URI1 (URI1 prefoldin like chaperone) - Rat Genome Database

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Gene: URI1 (URI1 prefoldin like chaperone) Pan paniscus
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Symbol: URI1
Name: URI1 prefoldin like chaperone
RGD ID: 11838303
Description: ENCODES a protein that exhibits phosphoprotein binding (ortholog); RNA polymerase II complex binding (ortholog); INVOLVED IN cellular response to growth factor stimulus (ortholog); cellular response to steroid hormone stimulus (ortholog); negative regulation of intrinsic apoptotic signaling pathway (ortholog); ASSOCIATED WITH carcinoma (ortholog); Experimental Neoplasms (ortholog); Ovarian Neoplasms (ortholog); FOUND IN cytoplasm (ortholog); cytosol (ortholog); nucleoplasm (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: unconventional prefoldin RPB5 interactor 1; URI1, prefoldin like chaperone
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,898,365 - 35,991,008 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,895,424 - 37,988,046 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,865,190 - 26,939,510 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11935,621,130 - 35,694,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1935,601,872 - 35,694,273 (+)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
URI1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22035,898,365 - 35,991,008 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11937,895,424 - 37,988,046 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01926,865,190 - 26,939,510 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11935,621,130 - 35,694,390 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1935,601,872 - 35,694,273 (+)Ensemblpanpan1.1panPan2
URI1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381929,923,657 - 30,016,612 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1929,923,644 - 30,016,612 (+)EnsemblGRCh38hg38GRCh38
GRCh371930,414,564 - 30,507,519 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361935,125,265 - 35,198,456 (+)NCBINCBI36Build 36hg18NCBI36
Build 341935,125,264 - 35,198,451NCBI
Celera1927,127,113 - 27,200,278 (+)NCBICelera
Cytogenetic Map19q12NCBI
HuRef1926,921,938 - 27,014,764 (+)NCBIHuRef
CHM1_11930,414,913 - 30,507,875 (+)NCBICHM1_1
T2T-CHM13v2.01932,444,098 - 32,537,026 (+)NCBIT2T-CHM13v2.0
Uri1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39737,659,417 - 37,722,989 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl737,659,417 - 37,722,976 (-)EnsemblGRCm39 Ensembl
GRCm38737,959,992 - 38,023,564 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl737,959,992 - 38,023,551 (-)EnsemblGRCm38mm10GRCm38
MGSCv37738,745,011 - 38,804,571 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36737,668,762 - 37,728,302 (-)NCBIMGSCv36mm8
Celera733,115,193 - 33,174,905 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.29NCBI
Uri1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8199,783,157 - 99,845,787 (-)NCBIGRCr8
mRatBN7.2190,646,392 - 90,704,811 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl190,646,393 - 90,709,026 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx196,042,091 - 96,100,337 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01104,508,003 - 104,566,253 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0197,800,408 - 97,858,651 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0194,346,513 - 94,404,362 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl194,346,514 - 94,404,211 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0195,435,846 - 95,493,474 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4190,430,169 - 90,490,153 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1190,508,282 - 90,568,264 (-)NCBI
Celera184,979,704 - 85,037,972 (-)NCBICelera
Cytogenetic Map1q21NCBI
Uri1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554687,648,456 - 7,718,074 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554687,651,061 - 7,718,968 (-)NCBIChiLan1.0ChiLan1.0
URI1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11121,528,706 - 121,612,200 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1121,530,203 - 121,614,909 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1120,897,395 - 120,980,814 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01122,157,827 - 122,241,288 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1122,157,537 - 122,241,879 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11121,737,554 - 121,820,951 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01121,344,096 - 121,427,703 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01122,409,100 - 122,492,731 (-)NCBIUU_Cfam_GSD_1.0
