Wdr5b (WD repeat domain 5B) - Rat Genome Database

Name: Wdr5b
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

Gene: Wdr5b (WD repeat domain 5B) Rattus norvegicus

Analyze

Symbol:

Wdr5b

Name:

WD repeat domain 5B

RGD ID:

1308567

Description:

Predicted to enable histone binding activity. Predicted to be part of Set1C/COMPASS complex. Orthologous to human WDR5B (WD repeat domain 5B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; bisphenol A.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

LOC303907; WD repeat-containing protein 5B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	WDR5B (WD repeat domain 5B)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, PhylomeDB, Treefam
Mus musculus (house mouse):	Wdr5b (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Wdr5b (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	WDR5B (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	WDR5B (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Wdr5b (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	WDR5B (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	WDR5B (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Wdr5b (WD repeat domain 5B)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	WDR5 (WD repeat domain 5)	HGNC	OrthoDB
Homo sapiens (human):	MUC3A (mucin 3A, cell surface associated)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	WDR5B (WD repeat domain 5B)	Alliance	DIOPT (Ensembl Compara\|HGNC\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB)
Mus musculus (house mouse):	Wdr5b (WD repeat domain 5B)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	wdr5 (WD repeat domain 5)	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)
Saccharomyces cerevisiae (baker's yeast):	SWD3	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|PANTHER\|PhylomeDB)
Caenorhabditis elegans (roundworm):	wdr-5.3	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PhylomeDB)
Caenorhabditis elegans (roundworm):	wdr-5.1	Alliance	DIOPT (Ensembl Compara\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	wds	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER\|PhylomeDB)
Xenopus tropicalis (tropical clawed frog):	wdr5	Alliance	DIOPT (Ensembl Compara\|OrthoFinder\|PANTHER)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,216,266 - 78,218,125 (-)	NCBI		GRCr8
mRatBN7.2	11	64,710,945 - 64,712,804 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,710,355 - 64,712,807 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	73,536,288 - 73,538,147 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,198,550 - 66,200,409 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,229,798 - 65,231,657 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	67,645,959 - 67,647,818 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	67,645,965 - 67,647,818 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	70,733,436 - 70,735,295 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	66,546,008 - 66,547,867 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	66,603,598 - 66,605,456 (-)	NCBI
Celera	11	64,176,936 - 64,178,795 (-)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alkaptonuria (ISO)

familial hypocalciuric hypercalcemia (ISO)

Primary Lymphedema with Myelodysplasia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

17alpha-ethynylestradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

4,4'-diaminodiphenylmethane (ISO)

aristolochic acid A (ISO)

avobenzone (ISO)

bisphenol A (EXP,ISO)

butanal (ISO)

carbamazepine (ISO)

CGP 52608 (ISO)

choline (ISO)

cobalt dichloride (EXP)

copper(II) sulfate (ISO)

cyclosporin A (ISO)

Dibutyl phosphate (ISO)

dioxygen (ISO)

elemental selenium (ISO)

folic acid (ISO)

formaldehyde (ISO)

gentamycin (EXP)

L-methionine (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

paracetamol (EXP,ISO)

potassium chloride (ISO)

quercetin (ISO)

selenium atom (ISO)

silicon dioxide (ISO)

sodium dodecyl sulfate (ISO)

Soman (EXP)

tebuconazole (ISO)

thioacetamide (EXP)

triphenyl phosphate (ISO)

urethane (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Cellular Component

Set1C/COMPASS complex (IBA)

Molecular Function

histone binding (IBA)

protein binding (IPI)

References

References - curated

#	Reference Title	Reference Citation
1.	PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator.	Brown SA, etal., Science. 2005 Apr 29;308(5722):693-6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA pipeline	RGD automated data pipeline
4.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:15489334

Genomics

Comparative Map Data

Wdr5b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	78,216,266 - 78,218,125 (-)	NCBI		GRCr8
mRatBN7.2	11	64,710,945 - 64,712,804 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	64,710,355 - 64,712,807 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	73,536,288 - 73,538,147 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	66,198,550 - 66,200,409 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	65,229,798 - 65,231,657 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	67,645,959 - 67,647,818 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	67,645,965 - 67,647,818 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	70,733,436 - 70,735,295 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	66,546,008 - 66,547,867 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	66,603,598 - 66,605,456 (-)	NCBI
Celera	11	64,176,936 - 64,178,795 (-)	NCBI		Celera
Cytogenetic Map	11	q22	NCBI

