTATCCAACTCCTCTGCCCGAGGCTGGCTCA
TCCACCCGCTGGGCCAGGGTGGCTCATTTCCCATCTGGATGATGTTTGCGTCCGTCCTGCCTGC
CATGCTGGTCTTCATCCTCATCTTCCTAGAGACCCAGATCACCACGCTGATCGTCAGCAAACCA
GAGCGCAAGATGGTCAAGGGCTCCGGCTTCCACCTGGACCTGCTGCTGATCATGGGCATGGGTG
GGGTGGCCGCCATCTTTGGGTTGCCCTGGCTCAGTGCCACCACCGTGCGTTCTGTCACCCACGC
CAATGCCCTCACGGTCATGAGCAAGTCCAGCATCCCAGGAGCTGCTTCCCAGATTCAGGAAGTC
AAGGAACAGCGGATCAGCGGGCTCCTGGTCGCTGTGCTCGTGGGCCTGTCCATCCTCATGGGGC
CCATCCTGTCCCACATCCCCCTGGCTGTGCTGTTTGGCATCTTCCTCTACATGGGGGTCACGTC
ACTCAGTGGCATCCAGCTCTTTGACCGCATCTTGCTTCTGTTCAAGCCGTCCAAGTACCACCCG
GATATACCCTATGCCAAGCGGGTGAGAACCTGGCGCATGCACCTGTACACGCTCACCCAGATCA
TCTGCCTCGTGGTGCTGTGGACGGTGAAGTTCTTCCCATCCACCTCGCTGGCCCTGCCCTTCGT
CCTCATCCTCACGGTGCCCCTCCGCCTCTTCCTGCTGCCACTCATCTTCAGGAAACTGGAGCTC
CAATGTCTGGATGCTGATGATGCGAAGCCCAACTTAGACGAGGAGCACGGTCGGGATGAATATG
ACGAGGTGCACATGCCTGTGTGAGGGGGGGCCCGGGCCCCGGCGCCCCCTCCACCGTTCCACGG
GCCCACTCTCCCAGGAAAAGCAGAGGCTCATGGGCACCTCCTGGACTCCCAGGTCCCTCCGGGG
GAAGCAGCTGAGGTCCGGGGGCCATGGGTTAGGGGGAAGGAAGGGGTGTCTAAGAAACCTTCCG
TGAAGGGTAGGCTGGCTTTTCTGGCAGGAAATGGCCAGTGGGGTCCACAGCAGGGGATTTACCG
TGCAGTCCCTTCTGGGGCCACACTGCCACTTGGGGGGTCCCACGCCAGAAGACCTAGATCTGAG
CCCTCATGGCACAGACAGGAGCAGTGATGGGGGTGGAGGGAGGGCGCTAGGGGAAGGGTGGGTA
TTCAAATTCCTATTTGCTGTGTGACCTTGGGCAAGTCCTTGGATCTCTCCAGCCTCTGCTTCCT
CATCTGTAAAATGGGTATATCAATAATCACATACCCACATTACAGGATGGTTTCTGAGGACCAA
