Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mars2 | Rat | spastic ataxia 3 | | ISO | MARS2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Mars2 | Rat | spastic ataxia 3 | | ISO | MARS2 (Homo sapiens) | 11554173 | CTD Direct Evidence: marker/mechanism | CTD | | |
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# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from GOA human gene data--August 2006 | GOA data from the GO Consortium |
3. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
4. | OMIM Disease Annotation Pipeline | OMIM Disease Annotation Pipeline |
5. | KEGG Annotation Import Pipeline | Pipeline to import KEGG annotations from KEGG into RGD |
6. | GOA pipeline | RGD automated data pipeline |
7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Mars2 (Rattus norvegicus - Norway rat) |
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MARS2 (Homo sapiens - human) |
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Mars2 (Mus musculus - house mouse) |
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Mars2 (Chinchilla lanigera - long-tailed chinchilla) |
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MARS2 (Pan paniscus - bonobo/pygmy chimpanzee) |
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MARS2 (Canis lupus familiaris - dog) |
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Mars2 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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MARS2 (Sus scrofa - pig) |
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MARS2 (Chlorocebus sabaeus - green monkey) |
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Mars2 (Heterocephalus glaber - naked mole-rat) |
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Variants in Mars2
31 total Variants |
The detailed report is available here: | Full Report | CSV | TAB | Printer | ||||
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | Full Report | CSV | TAB | Printer | Gviewer |
RH137164 |
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alimentary part of gastrointestinal system
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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6 | 6 | 41 | 46 | 42 | 30 | 6 | 30 | 6 | 80 | 24 | 29 | 20 | 27 | 12 |
RefSeq Transcripts | XM_001066991 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_003750699 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_003750701 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039084841 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_039084842 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC103419 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
CH473965 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000009 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000070844 ⟹ ENSRNOP00000067312 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000075508 ⟹ ENSRNOP00000067873 | ||||||||
Type: | CODING | ||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000114346 ⟹ ENSRNOP00000088692 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_003750699 ⟹ XP_003750747 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_039084841 ⟹ XP_038940769 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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RefSeq Acc Id: | XM_039084842 ⟹ XP_038940770 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Protein RefSeqs | XP_003750747 | (Get FASTA) | NCBI Sequence Viewer |
XP_038940769 | (Get FASTA) | NCBI Sequence Viewer | |
XP_038940770 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | EDL99042 | (Get FASTA) | NCBI Sequence Viewer |
Ensembl Protein | ENSRNOP00000088692.1 |
Ensembl Acc Id: | ENSRNOP00000067312 ⟸ ENSRNOT00000070844 |
Ensembl Acc Id: | ENSRNOP00000067873 ⟸ ENSRNOT00000075508 |
RefSeq Acc Id: | XP_038940769 ⟸ XM_039084841 |
- Peptide Label: | isoform X2 |
RefSeq Acc Id: | XP_038940770 ⟸ XM_039084842 |
- Peptide Label: | isoform X3 |
RefSeq Acc Id: | XP_003750747 ⟸ XM_003750699 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6IP18 (UniProtKB/TrEMBL), D4A9V7 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000088692 ⟸ ENSRNOT00000114346 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-D4A9V7-F1-model_v2 | AlphaFold | D4A9V7 | 1-586 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
Database | Acc Id | Source(s) |
AGR Gene | RGD:1311527 | AgrOrtholog |
Ensembl Genes | ENSRNOG00000048668 | Ensembl |
ENSRNOG00000050002 | Ensembl | |
ENSRNOG00000065339 | Ensembl, UniProtKB/TrEMBL | |
Ensembl Transcript | ENSRNOT00000114346.1 | UniProtKB/TrEMBL |
Gene3D-CATH | 2.170.220.10 | UniProtKB/TrEMBL |
3.40.50.620 | UniProtKB/TrEMBL | |
InterPro | Anticodon_Met | UniProtKB/TrEMBL |
Met-tRNA_synth | UniProtKB/TrEMBL | |
Met-tRNA_synth_2 | UniProtKB/TrEMBL | |
Methionyl/Leucyl_tRNA_Synth | UniProtKB/TrEMBL | |
MetRS_core | UniProtKB/TrEMBL | |
Rossmann-like_a/b/a_fold | UniProtKB/TrEMBL | |
tRNAsynth_1a_anticodon-bd | UniProtKB/TrEMBL | |
KEGG Report | rno:100911305 | UniProtKB/TrEMBL |
NCBI Gene | Mars2 | ENTREZGENE |
PANTHER | METHIONINE--TRNA LIGASE, MITOCHONDRIAL | UniProtKB/TrEMBL |
PTHR43326 | UniProtKB/TrEMBL | |
Pfam | Anticodon_3 | UniProtKB/TrEMBL |
tRNA-synt_1g | UniProtKB/TrEMBL | |
PhenoGen | Mars2 | PhenoGen |
PRINTS | TRNASYNTHMET | UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000048668 | RatGTEx |
ENSRNOG00000050002 | RatGTEx | |
ENSRNOG00000065339 | RatGTEx | |
Superfamily-SCOP | Nucleotidylyl transferase | UniProtKB/TrEMBL |
tRNAsyn_1a_bind | UniProtKB/TrEMBL | |
UniProt | A6IP18 | ENTREZGENE, UniProtKB/TrEMBL |
D4A9V7 | ENTREZGENE, UniProtKB/TrEMBL |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2021-03-09 | Mars2 | methionyl-tRNA synthetase 2, mitochondrial | LOC100911305 | methionine--tRNA ligase, mitochondrial-like | Data merged from RGD:6494075 | 737654 | PROVISIONAL |
2012-07-05 | LOC100911305 | methionine--tRNA ligase, mitochondrial-like | Symbol and Name status set to provisional | 70820 | PROVISIONAL | ||
2008-10-24 | Mars2 | methionyl-tRNA synthetase 2, mitochondrial | Mars2 | methionine-tRNA synthetase 2 (mitochondrial) | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2008-04-30 | Mars2 | methionine-tRNA synthetase 2 (mitochondrial) | Mars2_predicted | methionine-tRNA synthetase 2 (mitochondrial) (predicted) | 'predicted' is removed | 2292626 | APPROVED |
2006-03-30 | Mars2_predicted | methionine-tRNA synthetase 2 (mitochondrial) (predicted) | RGD1311527_predicted | similar to hypothetical protein BC009115 (predicted) | Symbol and Name updated | 1299863 | APPROVED |
2005-01-20 | RGD1311527_predicted | similar to hypothetical protein BC009115 (predicted) | LOC316403_predicted | Symbol and Name status set to approved | 1331353 | APPROVED | |
2005-01-12 | LOC316403_predicted | similar to hypothetical protein BC009115 (predicted) | Symbol and Name status set to provisional | 70820 | PROVISIONAL |