WDR5B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	122,411,846 - 122,416,062 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	122,411,846 - 122,416,062 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	122,130,693 - 122,134,909 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	123,613,390 - 123,617,572 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	123,613,389 - 123,617,572	NCBI
Celera	3	120,540,328 - 120,544,510 (-)	NCBI		Celera
Cytogenetic Map	3	q21.1	NCBI
HuRef	3	119,504,011 - 119,508,193 (-)	NCBI		HuRef
CHM1_1	3	122,094,185 - 122,098,367 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	3	125,131,401 - 125,135,617 (-)	NCBI		T2T-CHM13v2.0

Wdr5b
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	35,861,560 - 35,863,344 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	35,861,560 - 35,864,298 (+)	Ensembl		GRCm39 Ensembl
GRCm38	16	36,041,190 - 36,042,974 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	36,041,190 - 36,043,928 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	36,041,276 - 36,043,060 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	35,960,937 - 35,962,721 (+)	NCBI		MGSCv36	mm8
Celera	16	36,521,798 - 36,523,582 (+)	NCBI		Celera
Cytogenetic Map	16	B3	NCBI
cM Map	16	25.43	NCBI

Wdr5b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955427	21,698,917 - 21,699,888 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955427	21,698,766 - 21,700,390 (-)	NCBI	ChiLan1.0	ChiLan1.0

WDR5B
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	120,357,926 - 120,361,745 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	120,360,418 - 120,366,525 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	119,503,001 - 119,506,814 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	126,408,696 - 126,412,482 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	126,410,902 - 126,411,894 (-)	Ensembl	panpan1.1		panPan2

WDR5B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	25,554,218 - 25,557,025 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	25,555,419 - 25,556,408 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	25,578,548 - 25,581,379 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	25,789,314 - 25,792,140 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	25,789,314 - 25,792,105 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	25,586,303 - 25,589,137 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	25,629,685 - 25,632,491 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	26,187,207 - 26,190,033 (-)	NCBI		UU_Cfam_GSD_1.0

Wdr5b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	128,787,032 - 128,794,125 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936536	8,728,735 - 8,730,367 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936536	8,727,881 - 8,731,067 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

WDR5B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	138,109,848 - 138,113,646 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	138,109,758 - 138,113,638 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	147,720,711 - 147,723,427 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

WDR5B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	58,444,586 - 58,446,316 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	58,445,149 - 58,446,141 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	107,895,882 - 107,899,147 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Wdr5b
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624912	764,076 - 766,647 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624912	762,893 - 766,690 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Wdr5b
2 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	107
Count of miRNA genes:	92
Interacting mature miRNAs:	96
Transcripts:	ENSRNOT00000003068
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
724554	Iddm17	Insulin dependent diabetes mellitus QTL 17		0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	18976208	86241447	Rat
10058952	Gmadr6	Adrenal mass QTL 6	2.29	0.0072	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	22959403	67959403	Rat
8694376	Bw156	Body weight QTL 156	2.25	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
9590313	Scort20	Serum corticosterone level QTL 20	6.51	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	11	23280456	68280456	Rat
9589032	Epfw10	Epididymal fat weight QTL 10	9.29	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	11	23280456	68280456	Rat
8694424	Bw162	Body weight QTL 162	3.8	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	11	23280456	68280456	Rat
724563	Uae10	Urinary albumin excretion QTL 10	6		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	11	27672410	82846715	Rat
1300110	Stl7	Serum triglyceride level QTL 7	4.64		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	11	29528418	82566702	Rat
2298551	Neuinf10	Neuroinflammation QTL 10	3.7		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	11	31239134	78851519	Rat
70180	BpQTLcluster10	Blood pressure QTL cluster 10	3.19		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	11	34918041	79918041	Rat
1300135	Rf19	Renal function QTL 19	3.38		blood creatinine amount (VT:0005328)	creatinine clearance (CMO:0000765)	11	40946188	82566702	Rat
2312566	Glom20	Glomerulus QTL 20	3.6	0.001	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	44285759	82566702	Rat
1581565	Pur10	Proteinuria QTL 10		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
1581572	Uae35	Urinary albumin excretion QTL 35		0.0001	urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	11	44803318	82846466	Rat
4889859	Pur28	Proteinuria QTL 28	19.5	0.001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	11	45459323	75190161	Rat
724561	Plsm4	Polydactyly-luxate syndrome (PLS) morphotypes QTL 4		0.0003	forelimb integrity trait (VT:0010562)	front foot phalanges count (CMO:0001947)	11	54457534	86241447	Rat
4889521	Gluco62	Glucose level QTL 62	2.82	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	11	55136729	82993457	Rat
7411658	Foco27	Food consumption QTL 27	16.2	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	11	56351424	86241447	Rat
631506	Bp104	Blood pressure QTL 104	2.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	11	59802794	82566545	Rat
70208	Niddm22	Non-insulin dependent diabetes mellitus QTL 22	3.61		blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	11	59802794	82566553	Rat
10058954	Gmadr7	Adrenal mass QTL 7	2.49	0.0049	adrenal gland mass (VT:0010420)	both adrenal glands wet weight to body weight ratio (CMO:0002411)	11	60346590	86241447	Rat

