URI1 (URI1 prefoldin like chaperone) - Rat Genome Database

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Gene: URI1 (URI1 prefoldin like chaperone) Canis lupus familiaris
Analyze
Symbol: URI1
Name: URI1 prefoldin like chaperone
RGD ID: 12152116
Description: ENCODES a protein that exhibits chromatin binding (inferred); phosphatase inhibitor activity (inferred); phosphoprotein binding (inferred); INVOLVED IN cellular response to growth factor stimulus (inferred); cellular response to steroid hormone stimulus (inferred); negative regulation of intrinsic apoptotic signaling pathway (inferred); ASSOCIATED WITH carcinoma (ortholog); Experimental Neoplasms (ortholog); genetic disease (ortholog); FOUND IN RPAP3/R2TP/prefoldin-like complex (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: C1H19orf2; unconventional prefoldin RPB5 interactor 1; URI1, prefoldin like chaperone
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,528,706 - 121,612,200 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,530,203 - 121,614,909 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1120,897,395 - 120,980,814 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01122,157,827 - 122,241,288 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,157,537 - 122,241,879 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,737,554 - 121,820,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,344,096 - 121,427,703 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,409,100 - 122,492,731 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
URI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,528,706 - 121,612,200 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,530,203 - 121,614,909 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1120,897,395 - 120,980,814 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01122,157,827 - 122,241,288 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,157,537 - 122,241,879 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,737,554 - 121,820,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,344,096 - 121,427,703 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,409,100 - 122,492,731 (-)NCBIUU_Cfam_GSD_1.0
URI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381929,923,657 - 30,016,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1929,923,644 - 30,016,612 (+)EnsemblGRCh38hg38GRCh38
GRCh371930,414,564 - 30,507,519 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361935,125,265 - 35,198,456 (+)NCBINCBI36Build 36hg18NCBI36
Build 341935,125,264 - 35,198,451NCBI
Celera1927,127,113 - 27,200,278 (+)NCBICelera
Cytogenetic Map19q12NCBI
HuRef1926,921,938 - 27,014,764 (+)NCBIHuRef
CHM1_11930,414,913 - 30,507,875 (+)NCBICHM1_1
T2T-CHM13v2.01932,444,098 - 32,537,026 (+)NCBIT2T-CHM13v2.0
Uri1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39737,659,417 - 37,722,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl737,659,417 - 37,722,976 (-)EnsemblGRCm39 Ensembl
GRCm38737,959,992 - 38,023,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl737,959,992 - 38,023,551 (-)EnsemblGRCm38mm10GRCm38
MGSCv37738,745,011 - 38,804,571 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36737,668,762 - 37,728,302 (-)NCBIMGSCv36mm8
Celera733,115,193 - 33,174,905 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.29NCBI
Uri1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,783,157 - 99,845,787 (-)NCBIGRCr8
mRatBN7.2190,646,392 - 90,704,811 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,646,393 - 90,709,026 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx196,042,091 - 96,100,337 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,508,003 - 104,566,253 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0197,800,408 - 97,858,651 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,346,513 - 94,404,362 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,346,514 - 94,404,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0195,435,846 - 95,493,474 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,430,169 - 90,490,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1190,508,282 - 90,568,264 (-)NCBI
Celera184,979,704 - 85,037,972 (-)NCBICelera
Cytogenetic Map1q21NCBI
Uri1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554687,648,456 - 7,718,074 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554687,651,061 - 7,718,968 (-)NCBIChiLan1.0ChiLan1.0
URI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,898,365 - 35,991,008 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,895,424 - 37,988,046 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,865,190 - 26,939,510 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11935,621,130 - 35,694,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1935,601,872 - 35,694,273 (+)Ensemblpanpan1.1panPan2
Uri1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093496,238,300 - 6,266,629 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365705,376,658 - 5,419,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365705,379,253 - 5,419,595 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
URI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl640,023,595 - 40,110,536 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1640,043,320 - 40,110,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2635,409,250 - 35,476,422 (+)NCBISscrofa10.2Sscrofa10.2susScr3
URI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1625,005,512 - 25,078,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl625,005,316 - 25,078,541 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660732,546,698 - 2,620,295 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uri1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247945,060,061 - 5,125,969 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247945,059,961 - 5,126,771 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in URI1
958 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 5 5 20 4 6 4 6 6 12 8 10 6
Low 2 2 2
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts XM_005616795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_014120925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_022426483 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038453733 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468723 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038468724 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038529533 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593775 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038593777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_038657659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AAEX04000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAHUQ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAQRD010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAAUVH010000354 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  REHQ01000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSCAFT00000012164   ⟹   ENSCAFP00000011277
