Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Kgd4 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MRPS36 mRNA | CTD | PMID:36331819 | Kgd4 | Rat | 1,2-dichloroethane | increases expression | ISO | Mrps36 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of MRPS36 mRNA | CTD | PMID:28960355 | Kgd4 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Mrps36 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MRPS36 mRNA | CTD | PMID:22206623 | Kgd4 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MRPS36 mRNA | CTD | PMID:22206623 | Kgd4 | Rat | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of KGD4 mRNA | CTD | PMID:17108234 | Kgd4 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of KGD4 mRNA | CTD | PMID:21215274 | Kgd4 | Rat | 2-hydroxypropanoic acid | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KGD4 mRNA | CTD | PMID:30851411 | Kgd4 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of KGD4 protein | CTD | PMID:34915118 | Kgd4 | Rat | 4,4'-diaminodiphenylmethane | affects expression | ISO | Mrps36 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane affects the expression of MRPS36 mRNA | CTD | PMID:18648102 | Kgd4 | Rat | benzo[a]pyrene | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | Benzo(a)pyrene promotes the reaction [AHR protein binds to MRPS36 promoter] | CTD | PMID:19654925 | Kgd4 | Rat | benzo[a]pyrene | increases methylation | ISO | KGD4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of KGD4 promoter | CTD | PMID:27901495 | Kgd4 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of KGD4 mRNA | CTD | PMID:25181051 | Kgd4 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of KGD4 mRNA | CTD | PMID:31129395 | Kgd4 | Rat | Brodifacoum | decreases expression | EXP | | 6480464 | bromfenacoum results in decreased expression of KGD4 protein | CTD | PMID:28903499 | Kgd4 | Rat | cadmium dichloride | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of MRPS36 mRNA | CTD | PMID:38382870 and PMID:38568856 | Kgd4 | Rat | caffeine | decreases phosphorylation | ISO | KGD4 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of KGD4 protein | CTD | PMID:35688186 | Kgd4 | Rat | carbon nanotube | increases expression | ISO | Mrps36 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of MRPS36 mRNA | CTD | PMID:25554681 | Kgd4 | Rat | cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of KGD4 mRNA | CTD | PMID:18500788 | Kgd4 | Rat | cisplatin | increases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of KGD4 mRNA | CTD | PMID:27594783 | Kgd4 | Rat | copper(II) sulfate | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of KGD4 mRNA | CTD | PMID:20599845 | Kgd4 | Rat | copper(II) sulfate | increases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of KGD4 mRNA | CTD | PMID:20599845 | Kgd4 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of KGD4 mRNA | CTD | PMID:21266533 | Kgd4 | Rat | dibutyl phthalate | decreases expression | ISO | Mrps36 (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of MRPS36 mRNA | CTD | PMID:21266533 | Kgd4 | Rat | dicrotophos | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of KGD4 mRNA | CTD | PMID:28302478 | Kgd4 | Rat | disodium selenite | increases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of KGD4 mRNA | CTD | PMID:18175754 | Kgd4 | Rat | finasteride | increases expression | EXP | | 6480464 | Finasteride results in increased expression of KGD4 mRNA | CTD | PMID:24136188 | Kgd4 | Rat | folic acid | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MRPS36 mRNA | CTD | PMID:22206623 | Kgd4 | Rat | FR900359 | increases phosphorylation | ISO | KGD4 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of KGD4 protein | CTD | PMID:37730182 | Kgd4 | Rat | ivermectin | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of KGD4 protein | CTD | PMID:32959892 | Kgd4 | Rat | lipopolysaccharide | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of KGD4 mRNA | CTD | PMID:31059760 | Kgd4 | Rat | N,N-diethyl-m-toluamide | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of KGD4 gene | CTD | PMID:33148267 | Kgd4 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of KGD4 mRNA | CTD | PMID:25729387 | Kgd4 | Rat | oxaliplatin | decreases expression | EXP | | 6480464 | Oxaliplatin results in decreased expression of KGD4 mRNA | CTD | PMID:25729387 | Kgd4 | Rat | ozone | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of MRPS36 mRNA | CTD | PMID:34911549 | Kgd4 | Rat | paracetamol | affects expression | ISO | Mrps36 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MRPS36 mRNA | CTD | PMID:17562736 | Kgd4 | Rat | paracetamol | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of KGD4 mRNA | CTD | PMID:25704631 and PMID:29067470 | Kgd4 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Mrps36 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of MRPS36 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of MRPS36 mRNA | CTD | PMID:36331819 | Kgd4 | Rat | perfluorooctanoic acid | increases expression | ISO | KGD4 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in increased expression of KGD4 protein | CTD | PMID:26879310 | Kgd4 | Rat | permethrin | multiple interactions | EXP | | 6480464 | [Permethrin co-treated with DEET] results in decreased methylation of KGD4 gene | CTD | PMID:33148267 | Kgd4 | Rat | pirinixic acid | increases expression | ISO | Mrps36 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of MRPS36 mRNA | CTD | PMID:17426115 more ... | Kgd4 | Rat | potassium chromate | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of KGD4 mRNA | CTD | PMID:22714537 | Kgd4 | Rat | rac-lactic acid | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Lactic Acid results in decreased expression of KGD4 mRNA | CTD | PMID:30851411 | Kgd4 | Rat | sodium fluoride | increases expression | ISO | Mrps36 (Mus musculus) | 6480464 | Sodium Fluoride results in increased expression of MRPS36 protein | CTD | PMID:28918527 | Kgd4 | Rat | sunitinib | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of KGD4 mRNA | CTD | PMID:31533062 | Kgd4 | Rat | titanium dioxide | decreases methylation | ISO | Mrps36 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MRPS36 gene | CTD | PMID:35295148 | Kgd4 | Rat | tolcapone | decreases expression | EXP | | 6480464 | Tolcapone results in decreased expression of KGD4 mRNA | CTD | PMID:24136188 | Kgd4 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [Oxaliplatin co-treated with Topotecan] results in decreased expression of KGD4 mRNA | CTD | PMID:25729387 | Kgd4 | Rat | triphenyl phosphate | affects expression | ISO | KGD4 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MRPS36 mRNA | CTD | PMID:37042841 | Kgd4 | Rat | triptonide | affects expression | ISO | Mrps36 (Mus musculus) | 6480464 | triptonide affects the expression of MRPS36 mRNA | CTD | PMID:33045310 | Kgd4 | Rat | tungsten | increases expression | ISO | Mrps36 (Mus musculus) | 6480464 | Tungsten results in increased expression of MRPS36 mRNA | CTD | PMID:30912803 | Kgd4 | Rat | zinc atom | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of KGD4 mRNA | CTD | PMID:22171008 | Kgd4 | Rat | zinc(0) | decreases expression | ISO | KGD4 (Homo sapiens) | 6480464 | Zinc deficiency results in decreased expression of KGD4 mRNA | CTD | PMID:22171008 | |