Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rprd1a | Rat | (2,4,5-trichlorophenoxy)acetic acid | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | 2 more ... | CTD | PMID:18579281 | Rprd1a | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Rprd1a (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RPRD1A mRNA | CTD | PMID:22206623 | Rprd1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Rprd1a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of RPRD1A mRNA | CTD | PMID:21570461 | Rprd1a | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of RPRD1A mRNA | CTD | PMID:25975270 | Rprd1a | Rat | 2-methylcholine | affects expression | ISO | RPRD1A (Homo sapiens) | 6480464 | beta-methylcholine affects the expression of RPRD1A mRNA | CTD | PMID:21179406 | Rprd1a | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of RPRD1A mRNA | CTD | PMID:20188158 | Rprd1a | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Fenretinide results in increased expression of RPRD1A mRNA | CTD | PMID:28973697 | Rprd1a | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of RPRD1A mRNA | CTD | PMID:30047161 | Rprd1a | Rat | aflatoxin B1 | increases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of RPRD1A mRNA | CTD | PMID:27153756 | Rprd1a | Rat | all-trans-retinoic acid | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Tretinoin results in increased expression of RPRD1A mRNA | CTD | PMID:16788091 | Rprd1a | Rat | all-trans-retinoic acid | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of RPRD1A mRNA | CTD | PMID:33167477 | Rprd1a | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of RPRD1A mRNA | CTD | PMID:30047161 | Rprd1a | Rat | benzo[a]pyrene | increases mutagenesis | ISO | RPRD1A (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of RPRD1A gene | CTD | PMID:25435355 | Rprd1a | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of RPRD1A mRNA | CTD | PMID:25181051 | Rprd1a | Rat | bisphenol A | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of RPRD1A protein | CTD | PMID:37567409 | Rprd1a | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of RPRD1A mRNA | CTD | PMID:34947998 | Rprd1a | Rat | bisphenol A | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [[ginger extract results in increased abundance of Oils and Volatile] which co-treated with bisphenol A] affects the expression of RPRD1A protein | CTD | PMID:33376534 | Rprd1a | Rat | bisphenol F | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | bisphenol F results in increased expression of RPRD1A mRNA | CTD | PMID:38685157 | Rprd1a | Rat | cadmium dichloride | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of RPRD1A mRNA | CTD | PMID:38568856 | Rprd1a | Rat | carbon nanotube | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Nanotubes and Carbon analog results in decreased expression of RPRD1A mRNA | CTD | PMID:25620056 | Rprd1a | Rat | chloropicrin | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of RPRD1A mRNA | CTD | PMID:26352163 | Rprd1a | Rat | copper(II) sulfate | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of RPRD1A mRNA | CTD | PMID:19549813 | Rprd1a | Rat | copper(II) sulfate | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Copper Sulfate results in decreased expression of RPRD1A mRNA | CTD | PMID:18579281 | Rprd1a | Rat | coumarin | increases phosphorylation | ISO | RPRD1A (Homo sapiens) | 6480464 | coumarin results in increased phosphorylation of RPRD1A protein | CTD | PMID:35688186 | Rprd1a | Rat | cyclosporin A | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of RPRD1A mRNA | CTD | PMID:25562108 | Rprd1a | Rat | Dibutyl phosphate | affects expression | ISO | RPRD1A (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of RPRD1A mRNA | CTD | PMID:37042841 | Rprd1a | Rat | dicrotophos | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of RPRD1A mRNA | CTD | PMID:28302478 | Rprd1a | Rat | dorsomorphin | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Rprd1a | Rat | doxorubicin | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of RPRD1A mRNA | CTD | PMID:29803840 | Rprd1a | Rat | entinostat | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | entinostat results in decreased expression of RPRD1A mRNA | CTD | PMID:27188386 | Rprd1a | Rat | enzyme inhibitor | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of RPRD1A protein | CTD | PMID:23301498 | Rprd1a | Rat | ethanol | multiple interactions | ISO | Rprd1a (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of RPRD1A mRNA | CTD | PMID:30319688 | Rprd1a | Rat | ethyl methanesulfonate | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of RPRD1A mRNA | CTD | PMID:23649840 | Rprd1a | Rat | fenthion | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | Fenthion results in decreased expression of RPRD1A mRNA | CTD | PMID:34813904 | Rprd1a | Rat | folic acid | multiple interactions | ISO | Rprd1a (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of RPRD1A mRNA | CTD | PMID:22206623 | Rprd1a | Rat | formaldehyde | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of RPRD1A mRNA | CTD | PMID:23649840 | Rprd1a | Rat | FR900359 | increases phosphorylation | ISO | RPRD1A (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of RPRD1A protein | CTD | PMID:37730182 | Rprd1a | Rat | ivermectin | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of RPRD1A protein | CTD | PMID:32959892 | Rprd1a | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of RPRD1A mRNA | CTD | PMID:30047161 | Rprd1a | Rat | methyl methanesulfonate | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of RPRD1A mRNA | CTD | PMID:23649840 | Rprd1a | Rat | methylmercury chloride | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of RPRD1A mRNA | CTD | PMID:28001369 | Rprd1a | Rat | N-ethyl-N-nitrosourea | increases mutagenesis | EXP | | 6480464 | Ethylnitrosourea results in increased mutagenesis of RPRD1A gene | CTD | PMID:16495775 | Rprd1a | Rat | phenylmercury acetate | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of RPRD1A mRNA | CTD | PMID:26272509 | Rprd1a | Rat | phenylmercury acetate | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RPRD1A mRNA | CTD | PMID:27188386 | Rprd1a | Rat | pirinixic acid | multiple interactions | ISO | Rprd1a (Mus musculus) | 6480464 | [pirinixic acid co-treated with PPARA] results in decreased expression of RPRD1A mRNA | CTD | PMID:20813756 | Rprd1a | Rat | pirinixic acid | decreases expression | ISO | Rprd1a (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of RPRD1A mRNA | CTD | PMID:20813756 and PMID:23811191 | Rprd1a | Rat | SB 431542 | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Rprd1a | Rat | sodium arsenite | affects expression | ISO | RPRD1A (Homo sapiens) | 6480464 | sodium arsenite affects the expression of RPRD1A mRNA | CTD | PMID:29319823 | Rprd1a | Rat | sodium arsenite | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | sodium arsenite results in increased expression of RPRD1A mRNA | CTD | PMID:36209798 | Rprd1a | Rat | sodium arsenite | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of RPRD1A mRNA | CTD | PMID:38568856 | Rprd1a | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of RPRD1A mRNA | CTD | PMID:30047161 | Rprd1a | Rat | sunitinib | increases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Sunitinib results in increased expression of RPRD1A mRNA | CTD | PMID:31533062 | Rprd1a | Rat | titanium dioxide | decreases methylation | ISO | Rprd1a (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of RPRD1A gene | CTD | PMID:35295148 | Rprd1a | Rat | triphenyl phosphate | affects expression | ISO | RPRD1A (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of RPRD1A mRNA | CTD | PMID:37042841 | Rprd1a | Rat | troglitazone | increases expression | ISO | Rprd1a (Mus musculus) | 6480464 | troglitazone results in increased expression of RPRD1A mRNA | CTD | PMID:28973697 | Rprd1a | Rat | valproic acid | affects expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Valproic Acid affects the expression of RPRD1A mRNA | CTD | PMID:23179753 and PMID:25979313 | Rprd1a | Rat | valproic acid | increases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of RPRD1A mRNA | CTD | PMID:28001369 and PMID:29154799 | Rprd1a | Rat | valproic acid | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of RPRD1A mRNA | CTD | PMID:19101580 more ... | Rprd1a | Rat | valproic acid | multiple interactions | ISO | RPRD1A (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of RPRD1A mRNA | CTD | PMID:27188386 | Rprd1a | Rat | vincristine | decreases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | Vincristine results in decreased expression of RPRD1A mRNA | CTD | PMID:23649840 | Rprd1a | Rat | vorinostat | increases expression | ISO | RPRD1A (Homo sapiens) | 6480464 | vorinostat results in increased expression of RPRD1A mRNA | CTD | PMID:27188386 | |