Car15 (carbonic anhydrase 15) - Rat Genome Database

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Gene: Car15 (carbonic anhydrase 15) Mus musculus
Analyze
No known orthologs.
Symbol: Car15
Name: carbonic anhydrase 15
RGD ID: 1314394
MGI Page MGI
Description: Exhibits carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Localizes to anchored component of plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; respiratory system; and sensory organ; INTERACTS WITH 1,2-dichloroethane; 1,2-dimethylhydrazine; carbon nanotube.
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: AI315043; Ca; CA-XV; Ca15; Cals2; carbonate dehydratase XV; carbonic anhydrase XV; carbonic anhydrase-like sequence 2
RGD Orthologs
Alliance Genes
More Info homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391617,653,140 - 17,656,050 (-)NCBIGRCm39mm39
GRCm39 Ensembl1617,653,140 - 17,656,228 (-)Ensembl
GRCm381617,835,276 - 17,838,186 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,835,276 - 17,838,364 (-)EnsemblGRCm38mm10GRCm38
MGSCv371617,835,369 - 17,838,279 (-)NCBIGRCm37mm9NCBIm37
MGSCv361617,748,839 - 17,751,749 (-)NCBImm8
Celera1618,408,345 - 18,411,255 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1611.05NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
1. MGD data from the GO Consortium
2. RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:10349636   PMID:10704284   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14681479   PMID:15489334   PMID:16083424   PMID:16141072  
PMID:16141073   PMID:17362527   PMID:17626619   PMID:18336313   PMID:19193158   PMID:20224780   PMID:20820888   PMID:21267068   PMID:21873635   PMID:23233153   PMID:33197428  


Genomics

Position Markers
Car15  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map16A3UniSTS
cM Map16 UniSTS
UniSTS:237451  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381617,835,281 - 17,835,491UniSTSGRCm38
MGSCv371617,835,374 - 17,835,584UniSTSGRCm37
Celera1618,408,350 - 18,408,560UniSTS
Cytogenetic Map16A3UniSTS
cM Map1610.36UniSTS
AI315043  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381617,835,647 - 17,835,796UniSTSGRCm38
MGSCv371617,835,740 - 17,835,889UniSTSGRCm37
Celera1618,408,716 - 18,408,865UniSTS
Cytogenetic Map16A3UniSTS
cM Map1610.36UniSTS
Whitehead/MRC_RH16142.4UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4141060Pbwg19_mpostnatal body weight growth 19 (mouse)Not determined16120963024Mouse
1300632Loca2_mlocomotor activity 2 (mouse)Not determined16122682710Mouse
10043879Adip25_madiposity 25 (mouse)Not determined16122702454Mouse
1301575Tanidd3_mtally ho associated non-insulin dependednt diabetes mellitus 3 (mouse)Not determined16123079875Mouse
1301970Heal11_mwound healing/regeneration 11 (mouse)Not determined16124445989Mouse
4141468Nhdlq10_mnon-HDL QTL 10 (mouse)Not determined16124445989Mouse
1301384Dice1_mdetermination of interleukin 4 commitment 1 (mouse)Not determined16128616494Mouse
10402497Lmr23_mleishmaniasis resistance 23 (mouse)Not determined16129856336Mouse
1301559Bbaa19_mB.burgdorferi-associated arthritis 19 (mouse)Not determined16130249113Mouse
10412289Ppsl_mplasma P-selectin levels (mouse)Not determined16130996708Mouse
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16350000040000000Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16350000051600000Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16350000064800000Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16400000064800000Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16450000044700000Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16482756438827664Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16595650239956690Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16595650239956690Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16595650239956690Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16595650239956690Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16665914535200846Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16672511565669666Mouse
4142460Nilac10_mnicotine induced locomotor activity 10 (mouse)Not determined16731904229406653Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16840730242407302Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16860000091100000Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined161006288144062881Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161203007246030171Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161240654246406653Mouse
15092082Igly9_mIgG glycosylation 9, GP17b (mouse)161495735920284763Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161498410348984214Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161570409149704294Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:137
Count of miRNA genes:132
Interacting mature miRNAs:137
Transcripts:ENSMUST00000118960
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000118960   ⟹   ENSMUSP00000113400
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1617,835,276 - 17,838,364 (-)Ensembl
RefSeq Acc Id: ENSMUST00000231865
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1617,835,277 - 17,836,056 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232516
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1617,836,551 - 17,837,574 (-)Ensembl
RefSeq Acc Id: ENSMUST00000232529
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl1617,835,939 - 17,837,393 (-)Ensembl
RefSeq Acc Id: NM_030558   ⟹   NP_085035
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391617,653,140 - 17,656,050 (-)NCBI
GRCm381617,835,276 - 17,838,186 (-)NCBI
MGSCv371617,835,369 - 17,838,279 (-)RGD
Celera1618,408,345 - 18,411,255 (-)RGD
cM Map16 ENTREZGENE
Sequence:
Protein Sequences
Protein RefSeqs NP_085035 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH19975 (Get FASTA)   NCBI Sequence Viewer  
  AAK16671 (Get FASTA)   NCBI Sequence Viewer  
  BAE20923 (Get FASTA)   NCBI Sequence Viewer  
  EDK97485 (Get FASTA)   NCBI Sequence Viewer  
  Q99N23 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_085035   ⟸   NM_030558
- Peptide Label: precursor
- UniProtKB: Q99N23 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000113400   ⟸   ENSMUST00000118960
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:8685634
Promoter ID:EPDNEW_M20848
Type:initiation region
Name:Car15_1
Description:Mus musculus carbonic anhydrase 15 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381617,838,213 - 17,838,273EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1931324 AgrOrtholog
Ensembl Genes ENSMUSG00000090236 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000113400 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000118960 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CA4/CA15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CA_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Carbonic_anhydrase_CA15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:80733 UniProtKB/Swiss-Prot
MGD MGI:1931324 ENTREZGENE
NCBI Gene 80733 ENTREZGENE
PANTHER PTHR18952 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR18952:SF134 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Car15 PhenoGen
PROSITE ALPHA_CA_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART Carb_anhydrase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt CAH15_MOUSE UniProtKB/Swiss-Prot
  Q3V275_MOUSE UniProtKB/TrEMBL
  Q99N23 ENTREZGENE