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Gene: Eif3d (eukaryotic translation initiation factor 3, subunit D) Rattus norvegicus

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Symbol:

Eif3d

Name:

eukaryotic translation initiation factor 3, subunit D

RGD ID:

1303255

Description:

Predicted to enable mRNA cap binding activity and translation initiation factor activity. Predicted to be involved in IRES-dependent viral translational initiation; cytoplasmic translational initiation; and viral translational termination-reinitiation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 3 complex, eIF3m. Predicted to be active in synapse. Orthologous to human EIF3D (eukaryotic translation initiation factor 3 subunit D); PARTICIPATES IN translation initiation pathway; RNA transport pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

eIF-3-zeta; Eif3s7; eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3, subunit 7 (zeta); MGC93918

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	111,420,351 - 111,432,761 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	111,420,351 - 111,432,740 (-)	Ensembl				GRCr8
mRatBN7.2	7	109,539,795 - 109,552,184 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	109,539,356 - 109,552,206 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	111,289,645 - 111,302,037 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	113,513,203 - 113,525,595 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	113,481,200 - 113,493,575 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	119,188,189 - 119,200,578 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	119,188,185 - 119,200,623 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	119,182,951 - 119,195,340 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	115,877,161 - 115,889,550 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	105,880,627 - 105,893,016 (-)	NCBI		Celera
RGSC_v3.1	7	115,911,390 - 115,923,780 (-)	NCBI
Cytogenetic Map	7	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

pre-eclampsia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4,6-tribromophenol (ISO)

2,4-dinitrotoluene (EXP)

2,6-dimethoxyphenol (ISO)

2,6-dinitrotoluene (EXP)

3H-1,2-dithiole-3-thione (ISO)

4,4'-sulfonyldiphenol (ISO)

all-trans-retinoic acid (ISO)

antirheumatic drug (ISO)

atrazine (ISO)

bisphenol A (EXP,ISO)

butan-1-ol (ISO)

cadmium dichloride (EXP)

carbon nanotube (ISO)

chloropicrin (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

chrysene (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

dibutyl phthalate (ISO)

doxorubicin (ISO)

enzyme inhibitor (ISO)

fenthion (ISO)

flutamide (EXP)

furfural (ISO)

gentamycin (EXP)

ivermectin (ISO)

methidathion (ISO)

nitrates (ISO)

paracetamol (ISO)

paraquat (EXP)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

picoxystrobin (ISO)

rotenone (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

sodium chloride (ISO)

sodium dichromate (EXP)

sodium fluoride (ISO)

sunitinib (ISO)

T-2 toxin (EXP)

tamoxifen (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (EXP)

thiram (ISO)

titanium dioxide (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

biological_process (ND)

cap-dependent translational initiation (IEA,ISO,ISS)

cytoplasmic translational initiation (IEA)

formation of cytoplasmic translation initiation complex (IEA,ISO)

IRES-dependent viral translational initiation (IEA,ISO)

translation (IEA)

translational initiation (IBA,IEA,ISO,ISS)

viral translational termination-reinitiation (IEA,ISO)

Cellular Component

cytoplasm (IEA)

cytosol (IEA,ISO)

eukaryotic 43S preinitiation complex (IEA)

eukaryotic 48S preinitiation complex (IEA)

eukaryotic translation initiation factor 3 complex (IBA,IEA,ISO,ISS)

eukaryotic translation initiation factor 3 complex, eIF3m (IEA,ISO)

synapse (IEA,ISO)

Molecular Function

mRNA cap binding (IEA,ISO,ISS)

protein binding (ISO)

RNA binding (IEA,ISO,ISS)

translation initiation factor activity (IBA,IEA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

RNA transport pathway (IEA)

translation initiation pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	The scanning mechanism of eukaryotic translation initiation.	Hinnebusch AG Annu Rev Biochem. 2014;83:779-812. doi: 10.1146/annurev-biochem-060713-035802. Epub 2014 Jan 29.
3.	KEGG Annotation Import Pipeline	Pipeline to import KEGG annotations from KEGG into RGD
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Comprehensive gene review and curation	RGD comprehensive gene curation
7.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:9573242	PMID:17322308	PMID:17581632	PMID:18599441	PMID:19946888	PMID:21347434	PMID:22082260	PMID:22658674	PMID:22681889	PMID:24003236	PMID:24092755	PMID:25849773
PMID:27462815	PMID:28131823

