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Genes search result for Canis lupus familiaris
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63 records found for search term Tox
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RGD IDSymbolNameDescriptionChrStartStopSpeciesAnnotationsMatchType
12310262TOXthymocyte selection associated high mobility group boxENCODES a protein that exhibits chromatin DNA binding (inferred); DNA binding (inferred); INVOLVED IN lymph node development (ortholog); lymphocyte differentiation (ortholog); Peyer's patch development (ortholog); FOUND IN nucleus (inferred); INTERACTS WITH masitinib2995424719841759Dog27symbol , old_gene_namegene, protein-coding, MODEL [RefSeq]
12394764TOX2TOX high mobility group box family member 2ENCODES a protein that exhibits RNA polymerase II-specific DNA-binding transcription factor binding (ortholog); INVOLVED IN female gonad development (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); response to gonadotropin (ortholog); FOUND IN nucleoplasm (inferred);243152332331656361Dog15symbol , namegene, protein-coding, MODEL [RefSeq]
12278448TOX3TOX high mobility group box family member 3ENCODES a protein that exhibits chromatin binding (inferred); DNA binding (inferred); phosphoprotein binding (inferred); INVOLVED IN calcium-mediated signaling (ortholog); positive regulation of DNA-templated transcription (ortholog); ASSOCIATED WITH Breast Neoplasms (ortholog); Cleft Lip with or wi26298170663087519Dog26symbol , namegene, protein-coding, MODEL [RefSeq]
12184978TOX4TOX high mobility group box family member 4ENCODES a protein that exhibits DNA binding (inferred); INVOLVED IN positive regulation of transcription elongation by RNA polymerase II (ortholog); regulation of transcription elongation by RNA polymerase II (ortholog); RNA polymerase II promoter clearance (ortholog); FOUND IN chromatin (ortholog);151851227018528293Dog21symbol , namegene, protein-coding, MODEL [RefSeq]
12234199LOC100684441TOX high mobility group box family member 4-like44347663043478869Dogold_gene_name , namegene, pseudo, MODEL [RefSeq]
12235208LOC100688303TOX high mobility group box family member 4-like3860829236085059Dogold_gene_name , namegene, pseudo, MODEL [RefSeq]
12253149GUCY2Cguanylate cyclase 2CENCODES a protein that exhibits guanylate cyclase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN regulation of cell population proliferation (ortholog); response to toxic substance (ortholog); ASSOCIATE273191555231989748Dog34old_gene_name , descriptiongene, protein-coding, MODEL [RefSeq]
12294892LOC102154920anthrax toxin receptor-like43492898834954358Dognamegene, protein-coding, MODEL [RefSeq]
40918639LOC119881459ras-related C3 botulinum toxin substrate 1ENCODES a protein that exhibits GTP binding (ortholog); Rho GDP-dissociation inhibitor binding (ortholog); INVOLVED IN actin filament organization (ortholog); cell motility (ortholog); neuron migration (ortholog); FOUND IN cytosol (ortholog); lamellipodium (ortholog); membrane (ortholog)Dog52namegene, protein-coding, MODEL [RefSeq]
12345326LOC100684677ras-related C3 botulinum toxin substrate 1-like125299549152997808Dognamegene, pseudo, MODEL [RefSeq]
12130638ANTXR1ANTXR cell adhesion molecule 1ENCODES a protein that exhibits actin filament binding (inferred); collagen binding (inferred); metal ion binding (inferred); INVOLVED IN blood vessel development (ortholog); negative regulation of extracellular matrix assembly (ortholog); positive regulation of metallopeptidase activity (ortholog);106782957368021368Dog41old_gene_namegene, protein-coding, MODEL [RefSeq]
12219630ANTXR2ANTXR cell adhesion molecule 2ENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); INVOLVED IN collagen fibril organization (ortholog); single fertilization (ortholog); uterus development (ortholog); ASSOCIATED WITH ankylosing spondylitis (ortholog); anthrax disease (ortholog); co3241434074302194Dog36old_gene_namegene, protein-coding, MODEL [RefSeq]
12331496ANTXRLANTXR likeENCODES a protein that exhibits metal ion binding (inferred); signaling receptor activity (inferred); FOUND IN membrane (inferred)43488571834916651Dog8old_gene_namegene, protein-coding, MODEL [RefSeq]
12218713ALDH3A2aldehyde dehydrogenase 3 family member A2ENCODES a protein that exhibits 3-chloroallyl aldehyde dehydrogenase activity (ortholog); long-chain fatty aldehyde dehydrogenase (NAD+) activity (ortholog); long-chain-alcohol oxidase activity (ortholog); INVOLVED IN central nervous system development (ortholog); epidermis development (ortholog); f54051576840641377Dog53old_gene_namegene, protein-coding, MODEL [RefSeq]
12305715SLC47A1solute carrier family 47 member 1ENCODES a protein that exhibits amide transmembrane transporter activity (ortholog); xenobiotic transmembrane transporter activity (ortholog); INVOLVED IN monoatomic cation transmembrane transport (ortholog); monoatomic cation transport (ortholog); organic cation transport (ortholog); PARTICIPATES I54064342040679130Dog50old_gene_namegene, protein-coding, MODEL [RefSeq]
12342201SLC47A2solute carrier family 47 member 2ENCODES a protein that exhibits antiporter activity (inferred); polyspecific organic cation:proton antiporter activity (inferred); transmembrane transporter activity (inferred); INVOLVED IN organic cation transport (inferred); proton transmembrane transport (inferred); transmembrane transport (infer54049130640515430Dog19old_gene_namegene, protein-coding, MODEL [RefSeq]
12420176RAC1Rac family small GTPase 1ENCODES a protein that exhibits ATPase binding (ortholog); enzyme binding (ortholog); GTP binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); actin filament organization (ortholog); actin filament polymerization (ortholog); PARTICIPATES IN Arf family mediated signaling pathwa61172625911758532Dog251old_gene_namegene, protein-coding, PROVISIONAL [RefSeq]
12399152RAC2Rac family small GTPase 2ENCODES a protein that exhibits G protein activity (inferred); GTP binding (inferred); GTPase activity (inferred); INVOLVED IN actin cytoskeleton organization (ortholog); bone resorption (ortholog); cell projection assembly (ortholog); ASSOCIATED WITH acute myeloid leukemia (ortholog); Chronic Perio102729559727311864Dog78old_gene_namegene, protein-coding, MODEL [RefSeq]
12184933RAC3Rac family small GTPase 3ENCODES a protein that exhibits calcium-dependent protein binding (inferred); G protein activity (inferred); GTP binding (inferred); INVOLVED IN cerebral cortex GABAergic interneuron development (ortholog); homeostasis of number of cells within a tissue (ortholog); neuromuscular process (ortholog); 9293260295990Dog61old_gene_namegene, protein-coding, MODEL [RefSeq]
12136668TMEM181transmembrane protein 181ENCODES a protein that exhibits toxic substance binding (inferred); FOUND IN membrane (inferred)14796924748058207Dog4descriptiongene, protein-coding, MODEL [RefSeq]
12063362ABCB1ATP binding cassette subfamily B member 1ENCODES a protein that exhibits transmembrane transporter activity (ortholog); INVOLVED IN adult heart development (ortholog); aldosterone secretion (ortholog); cardiac muscle cell differentiation (ortholog); PARTICIPATES IN axitinib pharmacokinetics pathway; clopidogrel pharmacodynamics pathway; cl141364489113852829Dog331descriptiongene, protein-coding, VALIDATED [RefSeq]
12063585ABTB2ankyrin repeat and BTB domain containing 2ENCODES a protein that exhibits protein heterodimerization activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); FOUND IN nucleoplasm (inferred)183348392533651165Dog4descriptiongene, protein-coding, MODEL [RefSeq]
12299462ADALadenosine deaminase likeENCODES a protein that exhibits deaminase activity (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN nucleotide metabolic process (inferred); toxic metabolite repair (inferred)301019101910214089Dog11descriptiongene, protein-coding, MODEL [RefSeq]
12059853AQP10aquaporin 10ENCODES a protein that exhibits channel activity (inferred); glycerol channel activity (inferred); water channel activity (inferred); INVOLVED IN glycerol transmembrane transport (inferred); protein homotetramerization (inferred); response to toxic substance (in74296104142964053Dog25descriptiongene, protein-coding, MODEL [RefSeq]
12277376ARHGAP33Rho GTPase activating protein 33ENCODES a protein that exhibits GTPase activator activity (inferred); phosphatidylinositol binding (inferred); protein kinase binding (inferred); INVOLVED IN regulation of dendritic spine morphogenesis (ortholog); response to toxic substance (ortholog); ASSOCIAT1116851341116864696Dog28descriptiongene, protein-coding, MODEL [RefSeq]
12391639AS3MTarsenite methyltransferaseENCODES a protein that exhibits arsenite methyltransferase activity (ortholog); INVOLVED IN arsonoacetate metabolic process (ortholog); response to arsenic-containing substance (ortholog); toxin metabolic process (ortholog); PARTICIPATES IN homocysteine metaboli281533414115350749Dog28descriptiongene, protein-coding, MODEL [RefSeq]
12157586ASS1argininosuccinate synthase 1ENCODES a protein that exhibits argininosuccinate synthase activity (ortholog); toxic substance binding (ortholog); INVOLVED IN acute-phase response (ortholog); argininosuccinate metabolic process (ortholog); cellular response to amine stimulus (ortholog); PARTI95342522853478007Dog128descriptiongene, protein-coding, MODEL [RefSeq]
12407493BLMHbleomycin hydrolaseENCODES a protein that exhibits aminopeptidase activity (inferred); cysteine-type aminopeptidase activity (inferred); cysteine-type endopeptidase activity (inferred); INVOLVED IN response to toxic substance (ortholog); response to xenobiotic stimulus (ortholog);94427166244319814Dog29descriptiongene, protein-coding, MODEL [RefSeq]
12139493CDH13cadherin 13ENCODES a protein that exhibits adiponectin binding (inferred); cadherin binding (inferred); calcium ion binding (inferred); INVOLVED IN cellular response to toxic substance (ortholog); cellular response to xenobiotic stimulus (ortholog); ASSOCIATED WITH ampheta56849115669586119Dog86descriptiongene, protein-coding, MODEL [RefSeq]
12202613CRISPLD2cysteine rich secretory protein LCCL domain containing 2ENCODES a protein that exhibits glycosaminoglycan binding (inferred); heparin binding (inferred); INVOLVED IN extracellular matrix organization (ortholog); lung development (ortholog); ASSOCIATED WITH liver disease (ortholog); lung disease (ortholog); toxic ence56764322567707438Dog15descriptiongene, protein-coding, MODEL [RefSeq]
12164501CYP2F1cytochrome P450 family 2 subfamily F member 1ENCODES a protein that exhibits monooxygenase activity (ortholog); INVOLVED IN naphthalene catabolic process (ortholog); response to toxic substance (ortholog); trichloroethylene metabolic process (ortholog); ASSOCIATED WITH autism spectrum disorder (ortholog); 1112973776112986419Dog22descriptiongene, protein-coding, MODEL [RefSeq]
12272054DHX15DEAH-box helicase 15ENCODES a protein that exhibits ATP binding (inferred); double-stranded RNA binding (inferred); helicase activity (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN ribosome biogenesis pathway; splice38554994685609598Dog46descriptiongene, protein-coding, MODEL [RefSeq]
12178935GFERgrowth factor, augmenter of liver regenerationENCODES a protein that exhibits flavin-dependent sulfhydryl oxidase activity (ortholog); INVOLVED IN cellular response to actinomycin D (ortholog); cellular response to lipopolysaccharide (ortholog); cellular response to toxic substance (ortholog); PARTICIPATES 63894892738951300Dog57descriptiongene, protein-coding, MODEL [RefSeq]
12107454GLYATglycine-N-acyltransferaseENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to tox183768907637715614Dog21descriptiongene, protein-coding, MODEL [RefSeq]
12384201GSTA4glutathione S-transferase alpha 4ENCODES a protein that exhibits identical protein binding (ortholog); protein homodimerization activity (ortholog); toxic substance binding (ortholog); INVOLVED IN cellular response to lithium ion (ortholog); response to herbicide (ortholog); response to nicotin122042672420443200Dog34descriptiongene, protein-coding, VALIDATED [RefSeq]
12067734IDO1indoleamine 2,3-dioxygenase 1ENCODES a protein that exhibits amino acid binding (ortholog); indoleamine 2,3-dioxygenase activity (ortholog); oxygen binding (ortholog); INVOLVED IN inflammatory response (ortholog); kynurenic acid biosynthetic process (ortholog); L-tryptophan catabolic process to L-kynurenine (ortholog); PARTICIP162539175925407161Dog85descriptiongene, protein-coding, MODEL [RefSeq]
12078940IL20RAinterleukin 20 receptor subunit alphaENCODES a protein that exhibits interleukin-20 binding (inferred); INVOLVED IN cytokine-mediated signaling pathway (ortholog); positive regulation of intrinsic apoptotic signaling pathway (ortholog); regulation of bone resorption (ortholog); ASSOCIATED WITH Spontaneous Abortions (ortholog); tox12950658229545882Dog12descriptiongene, protein-coding, MODEL [RefSeq]
12132843IL20RBinterleukin 20 receptor subunit betaENCODES a protein that exhibits interleukin-20 binding (inferred); INVOLVED IN homeostasis of number of cells within a tissue (ortholog); immune response-inhibiting signal transduction (ortholog); inflammatory response to antigenic stimulus (ortholog); ASSOCIATED WITH tox233338405733421619Dog18descriptiongene, protein-coding, MODEL [RefSeq]
12167679IL21interleukin 21ENCODES a protein that exhibits cytokine activity (inferred); cytokine receptor binding (inferred); interleukin-2 receptor binding (inferred); INVOLVED IN cellular response to virus (ortholog); germinal center B cell differentiation (ortholog); positive regulation of B cell proliferation (ortholog);191764183317651275Dog86descriptiongene, protein-coding, PROVISIONAL [RefSeq]
12246608IL23Ainterleukin 23 subunit alphaENCODES a protein that exhibits cytokine activity (inferred); interleukin-23 receptor binding (inferred); INVOLVED IN positive regulation of receptor signaling pathway via JAK-STAT (ortholog); positive regulation of transcription by RNA polymerase II (ortholog); T cell proliferation (ortholog); PART10635384640715Dog88descriptiongene, protein-coding, MODEL [RefSeq]
12343649IL2RBinterleukin 2 receptor subunit betaENCODES a protein that exhibits interleukin-2 binding (ortholog); interleukin-2 receptor activity (ortholog); INVOLVED IN cytokine-mediated signaling pathway (ortholog); negative regulation of apoptotic process (ortholog); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pat102737079727388775Dog55descriptiongene, protein-coding, VALIDATED [RefSeq]
12155481LDLRlow density lipoprotein receptorENCODES a protein that exhibits low-density lipoprotein particle receptor activity (ortholog); molecular adaptor activity (ortholog); INVOLVED IN artery development (ortholog); cholesterol homeostasis (ortholog); cholesterol metabolic process (ortholog); PARTICIPATES IN atherosclerosis pathway; ASSO205011517550152443Dog300descriptiongene, protein-coding, MODEL [RefSeq]
12336361LOC106559796uncharacterized LOC106559796ENCODES a protein that exhibits RNA nuclease activity (ortholog); INVOLVED IN antibacterial humoral response (ortholog); antimicrobial humoral immune response mediated by antimicrobial peptide (ortholog); defense response to Gram-negative bacterium (ortholog); ASSOCIATED WITH liver disease (ortholog151802437518025871Dog15descriptiongene, protein-coding, MODEL [RefSeq]
12395171LOC476047solute carrier family 22 member 9ENCODES a protein that exhibits secondary active transmembrane transporter activity (ortholog); short-chain fatty acid transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN hormone transport (ortholog); o185350410253546354Dog15descriptiongene, protein-coding, MODEL [RefSeq]
12337847LOC482436L-amino-acid oxidase-likeENCODES a protein that exhibits L-amino-acid oxidase activity (inferred); oxidoreductase activity (inferred); toxin activity (inferred); INVOLVED IN defense response to bacterium (inferred); modulation of process of another organism (inferred); FOUND IN extracel15335458342935Dog12descriptiongene, protein-coding, MODEL [RefSeq]
12365286LOC483462glycine N-phenylacetyltransferase-likeENCODES a protein that exhibits acyltransferase activity (inferred); glycine N-acyltransferase activity (inferred); glycine N-benzoyltransferase activity (inferred); INVOLVED IN benzoyl-CoA metabolic process (inferred); glycine metabolic process (inferred); response to tox183762648837676184Dog19descriptiongene, protein-coding, MODEL [RefSeq]
12282410LOC611908phosphorylated adapter RNA export protein-likeENCODES a protein that exhibits toxic substance binding (ortholog); INVOLVED IN snRNA export from nucleus (ortholog); FOUND IN neuronal cell body (ortholog)44915540849157318Dog8descriptiongene, protein-coding, MODEL [RefSeq]
12365689LRP5LDL receptor related protein 5ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN amino acid transport (ortholog); anatomical structure regression (ortholog); anterior/posterior pattern specification (ortholog); PARTICIPATES IN altered Wnt signali184943949449555375Dog157descriptiongene, protein-coding, MODEL [RefSeq]
12139753LRP6LDL receptor related protein 6ENCODES a protein that exhibits toxin transmembrane transporter activity (ortholog); INVOLVED IN anterior/posterior pattern specification (ortholog); axis elongation (ortholog); axis elongation involved in somitogenesis (ortholog); PARTICIPATES IN Wnt signaling,273400333434166334Dog226descriptiongene, protein-coding, MODEL [RefSeq]
12428607NEFMneurofilament medium chainENCODES a protein that exhibits protein-containing complex binding (ortholog); signaling receptor binding (ortholog); toxic substance binding (ortholog); INVOLVED IN axo-dendritic transport (ortholog); axon regeneration (ortholog); cellular response to estradiol253249351732498615Dog64descriptiongene, protein-coding, MODEL [RefSeq]
12162165NR4A2nuclear receptor subfamily 4 group A member 2ENCODES a protein that exhibits DNA binding (inferred); DNA-binding transcription activator activity, RNA polymerase II-specific (inferred); DNA-binding transcription factor activity (inferred); INVOLVED IN adult locomotory behavior (ortholog); cellular response to oxidative stress (ortholog); centr3625462372554559Dog112descriptiongene, protein-coding, MODEL [RefSeq]
12104128P2RX1purinergic receptor P2X 1ENCODES a protein that exhibits ATP binding (ortholog); extracellularly ATP-gated monoatomic cation channel activity (ortholog); identical protein binding (ortholog); INVOLVED IN ceramide biosynthetic process (ortholog); insemination (ortholog); monoatomic cation transmembrane transport (ortholog); 94767417547694358Dog69descriptiongene, protein-coding, MODEL [RefSeq]
12257533PPP1R9Aprotein phosphatase 1 regulatory subunit 9AENCODES a protein that exhibits GTPase binding (ortholog); identical protein binding (ortholog); protein domain specific binding (ortholog); INVOLVED IN actin filament organization (ortholog); calcium-mediated signaling (ortholog); cellular response to toxic sub142025179120563315Dog76descriptiongene, protein-coding, MODEL [RefSeq]
12079637PTPN13protein tyrosine phosphatase non-receptor type 13ENCODES a protein that exhibits hydrolase activity (inferred); phosphatidylinositol 3-kinase regulatory subunit binding (inferred); phosphoprotein phosphatase activity (inferred); INVOLVED IN cellular response to toxic substance (ortholog); negative regulation o321012544710328764Dog76descriptiongene, protein-coding, MODEL [RefSeq]
12421811RORCRAR related orphan receptor CENCODES a protein that exhibits DNA-binding transcription factor activity, RNA polymerase II-specific (ortholog); transcription coactivator binding (ortholog); INVOLVED IN adipose tissue development (ortholog); alpha-beta T cell differentiation (ortholog); cell differentiation (ortholog); ASSOCIATED176082149860842485Dog80descriptiongene, protein-coding, MODEL [RefSeq]
12118936SLC17A2solute carrier family 17 member 2ENCODES a protein that exhibits efflux transmembrane transporter activity (inferred); symporter activity (inferred); toxin transmembrane transporter activity (inferred); INVOLVED IN monoatomic anion transmembrane transport (inferred); monoatomic ion transport (i352383911323919789Dog33descriptiongene, protein-coding, MODEL [RefSeq]
12428989SLC17A3solute carrier family 17 member 3ENCODES a protein that exhibits efflux transmembrane transporter activity (inferred); symporter activity (inferred); toxin transmembrane transporter activity (inferred); INVOLVED IN monoatomic anion transmembrane transport (inferred); monoatomic ion transport (i352379228123831893Dog33descriptiongene, protein-coding, MODEL [RefSeq]
12398987SLC22A3solute carrier family 22 member 3ENCODES a protein that exhibits dopamine:sodium symporter activity (ortholog); spermidine transmembrane transporter activity (ortholog); toxin transmembrane transporter activity (ortholog); INVOLVED IN dopamine transport (ortholog); histamine transport (ortholog14940794949496627Dog80descriptiongene, protein-coding, MODEL [RefSeq]
12273346SLC6A14solute carrier family 6 member 14ENCODES a protein that exhibits aromatic amino acid transmembrane transporter activity (ortholog); INVOLVED IN amino acid import across plasma membrane (ortholog); response to toxic substance (ortholog); ASSOCIATED WITH Acidoses (ortholog); celiac disease (orthoX8893917688965093Dog29descriptiongene, protein-coding, MODEL [RefSeq]
12252825SRSF9serine and arginine rich splicing factor 9ENCODES a protein that exhibits nucleic acid binding (inferred); protein domain specific binding (inferred); RNA binding (inferred); INVOLVED IN response to alkaloid (ortholog); response to toxic substance (ortholog); PARTICIPATES IN spliceosome pathway; ASSOCIA261636327516369699Dog27descriptiongene, protein-coding, MODEL [RefSeq]
12431997ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN cellular response to heat (ortholog); positive regulation of cell population proliferation (ortholog); ASSOCIATED WITH liver disease (ortholog); toxic encephalopathy (ortholog); F272487910325027014Dog18descriptiongene, protein-coding, MODEL [RefSeq]
12365509STING1stimulator of interferon response cGAMP interactor 1ENCODES a protein that exhibits 2',3'-cyclic GMP-AMP binding (inferred); cyclic-di-GMP binding (inferred); identical protein binding (inferred); INVOLVED IN cellular response to interferon-beta (ortholog); defense response to virus (ortholog); positive regulation of transcription by RNA polymerase I23478394734792204Dog135descriptiongene, protein-coding, VALIDATED [RefSeq]
12298741XRCC1X-ray repair cross complementing 1ENCODES a protein that exhibits 3' overhang single-stranded DNA endodeoxyribonuclease activity (inferred); ADP-D-ribose modification-dependent protein binding (inferred); damaged DNA binding (inferred); INVOLVED IN base-excision repair (ortholog); DNA damage response (ortholog); DNA repair (ortholog1111548719111571816Dog201descriptiongene, protein-coding, VALIDATED [RefSeq]