Car13 (carbonic anhydrase 13) - Rat Genome Database

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Gene: Car13 (carbonic anhydrase 13) Mus musculus
Analyze
Symbol: Car13
Name: carbonic anhydrase 13
RGD ID: 1322169
MGI Page MGI
Description: Enables carbonate dehydratase activity. Predicted to be involved in one-carbon metabolic process. Located in cytosol; intracellular membrane-bounded organelle; and myelin sheath. Is expressed in several structures, including alimentary system; ear; genitourinary system; meninges; and musculature. Orthologous to human CA13 (carbonic anhydrase 13); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310075C21Rik; CA-XIII; Ca13; carbonate dehydratase XIII; carbonic anhydrase XIII
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,706,787 - 14,728,062 (+)NCBIGRCm39mm39
GRCm39 Ensembl314,706,787 - 14,728,062 (+)Ensembl
GRCm38314,641,727 - 14,663,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,641,727 - 14,663,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,641,727 - 14,663,002 (+)NCBIGRCm37mm9NCBIm37
MGSCv36314,618,518 - 14,639,139 (+)NCBImm8
Celera314,649,523 - 14,670,798 (+)NCBICelera
Cytogenetic Map3A1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:10349636   PMID:11042159   PMID:11076861   PMID:12477932   PMID:14600151   PMID:14681479   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:17362527   PMID:17626619  
PMID:20820888   PMID:21267068   PMID:21677750   PMID:21873635   PMID:23233153   PMID:24194600   PMID:24789143   PMID:30305733  


Genomics

Comparative Map Data
Car13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,706,787 - 14,728,062 (+)NCBIGRCm39mm39
GRCm39 Ensembl314,706,787 - 14,728,062 (+)Ensembl
GRCm38314,641,727 - 14,663,002 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,641,727 - 14,663,002 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,641,727 - 14,663,002 (+)NCBIGRCm37mm9NCBIm37
MGSCv36314,618,518 - 14,639,139 (+)NCBImm8
Celera314,649,523 - 14,670,798 (+)NCBICelera
Cytogenetic Map3A1NCBI
CA13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl885,220,587 - 85,284,073 (+)EnsemblGRCh38hg38GRCh38
GRCh38885,245,458 - 85,284,073 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37886,157,687 - 86,196,302 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,345,259 - 86,383,554 (+)NCBINCBI36hg18NCBI36
Build 34886,345,258 - 86,383,554NCBI
Celera882,162,764 - 82,201,350 (+)NCBI
Cytogenetic Map8q21.2NCBI
HuRef881,651,766 - 81,690,497 (+)NCBIHuRef
CHM1_1886,209,312 - 86,248,027 (+)NCBICHM1_1
Ca13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2286,928,401 - 86,959,525 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl286,928,383 - 86,959,525 (-)Ensembl
Rnor_6.0288,282,961 - 88,314,254 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl288,282,961 - 88,314,254 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02108,055,053 - 108,086,130 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,271,908 - 88,309,336 (-)NCBIRGSC3.4rn4RGSC3.4
Celera282,519,345 - 82,549,951 (-)NCBICelera
Cytogenetic Map2q23NCBI
Ca13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,194,501 - 3,219,755 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,194,961 - 3,219,019 (+)NCBIChiLan1.0ChiLan1.0
CA13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1883,381,011 - 83,419,335 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl883,381,011 - 83,419,446 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0881,770,852 - 81,809,750 (+)NCBIMhudiblu_PPA_v0panPan3
CA13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,784,614 - 31,833,429 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,782,680 - 31,850,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2932,067,124 - 32,112,791 (+)NCBI
ROS_Cfam_1.02931,932,517 - 31,980,427 (+)NCBI
UMICH_Zoey_3.12931,988,167 - 32,033,742 (+)NCBI
UNSW_CanFamBas_1.02932,006,949 - 32,052,786 (+)NCBI
UU_Cfam_GSD_1.02932,390,753 - 32,439,552 (+)NCBI
Ca13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,586,067 - 47,615,381 (-)NCBI
SpeTri2.0NW_004936544177,336 - 206,638 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CA13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,407,473 - 51,468,961 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,406,755 - 51,468,971 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,422,548 - 56,483,985 (-)NCBISscrofa10.2Sscrofa10.2susScr3
CA13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,617,375 - 80,654,408 (+)NCBI
ChlSab1.1 Ensembl880,617,898 - 80,651,692 (+)Ensembl
Vero_WHO_p1.0NW_02366603960,445,939 - 60,482,960 (-)NCBI
Ca13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247446,418,487 - 6,447,023 (-)NCBI