Genomics

Comparative Map Data

Eif3d
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	7	111,420,351 - 111,432,761 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	7	111,420,351 - 111,432,740 (-)	Ensembl				GRCr8
mRatBN7.2	7	109,539,795 - 109,552,184 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	7	109,539,356 - 109,552,206 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	7	111,289,645 - 111,302,037 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	7	113,513,203 - 113,525,595 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	7	113,481,200 - 113,493,575 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	7	119,188,189 - 119,200,578 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	7	119,188,185 - 119,200,623 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	7	119,182,951 - 119,195,340 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	7	115,877,161 - 115,889,550 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	7	105,880,627 - 105,893,016 (-)	NCBI		Celera
RGSC_v3.1	7	115,911,390 - 115,923,780 (-)	NCBI
Cytogenetic Map	7	q34	NCBI

EIF3D
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	22	36,510,855 - 36,529,166 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	22	36,510,850 - 36,529,245 (-)	Ensembl			hg38	GRCh38
GRCh37	22	36,906,902 - 36,925,213 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	22	35,236,843 - 35,255,223 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	22	35,231,397 - 35,249,983	NCBI
Celera	22	20,709,038 - 20,727,412 (-)	NCBI		Celera
Cytogenetic Map	22	q12.3	NCBI
HuRef	22	19,874,728 - 19,893,087 (-)	NCBI		HuRef
CHM1_1	22	36,865,836 - 36,884,218 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	22	36,971,029 - 36,989,335 (-)	NCBI		T2T-CHM13v2.0

Eif3d
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	15	77,843,201 - 77,855,006 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	15	77,843,198 - 77,855,013 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	15	77,958,998 - 77,970,824 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	15	77,958,998 - 77,970,813 (-)	Ensembl			mm10	GRCm38
MGSCv37	15	77,789,428 - 77,801,254 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	15	77,786,256 - 77,798,015 (-)	NCBI		MGSCv36	mm8
Celera	15	79,418,242 - 79,430,068 (-)	NCBI		Celera
Cytogenetic Map	15	E1	NCBI
cM Map	15	36.92	NCBI

Eif3d
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955413	23,092,749 - 23,110,312 (-)	Ensembl
ChiLan1.0	NW_004955413	23,096,440 - 23,110,312 (-)	NCBI	ChiLan1.0	ChiLan1.0

EIF3D
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	23	46,365,301 - 46,383,977 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	22	49,056,546 - 49,075,197 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	22	17,425,745 - 17,444,130 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	22	35,262,541 - 35,282,360 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	22	35,262,541 - 35,282,360 (-)	Ensembl			panPan2	panpan1.1