AGATAAATGTGAGGAAAGGGCTTTGGGAGTTCCTGTCATGGCAGAGTGGTTAACGACTCCGACT
AAGAACCATGAGGTTTGGGGTTCGATCCCTGGCCTCGCTCAGTGGGTTAAGGATCCGGCGTTGC
CATGAGCTGTGGTGTAGGTTGCAGATGCGGCTTGGATCCTGCGTTGCTGTGGCTCTGGCATAGG
CCGGTGGCTACAGCTCCAATTGGACCGCTAGCCTGGGAACCTCCATGTGCCGTGGGAGCGGCCT
TAGAAAAGGCAAAAAAGACAAAAGAAAAGAAAAGAAAAGAAAAGGGCTTTGTAAAATCTAAAAA
GCTATTACACAATAGTCTTCGATTCTTCCTCAAGCCTGCCCAAGGCCATGTAGCTCCTGAGCCA
CATGGCTGGGATTTGAACTCTAAAAGTCTACTTCAGTCACCCACCTTTCCACACTTAGAGATGT
GCCTGCTGGCTCCCCCGCCACCTCTCTGCTCCCACTGGGGACCCTCTTCTCTGGGCCAGAGGGA
GGTGTCCGGGTGAGGGCAAGGTGCAGGCAAGGTGCAGGCGAGGACAGAATCAGGGCTGGGACTC
AGGACTCCTAAATGCTTGCCCCCCTTCCCCACGCTCTCATTCATCCCACAAACACTTACCAAAG
TCCCTGGACCCCATGGGCACAGAGGTGCCTGAGACAAGACCTTGCCCTGGGGTTGGGGTGGGGC
AATGTACAGTCTGTTCTGAATTTGGGTGGGGGGTGGGGGGAAGGTGAGAATATAGGAAGAAGAT
GGGGAGGGGAGGGAGGTTTGTAATTTATACCTTGTGTATTCTCAGAGCTTTTGTTGTACTTCAG
CACATGCGCGCGCGTGCATACGCACACACACACACACACACACACACTTAGAGACCCACTGTCC
CCAGCCCCACCTGAAACAAATCTTGGAGAGATCCTAGATTCAAACTCTTGGGGTTAGAGACAGT
TAGGGTCTGCAGAATATGGATAAAATCTATATATATATATATATATATATATATATATATATAT
TTTTTTTACAAAAAGAAAGTATAAAAAGAGTGGAAAGAACTGGAAGTGGCGAGAGATGGTTAAC
ACTGAAAATCAGGGTGTTACAGAGAAGCAAGGAGGTTGAGAGAGGGCTGACGGCTACCTCCCAC
CCCTTTGCTGTTTCATGCCCCATCTGTAAACTGGGACCAGTAAGGGTACCTACTTCATAGGGTT
GTTATAAGGCTTAAAGGAGACGTGCCTGCAAAGAGATGGCTCAGCACAGAGCCTGGTCTCAGAC
CTCCGCAGAAGAGCTCAATAAAGTTAGCTGCTGGTATTGTGA

