| 1320303 | Car1 | carbonic anhydrase 1 | Predicted to enable arylesterase activity; carbonate dehydratase activity; and cyanamide hydratase activity. Predicted to be active in cytoplasm. Is expressed in several structures, including alimentary system; limb; nervous system; sensory organ; and skeleton. Used to study major depressive disorde r. Human ortholog(s) of this gene implicated in autoimmune disease (multiple) and viral hepatitis. Orthologous to human CA1 (carbonic anhydrase 1). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 14831274 | 14873425 | Mouse | 188 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 12170546 | CAR1 | syncytin-Car1 | Many different endogenous retrovirus families are expressed in normal placental tissue at high levels, suggesting that endogenous retroviruses are functionally important in reproduction. This gene is part of a dog endogenous retrovirus provirus that has inactivating mutations in the gag and pol gene s. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product plays a major role in placental development and trophoblast fusion. The protein has the characteristics of a typical retroviral envelope protein, including a cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. [provided by RefSeq, Apr 2015] | 3 | 83844415 | 83845836 | Dog | 1 | symbol , old_gene_name , name | gene, protein-coding, REVIEWED [RefSeq] |
| 14369351 | CAR1 | | | | | | Yeast | | symbol | gene, null |
| 1309780 | Ca1 | carbonic anhydrase 1 | ENCODES a protein that exhibits arylesterase activity (ortholog); carbonate dehydratase activity (ortholog); cyanamide hydratase activity (ortholog); INVOLVED IN response to fructose; PARTICIPATES IN cimetidine pharmacodynamics pathway; esomeprazole pharmacodynamics pathway; famotidine pharmacodynam ics pathway; ASSOCIATED WITH colitis; adenocarcinoma (ortholog); chronic pancreatitis (ortholog); FOUND IN cytoplasm (inferred); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene | 2 | 88550681 | 88593454 | Rat | 185 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1320302 | CA1 | carbonic anhydrase 1 | Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrosp inal fluid, saliva and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This CA1 gene is closely linked to the CA2 and CA3 genes on chromosome 8. It encodes a cytosolic protein that is found at the highest level in erythrocytes. Allelic variants of this gene have been described in some populations. Alternative splicing and the use of alternative promoters results in multiple transcript variants. [provided by RefSeq, Nov 2016] | 8 | 85327608 | 85378113 | Human | 188 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 619794 | Cxadr | CXADR cell adhesion molecule | ENCODES a protein that exhibits beta-catenin binding (ortholog); cell adhesion molecule binding (ortholog); connexin binding (ortholog); INVOLVED IN actin cytoskeleton organization (ortholog); AV node cell to bundle of His cell communication (ortholog); AV node cell-bundle of His cell adhesion invol ved in cell communication (ortholog); PARTICIPATES IN myocarditis pathway; ASSOCIATED WITH Experimental Liver Cirrhosis (ortholog); FOUND IN bicellular tight junction; neuron projection; acrosomal vesicle (ortholog); INTERACTS WITH 1-naphthyl isothiocyanate; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine | 11 | 30469778 | 30516990 | Rat | 236 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1344163 | NR1I3 | nuclear receptor subfamily 1 group I member 3 | This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target genes involved in drug metabolism and bilirubi n clearance, such as cytochrome P450 family members. Unlike most nuclear receptors, this transcriptional regulator is constitutively active in the absence of ligand but is regulated by both agonists and inverse agonists. Ligand binding results in translocation of this protein to the nucleus, where it activates or represses target gene transcription. These ligands include bilirubin, a variety of foreign compounds, steroid hormones, and prescription drugs. In addition to drug metabolism, the CAR protein is also reported to regulate genes involved in glucose metabolism, lipid metabolism, cell proliferation, and circadian clock regulation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2020] | 1 | 161229669 | 161238203 | Human | 976 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 620180 | Slc40a1 | solute carrier family 40 member 1 | ENCODES a protein that exhibits ferrous iron transmembrane transporter activity (ortholog); identical protein binding (ortholog); iron ion transmembrane transporter activity (ortholog); INVOLVED IN endothelium development (ortholog); intracellular iron ion homeostasis (ortholog); iron ion export acr oss plasma membrane (ortholog); PARTICIPATES IN iron efflux pathway; ASSOCIATED WITH aceruloplasminemia (ortholog); anemia (ortholog); autistic disorder (ortholog); FOUND IN basolateral plasma membrane (ortholog); plasma membrane (ortholog); synaptic vesicle (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine | 9 | 55525457 | 55633463 | Rat | 428 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736538 | CD247 | CD247 molecule | The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several int racellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] | 1 | 167430640 | 167518529 | Human | 238 | old_gene_name | gene, protein-coding, REVIEWED [RefSeq] |
| 1558371 | Car10 | carbonic anhydrase 10 | Predicted to enable hydro-lyase activity. Is expressed in several structures, including cardiovascular system; central nervous system; foregut; integumental system; and respiratory system. Orthologous to human CA10 (carbonic anhydrase 10). [provided by Alliance of Genome Resources, Jul 2025] | 11 | 92988807 | 93492577 | Mouse | 44 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 2322930 | Car10 | carbonic anhydrase 10 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); ASSOCIATED WITH asthma (ortholog); INTERACTS WITH atrazine; DDT; glyphosate | 10 | 78551067 | 79053421 | Rat | 44 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1550538 | Car11 | carbonic anhydrase 11 | Predicted to enable hydro-lyase activity. Located in basolateral plasma membrane. Is expressed in several structures, including alimentary system; ear; eye; genitourinary system; and nervous system. Orthologous to human CA11 (carbonic anhydrase 11). [provided by Alliance of Genome Resources, Jul 202 5] | 7 | 45348537 | 45354106 | Mouse | 87 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1315328 | Car12 | carbonic anhydrase 12 | This gene encodes a membrane-bound member of the alpha carbonic anhydrase family of enzymes that catalyze the reversible hydration of carbon dioxide to bicarbonate. These proteins participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorpti on, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015] | 9 | 66619026 | 66674127 | Mouse | 187 | symbol , PhenoGen | gene, protein-coding, REVIEWED [RefSeq] |
| 1322169 | Car13 | carbonic anhydrase 13 | Enables carbonate dehydratase activity. Located in cytosol; intracellular membrane-bounded organelle; and myelin sheath. Is expressed in several structures, including alimentary system; ear; genitourinary system; meninges; and musculature. Orthologous to human CA13 (carbonic anhydrase 13). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 14706787 | 14728062 | Mouse | 101 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1317437 | Car14 | carbonic anhydrase 14 | Enables carbonate dehydratase activity. Predicted to act upstream of or within carbon dioxide transport and regulation of pH. Predicted to be located in apical plasma membrane and basolateral plasma membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including ce ntral nervous system; cranium; early conceptus; sensory organ; and urinary system. Orthologous to human CA14 (carbonic anhydrase 14). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 95805080 | 95812443 | Mouse | 136 | symbol , PhenoGen | gene, protein-coding, VALIDATED [RefSeq] |
| 1306018 | Car15 | carbonic anhydrase 15 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INTERACTS WITH manganese(II) chloride | 11 | 96651439 | 96654384 | Rat | 8 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1314394 | Car15 | carbonic anhydrase 15 | Enables carbonate dehydratase activity. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; respiratory system; sensory organ; and urinary system. [provided by Alliance of Genome Resources, Jul 2025] | 16 | 17653140 | 17656050 | Mouse | 23 | symbol , PhenoGen | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1597710 | Car13l1 | carbonic anhydrase 13 like 1 | | 6 | 6361667 | 6369693 | Rat | | symbol , PhenoGen | gene, protein-coding, MODEL [RefSeq] |
| 1598099 | Car13-ps2 | carbonic anhydrase 13, pseudogene 2 | | 6 | 55123621 | 55127694 | Rat | | symbol , PhenoGen | gene, pseudo, MODEL [RefSeq] |
| 1317265 | ADAM12 | ADAM metallopeptidase domain 12 | This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of th is gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form. [provided by RefSeq, Jan 2014] | 10 | 126012391 | 126388477 | Human | 151 | old_gene_symbol | gene, protein-coding, REVIEWED [RefSeq] |
| 735155 | Ca11 | carbonic anhydrase 11 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); zinc ion binding (inferred); ASSOCIATED WITH COVID-19 (ortholog); FOUND IN basolateral plasma membrane (ortholog); INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol | 1 | 105306347 | 105311651 | Rat | 88 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1306612 | Ca12 | carbonic anhydrase 12 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INVOLVED IN estrous cycle; chloride ion homeostasis (ortholog); ASSOCIATED WITH colon adenocarcinoma (ortholog); colorectal adenocarcinoma (ortholog); colorectal carcin oma (ortholog); FOUND IN apical plasma membrane; basolateral plasma membrane; INTERACTS WITH 17beta-estradiol; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine | 8 | 76169723 | 76225465 | Rat | 186 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1560453 | Ca13 | carbonic anhydrase 13 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; acetamide; bisphenol A | 2 | 88649643 | 88680763 | Rat | 101 | old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1599277 | Ca14 | carbonic anhydrase 14 | ENCODES a protein that exhibits carbonate dehydratase activity (inferred); lyase activity (inferred); metal ion binding (inferred); ASSOCIATED WITH Zinc Deficiency; FOUND IN apical plasma membrane; basolateral plasma membrane; INTERACTS WITH (+)-schisandrin B; 6-propyl-2-thiouracil; acrylamide | 2 | 186131196 | 186138164 | Rat | 123 | old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 15003242 | AABR07063126.1 | carbonic anhydrase 13 like 1 | | | | | Rat | | old_gene_symbol | gene, processed_pseudogene |
| 284505611 | XB5797209 [provisional:car15] | | | | | | Tropical Clawed Frog | | symbol | gene, null |