EIF3D
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	10	27,890,913 - 27,904,887 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	10	27,890,938 - 27,904,886 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	10	27,844,591 - 27,858,525 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	10	28,676,131 - 28,690,129 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	10	28,676,132 - 28,690,138 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	10	28,404,604 - 28,418,627 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	10	28,712,367 - 28,726,367 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	10	28,891,157 - 28,905,180 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Eif3d
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404945	11,245,864 - 11,260,055 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936492	4,255,977 - 4,271,081 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936492	4,256,210 - 4,270,469 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EIF3D
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	5	11,213,312 - 11,229,158 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	5	11,213,312 - 11,229,158 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	5	8,895,436 - 8,911,620 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EIF3D
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	19	19,220,542 - 19,238,534 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	19	19,221,199 - 19,238,468 (-)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666045	106,632,591 - 106,651,239 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Eif3d
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624752	11,197,189 - 11,212,440 (+)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Eif3d
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	10	82,900,650 - 82,902,226 (+)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Eif3d
99 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	46
Count of miRNA genes:	44
Interacting mature miRNAs:	46
Transcripts:	ENSRNOT00000029753
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300179	Kidm5	Kidney mass QTL 5	3.51		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	92388565	119280177	Rat
1331728	Bp214	Blood pressure QTL 214	2.825		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	82111245	123048330	Rat
1331731	Bp216	Blood pressure QTL 216	2.851		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	104186212	135371468	Rat
1357338	Stl17	Serum triglyceride level QTL 17	3.23		blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	7	71621154	114982716	Rat
70159	Bp61	Blood pressure QTL 61		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	73618702	118618702	Rat
631687	Hcas1	Hepatocarcinoma susceptibility QTL 1	3.9	0.001	liver integrity trait (VT:0010547)	liver tumorous lesion volume to total liver volume ratio (CMO:0001082)	7	93302009	131686183	Rat
61397	Bw17	Body weight QTL 17	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	7	95485047	137014596	Rat
631504	Cm27	Cardiac mass QTL 27	3.45		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	7	46307490	127866166	Rat
634322	Bw12	Body weight QTL 12	0		body mass (VT:0001259)	body weight (CMO:0000012)	7	85043242	130043242	Rat
70173	Niddm19	Non-insulin dependent diabetes mellitus QTL 19	4.33	0.00005	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	7	85497398	130497398	Rat
1549899	Stresp8	Stress response QTL 8	4.37	0.0008	stress-related behavior trait (VT:0010451)	defensive burying duration (CMO:0001961)	7	92362341	137014596	Rat
2317052	Aia17	Adjuvant induced arthritis QTL 17	2.13		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	7	83626689	128626689	Rat
1331723	Bw25	Body weight QTL 25	3.348		body mass (VT:0001259)	body weight (CMO:0000012)	7	96700404	111672180	Rat
631529	Tls2	T-lymphoma susceptibility QTL 2	0	0.001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	7	82111382	132099989	Rat
731176	Glom5	Glomerulus QTL 5	2.5	0.0035	kidney glomerulus morphology trait (VT:0005325)	count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)	7	98549867	137014596	Rat
7411607	Foco15	Food consumption QTL 15		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
631201	Panci1	Pancreas inflammation QTL 1	0	0.001	pancreas integrity trait (VT:0010560)	percentage of study population displaying chronic pancreatitis at a point in time (CMO:0001214)	7	73557047	118557047	Rat
634336	Anxrr17	Anxiety related response QTL 17	3.66		locomotor behavior trait (VT:0001392)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	7	1509236	116977875	Rat
1331768	Kidm10	Kidney mass QTL 10	4.62096		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	7	82111245	123048330	Rat
61357	Bp38	Blood pressure QTL 38	1.6	0.052	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	7	40540077	123682549	Rat
2313102	Bmd79	Bone mineral density QTL 79	2.3	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	7	96700404	118618702	Rat
2316947	Rf58	Renal function QTL 58	7.8		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	7	49682832	115766396	Rat
1331748	Bp215	Blood pressure QTL 215	4.043		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	110725024	135371468	Rat
10450862	Kidm55	Kidney mass QTL 55	4.9		kidney mass (VT:0002707)	kidney weight (CMO:0000081)	7	72725037	117725037	Rat
61428	Scl3	Serum cholesterol level QTL 3	3.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	7	100548246	137014596	Rat
1331746	Kidm9	Kidney mass QTL 9	3.934		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	7	82111245	134948181	Rat
10450856	Livw4	Liver weight QTL 4	3.8		liver mass (VT:0003402)	liver weight (CMO:0000092)	7	72725037	117725037	Rat
7411654	Foco25	Food consumption QTL 25	9.3	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	7	77807807	122807807	Rat
2316955	Stl24	Serum triglyceride level QTL 24	7.1		blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	7	49682832	115766396	Rat
10402855	Bp379	Blood pressure QTL 379		0.21	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	78682549	123682549	Rat
2316952	Pur22	Proteinuria QTL 22	5.2		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	7	49682832	115766396	Rat
631540	Bw9	Body weight QTL 9	4.5		body mass (VT:0001259)	body weight (CMO:0000012)	7	71621154	119349044	Rat
1358891	Bp265	Blood pressure QTL 265	2.21		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	7	71827901	136544683	Rat

Markers in Region

RH128317

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	111,420,418 - 111,420,966 (+)	Marker Load Pipeline
mRatBN7.2	7	109,539,862 - 109,540,410 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	119,188,257 - 119,188,804	NCBI	Rnor6.0
Rnor_5.0	7	119,183,019 - 119,183,566	UniSTS	Rnor5.0
RGSC_v3.4	7	115,877,229 - 115,877,776	UniSTS	RGSC3.4
Celera	7	105,880,695 - 105,881,242	UniSTS
RH 3.4 Map	7	811.2	UniSTS
Cytogenetic Map	7	q34	UniSTS

RH125745

Rat Assembly	Chr	Position (strand)	Source	JBrowse
GRCr8	7	111,420,368 - 111,420,961 (+)	Marker Load Pipeline
mRatBN7.2	7	109,539,812 - 109,540,405 (+)	MAPPER	mRatBN7.2
Rnor_6.0	7	119,188,207 - 119,188,799	NCBI	Rnor6.0
Rnor_5.0	7	119,182,969 - 119,183,561	UniSTS	Rnor5.0
RGSC_v3.4	7	115,877,179 - 115,877,771	UniSTS	RGSC3.4
Celera	7	105,880,645 - 105,881,237	UniSTS
Cytogenetic Map	7	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
16	12	67	165	91	90	59	92	59	6	356	192	11	144	81	92	31	17	17

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001004283	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006241938	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC079005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473950	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000007	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000029753 ⟹ ENSRNOP00000032361

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	111,420,351 - 111,432,740 (-)	Ensembl
mRatBN7.2 Ensembl	7	109,539,356 - 109,552,206 (-)	Ensembl
Rnor_6.0 Ensembl	7	119,188,185 - 119,200,623 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104391 ⟹ ENSRNOP00000096030

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	7	111,420,351 - 111,432,740 (-)	Ensembl
mRatBN7.2 Ensembl	7	109,539,356 - 109,552,206 (-)	Ensembl

RefSeq Acc Id:

NM_001004283 ⟹ NP_001004283

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	111,420,351 - 111,432,740 (-)	NCBI
mRatBN7.2	7	109,539,795 - 109,552,184 (-)	NCBI
Rnor_6.0	7	119,188,189 - 119,200,578 (-)	NCBI
Rnor_5.0	7	119,182,951 - 119,195,340 (-)	NCBI
RGSC_v3.4	7	115,877,161 - 115,889,550 (-)	RGD
Celera	7	105,880,627 - 105,893,016 (-)	RGD

Sequence:

show sequence

GTCCCTGCGAGTATCGAGGCTATCGCAGTTTCTTACCCGGGCTATCTGTCGCCATCCGGGCCCG
CGGAGGCCGTTGCAGGTTTTAGAAGATGGCGAAGTTTATGACACCTGTGATCCAGGACAACCCC
TCAGGCTGGGGTCCCTGTGCCGTTCCTGAGCAGTTTCGGGATATGCCCTACCAGCCATTCAGCA
AAGGAGATCGGCTGGGGAAGGTTGCAGACTGGACAGGGGCCACGTACCAGGACAAGAGGTACAC
AAACAAGTATTCCTCTCAGTTCGGTGGGGGAAGTCAGTATGCATATTTCCACGAGGAGGATGAG
ACGAGCTTCCAGCTAGTGGACACAGCGCGTACACAGAAGACGGCCTACCAGCGGAACCGGATGA
GATTCGCACAGCGGAACCTCCGCAGAGACAAAGACCGGCGGAACATGGTGCAGTTCAACCTACA
GACACTGCCCAAAAGTGCCAAGCAGAAAGAGAGAGAACGAATTCGCTTACAGAAAAAATTCCAG
AAGCAATTTGGAGTGAGGCAAAAATGGGACCAGAAGTCACAGAAACCCCGAGACTCCTCGGTTG
AAGTTCGCAGTGACTGGGAGGTGAAGGAGGAGATGGACTTCCCTCAGCTGATGAAGATGCGCTA
CTTGGAGGTGTCAGAGCCTCAAGACATCGAGTGCTGTGGAGCACTGGAGTACTATGACAAAGCC
TTCGACCGCATCACCACGAGGAGTGAGAAGCCTCTGCGGAGCATCAAGCGCATCTTCCACACTG
TCACCACCACAGACGACCCTGTCATCCGGAAGCTGGCAAAAACGCAGGGCAATGTGTTTGCCAC
AGATGCCATCCTGGCCACACTGATGAGCTGCACCCGCTCCGTGTACTCCTGGGACATTGTTGTC
CAGAGGGTCGGATCTAAACTCTTCTTTGACAAGAGGGACAATTCTGACTTTGACCTCCTGACTG
TGAGTGAGACGGCTAACGAGCCCCCTCAAGATGAAGGCAATTCCTTCAACTCACCCCGGAACCT
GGCCATGGAGGCCACCTACATCAACCACAACTTCTCCCAGCAGTGCCTGAGAATGGGGAGAGAG
AGATACAATTTCCCCAACCCAAACCCATTTGTGGAGGATGACATGGATAAGAATGAGATCGCCT
CCGTGGCTTACCGTTACCGGAGGTGGAAGCTTGGAGATGACATTGACCTTATTGTTCGCTGTGA
ACATGATGGCGTCATGACTGGGGCCAACGGGGAAGTGTCCTTCATCAACATCAAGACACTCAAT
GAATGGGACTCCAGGCATTGTAATGGCGTTGACTGGCGTCAGAAGCTGGACTCTCAGCGTGGGG
CTGTCATCGCCACTGAGTTGAAGAACAACAGCTACAAGTTGGCGCGATGGACGTGCTGTGCTTT
GCTGGCTGGCTCTGAGTACTTGAAGCTCGGGTATGTGTCCCGGTACCATGTAAAGGACTCCTCG
CGCCACGTCATCCTGGGCACCCAGCAGTTTAAGCCCAATGAGTTTGCCAGCCAAATCAACCTGA
GTGTGGAGAATGCCTGGGGCATCCTGCGCTGTGTCATTGATATCTGCATGAAGCTGGAGGAGGG
CAAATACCTCATCCTCAAGGACCCCAACAAGCAGGTCATCCGAGTCTACAGCTTGCCTGATGGC
ACCTTCAGCTCTGAGGAGGACGAAGAGGATGAGGAGGAAGAGGAGGAAGAAGAAGAAGAGGAAG
AAACTTAAGTGAGTTGGCCTGGTGCCTGCGTGTGTTAGCACCTAGCTGTGCCTGGGCAGCGTGT
GTCCAGCTCCTGTTCTCTAGCAGAAGAAATAAAATTTAAGTCCTTTTGGTTTCAAAAAAAAAAA
AAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006241938 ⟹ XP_006242000

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	7	111,420,351 - 111,432,761 (-)	NCBI
mRatBN7.2	7	109,539,795 - 109,552,029 (-)	NCBI
Rnor_6.0	7	119,188,189 - 119,200,470 (-)	NCBI
Rnor_5.0	7	119,182,951 - 119,195,340 (-)	NCBI

Sequence:

show sequence

GACCTCGCGAGCCAGCCTGGGCTAGGCATGACTTCGGGGGCTCCCGGAAGAGCCTTCCTTTACG
TCCTCTCCTGTCGTCGGTGCCCCTCCGCTGGGCGGGGCGGGATTCGGCCTCAGGTGGTCCCAGG
CACGACACAGAGTGCAAGACACCGGACATTGTGTGTGGATCCCTCTCCCGACGCTTTGCTGAGG
TTTTAGAAGATGGCGAAGTTTATGACACCTGTGATCCAGGACAACCCCTCAGGCTGGGGTCCCT
GTGCCGTTCCTGAGCAGTTTCGGGATATGCCCTACCAGCCATTCAGCAAAGGAGATCGGCTGGG
GAAGGTTGCAGACTGGACAGGGGCCACGTACCAGGACAAGAGGTACACAAACAAGTATTCCTCT
CAGTTCGGTGGGGGAAGTCAGTATGCATATTTCCACGAGGAGGATGAGACGAGCTTCCAGCTAG
TGGACACAGCGCGTACACAGAAGACGGCCTACCAGCGGAACCGGATGAGATTCGCACAGCGGAA
CCTCCGCAGAGACAAAGACCGGCGGAACATGGTGCAGTTCAACCTACAGACACTGCCCAAAAGT
GCCAAGCAGAAAGAGAGAGAACGAATTCGCTTACAGAAAAAATTCCAGAAGCAATTTGGAGTGA
GGCAAAAATGGGACCAGAAGTCACAGAAACCCCGAGACTCCTCGGTTGAAGTTCGCAGTGACTG
GGAGGTGAAGGAGGAGATGGACTTCCCTCAGCTGATGAAGATGCGCTACTTGGAGGTGTCAGAG
CCTCAAGACATCGAGTGCTGTGGAGCACTGGAGTACTATGACAAAGCCTTCGACCGCATCACCA
CGAGGAGTGAGAAGCCTCTGCGGAGCATCAAGCGCATCTTCCACACTGTCACCACCACAGACGA
CCCTGTCATCCGGAAGCTGGCAAAAACGCAGGGCAATGTGTTTGCCACAGATGCCATCCTGGCC
ACACTGATGAGCTGCACCCGCTCCGTGTACTCCTGGGACATTGTTGTCCAGAGGGTCGGATCTA
AACTCTTCTTTGACAAGAGGGACAATTCTGACTTTGACCTCCTGACTGTGAGTGAGACGGCTAA
CGAGCCCCCTCAAGATGAAGGCAATTCCTTCAACTCACCCCGGAACCTGGCCATGGAGGCCACC
TACATCAACCACAACTTCTCCCAGCAGTGCCTGAGAATGGGGAGAGAGAGATACAATTTCCCCA
ACCCAAACCCATTTGTGGAGGATGACATGGATAAGAATGAGATCGCCTCCGTGGCTTACCGTTA
CCGGAGGTGGAAGCTTGGAGATGACATTGACCTTATTGTTCGCTGTGAACATGATGGCGTCATG
ACTGGGGCCAACGGGGAAGTGTCCTTCATCAACATCAAGACACTCAATGAATGGGACTCCAGGC
ATTGTAATGGCGTTGACTGGCGTCAGAAGCTGGACTCTCAGCGTGGGGCTGTCATCGCCACTGA
GTTGAAGAACAACAGCTACAAGTTGGCGCGATGGACGTGCTGTGCTTTGCTGGCTGGCTCTGAG
TACTTGAAGCTCGGGTATGTGTCCCGGTACCATGTAAAGGACTCCTCGCGCCACGTCATCCTGG
GCACCCAGCAGTTTAAGCCCAATGAGTTTGCCAGCCAAATCAACCTGAGTGTGGAGAATGCCTG
GGGCATCCTGCGCTGTGTCATTGATATCTGCATGAAGCTGGAGGAGGGCAAATACCTCATCCTC
AAGGACCCCAACAAGCAGGTCATCCGAGTCTACAGCTTGCCTGATGGCACCTTCAGCTCTGAGG
AGGACGAAGAGGATGAGGAGGAAGAGGAGGAAGAAGAAGAAGAGGAAGAAACTTAAGTGAGTTG
GCCTGGTGCCTGCGTGTGTTAGCACCTAGCTGTGCCTGGGCAGCGTGTGTCCAGCTCCTGTTCT
CTAGCAGAAGAAATAAAATTTAAGTCCTTTTGGTTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001004283	(Get FASTA)	NCBI Sequence Viewer
	XP_006242000	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH79005	(Get FASTA)	NCBI Sequence Viewer
	EDM15893	(Get FASTA)	NCBI Sequence Viewer
	EDM15894	(Get FASTA)	NCBI Sequence Viewer
	EDM15895	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000032361
	ENSRNOP00000032361.2
GenBank Protein	Q6AYK8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001004283 ⟸ NM_001004283

- UniProtKB:

Q6AYK8 (UniProtKB/Swiss-Prot), A0A8I6GLW5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFG
GGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMVQFNLQTLPKSAKQ
KERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQD
IECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLM
SCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYIN
HNFSQQCLRMGRERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGA
NGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLK
LGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDP
NKQVIRVYSLPDGTFSSEEDEEDEEEEEEEEEEEET

hide sequence

RefSeq Acc Id:	XP_006242000 ⟸ XM_006241938
- Peptide Label:	isoform X1
- UniProtKB:	Q6AYK8 (UniProtKB/Swiss-Prot), A0A8I6GLW5 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAKFMTPVIQDNPSGWGPCAVPEQFRDMPYQPFSKGDRLGKVADWTGATYQDKRYTNKYSSQFG GGSQYAYFHEEDETSFQLVDTARTQKTAYQRNRMRFAQRNLRRDKDRRNMVQFNLQTLPKSAKQ KERERIRLQKKFQKQFGVRQKWDQKSQKPRDSSVEVRSDWEVKEEMDFPQLMKMRYLEVSEPQD IECCGALEYYDKAFDRITTRSEKPLRSIKRIFHTVTTTDDPVIRKLAKTQGNVFATDAILATLM SCTRSVYSWDIVVQRVGSKLFFDKRDNSDFDLLTVSETANEPPQDEGNSFNSPRNLAMEATYIN HNFSQQCLRMGRERYNFPNPNPFVEDDMDKNEIASVAYRYRRWKLGDDIDLIVRCEHDGVMTGA NGEVSFINIKTLNEWDSRHCNGVDWRQKLDSQRGAVIATELKNNSYKLARWTCCALLAGSEYLK LGYVSRYHVKDSSRHVILGTQQFKPNEFASQINLSVENAWGILRCVIDICMKLEEGKYLILKDP NKQVIRVYSLPDGTFSSEEDEEDEEEEEEEEEEEET hide sequence

Ensembl Acc Id:

ENSRNOP00000032361 ⟸ ENSRNOT00000029753

Ensembl Acc Id:

ENSRNOP00000096030 ⟸ ENSRNOT00000104391

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q6AYK8-F1-model_v2	AlphaFold	Q6AYK8	1-548	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13695454

Promoter ID:

EPDNEW_R5979

Type:

initiation region

Name:

Eif3d_1

Description:

eukaryotic translation initiation factor 3, subunit D

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	7	119,200,591 - 119,200,651	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1303255	AgrOrtholog
BioCyc Gene	G2FUF-32849	BioCyc
Ensembl Genes	ENSRNOG00000005804	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000029753	ENTREZGENE
	ENSRNOT00000029753.4	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7113045	IMAGE-MGC_LOAD
InterPro	eIF3d	UniProtKB/Swiss-Prot
KEGG Report	rno:362952	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93918	IMAGE-MGC_LOAD
NCBI Gene	362952	ENTREZGENE
PANTHER	EUKARYOTIC TRANSLATION INITIATION FACTOR 3 SUBUNIT D	UniProtKB/Swiss-Prot
	PTHR12399	UniProtKB/Swiss-Prot
Pfam	eIF-3_zeta	UniProtKB/Swiss-Prot
PhenoGen	Eif3d	PhenoGen
PIRSF	EIF-3_zeta	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000005804	RatGTEx
UniProt	A0A8I6GLW5	ENTREZGENE, UniProtKB/TrEMBL
	EIF3D_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2008-03-04	Eif3d	eukaryotic translation initiation factor 3, subunit D	Eif3s7	eukaryotic translation initiation factor 3, subunit 7 (zeta)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-03-30	Eif3s7	eukaryotic translation initiation factor 3, subunit 7 (zeta)		eukaryotic translation initiation factor 3 subunit 7	Name updated	1299863	APPROVED
2005-09-30	Eif3s7				Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - KEGG (archival)