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1121,530,203 - 121,577,699 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000048433   ⟹   ENSCAFP00000038073
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1121,530,203 - 121,612,185 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000076676   ⟹   ENSCAFP00000059468
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1121,530,203 - 121,596,625 (-)Ensembl
RefSeq Acc Id: ENSCAFT00000077504   ⟹   ENSCAFP00000053133
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl1121,530,203 - 121,614,909 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845001866   ⟹   ENSCAFP00845001470
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1122,157,537 - 122,241,879 (-)Ensembl
RefSeq Acc Id: ENSCAFT00845001885   ⟹   ENSCAFP00845001483
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl1122,157,537 - 122,226,039 (-)Ensembl
RefSeq Acc Id: XM_005616795   ⟹   XP_005616852
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11121,528,706 - 121,612,200 (-)NCBI
Dog10K_Boxer_Tasha1120,897,395 - 120,980,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_022426483   ⟹   XP_022282191
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.11121,528,706 - 121,612,200 (-)NCBI
Dog10K_Boxer_Tasha1120,897,395 - 120,980,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_038453733   ⟹   XP_038309661
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
Dog10K_Boxer_Tasha1120,897,395 - 120,965,489 (-)NCBI
RefSeq Acc Id: XM_038468723   ⟹   XP_038324651
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11121,737,554 - 121,820,951 (-)NCBI
RefSeq Acc Id: XM_038468724   ⟹   XP_038324652
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.11121,737,554 - 121,805,615 (-)NCBI
RefSeq Acc Id: XM_038529531   ⟹   XP_038385459
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01122,409,100 - 122,492,731 (-)NCBI
RefSeq Acc Id: XM_038529532   ⟹   XP_038385460
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01122,409,100 - 122,492,731 (-)NCBI
RefSeq Acc Id: XM_038529533   ⟹   XP_038385461
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.01122,409,100 - 122,477,420 (-)NCBI
RefSeq Acc Id: XM_038593775   ⟹   XP_038449703
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01121,344,096 - 121,427,703 (-)NCBI
RefSeq Acc Id: XM_038593776   ⟹   XP_038449704
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01121,344,096 - 121,427,703 (-)NCBI
RefSeq Acc Id: XM_038593777   ⟹   XP_038449705
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.01121,344,096 - 121,412,196 (-)NCBI
RefSeq Acc Id: XM_038657656   ⟹   XP_038513584
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01122,157,827 - 122,241,288 (-)NCBI
RefSeq Acc Id: XM_038657658   ⟹   XP_038513586
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01122,157,827 - 122,241,288 (-)NCBI
RefSeq Acc Id: XM_038657659   ⟹   XP_038513587
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.01122,157,827 - 122,225,956 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_005616852   ⟸   XM_005616795
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q1W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_022282191   ⟸   XM_022426483
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVZ3 (UniProtKB/TrEMBL),   A0A8I3MI04 (UniProtKB/TrEMBL),   A0A8C0Q1W5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000053133   ⟸   ENSCAFT00000077504
RefSeq Acc Id: ENSCAFP00000038073   ⟸   ENSCAFT00000048433
RefSeq Acc Id: ENSCAFP00000059468   ⟸   ENSCAFT00000076676
RefSeq Acc Id: ENSCAFP00000011277   ⟸   ENSCAFT00000012164
RefSeq Acc Id: XP_038324651   ⟸   XM_038468723
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038324652   ⟸   XM_038468724
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038449704   ⟸   XM_038593776
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038449703   ⟸   XM_038593775
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038449705   ⟸   XM_038593777
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038513586   ⟸   XM_038657658
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q1W5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038513584   ⟸   XM_038657656
- Peptide Label: isoform X1
- UniProtKB: A0A8C0LVZ3 (UniProtKB/TrEMBL),   A0A8I3MI04 (UniProtKB/TrEMBL),   A0A8C0Q1W5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038513587   ⟸   XM_038657659
- Peptide Label: isoform X3
- UniProtKB: A0A8C0Q7Y4 (UniProtKB/TrEMBL),   A0A8I3MXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038309661   ⟸   XM_038453733
- Peptide Label: isoform X3
- UniProtKB: A0A8C0Q7Y4 (UniProtKB/TrEMBL),   A0A8I3MXX9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385460   ⟸   XM_038529532
- Peptide Label: isoform X2
- UniProtKB: A0A8C0Q1W5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385459   ⟸   XM_038529531
- Peptide Label: isoform X1
- UniProtKB: A0A8C0Q1W5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038385461   ⟸   XM_038529533
- Peptide Label: isoform X3
RefSeq Acc Id: ENSCAFP00845001470   ⟸   ENSCAFT00845001866
RefSeq Acc Id: ENSCAFP00845001483   ⟸   ENSCAFT00845001885


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000007606 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030000198 UniProtKB/TrEMBL
  ENSCAFG00040004171 UniProtKB/TrEMBL
  ENSCAFG00845001063 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000012164.6 UniProtKB/TrEMBL
  ENSCAFT00000048433.4 UniProtKB/TrEMBL
  ENSCAFT00030000309.1 UniProtKB/TrEMBL
  ENSCAFT00030000337.1 UniProtKB/TrEMBL
  ENSCAFT00040008070.1 UniProtKB/TrEMBL
  ENSCAFT00040008086.1 UniProtKB/TrEMBL
  ENSCAFT00845001866 ENTREZGENE
  ENSCAFT00845001866.1 UniProtKB/TrEMBL
  ENSCAFT00845001885 ENTREZGENE
  ENSCAFT00845001885.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro Prefoldin UniProtKB/TrEMBL
  Prefoldin_subunit_alpha UniProtKB/TrEMBL
NCBI Gene URI1 ENTREZGENE
PANTHER RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UniProtKB/TrEMBL
  UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 UniProtKB/TrEMBL
Pfam Prefoldin UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0A8C0LVZ3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q1W5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0Q7Y4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MI04 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3MXX9 ENTREZGENE, UniProtKB/TrEMBL
VGNC ID VGNC:48166 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 URI1  URI1 prefoldin like chaperone    URI1, prefoldin like chaperone  Symbol and/or name change 5135510 APPROVED