hide sequence

RefSeq Acc Id:

XM_021066870 ⟹ XP_020922529

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	12	18,961,977 - 18,974,196 (+)	NCBI

Sequence:

show sequence

GTGAGGGCTGGGGGTGCGGGGGCAATATAAGAGCCCACCCCACCCGGGCACCCGGAGCTCCCCG
TGGAGGCAGCAAGAAGCTACCTGGCTGGTGGGATTATCTAGGCAGCTCAGCTCACTGAGCCAAC
GGCCACCGACTACCACACTGCATCGCGGCACCTAGACACCCATAAGTTACCTGAGCAGCTGCAG
ATTGGTGTGGAGCTGCGGGAACTGGTGATGGATGAAAAGAACCAGGAGATGCAGTGGATGGAGA
GAGCGCGGTGGGTGCGGCTGGAGGAGAACCTGGGGAAGGATGGGACCTGGGGCCGCCCACACCT
GTCTTACCTCACCTTCTGGAACCTGTTAGAGCTGCAGAAAGCCTTCACCAAGGGTACTGTCCTC
CTGGACCTGCCAGAGAAATCCCTGCCCGGGGTGGTCGTGCAGCTGCTGGACAGGTTTATCTTCG
AGGGGCAGATCCGGCCTGAACACCGAGAGCCCCTGCTCCGGACCCTGCTGCTCAAACACAGCCA
CGCCAGAGATATAGAGGTCCTGGGGGAGATGAAGCCTGCGCTCTTGACACCTGCGGGCCCTTCG
CAGCCTCTGCTCCCACAGCAGCCTTCGCTGGAAGTAGAGCTCTTTTGTGAACAGGGAGAGGGGA
GCATGGAAGGCCACTCATCTGAAATCCTGGGGAAGAGCCCTGAGAACCTGGACACGCTGGTGCT
GGTGGGCCAAGTCTCCTTCCTGGAGCGGCCGGTGCTGGGCTTCGTGCGGCTAAAGGAGCCCATG
GAGATGGAGCAGGAGACGGAGCAGGAGATGGAGCAGAAGCCAGAGGAGACAGAGGCGCTGGCAG
TGCCTCTGCGCTTCCTCATGGTGCTGCTGGGACCGGAGGACCCTCATATTGACTACAATCAGCT
GGGCCGGGCTGCTGCCACCCTCCTGTCAGAGAAGGTGTTCCACGCTGAGGCACGCGTGGCTCAG
AGCAAGGAGGAGCTGGTACATTCTCTGGGGGGCTTCCTAGACTGCAGTCTGGTGCTGCCGCCCT
CAGACACCTACTCGGAGAAGGACCTGCTCAGCCTGATACCTGTGCAGAGGGCACTGCTGAAAAG
ACGCAAACTCCCCAGTCCTGCCAAGCAGGAACCCAGCTTCTACATGGGCCTAGACGTGGATGGG
GGCATAGAAGACAAAGACGACCCTCTGAGGAGGACGGGCAAGCTTTTCGGGGGCCTGGTGCGTG
ACATCCGGCGCCGCTACCCGCGCTACTTGAGTGACATCACAGACGCCTTGAGTCCCCAGGTCCT
ATCTGCCATCATCTTCATCTACTTTGCCGCCCTGTCGCCTGCCATCACCTTCGGCGGCCTCCTG
GGAGAAAAGACCCAGAACCTGATGGGCGTGTCGGAGCTGCTCATCTCTACGTCAGCGCAGGGCA
TCGTCTTCTCCCTGCTGGGGGCTCAGCCCCTGCTCGTGGTGGGCTTCTCAGGACCCCTGCTCGT
GTTTGAGGAAGCCTTCTACTCGTTCTGCCAGAGTAACGGCCTGGAGTACATCGTGGGCCGTGTG
TGGATTGGCTACTGGCTCATCTTTCTGGTGGTGCTGGTGGTGGCCTTTGAGGGCAGCTTCCTGG
TCCGCTTCATCTCTCGCTACACCCAAGAGATCTTCTCCTTCCTCATCTCCCTCATCTTCATCTT
CGAGACCTTCAAAAAGCTGTACAAGATCTTCGAGGAGCACCCACTGAAGAAGGATTATTCTGCG
GCAGGGCCGTCCCAACCCAACACAGCCCTCCTCTCTCTTGTGCTCATGGCGGGCACCTTCTTCT
TAGCCATGCTGCTGCGCAAGTTCAAGAACAGCTCCTACTTCCCTGGCAAGCTGCGACGGGTCAT
CGGGGACTTTGGGGTTCCCATTTCCATCCTGATCATGGTCTTGGTGGATGTCTTCATTGAGGAG
ACCTACACACAGAAACTCAGCGTGCCTTCAGGCTTCACTGTATCCAACTCCTCTGCCCGAGGCT
GGCTCATCCACCCGCTGGGCCAGGGTGGCTCATTTCCCATCTGGATGATGTTTGCGTCCGTCCT
GCCTGCCATGCTGGTCTTCATCCTCATCTTCCTAGAGACCCAGATCACCACGCTGATCGTCAGC
AAACCAGAGCGCAAGATGGTCAAGGGCTCCGGCTTCCACCTGGACCTGCTGCTGATCATGGGCA
TGGGTGGGGTGGCCGCCATCTTTGGGTTGCCCTGGCTCAGTGCCACCACCGTGCGTTCTGTCAC
CCACGCCAATGCCCTCACGGTCATGAGCAAGTCCAGCATCCCAGGAGCTGCTTCCCAGATTCAG
GAAGTCAAGGAACAGCGGATCAGCGGGCTCCTGGTCGCTGTGCTCGTGGGCCTGTCCATCCTCA
TGGGGCCCATCCTGTCCCACATCCCCCTGGCTGTGCTGTTTGGCATCTTCCTCTACATGGGGGT
CACGTCACTCAGTGGCATCCAGCTCTTTGACCGCATCTTGCTTCTGTTCAAGCCGTCCAAGTAC
CACCCGGATATACCCTATGCCAAGCGGGTGAGAACCTGGCGCATGCACCTGTACACGCTCACCC
AGATCATCTGCCTCGTGGTGCTGTGGACGGTGAAGTTCTTCCCATCCACCTCGCTGGCCCTGCC
CTTCGTCCTCATCCTCACGGTGCCCCTCCGCCTCTTCCTGCTGCCACTCATCTTCAGGAAACTG
GAGCTCCAATGTCTGGATGCTGATGATGCGAAGCCCAACTTAGACGAGGAGCACGGTCGGGATG
AATATGACGAGGTGCACATGCCTGTGTGAGGGGGGGCCCGGGCCCCGGCGCCCCCTCCACCGTT
CCACGGGCCCACTCTCCCAGGAAAAGCAGAGGCTCATGGGCACCTCCTGGACTCCCAGGTCCCT
CCGGGGGAAGCAGCTGAGGTCCGGGGGCCATGGGTTAGGGGGAAGGAAGGGGTGTCTAAGAAAC
CTTCCGTGAAGGGTAGGCTGGCTTTTCTGGCAGGAAATGGCCAGTGGGGTCCACAGCAGGGGAT
TTACCGTGCAGTCCCTTCTGGGGCCACACTGCCACTTGGGGGGTCCCACGCCAGAAGACCTAGA
TCTGAGCCCTCATGGCACAGACAGGAGCAGTGATGGGGGTGGAGGGAGGGCGCTAGGGGAAGGG
TGGGTATTCAAATTCCTATTTGCTGTGTGACCTTGGGCAAGTCCTTGGATCTCTCCAGCCTCTG
CTTCCTCATCTGTAAAATGGGTATATCAATAATCACATACCCACATTACAGGATGGTTTCTGAG
GACCAAAGATAAATGTGAGGAAAGGGCTTTGGGAGTTCCTGTCATGGCAGAGTGGTTAACGACT
CCGACTAAGAACCATGAGGTTTGGGGTTCGATCCCTGGCCTCGCTCAGTGGGTTAAGGATCCGG
CGTTGCCATGAGCTGTGGTGTAGGTTGCAGATGCGGCTTGGATCCTGCGTTGCTGTGGCTCTGG
CATAGGCCGGTGGCTACAGCTCCAATTGGACCGCTAGCCTGGGAACCTCCATGTGCCGTGGGAG
CG

