Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Sh3tc1 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SH3TC1 mRNA | CTD | PMID:22206623 | Sh3tc1 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of SH3TC1 mRNA | CTD | PMID:21570461 | Sh3tc1 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of SH3TC1 mRNA | CTD | PMID:21346803 | Sh3tc1 | Rat | 4,4'-sulfonyldiphenol | increases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | bisphenol S results in increased expression of SH3TC1 mRNA | CTD | PMID:30951980 | Sh3tc1 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | Sh3tc1 (Mus musculus) | 6480464 | bisphenol S results in decreased methylation of SH3TC1 exon | CTD | PMID:33297965 | Sh3tc1 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of SH3TC1 mRNA | CTD | PMID:24780913 | Sh3tc1 | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of SH3TC1 mRNA | CTD | PMID:31881176 | Sh3tc1 | Rat | adefovir pivoxil | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | adefovir dipivoxil results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | antirheumatic drug | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Antirheumatic Agents results in decreased expression of SH3TC1 mRNA | CTD | PMID:24449571 | Sh3tc1 | Rat | benzo[a]pyrene | decreases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of SH3TC1 mRNA | CTD | PMID:21569818 | Sh3tc1 | Rat | benzo[a]pyrene | affects methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of SH3TC1 5' UTR and Benzo(a)pyrene affects the methylation of SH3TC1 intron | CTD | PMID:27901495 and PMID:30157460 | Sh3tc1 | Rat | benzo[a]pyrene | decreases methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of SH3TC1 exon and Benzo(a)pyrene results in decreased methylation of SH3TC1 promoter | CTD | PMID:27901495 | Sh3tc1 | Rat | benzo[e]pyrene | increases methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of SH3TC1 intron | CTD | PMID:30157460 | Sh3tc1 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SH3TC1 mRNA | CTD | PMID:25181051 | Sh3tc1 | Rat | bisphenol A | decreases methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of SH3TC1 gene | CTD | PMID:31601247 | Sh3tc1 | Rat | bisphenol A | increases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | bisphenol A results in increased expression of SH3TC1 mRNA | CTD | PMID:33221593 | Sh3tc1 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of SH3TC1 mRNA | CTD | PMID:34947998 | Sh3tc1 | Rat | bisphenol A | affects expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | bisphenol A affects the expression of SH3TC1 mRNA | CTD | PMID:30903817 | Sh3tc1 | Rat | butan-1-ol | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SH3TC1 mRNA | CTD | PMID:29432896 | Sh3tc1 | Rat | cadmium atom | multiple interactions | ISO | Sh3tc1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SH3TC1 mRNA | CTD | PMID:37325564 | Sh3tc1 | Rat | cadmium dichloride | increases methylation | EXP | | 6480464 | Cadmium Chloride results in increased methylation of SH3TC1 promoter | CTD | PMID:22457795 | Sh3tc1 | Rat | cadmium dichloride | multiple interactions | ISO | Sh3tc1 (Mus musculus) | 6480464 | [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SH3TC1 mRNA | CTD | PMID:37325564 | Sh3tc1 | Rat | cadmium dichloride | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Cadmium Chloride results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | calcitriol | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of SH3TC1 mRNA | CTD | PMID:16002434 and PMID:21592394 | Sh3tc1 | Rat | calcitriol | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SH3TC1 mRNA | CTD | PMID:21592394 | Sh3tc1 | Rat | carbon nanotube | decreases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | Nanotubes and Carbon results in decreased expression of SH3TC1 mRNA | CTD | PMID:25554681 | Sh3tc1 | Rat | chloroacetaldehyde | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | chloroacetaldehyde results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | chlorpyrifos | increases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of SH3TC1 mRNA | CTD | PMID:37019170 | Sh3tc1 | Rat | cidofovir anhydrous | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Cidofovir results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | cisplatin | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of SH3TC1 mRNA | CTD | PMID:27594783 | Sh3tc1 | Rat | clothianidin | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | clothianidin results in increased expression of SH3TC1 mRNA | CTD | PMID:29044138 | Sh3tc1 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of SH3TC1 mRNA | CTD | PMID:24386269 | Sh3tc1 | Rat | copper(II) chloride | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | cupric chloride results in increased expression of SH3TC1 mRNA | CTD | PMID:38568856 | Sh3tc1 | Rat | copper(II) sulfate | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of SH3TC1 mRNA | CTD | PMID:19549813 | Sh3tc1 | Rat | cyclosporin A | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of SH3TC1 mRNA | CTD | PMID:20106945 more ... | Sh3tc1 | Rat | cyclosporin A | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | dioxygen | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of SH3TC1 mRNA | CTD | PMID:21551480 | Sh3tc1 | Rat | fenofibrate | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Fenofibrate results in increased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | formaldehyde | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of SH3TC1 mRNA | CTD | PMID:27664576 | Sh3tc1 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of SH3TC1 mRNA | CTD | PMID:33387578 | Sh3tc1 | Rat | hydroquinone | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | hydroquinone results in increased expression of SH3TC1 mRNA | CTD | PMID:31256213 | Sh3tc1 | Rat | ibuprofen | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Ibuprofen results in increased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | ifosfamide | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Ifosfamide results in decreased expression of SH3TC1 mRNA | CTD | PMID:25596134 | Sh3tc1 | Rat | leflunomide | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | leflunomide results in increased expression of SH3TC1 mRNA | CTD | PMID:28988120 | Sh3tc1 | Rat | lipopolysaccharide | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Sh3tc1 | Rat | lipopolysaccharide | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Lipopolysaccharides results in decreased expression of SH3TC1 mRNA | CTD | PMID:35811015 | Sh3tc1 | Rat | methapyrilene | increases methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of SH3TC1 intron | CTD | PMID:30157460 | Sh3tc1 | Rat | N(4)-hydroxycytidine | decreases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | N(4)-hydroxycytidine results in decreased expression of SH3TC1 mRNA | CTD | PMID:37748715 | Sh3tc1 | Rat | nickel atom | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Nickel results in increased expression of SH3TC1 mRNA | CTD | PMID:24768652 and PMID:25583101 | Sh3tc1 | Rat | paracetamol | affects expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | Acetaminophen affects the expression of SH3TC1 mRNA | CTD | PMID:17562736 | Sh3tc1 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of SH3TC1 mRNA | CTD | PMID:33387578 | Sh3tc1 | Rat | pirinixic acid | increases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of SH3TC1 mRNA | CTD | PMID:23811191 | Sh3tc1 | Rat | propanal | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of SH3TC1 mRNA | CTD | PMID:26079696 | Sh3tc1 | Rat | prothioconazole | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | prothioconazole results in increased expression of SH3TC1 mRNA | CTD | PMID:35048155 | Sh3tc1 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [S-(1 more ... | CTD | PMID:35811015 | Sh3tc1 | Rat | sodium arsenite | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of SH3TC1 mRNA | CTD | PMID:34032870 and PMID:38568856 | Sh3tc1 | Rat | sunitinib | decreases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of SH3TC1 mRNA | CTD | PMID:31533062 | Sh3tc1 | Rat | testosterone | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of SH3TC1 mRNA | CTD | PMID:21592394 | Sh3tc1 | Rat | testosterone | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Testosterone results in increased expression of SH3TC1 mRNA | CTD | PMID:21592394 | Sh3tc1 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SH3TC1 mRNA | CTD | PMID:34492290 | Sh3tc1 | Rat | thiram | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Thiram results in increased expression of SH3TC1 mRNA | CTD | PMID:38568856 | Sh3tc1 | Rat | titanium dioxide | increases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | titanium dioxide results in increased expression of SH3TC1 mRNA | CTD | PMID:23557971 | Sh3tc1 | Rat | triptonide | decreases expression | ISO | Sh3tc1 (Mus musculus) | 6480464 | triptonide results in decreased expression of SH3TC1 mRNA | CTD | PMID:33045310 | Sh3tc1 | Rat | urethane | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Urethane results in increased expression of SH3TC1 mRNA | CTD | PMID:28818685 | Sh3tc1 | Rat | valproic acid | increases methylation | ISO | SH3TC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of SH3TC1 gene | CTD | PMID:29154799 | Sh3tc1 | Rat | valproic acid | increases expression | ISO | SH3TC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of SH3TC1 mRNA | CTD | PMID:28001369 | Sh3tc1 | Rat | zinc atom | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of SH3TC1 mRNA | CTD | PMID:18593933 | Sh3tc1 | Rat | zinc(0) | multiple interactions | ISO | SH3TC1 (Homo sapiens) | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of SH3TC1 mRNA | CTD | PMID:18593933 | |