Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Uri1 | Rat | (S)-nicotine | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | Nicotine results in increased expression of URI1 mRNA | CTD | PMID:17997037 | Uri1 | Rat | 1,2-dichloroethane | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | ethylene dichloride results in decreased expression of URI1 mRNA | CTD | PMID:28960355 | Uri1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of URI1 mRNA | CTD | PMID:19770486 | Uri1 | Rat | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | ISO | Uri1 (Mus musculus) | 6480464 | 3 more ... | CTD | PMID:19467301 | Uri1 | Rat | 3,3',5,5'-tetrabromobisphenol A | increases expression | EXP | | 6480464 | tetrabromobisphenol A results in increased expression of URI1 mRNA | CTD | PMID:27914987 | Uri1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of URI1 mRNA | CTD | PMID:31881267 | Uri1 | Rat | actinomycin D | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of URI1 protein | CTD | PMID:38460933 | Uri1 | Rat | all-trans-retinoic acid | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of URI1 mRNA | CTD | PMID:33167477 | Uri1 | Rat | antirheumatic drug | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of URI1 mRNA | CTD | PMID:24449571 | Uri1 | Rat | aristolochic acid A | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of URI1 mRNA | CTD | PMID:33212167 | Uri1 | Rat | arsenous acid | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of URI1 mRNA | CTD | PMID:22521957 | Uri1 | Rat | benzo[a]pyrene diol epoxide I | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:19150397 and PMID:20018196 | Uri1 | Rat | bisphenol A | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of URI1 mRNA | CTD | PMID:26063408 | Uri1 | Rat | bisphenol A | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of URI1 gene | CTD | PMID:31601247 | Uri1 | Rat | bisphenol A | increases methylation | ISO | URI1 (Homo sapiens) | 6480464 | bisphenol A results in increased methylation of URI1 gene | CTD | PMID:31601247 | Uri1 | Rat | bisphenol A | increases methylation | EXP | | 6480464 | bisphenol A results in increased methylation of URI1 gene | CTD | PMID:28505145 | Uri1 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of URI1 mRNA | CTD | PMID:25181051 and PMID:34947998 | Uri1 | Rat | cadmium dichloride | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of URI1 mRNA | CTD | PMID:38568856 | Uri1 | Rat | caffeine | affects phosphorylation | ISO | URI1 (Homo sapiens) | 6480464 | Caffeine affects the phosphorylation of URI1 protein | CTD | PMID:35688186 | Uri1 | Rat | carbon nanotube | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Uri1 | Rat | chlorpyrifos | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | Chlorpyrifos results in decreased expression of URI1 mRNA | CTD | PMID:37019170 | Uri1 | Rat | cisplatin | affects response to substance | ISO | URI1 (Homo sapiens) | 6480464 | URI1 protein affects the susceptibility to Cisplatin | CTD | PMID:16217747 | Uri1 | Rat | cisplatin | decreases response to substance | ISO | URI1 (Homo sapiens) | 6480464 | URI1 results in decreased susceptibility to Cisplatin | CTD | PMID:21397856 | Uri1 | Rat | cobalt dichloride | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of URI1 mRNA | CTD | PMID:19376846 | Uri1 | Rat | corosolic acid | multiple interactions | ISO | Uri1 (Mus musculus) | 6480464 | corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene] | CTD | PMID:32135139 | Uri1 | Rat | coumarin | affects phosphorylation | ISO | URI1 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of URI1 protein | CTD | PMID:35688186 | Uri1 | Rat | diarsenic trioxide | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of URI1 mRNA | CTD | PMID:22521957 | Uri1 | Rat | dicrotophos | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of URI1 mRNA | CTD | PMID:28302478 | Uri1 | Rat | dorsomorphin | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of URI1 mRNA | CTD | PMID:27188386 | Uri1 | Rat | doxorubicin | affects response to substance | ISO | URI1 (Homo sapiens) | 6480464 | URI1 protein affects the susceptibility to Doxorubicin | CTD | PMID:16217747 | Uri1 | Rat | enzyme inhibitor | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of URI1 protein | CTD | PMID:23301498 | Uri1 | Rat | fenofibrate | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | Fenofibrate results in increased expression of URI1 mRNA | CTD | PMID:21318169 | Uri1 | Rat | fenofibrate | multiple interactions | ISO | Uri1 (Mus musculus) | 6480464 | PPARA protein affects the reaction [Fenofibrate results in increased expression of URI1 mRNA] | CTD | PMID:21318169 | Uri1 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of URI1 mRNA | CTD | PMID:24136188 | Uri1 | Rat | folic acid | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of URI1 mRNA | CTD | PMID:25629700 | Uri1 | Rat | formaldehyde | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of URI1 mRNA | CTD | PMID:20655997 | Uri1 | Rat | fulvestrant | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of URI1 gene | CTD | PMID:31601247 | Uri1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of URI1 mRNA | CTD | PMID:33387578 | Uri1 | Rat | hexadecanoic acid | increases phosphorylation | ISO | URI1 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of URI1 protein | CTD | PMID:28073184 | Uri1 | Rat | kainic acid | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | Kainic Acid results in increased expression of URI1 mRNA | CTD | PMID:17997037 | Uri1 | Rat | leflunomide | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | leflunomide results in decreased expression of URI1 mRNA | CTD | PMID:28988120 | Uri1 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of URI1 mRNA | CTD | PMID:30467583 | Uri1 | Rat | methyl methanesulfonate | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of URI1 mRNA | CTD | PMID:23649840 | Uri1 | Rat | methylparaben | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | methylparaben results in increased expression of URI1 mRNA | CTD | PMID:31745603 | Uri1 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of URI1 mRNA | CTD | PMID:24136188 | Uri1 | Rat | nicotine | increases expression | ISO | Uri1 (Mus musculus) | 6480464 | Nicotine results in increased expression of URI1 mRNA | CTD | PMID:17997037 | Uri1 | Rat | nimesulide | increases expression | EXP | | 6480464 | nimesulide results in increased expression of URI1 mRNA | CTD | PMID:24136188 | Uri1 | Rat | Nutlin-3 | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of URI1 protein | CTD | PMID:38460933 | Uri1 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of URI1 mRNA | CTD | PMID:25729387 | Uri1 | Rat | phenobarbital | affects expression | ISO | Uri1 (Mus musculus) | 6480464 | Phenobarbital affects the expression of URI1 mRNA | CTD | PMID:23091169 | Uri1 | Rat | phenylmercury acetate | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of URI1 mRNA | CTD | PMID:26272509 | Uri1 | Rat | phenylmercury acetate | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of URI1 mRNA | CTD | PMID:27188386 | Uri1 | Rat | phorbol 13-acetate 12-myristate | increases methylation | ISO | Uri1 (Mus musculus) | 6480464 | Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene | CTD | PMID:32135139 | Uri1 | Rat | phorbol 13-acetate 12-myristate | multiple interactions | ISO | Uri1 (Mus musculus) | 6480464 | corosolic acid inhibits the reaction [Tetradecanoylphorbol Acetate results in increased methylation of URI1 gene] | CTD | PMID:32135139 | Uri1 | Rat | propiconazole | decreases expression | ISO | Uri1 (Mus musculus) | 6480464 | propiconazole results in decreased expression of URI1 mRNA | CTD | PMID:21278054 | Uri1 | Rat | quercetin | decreases phosphorylation | ISO | URI1 (Homo sapiens) | 6480464 | Quercetin results in decreased phosphorylation of URI1 protein | CTD | PMID:35688186 | Uri1 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of URI1 mRNA | CTD | PMID:19013527 | Uri1 | Rat | SB 431542 | multiple interactions | ISO | URI1 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of URI1 mRNA | CTD | PMID:27188386 | Uri1 | Rat | silicon dioxide | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased expression of URI1 mRNA | CTD | PMID:25351596 | Uri1 | Rat | sirolimus | decreases response to substance | ISO | URI1 (Homo sapiens) | 6480464 | URI1 results in decreased susceptibility to Sirolimus | CTD | PMID:21397856 | Uri1 | Rat | sunitinib | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of URI1 mRNA | CTD | PMID:31533062 | Uri1 | Rat | temozolomide | increases expression | ISO | URI1 (Homo sapiens) | 6480464 | Temozolomide results in increased expression of URI1 mRNA | CTD | PMID:31758290 | Uri1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of URI1 mRNA | CTD | PMID:23411599 and PMID:34492290 | Uri1 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of URI1 mRNA | CTD | PMID:25729387 | Uri1 | Rat | topotecan | decreases expression | EXP | | 6480464 | Topotecan results in decreased expression of URI1 mRNA | CTD | PMID:25729387 | Uri1 | Rat | topotecan | affects response to substance | ISO | URI1 (Homo sapiens) | 6480464 | URI1 protein affects the susceptibility to Topotecan | CTD | PMID:16217747 | Uri1 | Rat | triphenyl phosphate | affects expression | ISO | URI1 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of URI1 mRNA | CTD | PMID:37042841 | Uri1 | Rat | valdecoxib | increases expression | EXP | | 6480464 | valdecoxib results in increased expression of URI1 mRNA | CTD | PMID:24136188 | Uri1 | Rat | valproic acid | affects expression | ISO | URI1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of URI1 mRNA | CTD | PMID:25979313 | Uri1 | Rat | valproic acid | increases methylation | ISO | URI1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of URI1 gene | CTD | PMID:29154799 | Uri1 | Rat | valproic acid | decreases expression | ISO | URI1 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of URI1 mRNA | CTD | PMID:23179753 and PMID:27188386 | |