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium									4		5	5
Low	3	43	57	41	19	41	8	11	70	35	36	6	8
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001024766	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097449	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473967	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000003068 ⟹ ENSRNOP00000003068

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	64,710,355 - 64,712,807 (-)	Ensembl
Rnor_6.0 Ensembl	11	67,645,965 - 67,647,818 (-)	Ensembl

RefSeq Acc Id:

NM_001024766 ⟹ NP_001019937

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	78,216,266 - 78,218,125 (-)	NCBI
mRatBN7.2	11	64,710,945 - 64,712,804 (-)	NCBI
Rnor_6.0	11	67,645,959 - 67,647,818 (-)	NCBI
Rnor_5.0	11	70,733,436 - 70,735,295 (-)	NCBI
RGSC_v3.4	11	66,546,008 - 66,547,867 (-)	RGD
Celera	11	64,176,936 - 64,178,795 (-)	RGD

Sequence:

show sequence

CGCAGCCTGGAAGGGTGTGTACCTGGCGTCGTCCTGGGCTCTGCTTGAGCCTCTCAAATCCTGA
TTCGTGTGACGTCATCCGTTGCTCACTATTTCCCGACATTTTGGAGCTTGGGAGGGCGTGGAAG
ACGACTTTAGGTGCAGCCCCCAATCACCGCTGGTCGTCTTAGTCCTTTAACAGCACCCGGCACG
ATTACGGATCCCAGGACCACTGTGATCTGTGATGCTATCGAAGAAAGCAAGAGCGGAGTGTTCC
AAACTTTGCTGTTGACTGGGAACGGACCTTAAAGAGGATCTCCTGTTACAATCAAAACCGTCCG
CCTTCCAACGGCAAGTTTTATCTTCTGTAAGGTTTGGGGCCGGGGCCGGACGCCTGCGCAGATT
GTCGAGCCGGATCCATGGCAACCGAGCATCTGCCAGCGGAGAGAGCACAGTCGCCCCTCTCTGC
CCCACAGCGGGTGGAAGAGCCACAGAAACCCAACTATGCTCTCAGACTTACTCTTGCAGGGCAC
TCGGCGGCCATATCATCTGTTAAGTTTAGTCCTAATGGCGAGTGGCTAGCAAGTTCTGCAGCTG
ATGCACTAATTATAATTTGGGGAGCTTATGATGGGAAATGTAAGAAAACACTTTATGGTCACAG
TCTGGAAATATCAGATGTTGCCTGGTCTTCAGATTCTAGTCGTCTGGTTTCTGCCTCAGACGAT
AAAACTCTCAAGTTATGGGATGTGAGATCTGGAAAATGTTTGAAAACACTGAAGGGGCACAGCG
ATTTCGTCTTCTGCTGTGATTTCAACCCACCATCCAACCTCATCGTTTCAGGATCTTTTGATGA
GAGTGTGAAAATATGGGAAGTGAAAACAGGAAAGTGCCTCAAGACTTTGTCTGCTCATTCGGAC
CCCATTTCTGCCGTACATTTTCATTGTAATGGGTCCTTGATAGTGTCCGGAAGCTATGATGGTC
TTTGTAGAATTTGGGATGCTGCGTCAGGCCAGTGTTTAAGAACACTTGCTGATGAAGGTAACCC
TCCCGTGTCTTTTGTAAAATTTTCTCCAAATGGTAAATACATTCTCACTGCAACTTTGGACAGT
ACTCTTAAACTGTGGGACTACAGTAGGGGCAGATGCCTGAAGACATACACTGGTCATAAGAATG
AGAAATACTGTATATTTGCCAGTTTCTCTGTTACTGGCAGAAAGTGGGTTGTGTCTGGTTCAGA
GGACAACATGGTTTACATCTGGAACCTTCAGACCAAAGAGATTGTACAGAGGTTACAAGGTCAC
ACAGATGTTGTGATCTCAGCAGCCTGTCACCCTACAGAAAACATCATTGCATCGGCAGCATTAG
AAAACGACAAGACAATTAAAATATGGTCGAGTGACTACTGATGAGGAAAGCCAAGTTAGACACA
AAACTGAAAGGATGGTTTCTTTGAATTCTGGCATGGCTCAACAAATTGTCCTTGTATGAGACTG
AGACATTTTAACTTGCAAAATGAGACCCTGTAAAAAGTCTAGGACCTGGGGTTTTTGAGGCCTA
ATCTCAAGGCCTGCTAGAATCTCGTGTGTTCATCCCTGGACAGTGTCTCGTTCTCTTTCAATAG
CTTTCCCAGAGGGGGATGGTTTTTGGAATATCTAGAAAGGTGACACAACAGGATGACTGAGGGG
GAGGAGGGACCTGTAGCCTCTGGTTTGGGAGGTCATTAAGGGCAGTGACATTAGGGAGGTACTG
GGAGAATTGGAGATGTTTTACATTTCACTCGAATATTTTTGGTGTTATTCTACACGATGGGGCA
TCAAATTGCCAAATTAATCTGTCAAGTTGGGGACAATAAATCACAGTCTGGTTTGTTCTATGAA
TGAAAAAAAAAAAAAAAAAAAAAAAAAA