Uri1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244093496,238,300 - 6,266,629 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365705,376,658 - 5,419,345 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365705,379,253 - 5,419,595 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
URI1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl640,023,595 - 40,110,536 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1640,043,320 - 40,110,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2635,409,250 - 35,476,422 (+)NCBISscrofa10.2Sscrofa10.2susScr3
URI1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1625,005,512 - 25,078,054 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl625,005,316 - 25,078,541 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660732,546,698 - 2,620,295 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Uri1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247945,060,061 - 5,125,969 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247945,059,961 - 5,126,771 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSPPAT00000040875   ⟹   ENSPPAP00000018146
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1935,601,872 - 35,693,751 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000040890   ⟹   ENSPPAP00000018161
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1935,602,534 - 35,694,273 (+)Ensembl
Ensembl Acc Id: ENSPPAT00000040897   ⟹   ENSPPAP00000018168
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl1935,621,124 - 35,693,751 (+)Ensembl
RefSeq Acc Id: XM_003816217   ⟹   XP_003816265
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,917,368 - 35,991,008 (+)NCBI
NHGRI_mPanPan11937,914,641 - 37,988,046 (+)NCBI
Mhudiblu_PPA_v01926,865,190 - 26,939,510 (+)NCBI
PanPan1.11935,621,130 - 35,694,390 (+)NCBI
Sequence:
RefSeq Acc Id: XM_003816218   ⟹   XP_003816266
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,917,372 - 35,991,008 (+)NCBI
NHGRI_mPanPan11937,914,641 - 37,988,046 (+)NCBI
Mhudiblu_PPA_v01926,865,190 - 26,939,510 (+)NCBI
PanPan1.11935,621,130 - 35,694,390 (+)NCBI
Sequence:
RefSeq Acc Id: XM_055104385   ⟹   XP_054960360
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,898,368 - 35,991,008 (+)NCBI
NHGRI_mPanPan11937,895,427 - 37,988,046 (+)NCBI
RefSeq Acc Id: XM_055104386   ⟹   XP_054960361
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,917,376 - 35,991,008 (+)NCBI
NHGRI_mPanPan11937,914,641 - 37,988,046 (+)NCBI
RefSeq Acc Id: XM_055104388   ⟹   XP_054960363
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,898,365 - 35,991,008 (+)NCBI
NHGRI_mPanPan11937,895,424 - 37,988,046 (+)NCBI
RefSeq Acc Id: XM_055104390   ⟹   XP_054960365
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22035,898,368 - 35,990,796 (+)NCBI
NHGRI_mPanPan11937,895,427 - 37,987,824 (+)NCBI
RefSeq Acc Id: XP_003816265   ⟸   XM_003816217
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_003816266   ⟸   XM_003816218
- Peptide Label: isoform X4
- Sequence:
Ensembl Acc Id: ENSPPAP00000018146   ⟸   ENSPPAT00000040875
Ensembl Acc Id: ENSPPAP00000018168   ⟸   ENSPPAT00000040897
Ensembl Acc Id: ENSPPAP00000018161   ⟸   ENSPPAT00000040890
RefSeq Acc Id: XP_054960363   ⟸   XM_055104388
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054960360   ⟸   XM_055104385
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054960365   ⟸   XM_055104390
- Peptide Label: isoform X6
- UniProtKB: A0A2R9ALB8 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054960361   ⟸   XM_055104386
- Peptide Label: isoform X3


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032180 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000040875.1 UniProtKB/TrEMBL
  ENSPPAT00000040890.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.370 UniProtKB/TrEMBL
InterPro Prefoldin UniProtKB/TrEMBL
  Prefoldin_subunit_alpha UniProtKB/TrEMBL
  RNA_pol_II_subunit5-mediator UniProtKB/TrEMBL
NCBI Gene URI1 ENTREZGENE
PANTHER RNA POLYMERASE II SUBUNIT 5-MEDIATING PROTEIN NNX3 UniProtKB/TrEMBL
  UNCONVENTIONAL PREFOLDIN RPB5 INTERACTOR 1 UniProtKB/TrEMBL
Pfam Prefoldin UniProtKB/TrEMBL
Superfamily-SCOP Prefoldin UniProtKB/TrEMBL
UniProt A0A2R9ALA3_PANPA UniProtKB/TrEMBL
  A0A2R9ALB8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-01-29 URI1  URI1 prefoldin like chaperone    URI1, prefoldin like chaperone  Symbol and/or name change 5135510 APPROVED