Position Markers
Car13  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3A2UniSTS
cM Map3 UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301256Skmw1_mskeletal muscle weight 1 (mouse)Not determined3125721372Mouse
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33200000142700000Mouse
1300559Thypr3_mthymocyte proliferative response 3 (mouse)Not determined3447125538471355Mouse
1558925Hivan1_mHIV-associated nephropathy 1 (mouse)Not determined3752111468809613Mouse
4142399Aec1_mautoimmune exocrinopathy 1 (mouse)Not determined7521114102782718Mouse
4141563Lgq3_mlate growth QTL 3 (mouse)Not determined1018416183277639Mouse
1357440Hrtpq1_mheart weight percentage QTL 1 (mouse)Not determined31018416183277639Mouse
1357857Lvrq5_mliver weight QTL 5 (mouse)Not determined31018416183277639Mouse
1357584Splq6_mspleen weight QTL 6 (mouse)Not determined31018416183277639Mouse
4141116Lgaq4_mlate growth adjusted QTL 4 (mouse)Not determined1018416183277639Mouse
4141255W10q3_mweight 10 weeks QTL 3 (mouse)Not determined1018416183277639Mouse
39128206Lwq18_mliver weight QTL 18 (mouse)31018416183277639Mouse
1301358Eae20_mexperimental allergic encephalomyelitis 20 (mouse)Not determined31157630445576442Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:326
Count of miRNA genes:274
Interacting mature miRNAs:293
Transcripts:ENSMUST00000029071
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_024495 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC167976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF231123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK010166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK150897 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151978 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK152124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK162621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186680 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK209857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214319 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064050 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000029071   ⟹   ENSMUSP00000029071
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl314,706,787 - 14,728,062 (+)Ensembl
GRCm38.p6 Ensembl314,641,727 - 14,663,002 (+)Ensembl
RefSeq Acc Id: NM_024495   ⟹   NP_078771
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39314,706,787 - 14,728,062 (+)NCBI
GRCm38314,641,727 - 14,663,002 (+)ENTREZGENE
MGSCv37314,641,727 - 14,663,002 (+)RGD
Celera314,649,523 - 14,670,798 (+)RGD
cM Map3 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_078771   ⟸   NM_024495
- UniProtKB: Q9D6N1 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000029071   ⟸   ENSMUST00000029071
Protein Domains
Alpha-carbonic anhydrase

Promoters
RGD ID:6833529
Promoter ID:MM_KWN:33793
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   MEF_B4
Transcripts:NM_024495
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36314,641,731 - 14,642,231 (+)MPROMDB
RGD ID:6880260
Promoter ID:EPDNEW_M3581
Type:initiation region
Name:Car13_1
Description:Mus musculus carbonic anhydrase 13 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38314,641,776 - 14,641,836EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1931322 AgrOrtholog
Ensembl Genes ENSMUSG00000027555 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000029071 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000029071 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.200.10 UniProtKB/Swiss-Prot
InterPro CA_dom UniProtKB/Swiss-Prot
  CA_dom_sf UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class UniProtKB/Swiss-Prot
  Carbonic_anhydrase_a-class_CS UniProtKB/Swiss-Prot
KEGG Report mmu:71934 UniProtKB/Swiss-Prot
MGD MGI:1931322 ENTREZGENE
NCBI Gene 71934 ENTREZGENE
PANTHER PTHR18952 UniProtKB/Swiss-Prot
Pfam Carb_anhydrase UniProtKB/Swiss-Prot
PhenoGen Car13 PhenoGen
PROSITE ALPHA_CA_1 UniProtKB/Swiss-Prot
  ALPHA_CA_2 UniProtKB/Swiss-Prot
SMART Carb_anhydrase UniProtKB/Swiss-Prot
Superfamily-SCOP SSF51069 UniProtKB/Swiss-Prot
UniProt CAH13_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q3UBM2 UniProtKB/Swiss-Prot