Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Arhgap15 | Rat | (-)-demecolcine | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Demecolcine results in increased expression of ARHGAP15 mRNA | CTD | PMID:23649840 | Arhgap15 | Rat | 1,2-dichloroethane | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of ARHGAP15 mRNA | CTD | PMID:28960355 | Arhgap15 | Rat | 17beta-estradiol | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ARHGAP15 mRNA | CTD | PMID:32741896 | Arhgap15 | Rat | 17beta-estradiol 3-benzoate | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ARHGAP15 mRNA | CTD | PMID:32741896 | Arhgap15 | Rat | 2,3',4,4',5-Pentachlorobiphenyl | increases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:31388691 | Arhgap15 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ARHGAP15 mRNA | CTD | PMID:26377647 | Arhgap15 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ARHGAP15 mRNA | CTD | PMID:32109520 | Arhgap15 | Rat | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Arhgap15 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | ARHGAP15 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of ARHGAP15 gene | CTD | PMID:31601247 | Arhgap15 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ARHGAP15 mRNA | CTD | PMID:31881176 | Arhgap15 | Rat | aflatoxin B1 | increases methylation | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ARHGAP15 intron | CTD | PMID:30157460 | Arhgap15 | Rat | all-trans-retinoic acid | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Tretinoin results in increased expression of ARHGAP15 mRNA | CTD | PMID:33167477 | Arhgap15 | Rat | alpha-Zearalanol | increases expression | EXP | | 6480464 | Zeranol results in increased expression of ARHGAP15 mRNA | CTD | PMID:35163327 | Arhgap15 | Rat | amiodarone | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Amiodarone results in increased expression of ARHGAP15 mRNA | CTD | PMID:19774075 | Arhgap15 | Rat | atrazine | affects methylation | EXP | | 6480464 | Atrazine affects the methylation of ARHGAP15 gene | CTD | PMID:35440735 | Arhgap15 | Rat | benzo[a]pyrene | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of ARHGAP15 mRNA | CTD | PMID:21569818 | Arhgap15 | Rat | benzo[a]pyrene | increases methylation | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ARHGAP15 promoter | CTD | PMID:27901495 | Arhgap15 | Rat | benzo[a]pyrene | decreases methylation | ISO | Arhgap15 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased methylation of ARHGAP15 intron | CTD | PMID:27901495 | Arhgap15 | Rat | benzo[a]pyrene | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ARHGAP15 mRNA | CTD | PMID:20064835 | Arhgap15 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ARHGAP15 mRNA | CTD | PMID:25181051 | Arhgap15 | Rat | bisphenol A | increases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | bisphenol A results in increased expression of ARHGAP15 mRNA | CTD | PMID:38701888 | Arhgap15 | Rat | buta-1,3-diene | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | 1 and 3-butadiene results in decreased expression of ARHGAP15 mRNA | CTD | PMID:29038090 | Arhgap15 | Rat | cadmium atom | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARHGAP15 mRNA | CTD | PMID:35301059 | Arhgap15 | Rat | cadmium dichloride | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ARHGAP15 mRNA | CTD | PMID:35301059 | Arhgap15 | Rat | carbamazepine | affects expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of ARHGAP15 mRNA | CTD | PMID:25979313 | Arhgap15 | Rat | carbon nanotube | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Arhgap15 | Rat | CGP 52608 | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ARHGAP15 gene] | CTD | PMID:28238834 | Arhgap15 | Rat | chloroprene | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Chloroprene results in decreased expression of ARHGAP15 mRNA | CTD | PMID:23125180 | Arhgap15 | Rat | choline | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP15 mRNA | CTD | PMID:20938992 | Arhgap15 | Rat | cisplatin | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of ARHGAP15 mRNA | CTD | PMID:27594783 | Arhgap15 | Rat | Cuprizon | decreases expression | EXP | | 6480464 | Cuprizone results in decreased expression of ARHGAP15 mRNA | CTD | PMID:26577399 | Arhgap15 | Rat | DDT | decreases methylation | EXP | | 6480464 | DDT results in decreased methylation of ARHGAP15 gene | CTD | PMID:30207508 | Arhgap15 | Rat | dextran sulfate | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:29950665 | Arhgap15 | Rat | diethylstilbestrol | increases expression | EXP | | 6480464 | Diethylstilbestrol results in increased expression of ARHGAP15 mRNA | CTD | PMID:17005392 | Arhgap15 | Rat | dimethylarsinic acid | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of ARHGAP15 mRNA | CTD | PMID:34876320 | Arhgap15 | Rat | dorsomorphin | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Arhgap15 | Rat | ethanol | affects expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Ethanol affects the expression of ARHGAP15 mRNA | CTD | PMID:30319688 | Arhgap15 | Rat | ethanol | increases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Ethanol results in increased expression of ARHGAP15 mRNA | CTD | PMID:30319688 | Arhgap15 | Rat | ethyl methanesulfonate | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of ARHGAP15 mRNA | CTD | PMID:23649840 | Arhgap15 | Rat | folic acid | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP15 mRNA | CTD | PMID:20938992 | Arhgap15 | Rat | formaldehyde | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of ARHGAP15 mRNA | CTD | PMID:23649840 | Arhgap15 | Rat | genistein | increases methylation | EXP | | 6480464 | Genistein results in increased methylation of ARHGAP15 gene | CTD | PMID:28505145 | Arhgap15 | Rat | genistein | increases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Genistein results in increased expression of ARHGAP15 mRNA | CTD | PMID:32186404 | Arhgap15 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of ARHGAP15 mRNA | CTD | PMID:22061828 | Arhgap15 | Rat | glyphosate | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | Glyphosate results in decreased expression of ARHGAP15 mRNA | CTD | PMID:35897073 | Arhgap15 | Rat | L-methionine | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of ARHGAP15 mRNA | CTD | PMID:20938992 | Arhgap15 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of ARHGAP15 gene | CTD | PMID:35440735 | Arhgap15 | Rat | methyl methanesulfonate | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of ARHGAP15 mRNA | CTD | PMID:23649840 | Arhgap15 | Rat | methylarsonic acid | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of ARHGAP15 mRNA | CTD | PMID:34876320 | Arhgap15 | Rat | methylmercury chloride | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of ARHGAP15 mRNA | CTD | PMID:28001369 | Arhgap15 | Rat | nickel atom | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Nickel results in increased expression of ARHGAP15 mRNA | CTD | PMID:25583101 | Arhgap15 | Rat | ozone | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of ARHGAP15 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of ARHGAP15 mRNA | CTD | PMID:34911549 | Arhgap15 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of ARHGAP15 mRNA | CTD | PMID:26272509 | Arhgap15 | Rat | panobinostat | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:27188386 | Arhgap15 | Rat | panobinostat | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | panobinostat results in decreased expression of ARHGAP15 mRNA | CTD | PMID:26272509 | Arhgap15 | Rat | phenylmercury acetate | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:27188386 | Arhgap15 | Rat | pirinixic acid | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ARHGAP15 mRNA | CTD | PMID:20813756 | Arhgap15 | Rat | SB 431542 | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Arhgap15 | Rat | sodium arsenate | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of ARHGAP15 mRNA | CTD | PMID:34876320 | Arhgap15 | Rat | sodium arsenite | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of ARHGAP15 mRNA | CTD | PMID:34876320 | Arhgap15 | Rat | sodium arsenite | decreases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of ARHGAP15 mRNA | CTD | PMID:37682722 | Arhgap15 | Rat | testosterone | multiple interactions | EXP | | 6480464 | [estradiol 3-benzoate co-treated with [Testosterone co-treated with Estradiol]] results in increased expression of ARHGAP15 mRNA | CTD | PMID:32741896 | Arhgap15 | Rat | theophylline | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Theophylline results in increased expression of ARHGAP15 mRNA | CTD | PMID:18951874 | Arhgap15 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of ARHGAP15 mRNA | CTD | PMID:34492290 | Arhgap15 | Rat | titanium dioxide | increases expression | ISO | Arhgap15 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of ARHGAP15 mRNA | CTD | PMID:23557971 | Arhgap15 | Rat | titanium dioxide | multiple interactions | ISO | Arhgap15 (Mus musculus) | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:29950665 | Arhgap15 | Rat | trichostatin A | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | trichostatin A results in decreased expression of ARHGAP15 mRNA | CTD | PMID:24935251 and PMID:26272509 | Arhgap15 | Rat | trichostatin A | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:27188386 | Arhgap15 | Rat | triphenyl phosphate | affects expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of ARHGAP15 mRNA | CTD | PMID:37042841 | Arhgap15 | Rat | valproic acid | affects expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ARHGAP15 mRNA | CTD | PMID:25979313 | Arhgap15 | Rat | valproic acid | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ARHGAP15 mRNA | CTD | PMID:28001369 | Arhgap15 | Rat | valproic acid | decreases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ARHGAP15 mRNA | CTD | PMID:23179753 more ... | Arhgap15 | Rat | valproic acid | multiple interactions | ISO | ARHGAP15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of ARHGAP15 mRNA | CTD | PMID:27188386 | Arhgap15 | Rat | vinclozolin | increases methylation | EXP | | 6480464 | vinclozolin results in increased methylation of ARHGAP15 gene | CTD | PMID:31682807 | Arhgap15 | Rat | vincristine | increases expression | ISO | ARHGAP15 (Homo sapiens) | 6480464 | Vincristine results in increased expression of ARHGAP15 mRNA | CTD | PMID:23649840 | |