hide sequence

Protein Sequences


Protein RefSeqs	XP_005668813	(Get FASTA)	NCBI Sequence Viewer
	XP_020922529	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000030398
	ENSSSCP00000030398.1
	ENSSSCP00015045379.1
	ENSSSCP00015045429.1
	ENSSSCP00025029646.1
	ENSSSCP00030040527.1
	ENSSSCP00035044102.1
	ENSSSCP00040025314.1
	ENSSSCP00045019934.1
	ENSSSCP00050032321.1
	ENSSSCP00055034890.1
	ENSSSCP00060046478.1
	ENSSSCP00065046290.1

RefSeq Acc Id:	XP_005668813 ⟸ XM_005668756
- Peptide Label:	isoform X1
- UniProtKB:	K7GR72 (UniProtKB/TrEMBL), A0A8D1HL68 (UniProtKB/TrEMBL), A0A8D0Q8W9 (UniProtKB/TrEMBL), A0A8D0SEJ4 (UniProtKB/TrEMBL), A0A8D1EPB8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGDFQDNEERLEENLGVQDYEDQAPPTIREEDPEAQLTEPTATDYHTASRHLDTHKLPEQLQIG VELRELVMDEKNQEMQWMERARWVRLEENLGKDGTWGRPHLSYLTFWNLLELQKAFTKGTVLLD LPEKSLPGVVVQLLDRFIFEGQIRPEHREPLLRTLLLKHSHARDIEVLGEMKPALLTPAGPSQP LLPQQPSLEVELFCEQGEGSMEGHSSEILGKSPENLDTLVLVGQVSFLERPVLGFVRLKEPMEM EQETEQEMEQKPEETEALAVPLRFLMVLLGPEDPHIDYNQLGRAAATLLSEKVFHAEARVAQSK EELVHSLGGFLDCSLVLPPSDTYSEKDLLSLIPVQRALLKRRKLPSPAKQEPSFYMGLDVDGGI EDKDDPLRRTGKLFGGLVRDIRRRYPRYLSDITDALSPQVLSAIIFIYFAALSPAITFGGLLGE KTQNLMGVSELLISTSAQGIVFSLLGAQPLLVVGFSGPLLVFEEAFYSFCQSNGLEYIVGRVWI GYWLIFLVVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIFETFKKLYKIFEEHPLKKDYSAAG PSQPNTALLSLVLMAGTFFLAMLLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDVFIEETY TQKLSVPSGFTVSNSSARGWLIHPLGQGGSFPIWMMFASVLPAMLVFILIFLETQITTLIVSKP ERKMVKGSGFHLDLLLIMGMGGVAAIFGLPWLSATTVRSVTHANALTVMSKSSIPGAASQIQEV KEQRISGLLVAVLVGLSILMGPILSHIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPSKYHP DIPYAKRVRTWRMHLYTLTQIICLVVLWTVKFFPSTSLALPFVLILTVPLRLFLLPLIFRKLEL QCLDADDAKPNLDEEHGRDEYDEVHMPV hide sequence

RefSeq Acc Id:	XP_020922529 ⟸ XM_021066870
- Peptide Label:	isoform X2
- UniProtKB:	A0A8D1EPB8 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDEKNQEMQWMERARWVRLEENLGKDGTWGRPHLSYLTFWNLLELQKAFTKGTVLLDLPEKSLP GVVVQLLDRFIFEGQIRPEHREPLLRTLLLKHSHARDIEVLGEMKPALLTPAGPSQPLLPQQPS LEVELFCEQGEGSMEGHSSEILGKSPENLDTLVLVGQVSFLERPVLGFVRLKEPMEMEQETEQE MEQKPEETEALAVPLRFLMVLLGPEDPHIDYNQLGRAAATLLSEKVFHAEARVAQSKEELVHSL GGFLDCSLVLPPSDTYSEKDLLSLIPVQRALLKRRKLPSPAKQEPSFYMGLDVDGGIEDKDDPL RRTGKLFGGLVRDIRRRYPRYLSDITDALSPQVLSAIIFIYFAALSPAITFGGLLGEKTQNLMG VSELLISTSAQGIVFSLLGAQPLLVVGFSGPLLVFEEAFYSFCQSNGLEYIVGRVWIGYWLIFL VVLVVAFEGSFLVRFISRYTQEIFSFLISLIFIFETFKKLYKIFEEHPLKKDYSAAGPSQPNTA LLSLVLMAGTFFLAMLLRKFKNSSYFPGKLRRVIGDFGVPISILIMVLVDVFIEETYTQKLSVP SGFTVSNSSARGWLIHPLGQGGSFPIWMMFASVLPAMLVFILIFLETQITTLIVSKPERKMVKG SGFHLDLLLIMGMGGVAAIFGLPWLSATTVRSVTHANALTVMSKSSIPGAASQIQEVKEQRISG LLVAVLVGLSILMGPILSHIPLAVLFGIFLYMGVTSLSGIQLFDRILLLFKPSKYHPDIPYAKR VRTWRMHLYTLTQIICLVVLWTVKFFPSTSLALPFVLILTVPLRLFLLPLIFRKLELQCLDADD AKPNLDEEHGRDEYDEVHMPV hide sequence