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Protein Sequences


Protein RefSeqs	NP_001019937	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97449	(Get FASTA)	NCBI Sequence Viewer
	EDM11297	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000003068
	ENSRNOP00000003068.2
	ENSRNOP00055024013
	ENSRNOP00060039419
	ENSRNOP00065029379
GenBank Protein	Q4V8C4	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001019937 ⟸ NM_001024766

- UniProtKB:

Q4V8C4 (UniProtKB/Swiss-Prot), A6IRE4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MATEHLPAERAQSPLSAPQRVEEPQKPNYALRLTLAGHSAAISSVKFSPNGEWLASSAADALII
IWGAYDGKCKKTLYGHSLEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSDFVFC
CDFNPPSNLIVSGSFDESVKIWEVKTGKCLKTLSAHSDPISAVHFHCNGSLIVSGSYDGLCRIW
DAASGQCLRTLADEGNPPVSFVKFSPNGKYILTATLDSTLKLWDYSRGRCLKTYTGHKNEKYCI
FASFSVTGRKWVVSGSEDNMVYIWNLQTKEIVQRLQGHTDVVISAACHPTENIIASAALENDKT
IKIWSSDY

hide sequence

RefSeq Acc Id:

ENSRNOP00000003068 ⟸ ENSRNOT00000003068

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8C4-F1-model_v2	AlphaFold	Q4V8C4	1-328	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1308567	AgrOrtholog
BioCyc Gene	G2FUF-21210	BioCyc
Ensembl Genes	ENSRNOG00000002253	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
	ENSRNOG00055017662	UniProtKB/Swiss-Prot
	ENSRNOG00060027302	UniProtKB/Swiss-Prot
	ENSRNOG00065021458	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000003068	ENTREZGENE
	ENSRNOT00000003068.4	UniProtKB/Swiss-Prot
	ENSRNOT00055029882	UniProtKB/Swiss-Prot
	ENSRNOT00060047355	UniProtKB/Swiss-Prot
	ENSRNOT00065036463	UniProtKB/Swiss-Prot
Gene3D-CATH	2.130.10.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7456711	IMAGE-MGC_LOAD
InterPro	G-protein_beta_WD-40_rep	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40/YVTN_repeat-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40_repeat_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:303907	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:114509	IMAGE-MGC_LOAD
NCBI Gene	303907	ENTREZGENE
PANTHER	WD REPEAT-CONTAINING PROTEIN 5B	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD40 REPEAT PROTEIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Wdr5b	PhenoGen
PIRSF	GN-bd_beta	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	GPROTEINBRPT	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	WD_REPEATS_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	WD_REPEATS_REGION	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000002253	RatGTEx
	ENSRNOG00055017662	RatGTEx
	ENSRNOG00060027302	RatGTEx
	ENSRNOG00065021458	RatGTEx
SMART	WD40	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF50978	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A6IRE4	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8C4	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Wdr5b	WD repeat domain 5B	Wdr5b_predicted	WD repeat domain 5B (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Wdr5b_predicted	WD repeat domain 5B (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar