ST8SIA1 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1) - Rat Genome Database

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Gene: ST8SIA1 (ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1) Canis lupus familiaris
Analyze
Symbol: ST8SIA1
Name: ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
RGD ID: 12431997
Description: ENCODES a protein that exhibits sialyltransferase activity (ortholog); INVOLVED IN cell population proliferation (ortholog); cellular response to heat (ortholog); epithelial cell proliferation (ortholog); ASSOCIATED WITH genetic disease (ortholog); liver disease (ortholog); toxic encephalopathy (ortholog); FOUND IN Golgi apparatus (inferred); Golgi membrane (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: alpha-N-acetylneuraminide alpha-2,8-sialyltransferase
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: CanFam3.1 - Dog CanFam3.1 Assembly
Position:
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12724,879,103 - 25,027,014 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2724,879,380 - 25,023,618 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2721,333,527 - 21,483,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02725,096,491 - 25,246,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,096,525 - 25,238,358 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12724,894,560 - 25,045,533 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02724,918,605 - 25,068,657 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02721,502,984 - 21,653,212 (-)NCBIUU_Cfam_GSD_1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ST8SIA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12724,879,103 - 25,027,014 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2724,879,380 - 25,023,618 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2721,333,527 - 21,483,378 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02725,096,491 - 25,246,504 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2725,096,525 - 25,238,358 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12724,894,560 - 25,045,533 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02724,918,605 - 25,068,657 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02721,502,984 - 21,653,212 (-)NCBIUU_Cfam_GSD_1.0
ST8SIA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381222,193,391 - 22,334,707 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1222,063,773 - 22,437,041 (-)EnsemblGRCh38hg38GRCh38
GRCh371222,346,325 - 22,487,641 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361222,245,200 - 22,378,915 (-)NCBINCBI36Build 36hg18NCBI36
Celera1227,500,769 - 27,642,080 (-)NCBICelera
Cytogenetic Map12p12.1NCBI
HuRef1222,119,372 - 22,260,647 (-)NCBIHuRef
CHM1_11222,311,335 - 22,452,993 (-)NCBICHM1_1
T2T-CHM13v2.01222,071,418 - 22,212,735 (-)NCBIT2T-CHM13v2.0
St8sia1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396142,767,267 - 142,935,247 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6142,767,271 - 142,910,178 (-)EnsemblGRCm39 Ensembl
GRCm386142,821,541 - 142,989,528 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6142,821,545 - 142,964,452 (-)EnsemblGRCm38mm10GRCm38
MGSCv376142,770,061 - 142,912,972 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366142,778,763 - 142,921,674 (-)NCBIMGSCv36mm8
Celera6145,883,284 - 146,020,842 (-)NCBICelera
Cytogenetic Map6G3NCBI
cM Map674.78NCBI
St8sia1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84177,513,966 - 177,651,553 (-)NCBIGRCr8
mRatBN7.24175,782,989 - 175,921,338 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4175,789,947 - 175,920,708 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4182,084,919 - 182,215,399 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04177,869,195 - 177,999,668 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04176,489,766 - 176,620,240 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04177,065,266 - 177,195,942 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4177,065,168 - 177,196,180 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04241,274,072 - 241,403,150 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44180,722,382 - 180,852,639 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14180,967,505 - 181,097,763 (-)NCBI
Celera4164,320,658 - 164,451,184 (-)NCBICelera
Cytogenetic Map4q44NCBI
St8sia1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541317,672,460 - 17,805,623 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541317,667,434 - 17,810,671 (-)NCBIChiLan1.0ChiLan1.0
ST8SIA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21074,434,500 - 74,618,644 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11274,430,888 - 74,615,043 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01263,972,127 - 64,112,083 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11266,578,598 - 66,712,240 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1266,578,949 - 66,712,240 (+)Ensemblpanpan1.1panPan2
St8sia1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494586,748,403 - 86,880,894 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365484,671,284 - 4,796,426 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365484,671,257 - 4,797,917 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ST8SIA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl551,211,336 - 51,358,144 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1551,211,312 - 51,364,226 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
ST8SIA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11122,035,111 - 22,172,244 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1122,035,661 - 22,170,548 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606912,973,699 - 13,108,791 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
St8sia1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475216,483,378 - 16,633,776 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475216,483,168 - 16,633,938 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ST8SIA1
1885 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system reproductive system respiratory system adipose tissue
High
Medium 8
Low 5 4 19 4 6 4 6 12 10 6
Below cutoff 1 3 2 2 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSCAFT00000018817   ⟹   ENSCAFP00000017436
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2724,879,380 - 25,018,872 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000064040   ⟹   ENSCAFP00000049854
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2724,879,380 - 25,023,618 (+)Ensembl
RefSeq Acc Id: ENSCAFT00000087702   ⟹   ENSCAFP00000056605
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.1 Ensembl2724,879,380 - 25,018,872 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845025420   ⟹   ENSCAFP00845020012
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2725,096,525 - 25,238,358 (+)Ensembl
RefSeq Acc Id: ENSCAFT00845025477   ⟹   ENSCAFP00845020061
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.0 Ensembl2725,096,525 - 25,238,358 (+)Ensembl
RefSeq Acc Id: XM_038438776   ⟹   XP_038294704
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
ROS_Cfam_1.02725,096,491 - 25,246,504 (+)NCBI
RefSeq Acc Id: XM_038513448   ⟹   XP_038369376
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UMICH_Zoey_3.12724,894,560 - 25,045,533 (+)NCBI
RefSeq Acc Id: XM_038577027   ⟹   XP_038432955
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UU_Cfam_GSD_1.02721,502,984 - 21,653,212 (-)NCBI
RefSeq Acc Id: XM_038641247   ⟹   XP_038497175
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
UNSW_CanFamBas_1.02724,918,605 - 25,068,657 (+)NCBI
RefSeq Acc Id: XM_534865   ⟹   XP_534865
Type: CODING
Position:
Dog AssemblyChrPosition (strand)Source
CanFam3.12724,879,103 - 25,027,014 (+)NCBI
Dog10K_Boxer_Tasha2721,333,527 - 21,483,378 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: XP_534865   ⟸   XM_534865
- UniProtKB: A0A8C0TU42 (UniProtKB/TrEMBL),   A0A8I3S0P4 (UniProtKB/TrEMBL),   A0A8C0PDP8 (UniProtKB/TrEMBL),   A0A8I3RY01 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSCAFP00000049854   ⟸   ENSCAFT00000064040
RefSeq Acc Id: ENSCAFP00000017436   ⟸   ENSCAFT00000018817
RefSeq Acc Id: ENSCAFP00000056605   ⟸   ENSCAFT00000087702
RefSeq Acc Id: XP_038369376   ⟸   XM_038513448
RefSeq Acc Id: XP_038497175   ⟸   XM_038641247
RefSeq Acc Id: XP_038294704   ⟸   XM_038438776
- UniProtKB: A0A8C0TU42 (UniProtKB/TrEMBL),   A0A8I3S0P4 (UniProtKB/TrEMBL),   A0A8C0PDP8 (UniProtKB/TrEMBL),   A0A8I3RY01 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038432955   ⟸   XM_038577027
- UniProtKB: A0A8C0PDP8 (UniProtKB/TrEMBL),   A0A8C0TU42 (UniProtKB/TrEMBL),   A0A8I3RY01 (UniProtKB/TrEMBL),   A0A8I3S0P4 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSCAFP00845020061   ⟸   ENSCAFT00845025477
RefSeq Acc Id: ENSCAFP00845020012   ⟸   ENSCAFT00845025420


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCAFG00000011838 Ensembl, UniProtKB/TrEMBL
  ENSCAFG00030021951 UniProtKB/TrEMBL
  ENSCAFG00040024377 UniProtKB/TrEMBL
  ENSCAFG00845014219 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSCAFT00000018817.4 UniProtKB/TrEMBL
  ENSCAFT00000064040.2 UniProtKB/TrEMBL
  ENSCAFT00000087702.2 UniProtKB/TrEMBL
  ENSCAFT00030040252.1 UniProtKB/TrEMBL
  ENSCAFT00030040281.1 UniProtKB/TrEMBL
  ENSCAFT00030040304.1 UniProtKB/TrEMBL
  ENSCAFT00040045415.1 UniProtKB/TrEMBL
  ENSCAFT00040045441.1 UniProtKB/TrEMBL
  ENSCAFT00845025420 ENTREZGENE
  ENSCAFT00845025420.1 UniProtKB/TrEMBL
  ENSCAFT00845025477.1 UniProtKB/TrEMBL
Gene3D-CATH 3.90.1480.20 UniProtKB/TrEMBL
InterPro Glyco_trans_29 UniProtKB/TrEMBL
  GT29-like_sf UniProtKB/TrEMBL
  Sialyl_trans UniProtKB/TrEMBL
KEGG Report cfa:477672 UniProtKB/TrEMBL
NCBI Gene ST8SIA1 ENTREZGENE
PANTHER ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/TrEMBL
  ALPHA-N-ACETYLNEURAMINIDE ALPHA-2,8-SIALYLTRANSFERASE UniProtKB/TrEMBL
Pfam Glyco_transf_29 UniProtKB/TrEMBL
PIRSF Sialyl_trans UniProtKB/TrEMBL
UniProt A0A8C0PDP8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8C0PHI8_CANLF UniProtKB/TrEMBL
  A0A8C0TU13_CANLF UniProtKB/TrEMBL
  A0A8C0TU42 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3RY01 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I3S0P4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8P0T2J5_CANLF UniProtKB/TrEMBL
VGNC ID VGNC:46864 ENTREZGENE