Ensembl Acc Id:

ENSSSCP00000030398 ⟸ ENSSSCT00000035092

Protein Domains

Band 3 cytoplasmic Bicarbonate transporter-like transmembrane

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000017358	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015079133	UniProtKB/TrEMBL
	ENSSSCG00025050415	UniProtKB/TrEMBL
	ENSSSCG00030062620	UniProtKB/TrEMBL
	ENSSSCG00035075892	UniProtKB/TrEMBL
	ENSSSCG00040044939	UniProtKB/TrEMBL
	ENSSSCG00045016931	UniProtKB/TrEMBL
	ENSSSCG00050054909	UniProtKB/TrEMBL
	ENSSSCG00055022287	UniProtKB/TrEMBL
	ENSSSCG00060076897	UniProtKB/TrEMBL
	ENSSSCG00065075653	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000035092	ENTREZGENE
	ENSSSCT00000035092.4	UniProtKB/TrEMBL
	ENSSSCT00015107392.1	UniProtKB/TrEMBL
	ENSSSCT00015107478.1	UniProtKB/TrEMBL
	ENSSSCT00025068856.1	UniProtKB/TrEMBL
	ENSSSCT00030087729.1	UniProtKB/TrEMBL
	ENSSSCT00035103188.1	UniProtKB/TrEMBL
	ENSSSCT00040060307.1	UniProtKB/TrEMBL
	ENSSSCT00045028799.1	UniProtKB/TrEMBL
	ENSSSCT00050074910.1	UniProtKB/TrEMBL
	ENSSSCT00055043812.1	UniProtKB/TrEMBL
	ENSSSCT00060105653.1	UniProtKB/TrEMBL
	ENSSSCT00065104438.1	UniProtKB/TrEMBL
Gene3D-CATH	Helical hairpin bin	UniProtKB/TrEMBL
	Mannitol-specific EII, Chain A	UniProtKB/TrEMBL
InterPro	Anion_exchange	UniProtKB/TrEMBL
	Anion_exchange_CS	UniProtKB/TrEMBL
	Band3_cytoplasmic_dom	UniProtKB/TrEMBL
	HCO3_transpt_C	UniProtKB/TrEMBL
	HCO3_transpt_euk	UniProtKB/TrEMBL
	PTrfase/Anion_transptr	UniProtKB/TrEMBL
KEGG Report	ssc:100514249	UniProtKB/TrEMBL
NCBI Gene	SLC4A1	ENTREZGENE
PANTHER	BAND 3 ANION TRANSPORT PROTEIN	UniProtKB/TrEMBL
	PTHR11453	UniProtKB/TrEMBL
Pfam	Band_3_cyto	UniProtKB/TrEMBL
	HCO3_cotransp	UniProtKB/TrEMBL
PRINTS	ANIONEXCHNGR	UniProtKB/TrEMBL
	HCO3TRNSPORT	UniProtKB/TrEMBL
PROSITE	ANION_EXCHANGER_1	UniProtKB/TrEMBL
Superfamily-SCOP	SSF55804	UniProtKB/TrEMBL
UniProt	A0A8D0Q8W9	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0QBD2_PIG	UniProtKB/TrEMBL
	A0A8D0SEJ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1CF87_PIG	UniProtKB/TrEMBL
	A0A8D1EPB8	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D1HL68	ENTREZGENE, UniProtKB/TrEMBL
	K7GR72	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:99051	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2020-03-31	SLC4A1	solute carrier family 4 member 1	SLC4A1	solute carrier family 4 member 1 (Diego blood group)	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM